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Meat replacement startup Heura has a new mission to slay junk food with healthier plant-based swaps

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Meat replacement startup Heura has a new mission to slay junk food with healthier plant-based swaps

The offices of plant-based protein startup Heura are tucked away down a narrow street a short distance from one of Barcelona’s main tourist draws. But the team of entrepreneurs and food scientists won’t be remixing their protein cocktails in close proximity to La Sagrada Família for much longer — they’re moving to new, larger digs in Poblenou, a district where industrial-scale office space is a lot easier to come by.

As we’re shown around the “Heura House :)”, as the startup’s HQ is named (complete with beaming smilie), you can see why they want a bit more room to cook stuff up. A lower level of the narrow building is packed with lab machinery where a multi-disciplined team of scientists is developing the bases and textures that will underpin future food products. Up a metal staircase are two floors of office desks and meeting rooms and, higher still, a conference-room sized kitchen spans the back of the building. This is where foods can be prepared for tasting and presented on a large stainless steel table.

This is where TechCrunch meets Heura’s CEO and founder Marc Coloma and chief scientist Isa Fernández after getting a whistle-stop tour of the labs where the startup is working to serve up a smorgasbord of food IP.

Heura’s looming office move is not just a tale of a scaling startup outgrowing its digs. It coincides with a shift in strategy as the company gears up to use patent-pending blends of plant-based proteins to try to address another huge problem for the mainstream food industry: the poor nutritional quality of so much processed and packaged food.

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This strategic shift beyond (pure) meat replacement looks smart. Focussing on nutrition and health may be a more mainstream-friendly way for Heura to get more people to reduce their meat and dairy consumption by buying into healthier substitutes that just happen to be vegan.

“What we are focused on is creating structures and matrices in many of the most consumed food categories, through plant proteins, and then also developing technologies that will help us to decrease costs of these formulations and increase the sensory aspect,” Coloma tells TechCrunch. “To keep improving flavor, keep improving taste — while reducing costs.”

Its €40 million Series B is helping juice the new strategy which will see it licensing its inventions to food manufacturers wanting to improve the quality of the products they sell, as well as bringing more new products to market under Heura’s own yellow-liveried consumer-facing brand.

One of Heura’s lab rooms where a multidisciplinary team is taking a “science-based approach” to reformulating a range of foodstuffs (Image credits: Natasha Lomas/TechCrunch)

Targeting the food industry’s quality problem

The problem Heura is setting its sights on is that industrially produced food is pretty often quite unhealthy, formulated with “no protein, high saturated fat, high sodium, no fiber,” says Coloma.

Such products were once generally referred to as junk foods. More recently there’s been a shift to defining the problem by applying a more scientific-sounding (less judgemental?) badge of ‘ultra processed food’ (UPFs).

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UPFs is an imperfect label that tries to bundle up common industrial food techniques like refining, which removes healthy fiber and amps up simple sugars, and extensive use of additives, which can upset gut health and have other health impacts. The core problem Herua has in its sights, by targeting UPFs, can thus be boiled down to convenience foods that last long on shelves but have low nutritional density and are increasingly linked to poor health outcomes for consumers.

Heura is aiming to maintain convenience while ditching the junk by applying what it calls a “science-based approach” to reformulate a range of familiar foodstuffs in such a way as to avoid nutritional pitfalls. It’s doing this via a scientific process of microstructural design which it says allows it to control interactions between ingredients to yield foodstuffs with pleasant textures and an “amazing” nutritional composition, as Coloma tells it.

The thermo-mechanical techniques it’s using to process its selected plant-based ingredients are not different to standard food industry methods. Instead, the startup claims the innovation is in the level of micro-control it’s applying to designing food structures and interactions in order to serve up nutritionally dense foods with a great sensory experience. Or, put more simply, it’s designing foods that are healthy — or at least less unhealthy than conventional alternatives — but which are also enticing to eat.

“What we are doing is making the soy protein aggregate interact within itself in a specific way that nobody has been able to do through controlling processing conditions and then pH, [calcium] ions and things like that,” explains Fernández, discussing the work Heura’s scientists are undertaking in the lab. “So it’s all the scientific knowledge that we generate [which] allows us to create these micro structures — using, again, specific protein analytes that gives these textures.”

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The food industry isn’t set up to take such an approach, argues Coloma, who says big players are mainly focused on product development. They’re looking at remixing available processing solutions plus functional ingredients, rather than changing the mix and micro-structure of ingredients to alter the nutritional profile of foods.

“They don’t know how to do it,” he suggests. “From a technology perspective, this holistic approach — about interactions — requires you to have a trans-disciplinary and holistic knowledge about many scientific disciplines. And this is not common.”

“And it’s not easy,” Fernández chips in. “We have a lot of people that have been looking at this problem, including me, for a long time.”

Using standard processing techniques in a way that can deliver novel food outcomes is how Heura is banking on achieving mass scale for this expansion into licensing its IP.

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“Why we take this route is because this can make a mass market product,” says Coloma. “Because it’s scalable using industrial process that are simple and then with raw materials that are very available. We really believe in this route of interactions in order to unleash scalability.”

A long tail of poor nutrition

Poor nutritional value is not limited to packaged foods that contain animal-derived ingredients, of course. It’s a problem that cuts across the industrial food industry — from pot noodles to packets of ham and processed cheese to hot dogs and frozen pizza and beyond — and the plant-based category certainly hasn’t been immune.

In the vegan food aisle, heavy use of ingredients like modified starches which end up as simple carbohydrates, high levels of sodium (salt), and saturated fats like coconut oil can result in plant-based foods with poor health profiles. The meat lobby has often seized on such products to attack the alternative protein category generally. Such attacks ignore the existence of better quality vegan foods and seek to redirect attention away from the fact that many animal-derived packaged foods are cardinal UPFs themselves.

Nutritional problems for meat and dairy can include high saturated fat content, high sodium, low fiber and the use of additives (including things like antibiotics and growth hormones that may be fed to livestock) — while meat processing techniques can further exacerbate problems, such as curing amping up salt content and preservatives or frying leading to the formation of harmful compounds.

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In the case of processed ham and other red meats these products have been classified as carcinogenic to humans. You’ll just never hear the meat lobby harping about that.

The alternative plant-based formulations Heura is cooking up aim to address the food industry’s quality problem broadly — cutting across categories, both animal-derived and plant-based — with the aim of driving positive change at industrial food scale.

The Barcelona-based startup is best known for its own brand meat replacement products, especially its chicken-style soy-based bites. Last year, it added plant-based Jamon York-style slices to its range. And that latter cold cuts product, which it’s been selling in Europe since October 2023, was the first developed through its new R&D intensive approach.

Coloma showing the ingredients list on the back of a packet of Heura’s plant-based Jamon York (Image credits: Natasha Lomas/TechCrunch)

In the future, Heura will be expanding its efforts to commercialize a pipeline of lab-based inventions so it can reformulate many more types of foods. It says it’s setting its sights on “the most consumed” food categories — with cheese and pasta seemingly next in line for nutritional remixing.

Coloma jokily says they’ll start by drawing up a list of the “ten worst” UPFs to choose where to start. “We are already seeing that around 30% of people are looking for healthier options of the food that they love,” he adds. “So it’s changing the foods that they love without changing the taste.”

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In Heura’s brightly lit demo kitchen, TechCrunch had the chance to sample a few of the prototypes Fernández and her team have been developing in the basement. Including some (tasty) Feta-style chunks and mini Mozzarella-esque balls. We also tried three other cheese prototypes, which ranged in texture from medium/chewy to softer.

The startup is keeping the full scope of its expansion plans under wraps for now because it still has multiple patents to file. But Coloma did let slip that future products formulated through this approach will include “indulgent” foods — his eye straying to a bank of frosted glass refrigerators at the side of the kitchen. So it sounds as if desserts could be in the mix too. (Protein-boosted vegan ice-cream is already a thing, after all.)

“Our vision is to become the Intel Inside for high value nutrition with amazing taste,” he told us, trying out the mouthfeel of a soundbite that Heura’s marketing team must have been cooking up in parallel to its lab-coated staff.

A twist on very familiar foodstuffs

Heura stressed that the prototype foods TechCrunch tasted were not yet finished products. These samples offered an early glimpse of what’s coming as it expands its plant-based range — so, essentially, we were getting a demo of texture and mouthfeel possibilities.

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Fernández emphasized that no active flavors had been added beyond some herbs floating in oil in a jar of the faux Feta (hence that one stood out as tasty). All that work comes later when the product development team takes over from the food scientists, she noted.

Per Coloma, the prototypes also won’t make it to market for some years yet either. 2026 is the anticipated timeframe for Heura to commercialize this next wave of R&D. So we’re reserving judgement on the startup’s plant-based cheeseboard for now. But the selection we tried showed that textural variety is possible. Even as some of the samples tended towards more of a paté mouthfeel than a conventional cheese.

For another tasting, another staffer cooked us up a plate of reformulated spaghetti. The pasta looked and tasted exactly as you’d expect a conventional spaghetti (and was pleasingly al dente). But the twist is the pasta has been enriched with Heura’s legume-based protein — boosting the protein content of the dish up to 50% (whereas Coloma noted that pasta in mainstream foods typically contains 10% or less protein; or, for a higher quality pasta, 17% protein at the top end).

Heura is also adding fiber to its alternative formulations as another nutritional upgrade. Modern Western diets are known to be chronically short of fiber — which plays a key role in digestive and gut health, with many associated benefits including helping regulate blood glucose which also links to weight management and cardiovascular health.

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Exact advantages of Heura’s formulations compared to the conventional foods it’s aiming to replace (or supplant) will vary. But in the case of the cheese products Coloma suggests its plant-based nutritional blends will be much healthier than conventional dairy-based cheese on account of not being larded with saturated fats.

Image credits: Heura

Vegan cheeses that use coconut oil can have even higher levels of saturated fats than dairy-based cheese. So Heura is also able to offer its alternative blend of proteins and fats to other vegan food makers to improve their products. (Indeed, it already is: Coloma notes it’s inked a “collaboration agreement” with Upfield, which owns the Violife plant-based cheese brand for example — a faux hard cheese product that can have a bottom-of-the-range Nutri-Score of E (“bad nutritional quality”), per Open Food Facts.)

When it comes to taste and texture, whether plant-based cheeses will ever really be able to mimic the experience and mouthfeel of conventional dairy remains to be seen. A growing number of startups in the precision fermentation space are growing bio-identical proteins to animal-based cheese. They suggest that making similarly tasty alternatives to conventional cheese is no cakewalk. But even taking a chunk out of conventional dairy could mean big business for Heura’s plant-based remixers.

The startup is experimenting with traditional fermentation in its labs. But Coloma said that it’s more about exploring ways to use bacterias instead of aromas for flavor — the latter are expensive. It doesn’t plan to get into the precision fermentation game, he confirmed.

For Heura’s already-on-sale ham-style slices, its science-based approach has delivered a high convenience product that’s popular because it mimics the taste and look (and gelatinous feel) of the processed meat products it aims to replace. (We also got to nibble on a sample of this and found it uncannily meat-like.)

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Heura’s Jamon York-style cold cuts is the first product it’s commercialized through the science-based approach (Image credits: Natasha Lomas/TechCrunch)

A tasty new health-focused strategy?

So will Heura be able to pull off similar nutritional swaps across many more food categories? When it comes to pasta, its planned formula has much more protein but, in our experience tasting the prototype, looks, tastes, smells (and moves) just like real spaghetti — so it seems like a clear win-win.

Disrupting dairy-based cheese is probably going to be more complex. At a minimum, there are still textural differences between Heura’s plant-based versions and conventional cheeses. Plus the prototypes we sampled won’t melt like real cheese — although we’re told some can be grilled, Halloumi-style.

It’s fair to say a cheese connoisseur will be hard to convince by plant-based substitutes. But Heura isn’t going after the artisanal end of the market. It’s more likely to be targeting a product such as a supermarket own-brand plastic bag of shredded mozzarella which costs a few euros. So there’s a lower food comparison bar to meet.

Its plant-based cheeses could also offer a cheaper ingredient for food manufacturers on account of using lower cost (and healthier) fats. Although Heura says cost changes from its formulations will vary per product and Coloma admits there could be situations where very poor quality foods remain cheaper still. (“If it’s really, really cheap — because they are using really cheap ingredients — there will be more difficulty [to undercut or achieve price parity],” he says. “But in some we can even be more efficient.”)

Heura’s biggest boast for forthcoming products made using its patent-pending IP is the claim of a healthier nutritional profile than conventional fare.

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How the food industry will react to this pitch remains to be seen. But companies do have a range of commercial reasons to take an interest, especially as food makers are under growing pressure to find ways to reduce their carbon footprint. And swapping animal-based cheese with Heura’s plant-based alternative could rapidly improve a dairy product’s environmental impact, for example.

Additionally, there is a trend of rising awareness and interest among consumers about how healthy particular foods are. It could nudge more food makers to investigate swaps that can be marketed to consumers as better for them than the usual version.

Given such pressures — and assuming Heura is able to smoothly translate its lab work into a defensible portfolio of enticing food IP — it’s not too hard to imagine it could end up cutting itself a bigger slice of the food pie in the coming years.

Still, Coloma cautions it will take time to build up a licensing business as established food industry processes (and supply chains) clearly won’t flip overnight.

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“This is our dream,” he says, when asked whether Heura is working towards the assumption that this licensing play will end up being the bigger portion of its business in the future. “We went into technology in order to open and license these solutions to other big players that already have a scale that we have to build [as a food startup].”

“The issue here… is that it takes a lot of time… This is a technology about the processing of the product, so we have to develop the product for them; get the agreement; get launched into the market; test and scale — so it will be processes, normally, of two to three years [to commercialize IP from lab to plate]. But from 10 years’ perspective, what you said, it could be a scenario.”

Coloma, who has a background in food activism, emphasizes that their goal with the new strategy is to push into many more food categories in order to dial up its ability to have a positive impact on the food system as a whole, both for food consumers and for the environment.

And while there are other food-tech startups with the same mission that are exploring even more radical protein bases than plants, Heura doesn’t have to wait for regulatory sign off to get its foods onto people’s plates. Coloma also argues that legume proteins are hard to beat when it comes to scaling high quality nutrition cost effectively — being orders of magnitude more efficient, in terms of land and resource use, than the animal-derived ingredients it wants to edge out.

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A manifesto that looms several meters high on the Heura House stairwell inks the scale of its ambition in white-on-black block text. “We are the generation who will stop the exploitation of animal sources by delivering incredibly delicious plant based meat,” it reads.

Heura’s freshly expanded mission means its marketing team may soon need to sub out the word “meat” — and swap in “meals”.

When the company closed its Series B round earlier this year it set out a plan to reach net profitability by Q3 of next year. Coloma says the business is on track with that goal, noting that as well as using the money to expand its technology and IP portfolio they have been focusing on growing retail sales of their own brand meat replacement products around Europe.

“We are very focused in France, in Italy, in Portugal,” he says, noting its top three products currently are its faux chicken, plant-based burgers and the alternative Jamon York. “We are advancing a lot towards being the leader in the analogous category in the south of Europe. That’s advancing well… With the growth, with the structure that we have, we can reach profitability.”

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This video gives instructions on how to install the new slide rails on rackmount enclosure.

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Vera AI launches ‘AI Gateway’ to help companies safely scale AI without the risks

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Vera AI launches 'AI Gateway' to help companies safely scale AI without the risks

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Vera AI Inc., a startup focused on responsible artificial intelligence deployment, announced today the general availability of its AI Gateway platform. The system aims to help organizations more quickly and safely implement AI technologies by providing customizable guardrails and model routing capabilities.

“We’re really excited to be announcing the general availability of our model routing and guardrails platform,” said Liz O’Sullivan, CEO and co-founder of Vera, in an interview with VentureBeat. “We’ve been hard at work over the last year building something that could scalably and repeatably accelerate time to production for the kinds of business use cases that actually stand to generate a lot of excitement.”

Vera AI’s policy configuration interface, showcasing the platform’s granular content moderation tools. The dashboard allows companies to customize AI safeguards, balancing the need for innovation with responsible content management — a key selling point in Vera’s mission to make AI deployment both efficient and ethical. (Credit: Vera)

Bridging the gap: How Vera’s AI gateway tackles last-mile challenges

The launch comes at a time when many companies are eager to adopt generative AI and other advanced AI technologies, but remain hesitant due to potential risks and challenges in implementing safeguards. Vera’s platform sits between users and AI models, enforcing policies and optimizing costs across different types of AI requests.

“Businesses are only ever interested in doing one of three things, whether that’s make more money, save more money, or reducing risk,” O’Sullivan explained. “We’ve focused ourselves squarely on the last mile problems, which people think, just like regular software engineering, that it’s going to be quick and easy, that these are just afterthoughts that you can apply to optimize costs or to reduce risks associated with things like disinformation and broad and CSAM, but they’re actually quite hard.”

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Justin Norman, CTO and co-founder of Vera, emphasized the importance of nuance in AI policy implementation: “You want to be able to set the bar for where your system will respond and where it will not respond and what it will do, without having to rely upon what some other companies made a decision for you on.”

Vera AI’s interface demonstrates its content moderation capabilities, blocking a user’s input that failed to follow the specified rules — a key feature in the company’s mission to provide guardrails for responsible AI deployment. (Credit: Vera)

From AI safety activism to startup success: The minds behind Vera

The company’s approach appears to be gaining traction. According to O’Sullivan, Vera is already “processing tens of thousands of model requests per month across a handful of paying customers.” The startup offers API-based pricing at one cent per call, aligning its incentives with customer success in AI deployment.

Vera’s launch is particularly noteworthy given the founders’ backgrounds. O’Sullivan, who serves on the National AI Advisory Committee, has a history of AI safety activism, including her work at Clarifai. Norman brings experience from government, academia, and industry, including PhD work at UC Berkeley focused on AI robustness and evaluation.

Navigating the AI safety landscape: Vera’s role in responsible innovation

As AI adoption accelerates across industries, platforms like Vera’s could play a crucial role in addressing safety and ethical concerns while enabling innovation. The startup’s focus on customizable guardrails and efficient model routing positions it well to serve both enterprise clients managing internal AI use and companies developing consumer-facing AI applications.

However, Vera faces a competitive landscape with other AI safety and deployment startups also vying for market share. The company’s success will likely depend on its ability to demonstrate clear value to customers and stay ahead of rapidly evolving AI technologies and associated risks.

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For organizations looking to responsibly implement AI, Vera’s launch offers a new option to consider. As O’Sullivan put it, “We’re here to make it as easy as possible to enjoy the benefits of AI while reducing the risks that things do go wrong.”


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OpenAI raises $6.6B and is now valued at $157B

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OpenAI CEO Sam Altman speaks during the OpenAI DevDay event on November 06, 2023 in San Francisco, California.

ChatGPT maker OpenAI has closed the largest VC round of all time.

The startup today announced that it raised $6.6 billion in a funding round that values OpenAI at $157 billion post-money. Led by previous investor Thrive Capital, the new cash brings OpenAI’s total raised to $17.9 billion, per Crunchbase.

Thrive invested around $1.3 billion, per The New York Times, with an exclusive option to invest up to $1 billion more at the same valuation (through 2025). Microsoft, Nvidia, SoftBank, Khosla Ventures, Altimeter Capital, Fidelity, and MGX also participated in the fundraising.

“The new funding will allow us to double down on our leadership in frontier AI research, increase compute capacity, and continue building tools that help people solve hard problems,” the company wrote in a blog post. “We’re grateful to our investors for their trust in us, and we look forward to working with our partners, developers, and the broader community to shape an AI-powered ecosystem and future that benefits everyone.”

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There may be unusual strings attached. This morning, the Financial Times reported that OpenAI asked investors to avoid backing rival startups such as Anthropic and xAI. We’ve reached out to the company for more information and will update this post when we hear back.

OpenAI was already the world’s best-funded AI startup. But the mammoth new tranche puts the San Francisco company in a category all its own.

Elon Musk’s AI venture, the aforementioned xAI, raised over $6 billion earlier this year, but at a valuation dwarfed by OpenAI’s ($24 billion post-money). Chief OpenAI rival Anthropic has secured just over half OpenAI’s total ($9.7 billion) since its founding, while high-profile AI ventures Cohere and Mistral’s capital war chests are hovering around $1 billion.

So why did OpenAI need to raise more cash than the government of Zimbabwe spent in 2021? Well, quite simply, to sustain its sprawling operations. OpenAI is reportedly burning through billions training and productizing its AI systems — systems like the recently debuted o1 — and recruiting coveted data science talent to stay apace with the competition.

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According to The Information, OpenAI has spent roughly $7 billion on model training and $1.5 billion on staffing. (OpenAI CEO Sam Altman has said that one of the company’s older leading models, GPT-4, cost more than $100 million to train.) And at one point in time, ChatGPT alone was said to be costing OpenAI $700,000 a day to run.

OpenAI is far and away the market leader in generative AI. ChatGPT has more than 250 million users (around 10 million of which are paying subscribers), and OpenAI’s annualized revenue has reportedly eclipsed $3.4 billion. ChatGPT alone could bring in $2.7 billion this year, The New York Times reports, citing internal OpenAI docs.

Microsoft, OpenAI’s close partner and investor (it’s put in over $13 billion), has built an entire suite of productivity products on top of OpenAI models. And Apple is integrating ChatGPT with its Apple Intelligence lineup of AI technology.

OpenAI optimistically projects its revenue will reach $100 billion in 2029 — matching the current annual sales of Nestlé. But it faces competition on many fronts.

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Startups like Runway and Luma Labs have beat OpenAI to market with high-fidelity video generation models. (OpenAI’s own video model, Sora, is expected to launch sometime this fall.) Anthropic continues to build out an AI product suite to rival ChatGPT. xAI, Google and Amazon are investing heavily in infrastructure to train powerful next-generation models, and Meta — along with upstarts such as Black Forest Labs — continue to release open models on their quest to commoditize text- and image-generating AI.

The competitive pressures are such that OpenAI may steeply increase the price of its premium ChatGPT plan, ChatGPT Plus, from $20 per month to $44 per month by 2029 — and revamp its corporate structure to attract more investments.

The for-profit division of OpenAI is currently governed by a nonprofit that caps investors’ returns. But Altman is said to have signaled that OpenAI will move away from nonprofit governance in the next few months. Reuters reported earlier that the close of the $6.6 billion round was contingent on this, in fact — and Altman possibly receiving equity.

According to Bloomberg, investors in the new round will be able to claw back their cash if OpenAI doesn’t complete the conversion from nonprofit to for-profit within two years. 

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Unfettering its ability to raise could give OpenAI greater freedom to explore capital-intensive, longer-term bets, like AI chips — and entire datacenters — to lessen its reliance on Nvidia. (Nvidia makes the hardware on which OpenAI trains and runs many of its models.) It’ll also refill the company’s coffers to ink licensing agreements with data providers such as Reddit and Condé Nast — agreements that could give OpenAI a competitive edge while at the same time shielding it from IP lawsuits.

Whether it’ll be able to execute is another question. OpenAI’s been shedding high-profile execs in recent weeks, the culmination of disagreements over the company’s direction.

CTO Mira Murati, chief research officer Bob McGrew, and research VP Barret Zoph announced their resignations in late September. Prominent research scientist Andrej Karpathy left OpenAI in February; months later, OpenAI co-founder and former chief scientist Ilya Sutskever quit, along with former safety leader Jan Leike. In August, co-founder John Schulman said he would leave. And Greg Brockman, OpenAI’s president, is on sabbatical through the end of the year.

Of the 13 people who helped found OpenAI in 2015, only three remain.

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Apple is bringing back Sugar for season 2

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Apple is bringing back Sugar for season 2

Another beloved Apple TV Plus show is getting a second season. The streamer announced today that the detective series Sugar, which stars Colin Farrell in the titular role, has been renewed for season 2. It’s not clear yet when the show will return.

Sugar debuted earlier this year. And while it started out as a clever story about a private investigator, a big twist midway through the first season — you can read about it here, but (obviously) spoilers abound — pushed it into sci-fi territory, a space Apple has been very successful in. There aren’t many details about the upcoming season, but in a press release, Apple says that “season two will see Sugar back in Los Angeles, taking on another missing persons case as he continues to look for answers surrounding his missing sister.”

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