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PAMT CORP: Pain Is Likely To Continue Near-Term (Downgrade)

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Bentley workers 'shocked and angry' at job cuts

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Bentley workers 'shocked and angry' at job cuts

A union says the announcement came as a blow to employees with up to 275 positions at risk.

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Icotyde psoriasis pill from J&J to rival Tremfya Skyrizi IL-23 shots

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Icotyde psoriasis pill from J&J to rival Tremfya Skyrizi IL-23 shots

Signage outside Johnson & Johnson offices in Irvine, California, US, on Friday, Oct. 10, 2025.

Kyle Grillot | Bloomberg | Getty Images

Johnson & Johnson on Wednesday said the U.S. Food and Drug Administration approved its once-daily psoriasis pill, the first oral option to rival best-selling shots.

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The FDA approved the pill, Icotyde, to treat moderate to severe plaque psoriasis, an autoimmune condition that causes rough patches of skin. Patients typically start treatment with topical medications.

If those don’t work, they advance to pills or shots. J&J sees Icotyde becoming the first-line systematic treatment for psoriasis, in between topicals and shots.

Drugmakers have been developing more advanced medicines than standard topicals, turning psoriasis into a highly competitive space. Icotyde targets the same IL-23 receptor as best-selling shots like J&J’s Tremfya and AbbVie‘s Skyrizi, giving patients an oral alternative to some of the most advanced — and most expensive — drugs on the market.

“To be able to to be able to have something that is relatively simple, that offers that level of clearance, trusted safety profile, and in a simple pill, we think is going to be revolutionary,” said Jennifer Taubert, chairman of J&J Innovative Medicine.

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J&J estimates about 8 million people in the U.S. have plaque psoriasis, and that 75% of people don’t advance from topicals to shots because of reasons like fearing needles. Taubert sees Icotyde appealing to those patients.

“We believe having the type of profile that Icotyde has in a simple, once-daily oral pill, we think it’s going to be an absolute game changer for patients,” Taubert said.

J&J hasn’t announced how much Icotyde will cost beyond saying the company will help people pay for the medicine. Rival shots Tremfya and Skyrizi cost around $100,000 a year.

J&J sees peak annual sales of Icotyde exceeding $5 billion once it’s approved for other autoimmune conditions. It’s testing the drug for psoriatic arthritis, ulcerative colitis and Crohn’s disease.

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Shares of J&J slid one-quarter of a percent Wednesday while shares of Skyrizi-maker AbbVie fell more than 4%. Protagonist Therapeutics, a biotech company that developed Icotyde with J&J, was trading about flat.

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Brightstar Lottery stock hits 52-week low at 12.6 USD

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Brightstar Lottery stock hits 52-week low at 12.6 USD

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Stocks Can’t Recover While Oil Prices Surge. Why the Fed’s Unlikely to Help.

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Stocks Can’t Recover While Oil Prices Surge. Why the Fed’s Unlikely to Help.

Stocks Can’t Recover While Oil Prices Surge. Why the Fed’s Unlikely to Help.

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US holds interest rates as Iran war triggers oil shock

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US holds interest rates as Iran war triggers oil shock

The US central bank is moving cautiously, despite pressure from the president to cut interest rates.

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Big Tech’s Huge Conglomerate Premium

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Big Tech’s Huge Conglomerate Premium

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Datassential reveals top emerging foodservice chains

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Datassential reveals top emerging foodservice chains

Top chains specialized in focused concepts and tapped into trending flavors.

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Hewlett Packard Enterprise's AI Story Moved To The Network Layer

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Hewlett Packard Enterprise's AI Story Moved To The Network Layer

Hewlett Packard Enterprise's AI Story Moved To The Network Layer

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Iran’s military escalation backfiring, former Israeli general consul says

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Iran's military escalation backfiring, former Israeli general consul says

Iran’s latest military escalation is backfiring on the global stage as new strikes and widening regional fallout expose what a former Israeli consul general in New York called a critical miscalculation by Tehran.

Ambassador Ido Aharoni, who served as consul general of Israel in New York, joined FOX Business’ “Mornings With Maria” on Wednesday to discuss the broader implications of Iran’s recent actions and the shifting dynamics across the Middle East.

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Iran flag in rubble and debris

An Iranian flag lies amid rubble and debris in Tehran. (Atta Kenare/AFP via Getty Images)

“Iran made a terrible mistake attacking Cyprus, thus bringing in the European Union,” Aharoni told host Maria Bartiromo.

He said Iran’s decision to expand its targets is drawing in new international pressure and raising concerns far beyond the region.

IRAN WAR UNLIKELY TO TRIGGER GLOBAL SUPPLY CHAIN CRISIS, GOLDMAN SACHS SAYS

“Iran is presenting a threat to the entire world,” Aharoni said.

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The former consul general argued the U.S. and Israel’s ongoing military campaign is reshaping deterrence and exposing the regime’s vulnerabilities.

“For the first time since 1979, Iran is being punished for its motivation, for its ideology, not just for their actions… This sends a very powerful message throughout the region,” Aharoni said.

“This is how you restore deterrence… This is exactly what is being done.”

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PRINCE REZA PAHLAVI HAS ‘MAJORITY SUPPORT’ AMONG IRANIANS AS PRESSURE BUILDS ON REGIME, CHIEF OF STAFF SAYS

He said Iran’s long-term position is weakening as a result of Operation Epic Fury. 

“They’re not going to be the same regional power that they were before or after this. It will take them decades to rebuild the infrastructure that was destroyed,” Aharoni explained.

Aharoni underscored that Iran’s actions are impacting its own population as instability grows.

“The Iranians are the number one victims of their own regime,” Aharoni said.

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JD Vance vows gas prices will drop as Iran conflict ends

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JD Vance vows gas prices will drop as Iran conflict ends

The Trump administration is working to lower gas prices as motorists continue to pay more at the pump since the outbreak of the Iran war, Vice President JD Vance said Wednesday, noting that the increase is temporary. 

Vance was at the Engineering Design Services, Inc. manufacturing plant in Auburn Hills, Michigan, where he was asked about rising gas prices.

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“Gas prices are up, and we know they’re up,” Vance said. “We know that people are hurting because of it, and we’re doing everything that we can to ensure that they stay lower.”

Vance said prices will eventually start to decline. 

AMERICANS HIT WITH SOARING ELECTRICITY BILLS AS PRICE HIKES OUTPACE INFLATION NATIONWIDE

Vice President JD Vance

 Vice President JD Vance speaks onstage at Engineering Design Services, Inc. on Wednesday in Auburn Hills, Michigan.  (Bill Pugliano/Getty Images / Getty Images)

“The president said this, and I certainly agree with it. This is a temporary blow,” he said. “What happened under the Biden administration is that gas prices were high for four years. Gas prices are higher right now, and frankly, they’re not even as high as they were during certain parts of the Biden administration.”

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Prices have steadily risen following U.S. and Israeli attacks against Iran in recent weeks. 

As of Wednesday, the average price for a regular gallon of gas was $3.84, up from $2.92 a month ago, according to AAA.

GAS PRICES SURGE, PINCHING AMERICANS AND HANDING THE GOP A NEW MIDTERM HEADACHE

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A diesel fuel pump at a Chevron gas station in Seattle, Washington, US, on Monday, March 9, 2026. (M. Scott Brauer/Bloomberg via Getty Images / Getty Images)

In recent weeks, the administration has worked with its allies to release hundreds of millions of barrels of oil from petroleum reserves in an effort to put downward pressure on prices, Vance said. 

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Many U.S. allies are “suffering” much more than many Americans, Vance said. 

“So as much as we’ve got to focus on getting these gas prices down, the reality is, overseas they’re feeling it far worse than we did because we’ve taken the steps to protect our energy economy.”

Once military operations against Iran conclude, prices should decrease to previous levels, said Vance. 

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“We promise that when this conflict draws to a close, when this operation draws to close, we’re going to see those energy prices come back down to reality, because that’s what the president promised to do,” he said. “He delivered an energy-dominant agenda. It’s made us much more secure in the face of these things. But yeah, we’ve got a rough road ahead of us for the next few weeks, but it’s temporary.”

The U.S. produces more oil than any other country, according to the Energy Information Administration (EIA). As of 2023, the latest data available, the U.S. produces 1roughly3 millions barrels per day, followed by Russia and Saudi Arabia.

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