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Welsh spinout firms are not getting the growth capital needed to fly

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The number of Welsh spinouts firms have also fallen shows new research from UK Research and Innovation

John Atack and Simon Ward of Draig Therapeutics.

The new UK Research and Innovation report has revealed what too many Welsh founders already know – we create technology firms but struggle to finance them through the critical early stages. Too few are supported through to serious scale and this is especially true of those spinout businesses that are founded to take university research into the marketplace.

On initial reading, the report shows some good news, with Wales accounting for 3% of UK research income and producing 3.6% of UK university spinouts founded between 2013 and 2024, suggesting we may be punching above our weight in creating companies.

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However, the bad news is that Welsh spinout formation has fallen from around 19 per year in 2013-15 to around seven per year in 2022-24, which means fewer bets, fewer shots on goal, and fewer companies reaching the stage where external capital can realistically back them.

READ MORE: Admiral acquires commercial fleet insurer fintech Flock in an £80m dealREAD MORE: How a £30m Cardiff Capital Region company contract to demolish Aberthaw Power Station was botched

This should worry anyone who cares about productivity, private sector job creation, or building home-grown firms. Indeed, here is where we should all pay attention, because the report’s figures are genuinely alarming.

While Wales generates 3.6% of UK spinouts, it captures only 1.4% of pre-seed and seed equity investment into spinouts, and an astonishing 0.1% of early-stage VC equity investment. In other words, while we create innovative businesses, they just don’t get the finance necessary to scale.

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This is not a small gap but a massive market failure at the exact stage where spinouts transition from “clever science” to commercial execution i.e. building a product, hiring commercial leadership and pricing a serious seed round.

This is the phase where companies either become investable businesses or remain permanently “nearly ready,” and where momentum is either built or lost. If we are capturing virtually none of the early-stage venture capital equity going into spinouts, we are effectively saying they are not a strength of the economy and that Wales, through its Development Bank and other funders, is not properly backing our own potential when it needs it the most.

In fact, the biggest constraint, and one I have been highlighting in this column for two decades, is that Wales simply does not have enough experienced venture capital investors on the ground with the capability and appetite to lead rounds to back winners again and again with only 1.1% of venture capital firms having any office presence here in Wales (and that includes the Development Bank).

If you don’t have lead investors with the necessary expertise, you don’t just get fewer deals, you get weaker syndicates, smaller rounds, slower progress, and a higher risk that firms are pulled towards stronger ecosystems once they show promise. When that happens, Wales loses the long-term value created when a business finally scales.

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Worst still, the report suggests that of the Welsh spinouts founded since 2013 and at least three years old, the majority have failed to raise at all: the worst performance in the UK. In addition, only one in 50 have secured later-stage venture capital rounds above £10m, i.e. a tiny proportion of university-born Welsh firms are reaching the funding thresholds associated with meaningful scale and long-term value creation.

That is scandalous. Those who are part of the funding ecosystem should not try to celebrate spinout formation and then quietly ignore the fact the majority go nowhere because there is insufficient capital being made available.

We know Wales is never going to outspend London, south east England or the east of England on venture capital but that is not the issue.

What is important is whether we can build our own coherent pathway that converts research-led potential into investable ventures and then into scaling businesses that stay and grow here.

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Unfortunately, the evidence suggests we are failing at that test, and it is a shameful performance because it is not inevitable as Wales has universities generating commercialisable research and founders willing to take the leap. And while an outlier, the recent success of Draig Therapeutics, a recent spinout from Cardiff University that has received more than £100m in venture investment, shows the massive potential that exists within our academic institutions.

On the other hand, there have been no real spin-offs from the compound semiconductor sector in South Wales despite it receiving more than £500m of funding from public and private organisations. In addition, one of these funders – the Cardiff Capital Region – has its own £50m investment fund and yet despite operating alongside one of the UK’s most strategically significant deep tech clusters, it has made little impact on turning this investable innovation into businesses that scale.

This is despite the report showing that in the UK, semiconductors are a sector where spinouts dominate and if Wales is going to win in this vital industry, it typically wins through university commercialisation and scale finance which simply isn’t happening.

Therefore, a funding system that includes the Development Bank of Wales, the British Business Bank and the Cardiff Capital Region that cannot get companies from pre-seed to seed, and from seed to meaningful growth, is inadequate at best. At worst, it becomes a machine for producing failure with talented founders wasting time, universities burning credibility, and taxpayers subsidising activity that does not translate into long-term value.

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We need to face the reality caused by those funding Welsh businesses, namely that most Welsh spinouts go nowhere due to a lack of capital. In the absence of any meaningful private venture capital, we need our economic development bodies to build a coherent funding pathway.

Only when we commit resources to doing that properly and create a group of sustainable technology-based scaling firms that create wealth and well-paid jobs in Wales, can anyone claim that our spinouts are a strength and that innovation from our universities are the engine growing the economy.

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Netflix Rival Strikes Deal With Google in Battle for AI Content

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Netflix Rival Strikes Deal With Google in Battle for AI Content

Netflix Rival Strikes Deal With Google in Battle for AI Content

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UK economy unexpectedly stalls in January ahead of energy price surge

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UK economy unexpectedly stalls in January ahead of energy price surge

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Tax office wins $3 million fight with rocks promoter Shane Sadleir

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Tax office wins $3 million fight with rocks promoter Shane Sadleir

The Australian Taxation Office has won a $3 million battle with veteran resources company promoter Shane Beatty Sadleir over bills going back two decades.

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Dow Falls to Lowest Close This Year After Oil’s Latest Climb

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Dow Falls to Lowest Close This Year After Oil’s Latest Climb

The Dow Jones Industrial Average ended Wednesday at its lowest close of the year, dragged down by a new climb in oil prices that threatened to hold fuel costs at painful levels for many U.S. companies and consumers. 

Futures for Brent crude, the global benchmark, rose 4.8% to trade at around $92 a barrel, unbowed by an announcement from the International Energy Agency that its member countries will release a record 400 million barrels of oil from strategic reserves.

Copyright ©2026 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7b1cdeb8

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Mondo Duplantis Smashes Pole Vault World Record Again, Clears 6.31m in Uppsala

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Mondo Duplantis Smashes Pole Vault World Record Again, Clears 6.31m

Swedish athlete Mondo Duplantis continues to dominate the pole vault scene after setting a new world record of 6.31 metres at the Mondo Classic indoor meeting in Uppsala on Thursday.

The Olympic and world champion surpassed his previous mark by one centimeter. Duplantis opened the competition at 5.65m, smoothly progressed through 5.90m and 6.08m, and cleared the historic height with flawless execution.

Flawless Performance and Record-Breaking Consistency

Unlike most track and field disciplines, pole vault has a single world record for indoor and outdoor performances, amplifying the significance of Duplantis’ achievement.

Since setting his first world record in 2020, he has now broken the mark 15 times, according to Reuters. His consistency in breaking records was unbelievable since no athlete has ever done that before.

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The 26-year-old is not only athletic, but his power, timing, and precision are a rare gem in the field. This makes him a once-in-a-generation athlete for the next-gen decade.

International Competitors Push the Field

Norway’s Sondre Guttormsen claimed second place by clearing 6.00m, marking his second successful six-metre vault this season. American vaulters Zachery Bradford and Sam Kendricks, along with Australia’s Kurtis Marschall, all cleared 5.90m, highlighting the growing competitiveness on the international stage.

Despite these strong performances, none could match the technical precision or dominance of Duplantis. According to some fans, it’s not a competition since no one was close to what Duplantis did during that day.

“I always wonder whether he’ll ever jump the highest he possibly can before it’s too late, or if he’ll continue to push it one increment at a time and end up on the back-end of his career before he ever hits his true max height,” one fan said on Reddit.

“Duplantis TLDR: He could’ve made the current WR a long time ago, but he gets a payout every time he breaks it, so he’s been breaking the record by 1cm multiple times a year for a long time,” another one joked.

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Duplantis’ Lasting Legacy in Track and Field

Mondo Duplantis continues to show us that the limits of pole vaulting are only in our heads. He is considered a superhuman by many fans due to his unmatched streak of record-breaking performances.

At each record that he broke, he pushed the boundaries of human performance to the extreme. Some fans believe that pole vaulting should be changed to Mondo vaulting. That’s how good he is when he’s in the zone. He’s unstoppable and is in a league of his own.

Originally published on sportsworldnews.com

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Bitcoin rebounds toward $72K as US Treasury comments ease oil inflation concerns

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Bitcoin rebounds toward $72K as US Treasury comments ease oil inflation concerns
Bitcoin rebounded toward the $72,000 mark after U.S. Treasury Secretary Scott Bessent sought to calm markets over the inflationary fallout of higher oil prices. The cryptocurrency was trading at $71,402 on Friday.

In the past 24 hours, Bitcoin and Ethereum were up 3.03% and 4.37%, respectively. Among major altcoins, BNB, XRP, Solana, Tron, Dogecoin, Cardano, and Hyperliquid gained over 5%.

Vikram Subburaj, CEO of Giottus, said U.S. Treasury Secretary Scott Bessent’s remarks pushed crude about $2 per barrel lower, while Bitcoin rallied to just under $72,000.Subburaj further said that U.S. spot Bitcoin ETFs recorded $115.2 million in net inflows on March 11 and $7.7 million on March 12. The next key macro triggers are the Federal Reserve’s March 17–18 meeting and the U.S. February PPI release on March 18, both of which could influence rate-cut expectations and, by extension, crypto risk appetite.Also Read | Large, mid and small cap mutual funds see rising inflows in February. Is the shift back to equities underway?

The global crypto market capitalisation rose 2.67% to $2.43 trillion, according to CoinMarketCap.
The overall market sentiment remains in the fear zone but has been improving in recent days. The latest rally added more than $50 billion in market value within hours, while the U.S. stock market wiped out nearly $1 trillion, said the CoinDCX Research Team.
In the past week, Bitcoin and Ethereum were up 1.49% and 2.10%, respectively. Among major altcoins, BNB, XRP, Solana, Tron, Dogecoin, Cardano, and Hyperliquid surged up to 23%.
Also Read | Gold and silver ETFs slip up to 3% as rising crude prices dampen rate cut hopes. Is it time to buy or wait?

Technically, Bitcoin is attempting to stabilise above the $70,000 level, which is emerging as a near-term support zone. Overall, the crypto market appears to be in a consolidation phase, where improving institutional participation is gradually counterbalancing macro headwinds such as rising yields, geopolitical tensions, and cautious global risk appetite, said Riya Sehgal, Research Analyst at Delta Exchange.

Market perspective

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Akshat Siddhant, Lead Quant Analyst, Mudrex:

Bitcoin is testing resistance at $72,000 while maintaining bullish momentum. U.S. initial jobless claims came broadly in line with expectations, helping ease macro concerns and support risk assets.

CoinSwitch Markets Desk:

BTC moved close to $71K after U.S. inflation and jobless claims came in line with expectations, but the data offered little new momentum for markets. Traders remain cautious, with futures funding rates around –7%, showing that many participants are still betting on downside.

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Bachem Holding AG 2025 Q4 – Results – Earnings Call Presentation (OTCMKTS:BCHMY) 2026-03-13

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

This article was written by

Seeking Alpha’s transcripts team is responsible for the development of all of our transcript-related projects. We currently publish thousands of quarterly earnings calls per quarter on our site and are continuing to grow and expand our coverage. The purpose of this profile is to allow us to share with our readers new transcript-related developments. Thanks, SA Transcripts Team

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Axsome Therapeutics, Inc. (AXSM) Presents at The Citizens Life Sciences Conference 2026 Transcript

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Axsome Therapeutics, Inc. (AXSM) The Citizens Life Sciences Conference 2026 March 10, 2026 4:00 PM EDT

Company Participants

Mark Jacobson – Chief Operating Officer
Nick Pizzie – Chief Financial Officer

Presentation

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Unknown Analyst

So thank you for joining us again this afternoon at the Life Sciences — Citizens Life Sciences Conference. Excited to be joined next by Axsome. I’m going to turn it over to Mark Jacobson, the Chief Operating Officer, and we’re also joined by CFO, Nick Pizzie. Thank you.

Mark Jacobson
Chief Operating Officer

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Yes. Thanks very much, Jason, and thanks to the Citizens team for having us. And we’ll do this in 2 parts. So Nick and I will run through a brief overview of the company, and then we’ll open it up for Q&A. So thanks again for having us.

And very quickly, of course, we’ve got obligatory forward-looking statements, and we may be making forward-looking statements today. So please review our filings with the Securities and Exchange Commission for a complete summary and overview of the risks and uncertainties associated with our business. Axsome is a commercial and clinical stage biopharmaceutical company. We are focused on central nervous system disorders, in particular, frontiers in central nervous system disorders, and our mission is to develop and deliver transformative medicines for the hundreds of millions of people impacted by CNS conditions.

2025 highlights, Nick, you want to cover those questions?

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Nick Pizzie
Chief Financial Officer

Sure. Yes. 2025 was a successful year for Axsome. We — a couple of milestones that we hit for the year from a sales perspective was Auvelity surpassed over $0.5 billion in revenue. That was only the third year since launch. And total sales for the company were close to $640 million. So super excited. It’s a nice setup for 2026 and how we’re approaching on — and the success that we’ve had in 2025. The

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20 Crew Members Rescued, 3 Still Missing

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Thai Cargo Vessel Targeted in Attack Near Strait of Hormuz

Thai authorities are swiftly coordinating aid following an attack on a Thai cargo ship near the Strait of Hormuz.


THAI CARGO SHIP ATTACK NEAR STRAIT OF HORMUZ: 20 CREW RESCUED, 3 MISSING

Update on Thai Cargo Ship Attacked Near Strait of Hormuz: 20 Crew Rescued, 3 Still Missing

A Thai cargo ship was recently attacked near the strategic Strait of Hormuz, raising security concerns in the crucial maritime corridor. The incident, which occurred under murky circumstances, left the vessel heavily damaged. In the aftermath, international maritime forces quickly responded, highlighting the region’s geopolitical tensions and the risks faced by commercial ships.

Rescue operations have so far successfully saved 20 crew members, who were airlifted to safety. They are currently receiving medical attention and debriefings to piece together the sequence of events. Maritime authorities are collaboratively working to bolster security measures in the area to prevent future incidents of this nature, underscoring the vulnerability of shipping lanes.

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However, the situation remains dire as three crew members are still missing. Search and rescue teams are continuing efforts, scouring the area by sea and air in hopes of locating the missing individuals. The global shipping community watches on, amid rising calls for heightened vigilance and improved safety protocols in international waters.

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Jefferies adds Groww, State Bank of India, 5 others to 23 buy ideas. Here’s the full list

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Jefferies adds Groww, State Bank of India, 5 others to 23 buy ideas. Here’s the full list
International brokerage Jefferies has refreshed its Bottom-up Analyst Top Ideas, adding seven new names to its list of 23 top buys from a coverage universe of 247 stocks. The latest picks span across sectors from banks, auto, steel, and internet. Here’s the full list of new additions.

State Bank of India – The country’s largest bank has a target price of Rs 1,300 and an upside potential of 20% from current market levels. Jefferies says the lender is well placed to grow its loan book, supported by a lower loan-to-deposit ratio (LDR) and stable asset quality. The management is focused on improving return on assets (ROA) beyond the 1–1.1% range, with scope to increase the fee-to-asset ratio from 0.5% in FY25. A key priority will be to accelerate deposit growth from the current 9% to around 11–12% over the next 12–18 months to support sustainable credit expansion.

Groww – Billionbrains Garage Ventures, the parent company of Groww, has a target of Rs 195 per share, an upside of 23% from the last close. Groww is the largest broker in terms of active clients, with a 28% market share, compared with 15% for the second-largest player. This leadership is driven by its strong mutual fund funnel, an easy-to-use UI and UX, and robust word-of-mouth traction. Jefferies forecasts revenue growth of 29% CAGR over FY26–28E, supported by higher product velocity, similar to its US peer Robinhood, and rising client assets as accounts mature, with client assets having grown 6–11x over the past three years.

Star Health & Allied Insurance – Analysts have pegged the target price at Rs 660 per share. That’s an upside potential of 43% from current levels. The company is the leading private health insurer in India, with a dominant presence in the retail health segment and an estimated market share of around 31%, supported by its strong proprietary distribution network. Jefferies also expects the loss ratio to improve as claim frequency stabilises and recent price hikes support higher net earned premiums (NEP). Early signs of this trend are already visible.

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Bharat Forge – The automobile company has a target price of Rs 2,150, translating to an upside of 21% from the current levels. Its operational outlook is showing signs of improvement, supported by indications that the US truck cycle is bottoming out, stronger truck demand in India, easing India–US tariff pressures and continued momentum in the defence segment, says Jefferies. According to Jefferies’ US research team, the strength in orders, along with discussions with OEMs, suggests a meaningful pre-buy trend ahead of the EPA 2027 regulation changes.


JSW Steel – With a target price of Rs 1,400, Jefferies forecasts that the counter can gain nearly 20% from the last close of Rs 1,173 on the BSE. It has rapidly expanded its India capacity from 8 mtpa in FY10 to 34 mtpa in FY25. The company has also announced a 1 mtpa Electric Arc Furnace (EAF)-based expansion in Andhra Pradesh, which is expected to take its India capacity to 43 mtpa by FY29E. Overall, JSTL is targeting an India capacity of 50 mtpa by FY31E. We forecast a healthy 6% CAGR in India volumes over FY26–28E.
Eternal – The company has a target price of Rs 480, a staggering 117% upside from current levels. “Eternal has corrected 32% from its Oct-25 peak and offers good upside from current levels in our view,” the brokerage said. Food delivery remains the key cash generator for Zomato, with the segment continuing to grow at over 15% while profitability improves. The business generates strong returns and cash flows, supported by a duopoly market structure and minimal working capital and capex requirements. Management expects growth to accelerate to around 20% in the medium term. The company also sees a large opportunity in quick commerce. Despite intense competition in the segment, Eternal’s Blinkit continues to report strong growth and is the only player to have reached breakeven. This comes even as existing players continue to post significant losses and new entrants are rapidly scaling up their operations.Max Healthcare – The brokerage has assigned a target price of Rs 1,320, translating to an upside of 29% from current levels. Max Healthcare plans to double its bed capacity over the next three to four years, with most of the expansion coming through brownfield additions, which typically have shorter breakeven periods and higher EBITDA margins. The company’s new Dwarka facility broke even in a record six months and began contributing to EBITDA from 4QFY25, underscoring strong demand in Max’s largest market. Recently acquired facilities in Lucknow and Nagpur have also ramped up well, delivering strong EBITDA growth post-acquisition, while recent bed additions indicate sustained demand. The acquisition of Jaypee’s Noida asset has also scaled up effectively and currently operates at high-teens EBITDA margins.

(Disclaimer: Recommendations, suggestions, views and opinions given by the experts are their own. These do not represent the views of The Economic Times)

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