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Jobs saved at Newcastle life sciences firm Newcells Biotech amid partial rescue deal

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The university spin-out’s retina business including its specialist team has been acquired – but all other jobs have been lost

The Biosphere in Newcastle

The Biosphere in Newcastle

Jobs have been saved at a Newcastle biotech business after part of the firm was bought out of administration in a partial rescue deal. Cambridge based Axol Bioscience Ltd, a leading provider of stem cell technologies for drug discovery and research, has announced it has acquired the ophthalmology business of Newcells Biotech, a drug discovery partner specialising in the development of in vitro models.

The business swooped for the retina business of Newcells Biotech – based in the Biosphere at Newcastle Helix – following the appointment of administrators at Grant Thornton LLP. The Newcastle University spin out specialises in providing in vitro tools for testing how drugs interact with tissues and was founded 11 years ago by Dr Mike Nicholds and Professor Lyle Armstrong.

The firm, which had 49 employees in 2024, focused on offering models of the retina, kidney and lung and it was also carrying out testing for customers. Use of 3D models attracted interest after the US Food and Drug Administration (FDA) changed its rules four years ago, scrapping the requirement for new drugs to be tested on animals.

The Axol deal includes the specialist team, facilities and intellectual property within the retina division, specifically related to the supply of proprietary iPSC-derived (induced pluripotent stem cell) products and ophthalmology research services to biopharma, biotechnology and customers across Europe and the US. It’s not known how many staff members have transferred to Axol Bioscience, but 18 other jobs have been lost.

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A spokesman for the company said: “On February 12, 2026, insolvency practitioners from Grant Thornton UK Advisory & Tax LLP were appointed as joint administrators of Newcells Biotech Limited. Following their appointment, the joint administrators agreed a sale of the Retina Business of the company as a going concern to Censo Biotechnologies Limited (trading as Axol Bioscience).

“The acquisition will ensure the operations of the Retina Business will continue at the main trading premises in Newcastle and secured the retention of all employees working within that part of the business. The remaining operations of the company ceased on appointment. As a result, it was not economically viable for the joint administrators to continue to employ the remaining members of staff resulting in 18 redundancies.”

Newcells Biotech CEO Mike Nicholds

Newcells Biotech CEO Mike Nicholds(Image: The Bigger Picture Agency Ltd)

Newcells Biotech announced two significant funding rounds during 2024 to expand its work. The investments – including £2.35m in February and £1.2m in May – aimed to help the business build its customer base and develop partnerships with other companies in its field.

Meanwhile, Axol said the acquisition expands its portfolio of models, and also strengthens its position as the leading independent provider of physiologically-relevant in vitro retinal models for ophthalmology drug discovery and safety testing. Axol recently announced a $2.8m financing deal, led by US life sciences investor BroadOak Capital Partners, which is supporting expansion of its US commercial operations, product development and manufacturing scale-up.

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Liam Taylor, CEO of Axol Bioscience, said: “The addition of Newcells’ retinal organoid business is our third acquisition in five years.

He added: “Newcells has developed a highly sophisticated and scalable retinal organoid platform focused on predictive, human-relevant iPSC-derived retinal models that are recognised across the industry. Integrating this capability with Axol’s existing ophthalmology portfolio enables us to offer a broader, more physiologically relevant toolkit to support research.”

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Earnings call transcript: Nexans Q4 2025 misses revenue forecast, stock falls

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Earnings call transcript: Nexans Q4 2025 misses revenue forecast, stock falls

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‘Landmark year’ for Airbus as global demand for aircraft soars

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The company’s workforce grew during the 2025 financial year to more than 165,000 staff around the world

Airbus factory in Broughton

Airbus factory in Broughton(Image: DAVID POWELL/NORTH WALES LIVE)

Airbus has reported a record financial performance over the year amid rising demand for commercial aircraft. The aerospace giant has UK bases in Broughton, in North Wales, where it manufacturers wings for planes and in Filton, South Gloucestershire, where it designs wings, landing gear and fuel systems.

The company’s consolidated results show revenues increased six per cent year-on-year to €73.4bn, while adjusted EBIT – a measure of performance – totalled €7.1bn, compared to €5.3bn in 2024. The 2024 figure included charges of €1.3bn following an in-depth technical review of space programmes.

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Free cash flow before customer financing stood at €4.5bn, with a consolidated net cash position of €12.2bn – up from €11.8bn at year end in 2024.

A total of 793 commercial aircraft were delivered over the year, comprising 93 A220s, 607 A320 Family, 36 A330s and 57 A350s.

The size of Airbus’s global workforce also rose by five per cent during the period to 165,294.

Guillaume Faury, Airbus chief executive, said: “2025 was a landmark year, characterised by very strong demand for our products and services across all businesses, a record financial performance, and strategic milestones.

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“We successfully navigated a complex and dynamic operating environment to deliver on our updated guidance.”

Airbus Helicopters’ revenues increased by 13 per cent to €9.bn, with deliveries rising to 392 units – up from 361 in 2024. Revenues at Airbus Defence and Space increased 11 per cent year-on-year to €13.4bn, driven by higher volumes across all business units, Airbus said.

The company’s order intake by value increased to €123.3bn, from €103.5bn a year before, while its consolidated order book value was marginally down at €619bn at the end of 2025 – compared to €629bn in 2024.

Gross commercial aircraft orders totalled 1,000 – up from 878 aircraft a year earlier – with net orders of 889 aircraft after cancellations. The order backlog amounted to a year-end record of 8,754 commercial aircraft at the end of 2025.

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Airbus said the production ramp-up of the A220 was “ongoing” and paced by the integration of Spirit AeroSystems work packages and the balance between supply and demand. It is now targeting a rate of 13 aircraft a month for the A220 programme in 2028.

On the A320 Family, Airbus said US engine maker Pratt & Whitney’s “failure to commit to the number of engines ordered by Airbus” was “negatively impacting” this year’s guidance and the ramp-up trajectory.

The company said as a consequence it now expects to reach a rate of between 70 and 75 aircraft a month by the end of 2027, stabilising at rate 75 after that. It said it continues to target rate five for the A330 programme in 2029 and rate 12 for the A350 programme in 2028.

The company’s board has proposed a full-year dividend of €3.20 per share.

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“Global demand for commercial aircraft underpins our ongoing production ramp-up, which we are managing while facing significant Pratt & Whitney engine shortages,” added Mr Faury.

“The broad and competitive portfolios of Defence and Space as well as Helicopters allow us to capture the momentum in defence. We are also making progress to establish a new global industrial space player, together with our partners.

“These 2025 results and the confidence in our future financial performance support the proposed higher dividend payment.”

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Pubs to open late for home nations World Cup knockout games

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Pubs to open late for home nations  World Cup knockout games

Football fans in the UK will be able to enjoy an extra round at the pub thanks to new rules during the men’s World Cup.

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(VIDEO) Former Prince Andrew Arrested on Suspicion of Misconduct in Public Office

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Andrew Mountbatten-Windsor

Andrew Mountbatten-Windsor, formerly known as Prince Andrew, was arrested Thursday on suspicion of misconduct in public office, Thames Valley Police confirmed, in connection with allegations that he shared confidential trade documents with convicted sex offender Jeffrey Epstein while serving as Britain’s special trade envoy more than a decade ago.

Andrew Mountbatten-Windsor
Andrew Mountbatten-Windsor

The 66-year-old, who resides at Wood Farm on the Sandringham estate in Norfolk, was taken into custody early Thursday morning — coinciding with his birthday — following a police operation involving searches at addresses in Berkshire and Norfolk. Officers executed warrants at the properties as part of an ongoing investigation, Thames Valley Police said in a statement released shortly after 8 a.m. local time.

“We have today (19/2) arrested a man in his sixties from Norfolk on suspicion of misconduct in public office and are carrying out searches at addresses in Berkshire and Norfolk,” the force stated, without naming the suspect as per national guidance on arrests. Mountbatten-Windsor remains in custody while inquiries continue, police added.

The arrest stems from a complaint lodged by the anti-monarchy group Republic, which alleged that Mountbatten-Windsor forwarded sensitive trade reports to Epstein around 2010 during his tenure as the United Kingdom’s special representative for international trade and investment. The role, held from 2001 to 2011, involved promoting British business interests abroad.

Thames Valley Police opened a formal investigation in mid-February after assessing the allegations, which surfaced amid renewed scrutiny following recent revelations in unsealed Epstein-related court documents. Those files, released in batches through late 2025 and early 2026, included references to Mountbatten-Windsor’s interactions with Epstein, though no new criminal charges related to sexual misconduct have been filed in this probe.

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Mountbatten-Windsor, the younger brother of King Charles III, was stripped of his royal titles and military affiliations in 2022 amid fallout from his association with Epstein and a settled civil lawsuit brought by Virginia Giuffre, who accused him of sexual abuse — claims he has always denied. He has not held public royal duties since.

The misconduct in public office charge carries a maximum sentence of life imprisonment under British law, though such cases often involve abuse of position for personal gain or improper disclosure of information. Prosecutors would need to prove he knowingly breached official duties in a way that harmed public trust.

Buckingham Palace has not commented on the arrest. A spokesperson for King Charles III declined to address the matter, citing it as a police investigation. The development is likely to intensify scrutiny on the royal family at a time when King Charles continues recovery from cancer treatment announced in 2024.

Public reaction has been swift and polarized, with social media flooded by commentary ranging from calls for accountability to expressions of sympathy. Anti-monarchy campaigners hailed the move as a step toward ending royal impunity, while supporters questioned the timing and evidence.

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Thames Valley Police emphasized the investigation remains active and urged anyone with information to come forward. No charges have been filed, and Mountbatten-Windsor has not been formally interviewed beyond the initial arrest process.

The case marks an unprecedented legal action against a former senior royal, highlighting ongoing fallout from the Epstein scandal more than a decade after the financier’s 2019 death in custody. Epstein’s network included high-profile figures across politics, business and entertainment, with Mountbatten-Windsor one of the most prominent British connections.

As the investigation proceeds, authorities are expected to review documents, communications and witness statements related to the alleged disclosures. The outcome could have significant implications for Mountbatten-Windsor’s legal and personal standing.

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Bill Gates pulls out of India's AI summit over Epstein files controversy

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Bill Gates pulls out of India's AI summit over Epstein files controversy

The Gates Foundation said the decision was made to “ensure the focus remains on the summit’s key priorities”.

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I-RES 2025 Preliminary Results presentation: Earnings growth and regulatory clarity boost outlook

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I-RES 2025 Preliminary Results presentation: Earnings growth and regulatory clarity boost outlook


I-RES 2025 Preliminary Results presentation: Earnings growth and regulatory clarity boost outlook

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Recommendations System Glitch Blamed for Massive Disruption

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YouTube Agrees to $24.5M Settlement Over Trump Account Suspension

YouTube experienced a widespread global outage on Tuesday evening, Feb. 17, 2026, that left millions of users unable to load videos, access the homepage or use related services like YouTube Music and YouTube Kids, with the company attributing the issue to a problem in its recommendations algorithm.

YouTube Agrees to $24.5M Settlement Over Trump Account Suspension
YouTube

The disruption began around 7:45-8:00 p.m. ET (00:45-01:00 GMT on Feb. 18), with outage tracker Downdetector recording a peak of more than 320,000 user reports in the United States alone and tens of thousands more internationally, including spikes in the United Kingdom, India and other regions. Complaints centered on blank homepages, failure to play videos, app freezes, login issues and error messages like “Something went wrong.”

YouTube’s official TeamYouTube account on X (formerly Twitter) acknowledged the problem shortly after reports surged, stating engineers were investigating. By approximately 9:00 p.m. ET, the company provided more detail on its support page and social channels: “An issue with our recommendations system prevented videos from appearing across surfaces on YouTube (including the homepage, the YouTube app, YouTube Music and YouTube Kids). The homepage is back, but we’re still working on a full fix.”

The recommendations engine — the AI-driven system that suggests personalized videos based on viewing history, search behavior and engagement — malfunctioned, causing cascading failures across the platform’s front-end interfaces. This prevented content from loading on key surfaces, rendering the service effectively unusable for many despite backend servers remaining operational.

The outage lasted roughly 90-120 minutes in most regions, with partial restoration (homepage functionality returning) by around 9:30-10:00 p.m. ET. YouTube issued a final update around 10:15 p.m. ET: “The issue with our recommendations system has been resolved and all of our platforms (YouTube.com, the YouTube app, YouTube Music, Kids, and TV) are back to normal! We really appreciate you bearing with us while we sorted this out.”

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No widespread reports of the issue persisted into Wednesday, Feb. 18, or Thursday morning, though isolated lingering complaints appeared in some time zones. YouTube did not disclose whether the glitch stemmed from a configuration error, software update deployment failure or other technical root cause, but sources familiar with Google’s operations suggested an incorrect configuration may have been applied too broadly across server clusters in multiple regions, amplifying the impact.

The incident affected YouTube TV subscribers as well, with thousands reporting streaming interruptions and channel access problems. No data loss, security breaches or permanent damage to user accounts were reported.

This marks one of the more significant YouTube outages in recent years, following smaller disruptions in 2025 tied to similar algorithmic tweaks or regional network issues. Google’s vast infrastructure typically provides redundancy, but front-end recommendation dependencies created a single point of failure in this case.

Users in high-traffic areas like the U.S. West Coast (San Francisco, Los Angeles) and India reported the heaviest impacts, consistent with time-zone peaks in evening viewing. Social media erupted with memes and frustration, with many turning to alternatives like TikTok or Twitch during the downtime.

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YouTube, owned by Google (Alphabet Inc.), serves more than 2.5 billion monthly logged-in users and remains the dominant video platform globally. The company emphasized rapid resolution and thanked users for patience, but the event renewed discussions about over-reliance on complex AI recommendation systems and the need for better failover mechanisms.

No compensation or official apologies were announced, though YouTube’s history includes goodwill gestures like ad credits for prolonged creator outages. As services stabilized, normal viewing resumed without apparent long-term effects.

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Nine in 10 high-risk pension funds fail to beat FTSE 100 over five years

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Taxpayers have until 5 April 2025 to make voluntary National Insurance Contributions dating back to 2006 to boost their state pension. Experts advise checking your NI record now.

Nearly nine in 10 higher-risk pension funds have failed to match the performance of the FTSE 100 over the past five years, according to new analysis that raises fresh concerns about retirement outcomes for millions of savers.

Research by Investing Insiders examined almost 13,000 personal and workplace pension funds holding more than £1tn in assets between December 31, 2020 and December 31, 2025. Funds in the medium-high and high-risk categories were benchmarked against the FTSE 100 over the same period.

The FTSE 100 delivered cumulative returns of 84.67 per cent over five years, turning £20,000 into £36,934 and £50,000 into £92,335.

By contrast, 89 per cent of pension funds in the higher-risk categories underperformed that benchmark. Of 7,370 funds analysed at these risk levels, 6,540 failed to keep pace with the index.

The worst-performing fund in the study, Zurich Assurance’s Zurich JPM Emerging Europe Equity Pn ZP GTR in GB, lost 98.59 per cent of its value over five years. A £50,000 investment in that fund would now be worth just £705 — more than £91,000 less than if the same sum had tracked the FTSE 100.

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Other underperformers included funds linked to the collapsed Woodford Equity Income strategy and several UK property-focused vehicles, many of which suffered heavy losses during periods of market stress.

All of the 10 worst-performing funds were categorised as high risk, and 87.6 per cent of the 1,418 funds in that bracket failed to beat the benchmark.

In contrast, the best-performing fund in the study — Aviva Life & Pensions UK’s Aviva Pen Ninety One Global Gold Pn S6 GTR in GB — delivered returns of 180.28 per cent over five years, growing £50,000 to £140,140.

Investing Insiders estimates that the gap between the best and worst performers could equate to a difference of £139,000 on a £50,000 contribution over the same period.

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Antonia Medlicott, founder of Investing Insiders, described the findings as alarming. “Some funds in the same risk category are almost tripling investments, while others are wiping out value,” she said. “Savers often assume their pensions are steadily progressing, but performance can vary dramatically.”

She argued that greater transparency is needed from providers, particularly when funds underperform benchmarks for sustained periods. She also urged individuals to take a more active role in reviewing their pension allocations.

While the FTSE 100 is a widely recognised benchmark, pension portfolios are typically diversified across global equities, bonds and alternative assets. As such, some fund managers argue that direct comparison with a single UK index may not fully reflect investment strategy.

Nevertheless, the scale of underperformance highlighted in the report underscores the impact of asset allocation, fund selection and risk profile on long-term retirement savings.

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With retirement outcomes increasingly dependent on defined-contribution schemes, the findings add weight to calls for better default fund design and clearer communication to help savers avoid significant shortfalls in later life.


Amy Ingham

Amy is a newly qualified journalist specialising in business journalism at Business Matters with responsibility for news content for what is now the UK’s largest print and online source of current business news.

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Earnings call transcript: Eramet SA’s H2 2025 results show revenue decline

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Earnings call transcript: Eramet SA’s H2 2025 results show revenue decline

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Is MCX stock too expensive after doubling money in just 1 year? A CME case study explains it

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Is MCX stock too expensive after doubling money in just 1 year? A CME case study explains it
Shares of Multi Commodity Exchange of India have turned multibagger over the past year, rallying over 100% on the back of an unprecedented surge in bullion prices.

In 2025, silver soared 170%, while gold climbed over 60%. The momentum spilled into 2026, with silver rising more than 70% in the first two months before correcting sharply, tumbling 42% from its January 29 record high of Rs 4.20 lakh. Gold, too, has cooled off, slipping 20% from its peak of Rs 1.93 lakh.

The sharp reversal triggered higher margin requirements aimed at curbing volatility. After nearly a month of turbulence and wide price swings, MCX and NSE withdrew the additional 7% and 3% margins on silver and gold contracts, respectively, starting February 19. The easing provided relief to sentiment, pushing MCX shares up as much as x% on the BSE today.

But after a 113% run-up, the key question is: has the stock run ahead of fundamentals?

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During FY21, when crude oil prices turned negative amid the Covid shock, MCX sharply increased margin requirements on crude futures. The immediate impact was visible in volumes. Average daily turnover (ADTV) in crude futures plunged from Rs 17,200 crore in February 2020 to Rs 3,300 crore in April 2020.


Crude options premium ADTV rose as volatility surged. Premium turnover as a share of notional turnover increased from 2.2% in February 2020 to 3.9% in March 2020 and further to 8.3% in April 2020. Over the next few years, participation structurally shifted towards options. Crude options premium ADTV expanded from around Rs 5.5 crore in FY21 to Rs 2,120 crore in FY25 and about Rs 2,400 crore in FY26-to-date.
Since early February 2026, gold prices have declined roughly 10%, while silver is down about 33%. In response, average margin requirements for silver futures jumped from 15% earlier to 72% in February 2026. For gold futures, margins increased from 10% to 30%. The result has been a sharp contraction in futures activity. Gold futures ADTV fell 41% month-on-month to Rs 33,600 crore in February 2026-to-date, while silver futures ADTV declined 58% to Rs 22,700 crore over the same period.Yet, mirroring the crude episode of 2020, options activity has picked up. Premium turnover as a share of overall turnover in gold and silver options increased in late January and February 2026, indicating a shift in trader preference rather than an outright drop in participation.

Is the multiple really stretched?

The CME (Chicago Mercantile Exchange) is the world’s largest commodity derivatives exchange by open interest. Between 2004 and 2007, CME witnessed exponential growth in volumes, according to ICICI Securities. Options contracts traded rose from 48 million in CY04 to 107 million in CY07. Futures contracts doubled from 211 million to 432 million over the same period.

The surge in activity was accompanied by a sharp re-rating. CME’s trailing P/E multiple expanded from 24.62x in January 2004 to a peak of 49.31x in November 2006. Notably, the stock traded above 40x trailing earnings for 24 months between September 2005 and August 2008.

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Outlook

The domestic brokerage has an Add rating and a target price of Rs 2,780 per share. That implies an upside potential of 19% from current levels. MCX’s futures average daily traded volume (ADTV) stood at Rs 55,800 crore for 9MFY26 and Rs 1,09,700 crore for January FY26-to-date. Based on the current trend, futures ADTV is projected at Rs 66,500 crore in FY26E, rising to Rs 80,000 crore in FY27E and Rs 90,000 crore in FY28E. These estimates imply a run-rate of Rs 98,700 crore in the remaining three months of FY26.

In the options segment, at the prevailing run rate, options premium ADTV is estimated at Rs 6,200 crore in FY26, Rs 8,100 crore in FY27 and Rs 9,500 crore in FY28, implying Rs 9,200 crore in the final quarter of FY26.

Also read | As AI panic grips IT stocks, where are market opportunities for big and small investors?

(Disclaimer: Recommendations, suggestions, views and opinions given by the experts are their own. These do not represent the views of The Economic Times)

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