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New cheek test that requires a simple swab could predict how long you’ll live

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New cheek test that requires a simple swab could predict how long you'll live

HOW long someone has left to live can be calculated by taking a simple mouth swab, according to a new study.

Scientists say a “cheeky” discovery allows then to estimate a patient’s risk of dying using cells found in the mouth.

CheekAge can accurately predict the risk of mortality

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CheekAge can accurately predict the risk of mortalityCredit: Alamy

People age at different rates, but several lifestyle factors – including stress, smoking, alcohol, poor sleep, and poor diet – are known to speed up the process.

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Since such environmental effects get “imprinted” on our genome in the form of epigenetic marks, scientists say it is possible to quantify molecular ageing by characterising the epigenome at certain sites.

Over the past decade, scientists have developed several such “epigenetic clocks” calibrated against chronological age and lifestyle factors across large numbers of people.

Most of them focused on DNA methylation in blood cells, which makes collection of samples difficult, as well as stressful for the patient.

Now, American scientists have developed a “second-generation” clock, called CheekAge, which is based on methylation data in easy-to-collect cells from inside the cheeks.

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CheekAge can accurately predict the risk of mortality – even if epigenetic data from another tissue is used, according to the study published in the journal Frontiers in Aging.

Study first author Dr Maxim Shokhirev said: “We also demonstrate that specific methylation sites are especially important for this correlation, revealing potential links between specific genes and processes and human mortality captured by our clock.”

He explained that CheekAge had been developed or ‘trained’ by correlating the fraction of methylation at around 200,000 sites with an overall score for health and lifestyle, reflecting presumed differences in physiological ageing.

Dr Maxim and his colleagues used statistical programming to see how well it predicted death from any cause among 1,513 men and women, born in 1921 and 1936 and followed throughout life by the Lothian Birth Cohorts (LBC) programme of the University of Edinburgh.

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One of the LBC’s aims was to link differences in cognitive ageing to lifestyle and psycho-social factors and biomedical, genetic, epigenetic, and brain imaging data.

Why I am spending millions to be 18 again

Every three years, the volunteers had their methylome in blood cells measured at around 450,000 DNA methylation sites.

The last available methylation time point was used to calculate CheekAge and its association with the risk of dying.

Data on mortality had been obtained from the Scottish National Health Service Central Register.

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Dr Maxim, head of computational biology and data science at the company Tally Health in New York, said: “CheekAge is significantly associated with mortality in a longitudinal dataset and outcompetes first-generation clocks trained in datasets containing blood data.”

He said for every increase by a single standard deviation in CheekAge, the hazard ratio of all-cause mortality increased by 21 per cent – meaning that CheekAge is “strongly associated” with they risk of dying in older adults.

Dr Maxim added: “The fact that our epigenetic clock trained on cheek cells predicts mortality when measuring the methylome in blood cells suggests there are common mortality signals across tissues.

“This implies that a simple, non-invasive cheek swab can be a valuable alternative for studying and tracking the biology of ageing.”

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The researchers looked at those methylation sites which were most strongly associated with mortality in greater detail.

Cheek age could predict ‘healthy lifespan’

Genes located around or near those sites are potential candidates for impacting lifespan or the risk of age-related disease.

For example, the gene PDZRN4, a possible tumour suppressor, and ALPK2, a gene implicated in cancer and heart health in animal models.

Other genes that stood out had previously been implicated in the development of cancer, osteoporosis, inflammation, and metabolic syndrome.

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Dr Adiv Johnson, head of scientific affairs and Education at Tally Health, said: “It would be intriguing to determine if genes like ALPK2 impact lifespan or health in animal models.”

He added: “Future studies are also needed to identify what other associations besides all-cause mortality can be captured with CheekAge.

“For example, other possible associations might include the incidence of various age-related diseases or the duration of ‘healthspan’ – the period of healthy life free of age-related chronic disease and disability.”

Longevity tips from the Blue Zones

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The Blue Zones are five regions across the world where people regularly live to the ripe old age of 100, largely thanks to their diets and daily habits.

The term was coined by author and National Geographic fellow Dan Buettner, who made a name for himself studying the world’s longest living people.

The Blue Zones include Okinawa in Japan, the Nicoya Peninsula in Costa Rica, Ikaria in Greece, Sardinia in Italy and Loma Linda in California.

According to Dan, inhabitants of these swear by nine lifestyle tips.

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Dubbed the ‘Power 9’, the longevity guru argued that they can provide “instructions and clues for how we can set up our lives to live longer”.

They include:

  1. Moving naturally rather than going to the gym
  2. Having a purpose in iife
  3. Keeping stress to minimum with naps and happy hours
  4. Stopping eating before you’re full
  5. Eating mostly plants
  6. Drink no more than two glasses of wine a day and never bingeing
  7. Belonging to a community, faith-based or not
  8. Putting your loved ones first
  9. Keeping a social circle that supports healthy behaviours

Read more on the Power 9 tips here.

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Womens Workouts

Female Booty 🍑 Workout Video 💪🔥🔥 Female Bodybuilder Workout Video At Gym 🙂#shorts #fitnessmodel

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Female Booty 🍑 Workout Video 💪🔥🔥 Female Bodybuilder Workout Video At Gym 🙂#shorts #fitnessmodel

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35-Minute Legs and Glutes Workout | SplitStrong 35 DAY 3 🔥

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35-Minute Legs and Glutes Workout | SplitStrong 35 DAY 3 🔥



SPLITSTRONG 35 DAY THREE: LEGS + GLUTES Workout! 🔥

⭐️ SplitStrong 35 is a FREE 2-Week, Full Body Workout Plan (NEW VIDEOS DAILY)! Download the full calendar here: https://www.nourishmovelove.com/splitstrong-35/

👉🏼 OR find all of the SplitStrong 35 Workouts in this Youtube playlist:

🚨SUBSCRIBE TO MY CHANNEL for more FREE workouts: https://bit.ly/NMLYoutubeSubscribe
💜 Become a member of Team NML (for exclusive workouts, community + accountability): https://www.youtube.com/channel/UCIiI9tAbgvSPPL_50gefFtw/join

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✨THE WORKOUT: 35-Minute Legs and Glute Workout (SplitStrong 35 Day 3)✨

► EQUIPMENT: Medium-to-heavy set of dumbbells. I’m using 15-20 lb dumbbells.
My oversized yoga mat is from Gorilla Mats (affiliate link): http://gorillamats.com?aff=5​​​
*Discount Code: NourishMoveLove

► INSTRUCTIONS:
Follow along with the video above. This lift heavy, Leg Day Workout is all about building lower body strength.

It looks like this:
✔️ 3 Circuits (2-3 dumbbell strength exercises per circuit and 1-2 “burnout” leg exercises per circuit)
✔️ Timed Intervals (40 seconds of work per exercise, 20 seconds rest)
✔️ Repeat Each Circuit x2 Sets
✔️ Workout Includes 5-Minute Mobility Warm-Up and 5-Minute Cool Down Stretching

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►Workout Outline:
1️⃣ CIRCUIT 1: SQUATS
1) 1.5 Goblet Squat
2) Uneven Squat (right first set, left second)
3) Pivot Squat (right first set, left second)
X 2 Sets
🔥BURNOUT
1) Lateral Squat Thruster
2) 5-Second Squat Hold + 1/2 Burpee
X 2 Sets

2️⃣ CIRCUIT 2: DEADLIFTS + LUNGES
1) Deadlift + Calf Raise
2) Reverse Lunge + Calf Raise, Right
3) Reverse Lunge + Calf Raise, Left
X 2 Sets
🔥BURNOUT
1) Alternating Dumbbell Swings
2) Power Lunge Drive to Calf (right first set, left second)
X2

3️⃣ CIRCUIT 3: SUMO SQUATS + LATERAL LUNGES
1) Lateral Lunge (right first set, left second)
2) Sumo Squat
X 2 Sets
🔥 BURNOUT
1) Glute Bridge Frog Pumps

►Find the breakdown of each of these exercises + benefits of training Legs and Glutes in this post: https://www.nourishmovelove.com/splitstrong-35-legs-butt-workout
_________________________________________________________
► TIME STAMPS:
00:00 Workout Introduction
00:48 Warm Up
05:45 CIRCUIT 1: SQUATS
16:20 CIRCUIT 2: DEADLIFTS + LUNGES
27:20 CIRCUIT 3: SUMO SQUATS + LATERAL LUNGES
33:00 Cool Down + Stretch

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**Each video is 35 minutes because I have a dedicated 5 minute mobility routine added to the end of each workout video to improve your form, increase range of motion and keep you injury-free.
_________________________________________________________

►🤰Is this workout Pregnancy/Postpartum Friendly? Yes! Slow down movements as needed. And sub and incline hip thrust for the final exercise in circuit 3.
_________________________________________________________

🚨 SUBSCRIBE to my channel to get notified when NEW WORKOUTS go live! https://bit.ly/NMLYoutubeSubscribe

👉🏼 Find all of the SplitStrong 35 Workouts in this Youtube playlist:

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📅 Download the Workout Calendar PDF and get ALL the details on how to follow this FREE Workout Program here: https://www.nourishmovelove.com/splitstrong-35/

⭐️ FREE WORKOUT PROGRAM: SplitStrong 35⭐️
This plan follows a 5 day workout split, which means you get 5 NEW WORKOUT VIDEOS per week and 2 rest days per week (10 NEW workouts total!). You get to choose when to add your rest days in!

WEEK 1:
▪️Day 1: Legs + Back – https://youtu.be/gsFbHHIbHoQ
▪️DAY 2: Upper Body PUSH (Shoulders, Triceps, Chest + Cardio) – https://youtu.be/7bVaKI0DTgs
▪️DAY 3: Legs + Glutes – 📍You are here!
▪️DAY 4: 15 Minute Power Yoga + Abs – https://youtu.be/N9keRXUIsmc
▪️DAY 5: Dumbbell Abs + Cardio (Core Conditioning #1) – https://youtu.be/MDCf72XJtzo

WEEK 2:
▪️DAY 6: Legs + Chest – https://youtu.be/UHmlhF12kMU
▪️DAY 7: Upper Body PULL (Back, Biceps + Cardio) – https://youtu.be/AA4M_xu0BIk
▪️DAY 8: Unilateral LEGS – https://youtu.be/mM5tnP3Uh2I
▪️DAY 9: 10 Minute Mobility Flow – https://youtu.be/nlH6pyo1nSI
▪️DAY 10: Cardio + Abs with Weights (Core Conditioning #2) – https://youtu.be/DhuM4wYlDfY
_________________________________________________________

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►SUBSCRIBE TO MY EMAIL NEWSLETTER:
Get all of my full length workout videos in your email inbox, and all my insider details (like my favorite athletic gear and more)!

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► Access ALL of my FREE 14-DAY + 30-DAY WORKOUT CHALLENGES: https://www.nourishmovelove.com/category/workouts/move-blog/workout-calendars/

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►FOLLOW On Instagram:
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www.nourishmovelove.com
______________________________________
#legworkout #legsandglutes #lowerbodyworkout

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EP 1|Leg Day at Workouts in My Basement #shortsclip #shorts #shortsfitness #fitness #legdayworkouts

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EP 1|Leg Day at Workouts in My Basement #shortsclip #shorts #shortsfitness #fitness #legdayworkouts

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‘We’re hurtling towards another winter crisis,’ experts warn as NHS figures show A&E is busier than ever

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'We're hurtling towards another winter crisis,' experts warn as NHS figures show A&E is busier than ever

THE NHS is “in bad shape for winter”, experts warn as figures show A&E departments are busier than ever.

The Royal College of Nursing said the health service is “hurtling towards another winter crisis”.

Hospitals and ambulances are always busier in the winter

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Hospitals and ambulances are always busier in the winterCredit: EPA

Hospitals and ambulance services are plunged into difficulty every year and this season is set to bring more of the same.

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Medical director of NHS England, Professor Sir Stephen Powis, admitted it will be “incredibly busy”.

Last year, three in 10 casualty visitors waited more than four hours to be seen and a near-record 54,000 languished for 12 hours or more in January.

NHS statistics showed today that 2.21million people went to A&E last month, the highest ever for September.

It follows the busiest summer on record and comes before winter coughs and colds set in.

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The NHS is approaching winter in bad shape. Patient care continues to fall short of expectations

Siva AnandacivaThe King’s Fund

Ambulance delays and A&E waits have already begun to get worse, the latest data show.

And stats from the UK Health Security Agency show the number of people admitted to hospital with Covid is increasing, from a rate of 3.72 per 100,000 people last week to 4.55 per 100,000.

Siva Anandaciva, of the King’s Fund think-tank, said: “The NHS is approaching winter in bad shape.

Industrial action is continuing, financial pressures are rising, and important performance targets continue to be missed. 

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“Patient care continues to fall short of expectations.”

‘Trade-offs’ between crisis management and reform

Ministers say they are preparing for winter but Health Secretary Wes Streeting has pledged to stop the health service burning cash to cope with daily demands.

Mr Anandaciva added: “NHS services will have to make harsh trade-offs between immediate winter preparations and longer-term improvement.”

Surgery waiting lists remain stubbornly high, rising to 7.64million in August.

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Patricia Marquis, director at the Royal College of Nursing, said: “The NHS appears to be hurtling towards another corridor care crisis this winter. 

“Without intervention, the government’s next 100 days will be defined by patients crammed into fire escapes, store cupboards and corridors.

“The government’s long-term reforms to the NHS are necessary, but patients and nursing staff also need action in the here and now.”

Saffron Cordery, of NHS Providers which represents hospital bosses, said: “The NHS has had its busiest ever summer and is heading for another tough winter.”

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Health minister Karin Smyth said: “We have laid out our plans with NHS England to make sure the system is prepared for winter.”

TIMELINE OF THE NHS WAITING LIST

THE NHS waiting list in England has become a political flashpoint as it has ballooned in recent years, more than doubling in a decade.

The statistics for England count the number of procedures, such as operations and non-surgical treatments, that are due to patients.

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The procedures are known as elective treatment because they are planned and not emergencies. Many are routine ops such as for hip or knee replacements, cataracts or kidney stones, but the numbers also include some cancer treatments.

This is how the wait list has changed over time:

August 2007: 4.19million – The first entry in current records.

December 2009: 2.32million – The smallest waiting list on modern record.

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April 2013: 2.75million – The Conservative and Liberal Democrat coalition restructures the NHS. Current chancellor Jeremy Hunt was Health Secretary.

April 2016: 3.79million – Junior doctors go on strike for the first time in 40 years. Theresa May is elected Prime Minister.

February 2020: 4.57million – The final month before the UK’s first Covid lockdown in March 2020.

July 2021: 5.61million – The end of all legal Covid restrictions in the UK.

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January 2023: 7.21million – New Prime Minister Rishi Sunak pledges to reduce waiting lists within a year, effectively April 2024.

September 2023: 7.77million – The highest figure on record comes during a year hit with strikes by junior doctors, consultants, nurses and ambulance workers.

February 2024: 7.54million – Ministers admit the pledge to cut the backlog has failed.

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Womens Workouts

Day 17 – 30 MIN FULL BODY BURNER HIIT WORKOUT – Full Body, No Equipment, No Repeat

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Day 17 - 30 MIN FULL BODY BURNER HIIT WORKOUT - Full Body, No Equipment, No Repeat



We’re on a roll team! It’s Day 17 of the GROW Challenge and we’ve got another Super Sweaty HIIT Workout to crush together! 30 minutes of full-body, high intensity, fat-burning exercises. Let’s get our heart rate up, push yourself a little extra today – I promise you’ll feel AMAZING! Let’s do it!!

WORKOUT DETAILS

👉🏼 Duration: 30 MINS (Plus 5 mins of cool-down stretches)
👉🏼 Intensity: Super Sweaty 💧💧💧
👉🏼 No Equipment
👉🏼 50 Sec Work, 10 Sec Rest
👉🏼 No Repeat

Please remember that we are all different and that you can make this your OWN workout… take a longer break when you need to.

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Music: https://www.epidemicsound.com

📷 GEAR I USE:
Camera: https://amzn.to/3aticKD
Lens: https://amzn.to/3cCiujR
Tripod: https://amzn.to/2zontX9
Microphone: https://amzn.to/34VaKXH

💪🏼 MY HOME TRAINING GUIDE: http://growingannanas.com

» Subscribe to my Channel for weekly workouts: http://bit.ly/2QLvpXn
» Instagram: http://bit.ly/2ZSdHFR
» Facebook: http://bit.ly/2SVkgpE
✉ Contact (business inquiries): anna@fyndafit.com

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D I S C L A I M E R

If you are a newbie start with a simple and easy exercise before attempting all advanced exercises. Performing exercises out of your capability might strain your muscles and you may get injured.

This channel offers health, fitness and nutritional information. You should not rely on this information as a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment. By performing any fitness exercises without supervision like with this video, you are performing them at your own risk. See a fitness professional to give you advice on your exercise form. Growingannanas will not be responsible or liable for any injury or harm you sustain as a result of this video.

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Urgent call to shut down ‘rogue BBL clinics’ after mum, 33, becomes first in UK to die from dodgy op

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Urgent call to shut down 'rogue BBL clinics' after mum, 33, becomes first in UK to die from dodgy op

SHUT down rogue butt-lift clinics and only let qualified doctors do them, top surgeons have warned.

The Joint Council of Cosmetic Practitioners issued the plea on Thursday after a 33-year-old Brit mum died in September following a botched BBL.

Alice Webb, 33, died in September from complications of a butt-lift procedure

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Alice Webb, 33, died in September from complications of a butt-lift procedureCredit: PA

Brazilian butt-lifts, also known as buttock augmentation procedures, involve injecting fat or filler into the bum to shape it.

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But wrongly injecting too deep into the buttock can pump chemicals into the bloodstream and cause deadly clots, infections or sepsis.

They can also go wrong if the anaesthetic is bungled or people have allergies.

Two people were arrested on suspicion of manslaughter after mum-of-five Alice Webb, from Gloucestershire, died in September following complications of the procedure.

She became the first person to die this way in Britain, although others have suffered fatal ordeals after surgery abroad.

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UK regulation is lax as they can be considered “non-surgical” and untrained beauticians can get the kit to do them.

A lack of regulation for unlicensed medical practitioners puts people’s health at serious risk, particularly with buttock fillers

Elaine SassoonThe British Association of Aesthetic Plastic Surgeons

The JCCP said BBLs must be classified as surgical procedures and strictly controlled so that only qualified, registered and experienced plastic surgeons can do them.

The British Association of Aesthetic Plastic Surgeons, which only recently ended a four-year plea for members not to do the procedure at all, co-signed the report.

The Sun has called on ministers to tighten regulation of fillers and cosmetic procedures in our Had Our Fill campaign.

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Elaine Sassoon, a member of the BAAPS council, said: “The cosmetic sector faces a lack of regulation for unlicensed medical practitioners.

“This puts people’s health at serious risk, particularly with buttock fillers for BBL. 

“While specialist surgeons follow safety guidelines, untrained individuals can inject unsafe, bulk-purchased products in unregulated settings.”

The report said the same rules should be applied to any procedures on the genitals or breasts.

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It said: “These procedures should only be performed by appropriately trained specialist plastic surgeons and fully qualified General Medical Council registered medical doctors who possess additional qualifications and have proven competence.”

Tragic mum told she didn’t need work done

Alice Webb, herself an aesthetic practitioner, had travelled to a training session where she would learn how to perform the procedure before having her own done.

But cops rushed to a house at around 11.30pm that night after the alarm was raised, with ambulances already at the scene.

Alice was taken to Gloucestershire Royal Infirmary but died in the early hours of Tuesday, September 24.

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The tragedy happened after her cousin, Dianna Webb, told her she did not need the procedure.

A GoFundMe page has been started in Alice's honour

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A GoFundMe page has been started in Alice’s honourCredit: Facebook

A tearful Dianna, who calls herself Alice’s “second mum” as she helped raise her, told The Sun: “We had talked about it a lot before she went to have the procedure.

“She had told me she was going to have this done and I said she didn’t need it – she already looked beautiful.

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“And she was stunning on her own.

“We were on the phone for two hours before she went. Alice said they seemed really professional and put her at ease about the procedure.

“She was not one of these people that would go and just have something done without looking at every little detail first, obviously because she worked in the industry too.

“Alice put her heart into her work.

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“She took every course she could take, including this one, because she wanted to make sure she got everything right.”

Dianna said her family would demand the government ban liquid BBL injections to make sure Alice’s death was “the first and the last” on British shores.

A Department of Health spokesperson said: “Our deepest sympathies are with Alice’s family and friends in this tragic case, which is incredibly concerning.

“The safety of patients is paramount, and we would urge anyone considering a cosmetic procedure to consider the possible health impacts and find a reputable, insured, and qualified practitioner.

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“Work is ongoing to explore options around oversight of the non-surgical cosmetics sector and we will provide an update at the earliest opportunity.”

What are Brazilian Bum Lifts and why are they so popular?

Buttock enlargement surgery – known as a Brazilian bum-lift (BBL) – is used to make the bum look bigger, rounded and lifted.

Surgeons transfer fat, inject filler or insert silicone-filled implants.

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It is the fastest growing cosmetic procedure but also one of the most dangerous, according to the British Association of Aesthetic Plastic Surgeons (BAAPS).

Many patients are travelling to the likes of Turkey or seeking out unregistered surgeons in the UK and are not given full information on the risks.

BBLs carry the highest risk of all cosmetic surgeries – with more than one death occurring per 4,000 procedures.

Due to celebrities undergoing such ops, many women are hoping to emulate their looks.

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Consultant clinical psychologist Dr Anu Sayal-Bennett, a chartered member of the British Psychological Society, told the BBC: “Despite there being so much about body positivity, there are pressures for women – and men too – to look a certain way.” 

Many people travel abroad for the procedure because it is cheaper and advertising is “terribly seductive”, combined with the idea of a beach holiday, added Dr Sayal-Bennett.

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