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Breakthrough cancer treatment ‘could be the cure’ after making ‘death sentence’ tumours ‘disappear’

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Breakthrough cancer treatment 'could be the cure' after making 'death sentence' tumours 'disappear'

A BREAKTHROUGH cancer treatment “could be the cure” for a “death sentence” form of the disease after making tumours disappear.

The experimental approach has seen remarkable success in some brain cancer patients – with experts saying it could be available on the NHS within five years.

Sara Sjölund saw her aggressive brain tumour deactivated after trialling a  breakthrough new treatment

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Sara Sjölund saw her aggressive brain tumour deactivated after trialling a breakthrough new treatment
Dr Paul Mulholland is behind the pioneering brain cancer treatment

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Dr Paul Mulholland is behind the pioneering brain cancer treatmentCredit: Louis Hollingsbee – The Sun
Surgeons looking at magnetic resonance imaging (MRI) brain scans during brain surgery.

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Surgeons looking at magnetic resonance imaging (MRI) brain scans during brain surgery.Credit: Getty

Over 12,000 people are diagnosed with brain tumours every year in the UK.

But just one in 10 patients are alive a decade after their diagnosis, according to Cancer Research UK.

Prognosis tends to be bleak due to how fast brain cancer spreads, as well as a lack of treatments able to successfully combat it.

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But a new treatment plan that combines the drug ipilimumab with surgery, chemotherapy, or radiotherapy, could be a game-changer for many sufferers.

Read more on brain tumours

Ipilimumab – an immunotherapy drug given as a drip into the bloodstream that’s already used on the NHS to treat skin cancer – is first administered to shrink the tumour.

Experts behind the treatment say the drug helps patients’ own immune systems to seek out and destroy cancerous cells.

Patients are then offered surgery to remove what’s left of the tumour, or chemo and radiotherapy – in some cases both.

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So far, only a handful of patients have been offered the innovative new treatment protocol pioneered by Dr Paul Mulholland, a brain cancer specialist at University College London (UCL).

Businesswoman Sara Sjölund became one of them after being diagnosed with brain cancer in 2018 at the age of 38, Mail Online reported.

Sara underwent radiotherapy, chemotherapy and surgery in an effort to halt the spread of her astrocytoma tumour, to no avail.

Sun Health Explainer: What is cancer?

Running out of options by the middle of 2023, Sara was offered the chance to trial the novel brain cancer treatment plan.

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After six months on ipilimumab, Sara’s tumour is “inactive”, according to Dr Mulholland.

“Sara’s scans show remnants of the tumour. As long as it stays as it is she will be fine,” he said.

Sara described it in this way: “Like a dead tree, it is still there but at the moment it does not look like it will regrow.”

Ben Trotman, who was given months to live, saw his aggressive brain cancer effectively disappear

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Ben Trotman, who was given months to live, saw his aggressive brain cancer effectively disappearCredit: Collect
Professor Richard Scolyer was diagnosed with a 'worst of the worst' brain cancer but saw his tumour disappear after treatment

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Professor Richard Scolyer was diagnosed with a ‘worst of the worst’ brain cancer but saw his tumour disappear after treatmentCredit: twitter/@ProfRScolyerMIA

It’s too early to know the outcome of the businesswoman’s treatment, but Sara feels like she’s “been given [her] life back”.

She’s not the first to be offered – and see success from – the breakthrough treatment.

Ben Trotman, 41, who brought forward his own wedding after getting a shock glioblastoma diagnosis and being given “months to live” was left virtually disease-free after being enrolled in a world-first clinical trial for the treatment.

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After “grappling with the fact he had gone from being apparently perfectly healthy to having months to live”, Ben saw his tumour recede in a way that was “previously unheard of”.

Cancer experts have suggested that the immunotherapy drug could in fact become a cure for brain cancer.

Dr Mathew Clement, from the Cancer Research Centre in Wales, told MailOnline: “It is not out of the question that it could be a cure.

“We know ipilimumab is effective for other cancers and we have shown that we can apply them to treat brain tumours.

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“We could see this treatment offered on the NHS within five years.”

The same treatment programme was also used successfully by Prof Richard Scolyer, who was diagnosed with incurable grade 4 glioblastoma cancer after suffering a seizure last year.

‘WORK IN PROGRESS’

Brain cancer is particularly difficult to treat as many drugs can’t bypass the blood brain barrier – a protective wall of cells that acts as a filter and protects the brain from harmful substances and germs in the blood that could cause damage.

But immunotherapy drugs such as ipilimumab don’t encounter this issue, Dr Mulholland said, as they instead work by helping the body’s immune system T-cells to spot and attack tumours.

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Researchers are planning an upcoming clinical trial that will focus on offering the drug as early as possible after patients are diagnosed.

While Sara only received the drug after standard treatment had failed, both Ben and Professor Scolyer were able to use it straight after diagnosis – leading their tumours to disappear.

The most common symptoms of a brain tumour

More than 12,000 Brits are diagnosed with a primary brain tumour every year — of which around half are cancerous — with 5,300 losing their lives.

The disease is the most deadly cancer in children and adults aged under 40, according to the Brain Tumour Charity.

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Brain tumours reduce life expectancies by an average of 27 years, with just 12 per cent of adults surviving five years after diagnosis.

There are two main types, with non-cancerous benign tumours growing more slowly and being less likely to return after treatment.

Cancerous malignant brain tumours can either start in the brain or spread there from elsewhere in the body and are more likely to return.

Brain tumours can cause headachesseizuresnausea, vomiting and memory problems, according to the NHS.

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They can also lead to changes in personality weakness or paralysis on one side of the problem and problems with speech or vision.

The nine most common symptoms are:

  1. Headaches
  2. Seizures
  3. Feeling sick
  4. Being sick
  5. Memory problems
  6. Change in personality
  7. Weakness or paralysis on one side of the body
  8. Vision problems
  9. Speech problems

If you are suffering any of these symptoms, particularly a headache that feels different from the ones you normally get, you should visit your GP.

Source: NHS

As such, giving patients ipilimumab as early as possible may be the key to curing brain cancer, Dr Mulholland claimed.

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“What we want to do is get patients early on in the disease before the body is weakened by chemotherapy and radiotherapy,” he said.

“Essentially we’re saying, let’s protect the immune system so it has the best shot at fighting the cancer.”

Other experts have urged caution on touting the success of the treatment plan, as it’s only been used on a handful of patients.

Dr Matthew Williams, a clinical oncologist at Imperial College London, told MailOnline that we can’t at present know if the drugs could be rolled out at a large scale to treat brain cancer.

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“There are exciting developments but it is very much a work in progress at this stage,” he stated.

It is hoped that the clinical trial set to start next year will provide the data required to see the treatment rolled out on the NHS.

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Womens Workouts

30 Min ALL STANDING CARDIO ABS Workout🔥 | Lose Belly Fat, High Intensity, No Repeat

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30 Min ALL STANDING CARDIO ABS Workout🔥 | Lose Belly Fat, High Intensity, No Repeat



This is a really effective standing abs workout to burn lots of calories and define yous abs. Remember to squeeze your muscle while exercising! Let’s do this! #nojumpingworkout #allstanding

❀Full Body Workout
❀Time: 40 sec on/ 10 sec rest

Calorie Burn 250 – 350 Cal
Warm Up 00:00 – 03:12
Workout 03:12 – 31:35
Cool Down 31:35 – 34:58

*The number of calories you burn will vary from person to person depending on your body composition, workout intensity and also fitness level but this might serve as a guideline.

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DISCLAIMER
If you are new to exercise, you should understand that there is the possibility of physical injury. Please notice that if you performing any exercise or program, you agree that you do so at your own risk. This channel offers health, fitness and nutritional information and is not intended to be a substitute for professional medical advice, diagnosis or treatment.

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Children at greater risk of silent killer after catching Covid, scientists warn – as cases of XEC strain rise

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Children at greater risk of silent killer after catching Covid, scientists warn - as cases of XEC strain rise

KIDS are at risk of developing type 2 diabetes after Covid-19, more so than any other common cold bug.

The findings come as the UK faces a rise in Covid cases, with one in 10 in England and Wales caused by the new XEC strain.

Covid posed a higher risk to children than any other bug when it came to type 2 diabetes developing

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Covid posed a higher risk to children than any other bug when it came to type 2 diabetes developingCredit: Getty

There is no evidence so far the strain is more deadly, but data from the UK Health Security Agency (UKHSA) shows Covid hospital admissions are rising in England.

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Researchers studied more than 600,000 children in the US aged between 10 and 19 years old who had either had Covid-19 or another respiratory infection in the first three years of the pandemic. 

The risk of a new diagnosis of type 2 diabetes was significantly higher in the Covid-19 group from one month after infection.

They had around a 50 per cent higher chance of diagnosis one to three months after infection, jumping to 58 per cent at six months.

Read more on Covid and bugs

The risk doubled in children classed as overweight or obese, according to the findings published in the journal JAMA Network Open. 

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Whether the odds of a new diagnosis persist for longer than six months was not studied by the team at Case Western Reserve University School of Medicine, Ohio.

The researchers said type 2 diabetes was already reported as increasing among children – largely due to the obesity epidemic.

Parents have also anecdotally talked of their suspicions that their children’s brush with Covid let to their type 2 diabetes developing.

Type 2 diabetes is often referred to as a ‘silent killer’ because symptoms – such as going to the toilet more often or feeling tired – can often be assumed as common ailments.

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It does not directly kill those who have it but can lead to conditions such as heart disease and stroke, as well as problems with vision, kidneys, and nerve damage.

Mum with ‘smelling superpower’ sniffed out son’s diabetes after noticing strange stench

More often than not, the condition is triggered by poor lifestyle habits like eating too much unhealthy food or not exercising.

Several research teams have shown that adults face an increased risk of diabetes diagnosis after contracting Covid-19.

For example, Canadian scientists said that those who have had Covid are more likely to develop new-onset type 2 diabetes.

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However, a study of Brits by King’s College London suggested that after three months, the risk declined back to baseline levels. 

Diabetes diagnoses were increased by 81 per cent in acute Covid-19 and remained elevated by 27 per cent from four to 12 weeks after infection, according to findings published in PLOS Medicine.

The researchers couldn’t say whether the short-term increase in risk is directly because of Covid infection or if there were undiagnosed cases among those who had Covid.

It comes as research last week suggested Covid “doubles risk of heart attack, stroke or dying up to three years later”.

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Data from more than 10,000 Brits aged over 50 years revealed the danger is even higher among people with blood types A, B or AB compared to those with type O.

None of the participants were vaccinated at the time of infection because Covid-19 jabs were not yet available.

How can you prevent your child developing type 2 diabetes?

Factors such as ethnicity can increase the risk of type 2 diabetes.

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But living with obesity and overweight is thought to be behind the rising number of children with type 2., says Diabetes UK.

If your child is very overweight, the NHS says there are things you can to help them get to a healthy weight.

This includes upping exercise, keeping portions to child-sized, and eating healthier foods.

Exercise doesn’t need to be any more than playing “it”, riding a bike, swimming or using a playground, so long as they are happy and moving.

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“All children need about 60 minutes of physical activity a day for good health, but it doesn’t need to be all at once,” the NHS says.

Food wise, children should avoid eating too much of the same things that cause weight gain in adults – sweets, chocolate, crisps and cakes.

It’s important that as a parent, you also act as a good role model and try and get the whole family involved, so it doesn’t feel like your child is targeted.

It can be a scary time if your child is diagnosed with diabetes, but doctors will be there to support you.

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Your child will get a treatment plan that you as a parent will be involved with administering – including insulin injections.

You will also have to keep a close eye on your child’s glucose levels to make sure they don’t become dangerously low or high.

On top of this, children with diabetes will need to eat a healthy diet and exercise is considered “incredibly important”, Diabetes UK says.

Symptoms of type 2 diabetes in children

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The most common symptoms of type 1 and 2 diabetes in children are:

  • Toilet — Going to the toilet a lot to pass urine, bed wetting by a previously dry child or heavier nappies in babies. Getting up in the night to go to the toilet.  
  • Thirsty — Being really thirsty and not being able to quench the thirst. Your child may ask for a drink more often, finish drinks very quickly or you may notice they generally drink more. 
  • Tired — Feeling more tired than usual. Having less energy than normal, not playing as often, less energy for sports  
  • Thinner — Losing weight or looking thinner than usual.

You may also notice your child getting more infections than usual.

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Risk of bird flu combining with seasonal flu to create mutant strain is 5 times higher – raising ‘pandemic’ fears

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Risk of bird flu combining with seasonal flu to create mutant strain is 5 times higher - raising 'pandemic' fears

THE risk of bird flu merging with seasonal flu to create a dangerous mutant strain is now very high, experts have warned.

They fear the new bug could be as lethal as bird flu and as transmissible as regular flu, giving it the potential to cause a pandemic.

Bird flu could become spreading among people, which might cause major outbreaks,

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Bird flu could become spreading among people, which might cause major outbreaks,Credit: Getty

When two viruses infect someone at the same time, they can mix and create a new, possibly more harmful variant, through a process called reassortment.

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The risk of bird flu reassorting this winter will be five times higher in the winter, compared with the summer, according to preliminary modelling by analytics firm Airfinity.

Bird flu, specifically the H5N1 strain, has been spreading through cattle herds and poultry this year.

At least 17 people have been infected with H5N1 strain in the US this year – almost all of them poultry or dairy workers who had direct contact with sick animals.

Bird flu has a high mortality rate, but currently spreads ineffectively between humans, making it less of a threat.

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But if it were to reassort with a more transmissible flu variant like seasonal flu it could become better at spreading among people, which might cause major outbreaks, experts at the data firm warn.

The likelihood of dairy and poultry workers also being infected with seasonal flu rises in winter, when flu cases rise natually.

Infections always surge in colder months largely due to colder temperatures, indoor crowding, and weakened immune systems. 

On top of this, early data from the US Centre for Disease Control (CDC) suggests the effectiveness of the 2024 flu vaccine to be as low as 35 per cent.

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Coupled with a low uptake of the jab, which would leave more people at risk, these factors raise the likelihood of reassortment taking place, said Connor Browne, a biorisk consultant. 

Map reveals global bird flu hotspots as UK ‘stockpiles vaccines amid fears of a new pandemic’

“The combination of a lower-than-expected efficacy for this year’s flu vaccine and the likelihood that uptake of the vaccine could well be lower than in previous years increases the chances of a H5N1 reassortment event occurring through coinfection,” he said on X, formally Twitter.

Reassortment has been behind most, if not all, historical flu pandemics, including the 2009 ‘swine flu‘ pandemic.

This particualr strain, called H1N1, was a combination of avian, swine, and human influenza viruses, which led to a new variant which was able to spread rapidly.

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It led to the deaths of an estimated quarter of a million people and infected up to 21 per cent of the global population. 

Bird flu is already on the World Health Organisation’s (WHO) list of diseases with pandemic potenital, along with Ebola, Dengue and the black death.

Dr Angela Rasmussen, a virologist at the Vaccine and Infectious Disease Organisation, told a press conference on Thursday that the US needs to focus on “access to testing, getting vaccines to people with high-risk occupational exposure, and answer some of the basic science questions – like how the virus is being transmitted between cows”.

Bird flu: Could it be the next human pandemic?

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By health reporter, Isabel Shaw

BIRD flu is running rampant in wildlife around the world and is now spreading in cows.

This increase in transmission has given the virus lots of opportunities to mutate – a process where a pathogen changes and can become more dangerous.

Scientists fear it’s only a matter of time before one of these mutations makes it better at spreading among mammals – and potentially humans.

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Some experts believe the virus could already be spreading among some animal species.

So far, there is no evidence that H5N1 can spread between humans.

But in the hundreds of cases where humans have been infected through contact with animals over the past 20 years, the mortality rate is high.

From 2003 to 2024, 889 cases and 463 deaths caused by H5N1 have been reported worldwide from 23 countries, according to the World Health Organisation.

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This puts the case fatality rate at 52 per cent.

Leading scientists have already warned an influenza is the pathogen most likely to trigger a new pandemic in the near future.

The prospect of a flu pandemic is alarming.

Although scientists have pointed out that vaccines against many strains, including H5N1, have already been developed, others are still in the pipeline. 

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Mandate training in china #shortvideo #reels #ytshorts #trending #shorts #viralshort #short #video

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Mandate training in china #shortvideo #reels #ytshorts #trending #shorts #viralshort #short #video

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Woman, 31, ‘left to fend for herself’ on A&E trolley for 12 HOURS while coughing blood’ before she died, inquest told

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Woman, 31, ‘left to fend for herself' on A&E trolley for 12 HOURS while coughing blood’ before she died, inquest told

A WOMAN died after she was left “fending for herself” on a hospital trolley in the corridor of an A&E for 12 hours, an inquest has heard.

Tamara Davis, 31, was left coughing up blood and was “abandoned in her most vulnerable moment” when she died of sepsis in December 2022.

Tamara Davis was "left without dignity" before her death

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Tamara Davis was “left without dignity” before her deathCredit: Miya Davis / Brighton Pictures
Miya Davis, Tamara's sister, said she was left to "fend for herself"

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Miya Davis, Tamara’s sister, said she was left to “fend for herself”Credit: Brighton Pictures
Tamsin's boyfriend Raphael Ifil (centre) with her mum Sue and sister Miya outside the court today

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Tamsin’s boyfriend Raphael Ifil (centre) with her mum Sue and sister Miya outside the court todayCredit: Brighton Pictures

She had been rushed to Royal Sussex County Hospital in Brighton after complaining of breathing difficulties.

Tamara was subsequently placed in a side room and given oxygen, but was later moved into a corridor when another patient needed the room.

Despite her condition becoming progressively worse, she was left on a trolley in the busy corridor.

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At one stage there were 20 patients being treated in the hospital corridor.

Eventually a medical team was called and she was rushed through to intensive care, but she later died.

An inquest today heard she had been failed by a healthcare system stretched to the limit.

In a statement read to the court, her sister Miya said: “‘In the few hours [she was in A&E] she was being made to fend for herself.

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“She was abandoned in that corridor at her most vulnerable moments, coughing up blood and suffering from diarrhoea.”

Dr Andrew Leonard, the consultant who treated Tamara in the corridor, said: “Anyone being looked after in a corridor is a concern because it is a failure of normal care processes.”

He said the statements from the family about how they felt Tamara had been failed were “heartbreaking”.

The doctor added: “Unfortunately we live in a world where more corridor care has become increasingly the norm in the last few years and that is a tragedy and not something any doctor or nurse would say is a good idea but is a result of pressures on the system.”

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He said he was “unhappy” Tamara had to receive treatment in a corridor, but added that there was “nowhere else to put patients”.

Tamara had been suffering from cold-like symptoms and breathing difficulties before she collapsed at home on the evening of December 10, 2022.

Her partner Raphael Ifil desperately called 999 five times to try and get an emergency ambulance.

Raphael made a desperate 999 call, but had to rush Tamara to the hospital himself

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Raphael made a desperate 999 call, but had to rush Tamara to the hospital himselfCredit: Brighton Pictures
Tamara with her boyfriend Raphael

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Tamara with her boyfriend RaphaelCredit: Brighton Pictures

But after failing, he got a friend to drive Tamara the three miles to Royal Sussex County Hospital.

She was admitted at 11.14pm and immediately taken through to a resuscitation cubicle in A&E, where she was given oxygen.

But when her vital signs improved and another patient needed the room at 5.30am, she was wheeled out on the trolley into the corridor.

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Tamara then spent the next 12 hours on the trolley with other sick patients all around her, the inquest heard.

She had been diagnosed with severe flu and, although she was given antibiotics, paracetamol and IV fluids, a second dose of antibiotics she was due to receive was missed by medics.

Her condition continued to deteriorate throughout the day and she began to cough up blood and suffered diarrhoea.

Her sister Miya had to help her to the toilet and because there was none available and she had to change her soiled sheets.

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Tamara’s condition continued to worsen throughout the day and she was eventually taken into back into a resuscitation room.

She was then transferred to an intensive care bed, where she was placed on a ventilator.

Alice Edmondson, a senior nurse on duty at the time, said: “We’d never move anyone to a corridor out of choice. Nobody should be nursed in a corridor.

“I really want the family to know that I as a senior nurse feel upset every day that people are in the corridor when they shouldn’t be.”

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Tamara’s condition deteriorated in intensive care and she died of sepsis and multiple organ failure on December 13.

Her heartbroken family have previously said Tamara was “failed” by the hospital and died after ‘disgusting’ treatment.

They say Tamara had been left without “dignity” and said the care she received was “dreadful”.

Previously Dr Andy Heeps, Chief Operating Officer at University Hospitals Sussex NHS Foundation Trust, said: “I cannot publicly discuss Tamara’s care, but in general terms it is undoubtedly the case that our staff sometimes have to work under significant pressure, in difficult circumstances, but they will always do their very best to give care, compassion and dignity to their patients.”

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Tamara and her sister Maya

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Tamara and her sister MayaCredit: Miya Davis / Brighton Pictures 07768 721637***

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Womens Workouts

1000 Calorie Workout – Total Body Weight Loss

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1000 Calorie Workout - Total Body Weight Loss



Want to know how you can burn as much as 1000 calories in one session alone? Here is another 1-hr workout just for you!!

This intensive weight loss workout is an amazing workout that you can do at home to burn fat and strengthen your muscles. This workout is meant to target and burn your fat, even the underlying fat, with continuous workouts.

You can do this workout at least 3-4x a week for the best results. I don’t recommend this to be done everyday but if you can manage to do it, why not! Good luck and let’s get moving!❤️💪

**If you want to be notified when I upload a new video, make sure to subscribe to our channel. I upload new videos everyday from Sunday to Friday!

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