Connect with us

Business

A10 Networks, Inc. 2025 Q4 – Results – Earnings Call Presentation (NYSE:ATEN) 2026-02-05

Published

on

OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Q4: 2026-02-04 Earnings Summary

EPS of $0.26 beats by $0.02

 | Revenue of $80.36M (8.29% Y/Y) beats by $2.27M

This article was written by

Seeking Alpha’s transcripts team is responsible for the development of all of our transcript-related projects. We currently publish thousands of quarterly earnings calls per quarter on our site and are continuing to grow and expand our coverage. The purpose of this profile is to allow us to share with our readers new transcript-related developments. Thanks, SA Transcripts Team

Advertisement
Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Business

Eddie Bauer parent could file for bankruptcy, potentially close North American stores

Published

on

Eddie Bauer parent could file for bankruptcy, potentially close North American stores

Eddie Bauer stores could be next on the chopping block. 

Catalyst Brands, which owns the license to operate Eddie Bauer stores across North America, is preparing to file for bankruptcy protection, a source close to the matter told Fast Company.

Advertisement

The filing could cause the company to shutter all of its North American stores, the person said. 

Catalyst Brands also oversees Lucky Brand, Aéropostale, Nautica, Brooks Brothers and JCPenney, and has not yet confirmed the details of the filing. WWD reported the potential filing last week, noting that it could happen sometime this month. 

None of the other brands under Catalyst will be affected by the potential filing.

An Eddie Bauer store

Eddie Bauer’s corporate parent, Catalyst Brands, also oversees Lucky Brand, Aéropostale, Nautica, Brooks Brothers and JCPenney. (Getty Images)

The company operates mainly across the U.S. and Canada with about 180 locations. There are 20 international locations, according to reports. 

Advertisement

FOX Business reached out to Catalyst Brands for comment. 

GROCERY STORE EDGES OUT PUBLIX AS AMERICA’S FAVORITE

Catalyst Brands LLC emerged as a new retail holding company in 2025 through a merger between JCPenney and SPARC Group, a multi-brand operator that ran several clothing brands

An Eddie Bauer store is seen on Feb. 3, 2026, in Round Rock, Texas.  (Brandon Bell/Getty Images)

The newly formed company brought together operations, distribution networks, management and several brands under one roof. 

Advertisement

COSTCO TO OPEN NEW WAREHOUSE UNDER AFFORDABLE HOUSING DEVELOPMENT IN SOUTH LOS ANGELES

However, those brands have gone through their own obstacles. Prior to the merger, JCPenney contended with slowing foot traffic and lackluster sales for years, causing it to file for bankruptcy protection at the height of the pandemic. It emerged from bankruptcy in 2020 as a private company after being acquired by Simon Property Group and Brookfield Asset Management Inc. 

An Eddie Bauer store is seen on Feb. 3, 2026, in Round Rock, Texas.  (Brandon Bell/Getty Images)

GET FOX BUSINESS ON THE GO BY CLICKING HERE

JCPenney last year continued to shutter a handful of its stores in recent years as it struggled to keep pace with rapidly changing market conditions.  

Advertisement
Continue Reading

Business

The Ultra-Slim Cordless Stick Vacuum That Actually Fits in a Drawer

Published

on

The Dyson PencilVac

The Dyson PencilVac — launched globally in late 2025 and widely available in the United States since January 2026 — is Dyson’s boldest attempt yet to solve one of the biggest pain points in cordless vacuum ownership: storage. At just 15.4 inches (39 cm) tall when collapsed, with a body no thicker than a large water bottle and weighing only 3.97 lbs (1.8 kg) in stick configuration, the PencilVac is the slimmest, most compact full-power cordless stick vacuum Dyson has ever produced.

After seven weeks of daily use in a 1,200 sq ft urban apartment in the United States (two adults, one medium-sized dog, mix of hardwood floors, low-pile rugs, and area carpets), here is the complete, unbiased, hands-on review of whether the PencilVac is a legitimate breakthrough or merely a clever design gimmick.

Design & Build – The Skinniest Dyson in History

The moment you unbox the PencilVac, the first reaction is disbelief: this cannot possibly be a real Dyson. The main body is a single continuous matte-black or “Prussian Blue” anodized aluminum tube with zero visible seams, buttons, or protruding dust-bin. It looks more like a premium designer walking cane than a vacuum cleaner.

Key physical measurements (US units):

Advertisement
  • Deployed height: 44.1 in (112 cm)
  • Collapsed height: 15.4 in (39 cm)
  • Tube diameter: 1.5 in (38 mm)
  • Weight (stick configuration, no accessories): 3.97 lbs (1.8 kg)
  • Weight (handheld mode): 2.98 lbs (1.35 kg)
  • Dust-bin capacity: 0.4 L (13.5 oz)

The collapsing mechanism is single-button magic. Press the release near the grip and the lower tube slides smoothly inside the upper tube in under two seconds — no twisting, no fragile hinges, no multi-step folding. The action is buttery, precise, and feels built to last decades.

Dyson achieved this radical slimness by relocating the motor, cyclones, and battery into the handle area (branded “HyperSlim Power Core”). The dust bin is a tall, narrow cylinder that sits directly under the grip and empties via a bottom hatch with one push. Because it fills vertically instead of horizontally, the 0.4 L capacity feels more usable than the number suggests — most daily clean-ups in a 1,200 sq ft space required emptying only once.

Battery Life & Charging – Solid Real-World Performance

The PencilVac uses a single 21.6 V, 3,000 mAh lithium-ion pack (same cell chemistry as the V15 Detect but far smaller overall). Dyson’s official runtime claims:

  • Eco mode: up to 42 minutes
  • Medium mode: 28 minutes
  • Boost mode: 8 minutes

In US testing (hardwood + low-pile rugs + area carpets, medium shedding dog, typical household dust + occasional cereal/rice spills):

  • Eco: 37–41 minutes (very close to rated)
  • Medium: 23–26 minutes
  • Boost (spot-cleaning stuck debris): 7–8 minutes

Full charge takes 3.5 hours via the compact wall-mount dock that also holds the three included tools. The battery is non-removable, but Dyson provides a standard 2-year warranty and states the cell should retain at least 80% capacity after 1,000 full cycles.

Power delivery stays impressively consistent; unlike some ultra-light competitors that fade dramatically below 20%, the PencilVac maintains usable suction until the final 8–10% of battery life.

Suction Power & Cleaning Performance

Dyson rates the PencilVac at 115 Air Watts on Boost — a far cry from the 240–262 AW of the V15 Detect or Gen5detect. Yet in everyday cleaning the PencilVac punches well above its spec sheet thanks to:

Advertisement
  • The ultra-narrow “Micro Fluffy Optic” roller head (same soft-roller design as the V15 Detect but 30% slimmer)
  • Only 6 mm ground clearance between roller and floor
  • Highly optimized cyclone airflow inside the pencil-thin tube

Real-world pickup results (same 4×6 ft test area, mixed debris: 50% fine dust/sand, 50% pet hair + small cereal pieces):

  • Hardwood floors (Eco): 96–98% removal in one pass
  • Low-pile rugs / area carpets (Medium): 89–93% removal
  • Stuck-on debris (Boost): 78–85% removal (usually requires 2–3 passes)

Pet hair performance is outstanding. The Micro Fluffy Optic roller features anti-tangle bristles and an integrated self-cleaning hair comb that actively sheds hair into the bin during use. In seven weeks with a medium-haired Australian Shepherd, I never once needed to stop and manually de-hair the brush bar.

Edge and corner cleaning is average — the round, narrow head design means tight 90° corners usually require a second pass or the included crevice tool. It’s not class-leading, but far better than most ultra-slim competitors.

Filtration & Allergen Performance

The PencilVac uses a fully sealed five-stage HEPA filtration system that captures 99.99% of particles down to 0.1 microns — the same standard as the Gen5detect and most Dyson premium models. Exhaust air is noticeably cleaner than almost every sub-$600 cordless stick vacuum sold in the US.

Emptying produces almost zero dust cloud thanks to the bottom-drop hatch that directs debris straight down into the trash. The HEPA filter is fully washable and needs rinsing every 3–6 months depending on usage frequency.

Included Accessories & Storage Solution

Standard US kit includes:

Advertisement
  • PencilVac main body
  • Micro Fluffy Optic cleaner head
  • Motorized mini soft-roller head (excellent for upholstery, stairs, car interiors)
  • Crevice tool
  • Combination dusting/upholstery brush
  • Compact wall-mount charging dock with accessory clips

The dock mounts vertically and protrudes only 4.7 inches (12 cm) from the wall when the PencilVac is collapsed and hung. All accessories except the mini roller head clip directly to the dock or magnetically to the main tube. In a small apartment this is a revelation — the entire cleaning system lives behind a door instead of hogging closet space.

Noise Levels

The PencilVac is one of the quietest Dysons ever tested:

  • Eco: 62–64 dB
  • Medium: 68–71 dB
  • Boost: 76–78 dB

For reference, normal conversation is ~60 dB. You can comfortably vacuum in Eco mode during a Zoom call or while someone is napping in the next room.

US Pricing & Value Proposition (February 2026)

Official MSRP: $569 Launch promotions & current street price (Feb 2026): $499–$529 at major retailers (Amazon, Best Buy, Dyson.com, Target, Walmart).

Compared to current US-market alternatives:

  • Dyson V12 Detect Slim: $639–$709
  • Dyson V15 Detect: $749–$799
  • Dyson Gen5detect: $995–$1,135
  • Shark PowerDetect: $449–$499
  • Samsung Bespoke Jet AI: $899–$999
  • Tineco Pure One S15: $399–$449

The PencilVac sits in a rare sweet spot: significantly less expensive than Dyson’s full-size premium models, yet offering noticeably stronger suction, better filtration, and far superior build quality than most sub-$500 cordless sticks.

Who Should Buy the Dyson PencilVac?

Strong buy if you:

Advertisement
  • Live in a small-to-medium apartment or condo (especially urban US apartments)
  • Hate dragging a bulky cordless out of a cramped closet
  • Want true Dyson suction + HEPA filtration without the Dyson price or weight
  • Have mostly hard floors + low-pile rugs / area carpets
  • Prefer quick daily touch-ups over once-a-week deep cleans
  • Value near-zero storage footprint above everything else

Consider alternatives if you:

  • Have medium-to-thick carpets (look at full-size Dysons or Shark uprights)
  • Need longer runtime on medium power (>40 min)
  • Want laser dust detection (exclusive to V15/Gen5 lines)
  • Have very heavy pet shedding and need a larger dust bin (0.7–0.8 L)

Final Verdict – 2026 Score: 9.1 / 10

The Dyson PencilVac is not designed to replace the V15 Detect or Gen5detect. It solves an entirely different problem: how to deliver real suction, real HEPA filtration, and real usability in the smallest possible package.

After seven weeks as the primary daily vacuum, the PencilVac has fundamentally changed how often and how willingly we clean. The collapsed size means it lives behind the front door instead of in a closet — so we grab it every day instead of postponing until “the weekend.”

Flaws exist: the 0.4 L bin is small (though usable), edge cleaning is average, and the price is still premium. But for millions of urban US households who want powerful, filtered cleaning without sacrificing half their storage space, the Dyson PencilVac is currently the best “daily driver” cordless stick vacuum available in 2026.

If the street price stays in the $499–$529 range, it earns a strong recommendation.

Advertisement
Continue Reading

Business

Vietnam’s rise and Thailand’s inequality problem

Published

on

Vietnam’s rise and Thailand’s inequality problem

The article “Richer, Faster—But for Whom? Vietnam’s rise and Thailand’s inequality problem” examines the divergent economic development paths of Vietnam and Thailand, focusing on the concept of “Pro-Poor Growth” from an institutional economics perspective. It highlights a noticeable shift in Thai public sentiment, from urgency to resignation or even encouragement, regarding Vietnam’s economic progress and its potential to surpass Thailand.

The core argument is that institutions—rules, norms, and governance structures—are crucial in determining who benefits from economic growth, and Gross Domestic Product (GDP) alone is insufficient to measure improvements in quality of life for all segments of society. Pro-Poor Growth is defined as economic growth that disproportionately benefits the poor or significantly reduces poverty.

Vietnam’s Experience: Growth with Redistribution

Vietnam’s success in sustained poverty reduction post-1986 Doi Moi reforms, which transitioned it from a centrally planned to a market-oriented economy, is attributed to its “Growth with Redistribution” strategy. Key factors include:

  • Land Reform and Human Capital: Dismantling collective farming and restoring land-use rights to households, alongside significant investment in human capital through the “Education for All” program to prepare unskilled labor for foreign direct investment (FDI).
  • Structural Economic Shift: A systematic move from agriculture to manufacturing and services, with a strong emphasis on generating employment for unskilled labor and gradual skill upgrading.
  • Spatial Development: Heavy investment in infrastructure, such as achieving 99.9% rural electricity coverage by 2018, and fiscal/administrative decentralization to empower local governments. This approach resulted in average growth rates of 5–7% over decades and continuous poverty reduction, despite global crises, increasing per capita income eighteenfold. However, Vietnam still faces the risk of the middle-income trap, leading to the launch of Doi Moi 2.0 aimed at achieving high-income status by 2045.

Thailand’s Path: Growth without Redistribution

In contrast, Thailand, despite rapid economic expansion in the 1980s, followed a trickle-down economics model, believing wealth would eventually benefit the broader population. This approach has led to low growth and high inequality, explained by several institutional weaknesses:

  • Disconnected Policies: Economic growth policies are often formulated separately from poverty reduction and redistribution measures, leaving structural problems unaddressed.
  • Middle-Income State Characteristics: Reliance on foreign labor and capital, coupled with limited coordination for domestic technological and innovation development, indicating a lack of institutional upgrading.
  • Concentrated State-Business Relations: Particularly after 2014, close cooperation with large conglomerates created a “big brother–small brother” dynamic, concentrating resources and disadvantaging smaller enterprises.
  • Policy Inconsistency: Frequent government changes undermine policy continuity, resulting in short-term poverty relief measures (e.g., cash transfers) driven by immediate political demands rather than fundamental structural reforms.

Rethinking Development: Lessons and Recommendations

While Thailand should not merely emulate Vietnam, its experience offers crucial lessons. Escaping the middle-income trap and addressing inequality requires integrating redistribution into the growth strategy from the outset. The article’s central policy argument is that inclusive development must place those at the bottom of the socioeconomic pyramid at the core of economic policymaking, simultaneously pursuing economic expansion and income redistribution. Examples include designing digital economy and infrastructure investments to provide targeted social protection for the poor and using decentralization to spread prosperity and create local employment.

Vietnam’s success is attributed to policy continuity and institutional design that explicitly integrates the poor into its growth strategy, learning from China and East Asian “miracle” economies that demonstrated sustainable, equitable growth is possible in market economies with outward orientation, macroeconomic stability, and human capital investment. Thailand, therefore, needs to rethink its economic policy design—shifting from treating growth and poverty reduction as separate objectives to creating institutional rules that ensure the benefits of development are broadly and sustainably shared, especially with the poor, while upholding democratic principles.

Advertisement

Source : Richer, Faster—But for Whom? Vietnam’s rise and Thailand’s inequality problem

Continue Reading

Business

Claude and OpenAI Codex Now Live in Public Preview for Copilot Users

Published

on

GitHub Opens Door to Rival AI Agents

GitHub on Feb. 4, 2026, launched public preview access to third-party coding agents from Anthropic and OpenAI, allowing developers with Copilot Pro+ or Copilot Enterprise subscriptions to run Claude and OpenAI Codex directly inside GitHub, GitHub Mobile, and Visual Studio Code — a major step toward a multi-agent ecosystem in the developer workflow.

The integration, announced via the GitHub Blog and changelog, introduces “Agent HQ,” a unified dashboard where users can assign tasks to GitHub’s native Copilot agent or switch to Claude by Anthropic or OpenAI Codex without leaving their repository, pull request, or editor environment. Copilot CLI support is expected soon, completing the cross-platform rollout.

“Context switching equals friction in software development,” the company wrote. “Today, we’re removing some of that friction with the latest updates to Agent HQ which lets you run coding agents from multiple providers directly inside GitHub and your editor, keeping context, history, and review attached to your work.”

The move marks a notable shift for Microsoft-owned GitHub, which has long been synonymous with its Copilot product powered by OpenAI models. By embracing direct competitors, GitHub aims to give developers choice, flexibility, and best-in-class performance for different tasks — from code generation and debugging to architecture planning and documentation.

Advertisement

How Agent HQ Works

Users with eligible subscriptions can now:

  • Create a task in GitHub Issues, Discussions, or directly in the Agent HQ tab.
  • Select from available agents: Copilot (default), Claude (Anthropic), or Codex (OpenAI).
  • Let the chosen agent work asynchronously — generating code, reviewing diffs, proposing pull requests, or commenting on existing PRs.
  • Track progress, switch agents mid-task if needed, and maintain full context across interactions.

Claude leverages Anthropic’s Claude Agent SDK, enabling it to commit code directly and participate in pull-request discussions. Codex, the successor to OpenAI’s original Codex model that powered early Copilot, brings strong reasoning and code-completion capabilities, now hosted natively in GitHub’s environment.

Both third-party agents consume GitHub Actions minutes and are subject to usage-based pricing on top of the Copilot subscription. GitHub Docs confirm support for Anthropic Claude and OpenAI Codex in preview, with clear instructions for setup and usage.

Why This Matters in 2026

The announcement arrives amid rapid evolution in AI-assisted coding. Nearly 50% of engineering teams already use multiple AI assistants, according to GitHub’s internal data and industry surveys. Developers often switch between tools — ChatGPT, Claude.dev, Cursor, Gemini Code Assist — losing context each time.

Agent HQ eliminates that friction by centralizing agents where code lives: repositories, pull requests, and VS Code. Teams can assign Claude for careful reasoning on security-sensitive code, Codex for rapid prototyping, and Copilot for everyday autocompletion — all without copying/pasting or context loss.

Advertisement

Anthropic and OpenAI both endorsed the integration. Anthropic stated: “We’re bringing Claude into GitHub to meet developers where they are. With Agent HQ, Claude can commit code and comment on pull requests, enabling teams to iterate and ship faster and with more confidence.” OpenAI echoed the sentiment, noting Codex’s legacy in inspiring modern AI coding tools and excitement about deeper GitHub collaboration.

Developer Reception and Early Feedback

Early reactions on Reddit (r/GithubCopilot, r/ClaudeAI) and X were largely positive. Users praised the ability to “pick the best agent for the job” without tool-switching. One developer tweeted: “Claude and Codex in GitHub? This is huge — no more context loss when I want Claude’s reasoning but stay in my workflow.”

Some expressed concerns about cost (third-party usage adds to billing) and preview stability. Others noted that while Copilot remains the default, the multi-agent approach could reduce vendor lock-in and encourage competition among providers.

GitHub emphasized that the feature targets Pro+ ($39/user/month) and Enterprise ($99/user/month) tiers, with plans to expand access to lower plans later. Free and individual Copilot users are not yet included.

Advertisement

Broader Industry Context

The integration reflects a maturing AI coding landscape. In 2026, developers routinely combine LLMs for specialized tasks: Claude for long-context reasoning, GPT models for creative generation, Gemini for multimodal code, and Copilot for IDE-native speed.

By hosting rivals natively, GitHub strengthens its platform moat. Rather than compete solely on model quality, it becomes the neutral hub for agent orchestration — similar to how VS Code became the de facto editor by embracing extensions.

The move also signals Microsoft’s pragmatic approach to AI partnerships. Despite heavy investment in OpenAI, Microsoft has integrated Anthropic models into Azure and now GitHub, hedging bets across the leading frontier labs.

Looking Ahead

GitHub hinted at more agents joining Agent HQ soon, including custom user-built agents via the Agent SDK. Copilot CLI integration is “coming soon,” potentially enabling terminal-based multi-agent workflows.

Advertisement

For developers, the update offers immediate value: faster iteration, better task specialization, and reduced context-switching overhead. For the industry, it sets a precedent for open, interoperable AI coding platforms rather than walled gardens.

As the public preview unfolds, real-world usage will determine adoption. Early signs suggest strong interest among enterprise teams and power users already juggling multiple AI tools.

In a year defined by agentic workflows, GitHub’s decision to embrace — rather than fight — rival models could prove one of the smartest strategic moves in developer tools.

Advertisement
Continue Reading

Business

Earnings call transcript: Danske Bank Q4 2025 sees strong profit growth

Published

on


Earnings call transcript: Danske Bank Q4 2025 sees strong profit growth

Continue Reading

Business

Amazon Ring expands AI feature to help locate lost dogs

Published

on

Amazon Ring expands AI feature to help locate lost dogs

Amazon’s Ring is rolling out an AI-powered feature designed to help locate missing dogs by scanning footage from neighborhood security cameras – and it’s now available nationwide, even to people who don’t own the company’s devices.

The expansion opens one of Ring’s core features to non-customers for the first time, effectively broadening the company’s ecosystem beyond hardware owners and positioning it as a wider neighborhood platform rather than just a doorbell and home-security business.

Advertisement

“Before Search Party, the best you could do was drive up and down the neighborhood, shouting your dog’s name in hopes of finding them,” Ring chief inventor Jamie Siminoff said in a statement. He added that the feature allows pet owners to enlist nearby neighbors and cameras to help locate lost animals more quickly.

A golden retriever.

A golden retriever runs around a park.  (Getty Images / Getty Images)

AMAZON TO CUT 16,000 ROLES AS IT LOOKS TO INVEST IN AI, REMOVE ‘BUREAUCRACY’

Ring is also committing $1 million to help equip animal shelters across the U.S. with its camera systems, a move the company says is aimed at helping shelters identify and reunite lost dogs with their owners more efficiently. 

The effort is expected to reach thousands of shelters nationwide, with Ring partnering with organizations including Petco Love and Best Friends Animal Society.

Advertisement
ring camera on door entrance

A doorbell device with a built-in camera made by home security company Ring is seen in Silver Spring, Maryland.  (Chip Somodevilla/Getty Images)

When a dog is reported missing through the Ring app, participating outdoor cameras in the area use AI-powered computer vision to look for animals that resemble the missing pet. If a potential match is detected, the camera owner receives an alert and can choose whether to share the footage with the person searching for their dog.

ring doorbell

Ring’s security app experienced major outages on Wednesday. (Ring.com)

Ring says video sharing remains optional and is handled on a case-by-case basis, allowing camera owners to decide whether to participate while maintaining control over their footage.

CLICK HERE TO GET FOX BUSINESS ON THE GO

Lost pets are among the most common posts on Ring’s Neighbors app. The company says more than 1 million lost or found pet reports were made on the platform last year alone, highlighting the scale of the problem the feature is designed to address.

Advertisement
Continue Reading

Business

SRG, Mondium row over Rio Tinto mine contract dispute

Published

on

SRG, Mondium row over Rio Tinto mine contract dispute

SRG Global has taken an engineering firm backed by Monadelphous and Lycopodium to court over work on a $400 million Rio Tinto contract.

Continue Reading

Business

Social supermarket aims to provide affordable food

Published

on

Social supermarket aims to provide affordable food

The charity’s founder says the supermarket also aims to help users get support from other services.

Continue Reading

Business

US government shows interest in financing Cornish mine project

Published

on

Business Live

Any agreement would be linked to South Crofty providing a supply of tin to the US

Drilling at South Crofty mine

Drilling at South Crofty mine(Image: Cornish Metals)

The company behind a major project to revive a historic Cornish tin mine says it could potentially receive financing support from the US government. Cornish Metals, which floated on AIM in December, announced on Thursday it had received a non-binding letter of interest from the Export-Import Bank of the United States (EXIM) – the country’s official export credit agency.

Cornish Metals is looking to reopen South Crofty – a tin and copper mine near the village of Pool. The mine operated for more than 400 years but was shut in 1998 due to lack of investment and falling metal prices. Cornish Metals acquired the mine in 2016 and said last year it was optimistic that commercial extraction could begin by mid-2028.

It is understood the letter of interest outlines EXIM’s capacity to consider up to US$225m in financing. South Crofty may also qualify for special consideration under the agency’s China and Transformational Exports Program, Cornish Metals said.

Potential financing support is linked to South Crofty providing a “responsible supply” of tin concentrate to the US, to build more resilient supply chains.

Advertisement

Don Turvey, chief executive of Cornish Metals, said: “This Letter of Interest from EXIM is a testament to the quality and strategic importance of South Crofty and its potential to become the first new tin producer in the western world.

“This indicative support also demonstrates the ramping up of our discussions with potential project financing sources as we progress towards a final investment decision.

“Against a backdrop of strong tin prices supported by attractive market dynamics and the substantial progress being made on site, we are encouraged by the momentum building across the business as we work towards bringing South Crofty back into production.”

Business Live understands the letter of interest does not constitute a financing commitment.

Advertisement

In December, Cornish Metals said “significant progress” was being made at South Crofty, which is expected to make yearly earnings of £70m once up and running.

The project received the backing of the UK government in 2025 with Chancellor Rachel Reeves committing to invest £29m in the scheme.

Continue Reading

Business

Moderna, Merck report cancer vaccine breakthrough in melanoma trial

Published

on

Moderna, Merck report cancer vaccine breakthrough in melanoma trial

A breakthrough personalized mRNA cancer vaccine that trains the immune system to target patients’ unique tumor mutations is showing promising results. 

Five-year trial data show the risk of recurrence or death in melanoma patients was cut by about half when combined with Merck’s Keytruda, Moderna CEO Stéphane Bancel told FOX Business Wednesday.

Advertisement

“The results are really exciting,” Bancel told FOX Business’ “Mornings with Maria.”

“We saw a recurrence-free survival, meaning people [are] not dying from the disease or getting the disease coming back. At five years, we saw 50% improvement versus people getting Keytruda [alone], Merck’s blockbuster medicine, which has saved so many lives.

COMMON VITAMIN SHOWN TO SLASH SKIN CANCER RISK IN SOME GROUPS, STUDY SUGGESTS

Cancer Vaccine research being performed in a Moderna lab

An assistant conducts cancer vaccine research in the lab at the Moderna Inc. headquarters in Cambridge, Mass., on Tuesday, Mar. 26, 2024.  (Adam Glanzman/Bloomberg via Getty Images)

“As you see, this is very meaningful for patients, and we are very excited because this year we should get the Phase 3 study result for that medicine and, hopefully, if it’s positive, we should be able to file very quickly with the FDA to get this to the American people to save them from their disease.”

Advertisement

Melanoma is considered the deadliest form of skin cancer. The American Cancer Society estimates about 8,500 Americans will die from the disease in 2026.

NUCLEAR WASTE BEING TRANSFORMED INTO PROMISING CANCER TREATMENT AT FORMER MANHATTAN PROJECT SITE

Merck's Kertruda

Keytruda is a prescription medicine used to treat a type of skin cancer called melanoma. (Merck )

Bancel said the individualized approach of intismeran autogene (formerly known as mRNA-4157) allows Moderna to design a custom treatment for each patient based on their specific tumor mutations, enabling the immune system to more precisely target cancer cells.

“If you and I were diagnosed the same day by the same doctor with skin cancer, Moderna would make a different medicine for your cancer and a different medicine for mine,” he told anchor Maria Bartiromo, adding the personalized vaccine can be manufactured in roughly 30 days.

Advertisement

Bancel said the treatment showed no added safety risks or side effects compared with Keytruda alone.

GET FOX BUSINESS ON THE GO BY CLICKING HERE

“You see a huge benefit for the patients and the families with no downside of side effects, so that’s why it’s also so exciting,” he said.

Advertisement

Beyond melanoma, Moderna’s collaboration with Merck is expanding, with nine ongoing studies examining the personalized mRNA therapy in cancers such as kidney, bladder and gastric cancer, among others.

Continue Reading

Trending

Copyright © 2025