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Sequoia Capital and the evolution of the VC industry

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Sequoia Capital and the evolution of the VC industry

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TABBY KINDER: Sequoia, like a lot of firms in Silicon Valley, is facing this really pivotal, transformational moment.

SEBASTIAN MALLABY: In any downturn, it’s going to be painful for everybody.

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TABBY KINDER: And it’s a really important moment for firms like Sequoia, because they have held this gold standard of VC for so long.

GEORGE HAMMOND: It’s a story about Sequoia, but it’s a story about venture capital. It’s a story about how the industry has grown, and it’s going to have to shrink.

SEBASTIAN MALLABY: When you invest in startups, it’s going to be rock and roll. It’s going to be a bumpy road. It’s not a smooth thing. This is an active, gloves off, combative form of investment.

ORTENCA ALIAJ: Why Sequoia itself is important is because it embodies the VC industry and who Silicon Valley is.

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TABBY KINDER: Sequoia Capital is one of the most venerated venture capital firms in Silicon Valley. It’s 50 years of investing expertise, investing in early stage companies, and betting that some of those companies will become unicorns worth over $1 billion or become even more successful listed companies.

GEORGE HAMMOND: The firm has invested in Apple, Oracle, Cisco, Atari, Google, Yahoo, PayPal, Airbnb, and YouTube, and Instagram, and OpenAI.

BROOKE MASTERS: Companies they backed right now make up 25% of the NASDAQ, which is the tech-heavy index. That just tells you just how crucial they have been to the growth of technology and innovation in the US.

TABBY KINDER: Venture capital is the backbone of the Silicon Valley ecosystem. It’s how companies like Google, like Facebook are founded, essentially.

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ORTENCA ALIAJ: And it has the good sides, which is that it’s fueling this new technology. But there are also the bad sides, not just of Sequoia, but of VC investing, which encourages this sort of fake-it-until-you-make-it attitude amongst entrepreneurs. And that’s where you can have big problems like Sam Bankman-Fried and FTX.

GEORGE HAMMOND: Before artificial intelligence captured the imagination of every investor in Silicon Valley, cryptocurrencies with a major boom and the major area of focus.

LARRY DAVID: Eh, I don’t think so. And I’m never wrong about this stuff. Never.

GEORGE HAMMOND: And Sequoia were not one of the earliest into crypto. They were a little bit sceptical as investors compared to some of their major rivals. Andreessen Horowitz, one of their biggest rivals, really went full speed ahead into crypto– so quite a setback.

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And then when it seemed like crypto was really going up and up and up, they decided to make a big investment into a cryptocurrency exchange called FTX. And they invested $225 million in 2022.

ORTENCA ALIAJ: At the time, Bitcoin was one of the most popular assets. And there was not a clear-cut way for big investment firms to go into cryptocurrency. So once SBF, if I can call him that, came into the scene, that was when people started to legitimise the business. He was seen as this person who was going to institutionalise cryptocurrencies. And, of course, the opposite ended up happening.

TABBY KINDER: The question after FTX failed was, really, how a firm like Sequoia, with so much experience, 50 years of investing expertise, some of the best venture capitalists in the business working at that firm, how they could have got it so wrong and what that says about the diligence done by VC funds over their investments more generally.

REPORTER 1: Venture capital powerhouse Sequoia telling investors this morning that it’s splitting up into three separate and independent partnerships.

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GEORGE HAMMOND: In the last few years, Sequoia has undergone more changes in a shorter amount of time than it has done probably at any other point in its history. Perhaps the most prominent of those was the separation of Sequoia’s US, and European, and Chinese, and Indian businesses.

TABBY KINDER: Sequoia was one of the biggest and boldest entrants to China by a Silicon Valley VC firm. It set up this huge fund. It employed Neil Shen, one of, really, the best start investors in China, to launch its China practise. And for the last couple of decades, it really has had, of all the Silicon Valley firms, the best and largest China presence.

GEORGE HAMMOND: They made the decision to split the firm. It’s a major decision. This was a venture capital firm who was more globally expansive than any other, who was more successful at being globally expansive than any other. They’re retrenching in a very meaningful way.

And, simultaneously, they carved out their Indian operations. And so now what was this massive global business is a US and European-focused entity– so very different in its outlook, in its focus, in its investment area, and a much smaller firm than it was. The Chinese business was managing more than $50 billion in capital.

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And so that is now a distinct entity called Hongshan.

TABBY KINDER: Sequoia US, which is now Sequoia, they own some Chinese companies still. So Sequoia is still an investor in ByteDance, which is a really interesting investment for it, given that TikTok is facing a ban in the US.

BROOKE MASTERS: ByteDance is a really important investment for the firms that are in it because it owns TikTok, which is this wildly successful video site that is incredibly popular with young people, many investors believe is the future, or at least the near future, for advertising and social media. And so if ByteDance is forced to sell TikTok, it’s not clear how that’s going to affect ByteDance’s shareholders.

SEBASTIAN MALLABY: There’s been these series of well-publicised setbacks– ironically, well-publicised because Sequoia is so good. And I would tend to view these setbacks, I’m talking about the FTX investment, I’m talking about having to cut off the China business because of the geopolitics– and I think what determines the future for Sequoia is how skillfully they capture the next technology wave.

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REPORTER 2: The area also supports a variety of light and heavy industries. Investment capital from the city and other parts of the country supports hundreds of pioneering high technology companies in the so-called Silicon Valley, just south of the city.

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GEORGE HAMMOND: Conceptually, it emerged in the 1970s. And it’s called Silicon Valley because of the enormous amount of silicon required to power the semiconductor industry. And it has really been the epicentre of US technology and global technology.

SEBASTIAN MALLABY: In the 1950s and ’60s, Arthur Rock, a financier from New York, showed up in what was then just the Santa Clara Valley, not Silicon Valley, and financed Fairchild Semiconductor, which kickstarted the tech ecosystem on the West Coast. And it was that introduction of risk capital which turned a bunch of disparate engineers into a bunch of people who actually formed a company.

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Right at the beginning of the venture capital story on the West Coast, Arthur Rock set up an office right in San Francisco downtown. But the second wave in the 1970s, Kleiner Perkins, Sequoia, clustered around the Stanford campus, and particularly on Sand Hill Road. And there was a real estate developer at the time who opened up some new office space on Sand Hill Road and made these people welcome. And so it began a tradition.

ILYA A. STREBULAEV: So if I ask you, what are the largest companies that were created in the last 50 years, OK? Well, that would be, you can say Apple and FedEx, OK, all happened just at that point in the 1970s, and it coincided with the rise of the venture capital industry. OK?

And, moreover, I mentioned the ERISA Act, which, effectively, allowed pension fund money and then other money to flow in into riskier assets. And, by the way, from the very beginning, it was not just in Silicon Valley. It was also in Massachusetts.

It was also, at some point, in North Carolina. But Silicon Valley became, very quickly, the hotspot of the venture capital industry.

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SEBASTIAN MALLABY: Of course, it helps in California that non-compete laws could not be enforced. And, therefore, you could pull somebody out of one company, put them into a new company. They would leave one company on a Friday, and on Monday morning, there they are in the new company.

That would have been illegal in Massachusetts. But what differentiated the two was that you had much more aggressive venture capital on the West Coast.

ORTENCA ALIAJ: Sequoia Capital was started in the early-1970s by Don Valentine. He was sort of seen as this very kind of humble person. He is amongst the few who hasn’t named his company after himself.

SEBASTIAN MALLABY: He had been a water polo player and had the physique to go with that. And he’d been a semiconductor salesman as well. And because he’d been on the sales side, he chose to specialise not necessarily in really cutting edge technology, but in the commercialization of existing technology.

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And so, often, the people he backed were kind of crazy business people like Steve Jobs doing Apple, the crew who did Atari, the early game company, that did games like Pong– you walked into their factory, and everyone would get high just from walking around because people were just smoking dope on the production line. These were some pretty wacky founders.

And Atari, for example, would say to their investors, if you want to talk to us, you have to come in this hot tub– take your clothes off and sit in this hot tub. And the good thing about Don Valentine was he wasn’t frightened. And when he took his shirt off, because of that water polo playing I told you about, his authority went up, not down.

And so he was able to look at these crazy founders in the eyes and say, listen, you’re going to take it from me. You’re doing something wrong here. Do it this way, not that way. So he pioneered a hands-on model of venture capital investing, which became central to the model later on.

ORTENCA ALIAJ: Don Valentine had this idea that he didn’t want your classic Harvard Business School graduate to join the firm. He wanted to venture out of that, for want of a better word, and find people who were kind of wonky. And the two people he found who eventually ended up co-leading the firm were, actually, extremely different from each other. So you have Michael Moritz, who’s this Oxford-educated guy who then moves to America to work as a journalist for “Time” magazine.

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SEBASTIAN MALLABY: Don Valentine’s sort of tough guy style of almost boasting about firing company founders, when capital becomes more plentiful, then all the capitalists have to compete to be charming to the startup founders. And threatening them with being fired became a very bad business idea.

And so it’s fitting that Michael Moritz, who had a smoother style, became, basically, the number one after Don Valentine retired. Doug Leone is a slightly different character, much more of a sort of tough guy– again, he once boasted to me that he went to the dentist and had his tooth drilled without anaesthetic just to prove he was tough enough to withstand the pain.

He had an unbelievable work ethic. He was famous for just relentlessly following up, doing calls at 5:00 in the morning, at midnight at night, getting on planes to China the whole time.

GEORGE HAMMOND: Sequoia have managed to have success over generations. Don Valentine founded Sequoia in 1972. He hands over the reins to Mike Moritz and Doug Leone in 1996.

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Roelof Botha joins Sequoia in 2003. He’s hired by Michael Moritz, who at that point is managing partner of Sequoia. And he rises through the ranks. He’s invested in various very successful companies, including YouTube, MongoDB. And he becomes the managing partner of the US and European business in 2017. And in 2022, he steps up to lead the whole firm. This is the global business as was before it split off.

BROOKE MASTERS: Sequoia, like many other great investment firms founded in the 1970s, has been undergoing generational change. Where the founders and the early success stories are getting older. They’re moving on. And they are having to transition to different leadership.

And, in many places, it’s been quite bumpy. It’s complicated. That doesn’t mean they won’t come through with great success. It’s just generational change is awkward.

GEORGE HAMMOND: One incident that brought that to light was a board level conflict at Klarna, which is one of Sequoia’s biggest European investments. It’s a buy now, pay later company. It was once Europe’s most highly valued startup.

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Effectively, what had happened was that Sequoia’s partner on the board, a man called Matthew Miller, had tried to remove Sequoia’s former managing partner, Michael Moritz, who remained as the independent chairman of Klarna– had tried to move against him and have him removed from the board.

TABBY KINDER: Former partner Mike Moritz, one of the biggest veterans investing in Silicon Valley, when he left the firm last summer, he maintained a board seat at Klarna and at many of the other companies where he had led Sequoia’s investments and had become very close to the founders of those companies over time.

ORTENCA ALIAJ: You almost have the physicality of the old guard, the new guard butting heads. And, of course, this spills out into the open. And it also emerges that Matthew Miller did this with the knowledge and backing of Sequoia, which stings even more for Moritz. And, eventually, I think Sequoia see that this has become a public relations disaster. And even though they say, we’ve resolved this, we don’t want to hear any more about it, this becomes another episode, which, I think, starts to make investors feel uncomfortable about what exactly is going on at Sequoia and why this fabled firm is suddenly having these boardroom scraps with former and current employees.

TABBY KINDER: This new generation of venture capitalists at Sequoia have already made some very bold and large bets. Roloff was really fundamental in Sequoia making an investment in Twitter when Elon Musk took it private. And Roloff used to work with Musk at PayPal. They’re very close. Sequoia has other links to Elon Musk.

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GEORGE HAMMOND: That has been part of the reason why Sequoia has invested in multiple of Elon Musk’s ventures, including his tunnel-digging company, the Boring Company, his rockets company, SpaceX, and, more recently, Sequoia put $800 million into Elon Musk’s acquisition of Twitter in 2022.

TABBY KINDER: So far, we just don’t know how successful that investment is going to be. I mean, Twitter is now valued at a fraction of the price that Elon Musk paid for it. What we don’t know is how successful Elon Musk will be in turning Twitter around. And if he can turn it into a successful profit-generating business again, then it will be a rosy investment for Sequoia. But at the moment, it looks very uncertain.

GEORGE HAMMOND: Sequoia struck gold on a number of early investments. So its first investment was Atari, some other very notable investments Apple, Google, these companies which became absolutely huge and, in quite short order, returned huge amounts of money for Sequoia and its own investors. And once it had done that, particularly in the world of venture capital as it was, which was more of a cottage industry 30, 40 years ago, certainly, Sequoia had an incredible brand on which to trade.

And once you have that brand, every start is going to think, right, this is the venture capital firm that I want investment from, because as soon as I have this logo on my company, others are going to think, this is a serious startup, and we should take them seriously.

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YASMEEN BUTT: Right now, we are hosting a tech weekend, which is a three-day event. We do this every five weeks. 200 to 300 founders come over from different states and different countries. The VC mixer idea was that just easy access to VCs in a very short period of time in a location. And we also kept it very transparent. We told people exactly which funds are coming.

NATHAN BECKFORD: So, is it a dream to be funded by the Sequoias of the world? Yes. That’s an easy softball question. Yes, it is. I mean, the credibility that comes from being funded by a Sequoia, or Kleiner Perkins, or Andreessen Horowitz is huge.

It’s a nice stamp of credibility on your vision. It helps you with recruiting. And it helps you with finding co-investors, right? Everyone wants to do a deal with Sequoia, so you’re going to have a lot of other choices and options as a founder if you’ve got Sequoia on your cap table or leading around.

ARMAAN SAINI: I’m not going to lie that everybody’s ideal goal is to get funded by a tier one– Sequoia, Andreessen Horowitz, General Catalyst. And so funds like this, they have deep relationships, pockets, and can really help your business along.

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FARID FADAIE: You need that X factor that helps you grow. That X factor could be the fame of the VC– because if they invest, oh, Sequoia invested in you, there should be something about it. Let’s test it. Because they have a big network, they have a brand recognition– even just them investing in your company will give you a boost.

NATHAN BECKFORD: One of the common themes and common responses I get from founders is, optimise for the best fit with the investor, not necessarily the brand name, or valuation, or terms. You’ve got to find the investor that you can work with and that is going to help you.

And that isn’t always the big brand firms. Some of the newer venture funds are hungry. They’re going to work a little harder, maybe, to build their brands because they’re unproven. And that can be a good choice, too.

So, yes, you still want to take a check from Sequoia if you can. But if they’re not the best fit for you, that’s OK, too.

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GEORGE HAMMOND: When Sequoia was founded, venture capital was really a cottage industry. It was a few dozen firms. In the last 10 or 15 years, the number of venture capital firms in the US has quadrupled. And Silicon Valley has been the epicentre of that, but now Austin, New York, other parts of America also have a real ecosystem. And that has completely changed the nature of the market.

SEBASTIAN MALLABY: If you’re a venture capitalist, it’s much, much bigger than it used to be. And it’s gone global at the same time. So it makes sense that there should be more venture capitalists with more money. But, of course, it’s also possible that there could be too many, that even though the opportunity set has grown, let’s say it’s multiplied by 10, if you multiply the number of venture capitalists by 20, you’ve got a problem.

You’ve got too many investors chasing too few deals. They’re going to bid too hard to get into the deals. They’ll overprice the deals. And then you’ll have a bubble. And we’ve just seen one.

BROOKE MASTERS: There’s been a real shift since 2021 for the venture capital industry. Back then, everyone had money to invest from investors and was just throwing it at companies. Since then, with higher interest rates, investors have become more sceptical about handing their money over to venture capital because they can get good returns with a lot less risk.

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At the same time, the IPO and M&A markets have been largely closed, making it hard to get money out of venture capital and back to investors. So those two things have combined to mean that many venture capital firms have much less money to invest and many less profits to show. So it’s a really challenging time.

TABBY KINDER: Venture capital has, for decades, been a really elite form of investing. And it’s been considered to be quite closed. It’s difficult to get in. Venture capital firms take all of their money from institutional investors like pension funds, university endowment funds.

But in the last few years, there’s been a sort of widening of the industry where big public investors, like, for example, Tiger, SoftBank, come in and create venture capital funds to put money to work in private startup companies.

ORTENCA ALIAJ: I think it’s important to note that Sequoia’s business, the nature of its business, at least, changed with the rise of firms like SoftBank, because you are trying to get a good valuation on the business. And if you have a behemoth like SoftBank just throwing money at these companies at insane valuations, it’s very hard to compete.

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So either you miss out on what could potentially be a good investment because you’re not willing to match that valuation, or you go along with it and you become part of this bubble where the valuations keep getting bid up. And we’ve seen how that’s played out, right? It hasn’t played out great for companies as the interest rate environment has changed.

ILYA A. STREBULAEV: These days, there is more competition, a lot more investors, there is a lot more money at play. Also, it’s easier to enter the market.

Venture capitals nowadays compete both with corporate venture capital funds. They compete with sovereign wealth funds and mutual funds in late stages. They compete with micro VC funds, with angel investors at the early stages. And so this, I think, gives rise to some behaviour that is challenging.

ORTENCA ALIAJ: I think FTX was driven by the FOMO, the fear of missing out, mentality. And at the time, Bitcoin was one of the most popular assets. And there was not a clear-cut way for big investment firms to go into cryptocurrency.

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BROOKE MASTERS: Stories like what happened with FTX, where it turns out to have been a complete fraud, grow out of this environment where every one of the entrepreneurs, or certainly a huge number of them, are overstating what they are going to be able to accomplish. And the venture capitalists kind of bake that in.

It makes them a little bit vulnerable to actual out and out frauds, because they know even the best companies, run by the entrepreneurs who are really smart, probably are slightly overstating. And so their scepticism is built into their model, which is that they don’t expect all of these companies to come good. So they don’t need to actually check that every single one is as legitimate or living up to its claims.

GEORGE HAMMOND: For Sequoia, losing $225 million in the context of their gains elsewhere, is manageable. But reputationally, it was a blow. Because it was Sequoia, because it was this storied 50-year-old firm who didn’t make mistakes, who were very smart, very savvy, and quite cautious, they put their hands up and said, we made a mistake. And they’ve tried to move on from it.

But it coloured their cryptocurrency investment strategy. And I think for some investors in the firm, it was, for the first time in a long time, just a question mark over some of the decision making at Sequoia.

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BROOKE MASTERS: Venture capital investing is a little bit like throwing darts at a dart board. You do not expect all your bets to come good. A successful venture capital firm might back 100 firms, of which only 10 are profitable, and of those 10, one makes it enormous.

But they expect a lot of failure. So it’s built into their model. And so when they back companies, they know that a lot of them aren’t going to come good. They just don’t know which one is going to be the star.

SEBASTIAN MALLABY: There’s a temptation where people say, oh, look, three things went wrong. Three things make a trend. Oh, there must be some systemic crisis here.

But, really, the three things that one could point to are pretty much unconnected, right? There was a geopolitical rift between the US and China, so Sequoia needed to separate the China business from the US business. And that’s just politics. That’s global politics.

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It’s nothing to do with bad investments or whatever. Then, you’ve got a massive crypto bubble in 2022 that bursts, and people across the industry got hit. 20 different venture capital businesses were invested in FTX.

And then, yes, there was a boardroom fight at Klarna. But there are board fights in lots of startups. PayPal was nothing but one big long board fight. And sometimes, actually, the staff were fighting each other, pretty much, with their fists. So it was a mess, but it was still hugely profitable. And when it was sold to eBay, the VCs made a tonne of money.

BROOKE MASTERS: Despite the various bumps in the road, the fact that Sequoia has been able to get $10 billion back to its investors in 2023, which was a very tough year for venture capital, shows that it remains a healthy and thriving firm.

We are at the start of another big investment rush into artificial intelligence. Everybody, including Sequoia, is rushing to find the next big winner out of AI. 60% of Sequoia’s current investments are AI.

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SEBASTIAN MALLABY: Artificial intelligence is at a point where, let’s say, the mobile smartphone ecosystem was around 2007-2008. So the iPhone came out in 2007. The App Store was created in 2008.

WhatsApp and Instagram didn’t come until 2009 and 2010. So it always takes a little while after the new platform is created before you get the new startups that are going to go to more than a $1 dollar valuation based on this new opportunity. And that’s where we are today with AI.

BROOKE MASTERS: And they are hoping that they will, once again, have picked the winner and be riding this train to great success. But there’s also a good chance that a bunch of this money is being wasted. And so if you get lucky and you get the right company, this could be an incredible gusher for investors. It could also be really disappointing.

ORTENCA ALIAJ: Sequoia is still in a strong position. You don’t build up that reputation for, what, five decades, and then all of a sudden three or four mishaps happen and no one cares about you anymore. That’s not the way it works.

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What is interesting to see, and it, honestly, applies across all industries, is how you adapt to the changing interest rate environment and how nimble you can be with geopolitical tensions. And that’s where it really matters.

GEORGE HAMMOND: It’s a story about Sequoia, but it’s a story about venture capital. It’s a story about how the industry has grown, and it’s going to have to shrink. And it’s a story about how you continue to be at the top of your game for 50 years against the backdrop, which is so different to what it was five years ago, 10 years ago, and, certainly, 50 years ago. And it’s a story about whether they can do that under a new management team without the people who were synonymous with that period of huge success for the firm.

BROOKE MASTERS: Overall, I think what the Sequoia story tells you is that the VC industry is under pressure. The way its model used to work is starting to shift. That doesn’t mean it’s fatally wounded, but it is adjusting. And so this is the industry growing up.

TABBY KINDER: Even despite FTX, despite what we’ve seen with Klarna recently, Sequoia still has maintained this sense that it is very much still the best in the business. It’s still the fund that if you are starting a company, you’re desperate for investment for.

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But what we’re seeing with this kind of generational shift, this change in the market, with new investors coming in, new industries to invest in, the potential of AI, for example, being completely unexplored, and we’re yet to see how that plays out, the top dogs of the last 20 years, 10 years from now, could easily be unseated.

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Is there a GLP-1 bubble?

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Good morning. Hurricane Milton is hammering Florida. Conflict in the Middle East is still running hot. Fair to say we have already had several October surprises. Let’s hope CPI, out this morning, is not another. Email us with your fears: robert.armstrong@ft.com and aiden.reiter@ft.com.

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Is there a GLP-1 bubble?

AI gets a lot of attention. There have been thousands of think pieces on how it will transform society, and almost as many arguing that AI hype has driven tech stocks into bubble territory. Glucagon-like peptide-1 (GLP-1) obesity drugs get a lot of attention, too, for their impact on fashion, exercise and health. But almost no one seems to be wondering if there is a GLP bubble.

Eli Lilly and Novo Nordisk, which make the leading GLPs on the market, have wildly outperformed the S&P 500 for the past five years:

Line chart of Normalised returns showing Small waistlines, big returns

Eli Lilly has a price/earnings ratio almost as high as Nvidia’s:

Line chart of 12-month forward P/E estimates ($) showing Expensive pills and chips

Expectations for both companies are really high. Morningstar estimates the GLP-1 drug market will be worth $200bn by 2031, and analysts expect Eli Lilly and Novo Nordisk to take the lion’s share of it. Revenues are expected to nearly triple for Eli Lilly from now until 2031, largely driven by its GLP-1 blockbusters Zepbound and Mounjaro:

Column chart of $bn showing Gilding the Lilly

Novo Nordisk is on a similar trajectory, though Wall Street expects its GLP-1 revenues from Wegovy and Ozempic to start falling after 2029:

Column chart of $bn showing Novo riche

The free cash flow estimates for the two companies are even more astonishing, with both expected to pull in more than $35bn by 2031:

Column chart of Free cash flow $bn showing Printer go brrr

Are expectations set too high? There are several factors to consider.

Competition is fierce. Profitable drugs invite competitors with slightly different formulations or delivery methods. Here is a chart from Morningstar of aspiring GLP-1 market entrants. Novo Nordisk and Eli Lilly may both keep their edge for a while due to their own new products — Novo Nordisk already has an oral drug on the market, though it is not as popular as the injectables, and both companies are set to be first out of the gate on lower-dose oral GLP-1s. But Pfizer and Roche will follow soon after:

Then there are the patents. Novo is set to lose its US patent in 2032, while Eli Lilly is scheduled for 2036 (this partially explains its valuation premium over Novo Nordisk). But importantly for both, Novo Nordisk’s GLP-1 products lose their Chinese patents in 2026, potentially opening the US and European markets to trafficked generics.

The market will begin to discount the patent expirations years before they actually arrive. Shares in AstraZeneca traded sideways for years (at a single-digit price-to-earnings valuation) before the main patents on its blockbusters Nexium and Seroquel expired in the early teens. Pfizer launched its mega-blockbuster Lipitor in 1996. Its revenues peaked at almost $13bn in 2006 and were still about $10bn in 2010, the year before its US patent expired. But the stock had peaked by 2000 and traded at less than 10 times earnings from 2008 to 2011.

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Line chart of Pfizer stock price ($) showing Statin stasis

It is also worth noting, in the context of competition, that while Lipitor was by far the best-selling of the cholesterol-fighting statin drugs, it was the fifth one to launch. Just because Lilly and Novo were the first in GLPs does not mean they will maintain their lead.

Price will also be a question going forward. The GLP-1s face Medicare price negotiations in 2027, and the CBO’s report from this week suggests that Medicare and other insurers may demand significant price reductions.

There is also uncertainty about future volumes. Here is Karen Andersen at Morningstar, one of the few analysts to express scepticism about the buy case for Lilly and Novo:

One of [the big questions] is how long patients will need to stay on therapy. So far from what we have seen, it is difficult to maintain weight loss when patients go off of therapy. Eli Lilly, Novo Nordisk and competitors are thinking of the best way to help patients stay compliant on a maintenance regimen. The answer may be to take the medication less frequently, or at a lower dose . . . That is going to have huge implications for the long-term revenue forecast of these companies, and for the potential health benefits of taking the drugs.

Finally, weight-loss drugs have a rocky history. Some readers may remember the rise and fall of Fen-Phen, or how Sanofi’s much-hyped Acomplia was withdrawn in Europe and never won approval in the US. There have been rumblings about muscle loss and other issues with GLP-1 drugs. As the population of people being treated increases, new issues may emerge.

We don’t know if Lilly and Novo are overvalued. If other drug companies do not develop good alternatives in the next couple of years, no worrisome side effects emerge, most patients are happy to stay on the drugs for the long run, and pricing negotiations go well, the two companies should print money for years to come. What worries us is that no one in the market seems to be taking the bearish side of the GLP-1 trade. In markets, unanimity is dangerous.

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Money

McDonald’s reveals big menu shake up with THREE new items – mozzarella dipper fans will love it

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McDonald’s reveals big menu shake up with THREE new items - mozzarella dipper fans will love it

MCDONALD’S is launching a new menu just in time for Halloween, which will feature new drinks and a side to rival mozzarella dippers.

The fast-food giant is adding three new items next week, The Sun can reveal, and upgrading a breakfast favourite.

Big changes are coming to the McDonald's menu this Halloween

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Big changes are coming to the McDonald’s menu this HalloweenCredit: Getty
McDonald's has launched new Cheese Bites, which cost £2.49 for five

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McDonald’s has launched new Cheese Bites, which cost £2.49 for five

The new and returning items will be landing on menus across the UK and Ireland from October 16.

Among the range is a Toasted Marshmallow Latte, which will be perfect when the nights draw in and the temperature drops.

The latte costs £2.59 but prices may vary depending on the location.

Fans of the Caramel Latte are sure to love this drink, which is blended with toasted marshmallow flavoured syrup.

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It’s topped with whipped cream and a toasted marshmallow flavoured dusting.

Those who don’t like coffee can enjoy the Toasted Marshmallow Hot Chocolate, which has the same syrup, whipped cream and dusting.

The Toasted Marshmallow Latte costs £2.59 while the Toasted Marshmallow Hot Chocolate only comes in a large and costs £2.19.

McDonald’s reveals new breakfast menu item that’s a twist on a classic

Fans of the limited-edition Mozzarella Dippers are also in for a treat as McDonald’s launches new Cheese Bites.

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They come in portions of five for £2.49 or a sharebox of fifteen for £6.79.

Each portion of five Mozzarella and Emmental bites have a smoky caramelised onion flavoured breadcrumb coating.

All Cheese Bites are served with a BBQ Dip.

What’s joining the McDonald’s menu?

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The new Halloween menu items are:

  • Cheese Side – £2.49
  • Cheese Side Sharebox – £6.79
  • Toasted Marshmallow Latte – £2.59
  • Toasted Marshmallow Hot Chocolate (Only available in Large) – £2.19
  • McCrispy® Deluxe – £5.99
  • McCrispy® Deluxe Medium Meal – £7.79
  • Halloween M&M’s® McFlurry® – £2.19
  • Halloween M&M’s® McFlurry® Mini – £1.59
  • Galaxy® Caramel McFlurry® – £2.19
  • Galaxy® Caramel McFlurry® Mini – £1.59
  • Toffee Apple Pie – £1.99
  • Mini Hash Browns Single Portion – £1.49
  • Mini Hash Browns Sharebox – £2.99

Meanwhile, McDonald’s popular Hash Browns are getting an upgrade this season.

The fast-food franchise will start selling mini Hash Browns across its restaurants from next week.

Maccies fans can pick up five for £1.49 or a Sharebox of 15 for £2.99.

Many customers have said the breakfast food reminds them of Tater Tots, which are a popular side in America.

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One social media user posted: “Looks like Tater Tots to me.”

While another added “Otherwise known as a Tater Tot”.

The Sun exclusively got to try them and said they are better than the original.

What is returning to the McDonald’s menu?

Making its return since its debut last autumn is the Toffee Apple Pie.

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The popular crispy pastry will be filled with the same spiced apple compote, toffee sauce and toffee pieces as last year.

Fans of the Toffee Apple Pie will be thrilled that it returns to menus this month

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Fans of the Toffee Apple Pie will be thrilled that it returns to menus this month

It will be available for £1.99 at McDonald’s restaurants.

There are also two McFlurrys returning to menus this month.

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The fan-favourite Halloween M&M’s McFlurry is back and will be topped with Halloween sugar shapes, Galaxy chocolate sauce and M&M’s.

Meanwhile, the Galaxy Caramel McFlurry is also returning and will be swirled with Galaxy Caramel sauce and chocolate pieces.

Both will be available in store for £2.19, or £1.59 for the mini version.

Lovers of the McCrispy will be thrilled to see the McCrispy Deluxe joining menus next week.

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The sourdough style bun will contain a 100% chicken breast fillet in a crispy coating and will be topped with hot and spicy mayo, caramelised onion compose, lettuce, bacon, red onions and a cheddar cheese slice.

It will cost £5.99, or £7.79 for the Medium Meal.

Does McDonald’s often change its menu?

It is not uncommon for McDonald’s to make changes to its menu, which is sold across its 1,400 stores.

Just last week the fast-food chain confirmed that it was bringing back the much-loved McRib burger which had not been seen in the UK for almost a decade.

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Meanwhile, last month saw the return of McDonald’s popular Monopoly game.

To celebrate the launch it added six new items to its menu, including the never-before-seen Twix Latte.

McDonald’s Monopoly 2024

Everything you need to know…

Do you have a money problem that needs sorting? Get in touch by emailing money-sm@news.co.uk.

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Tata’s Gift to India: Ratan’s Philanthropic Journey

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Tata’s Gift to India: Ratan’s Philanthropic Journey

“In our journey of life, we pass pleasures and pain. There will be sunshine and rain; there will be loss and gain. But we must learn to smile again and again.” -RT

Continue reading Tata’s Gift to India: Ratan’s Philanthropic Journey at Business Traveller.

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Business

Taiwan’s president calls on China to ‘live up to’ duty to protect peace

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Taiwan’s President Lai Ching-te has urged Beijing to co-operate with Taipei and the international community to maintain peace and tackle shared challenges as he seeks to build support at home and abroad in the face of Chinese threats.

In his first National Day address since taking office in May, Lai asserted that the People’s Republic of China had “no right to represent Taiwan” but said he was willing to work with China to protect peace and prosperity for people on both sides of the Taiwan Strait.

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“Countries around the world have supported China, invested in China and assisted China in . . . promoting China’s economic development and enhancing its national strength,” Lai said. “This was done out of the hope that China would join the rest of the world in making global contributions . . . and that externally it would maintain peace.”

Making reference to the wars in Ukraine and the Middle East, he added: “We hope that China will live up to the expectations of the international community . . . that it will take up its international responsibilities and, along with Taiwan, contribute to the peace, security and prosperity of the region and the globe.”

Foreign diplomats in Taipei said Lai’s speech was more restrained than his inaugural address, which Beijing called provocative and reacted to with “punishment” exercises. China claims Taiwan as part of its territory and has threatened to annex it with military force if Taipei refuses to submit under its control indefinitely.

China has not previously responded to a Taiwan president’s national address with military moves, and Beijing has not announced new drills. But national security officials in Taiwan and two other democratic countries who wished not to be named said there were indications that the Chinese military was prepared to stage a sequel to the May drills.

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The US urged Beijing to exercise restraint. “There is no justification for a routine annual celebration to be used as a pretext for military exercises,” said a senior US official.

Honour guards in uniform, carrying rifles with bayonets, participate in Taiwan's National Day celebrations in front of the Presidential Office in Taipei
Honour guards in Taiwan’s National Day celebration in Taipei on Thursday © Walid Berrazeg/AFP/Getty Images

Taiwan’s defence ministry said it observed 27 Chinese military aircraft, nine Chinese warships and five other official Chinese vessels participating in joint combat patrols in the vicinity of its waters and airspace in the 24 hours to Thursday morning. Fifteen of the military aircraft entered Taiwan’s air defence identification zone, a self-declared early-warning buffer zone.  

Taiwanese officials said Lai’s speech was meant to be consistent with his inaugural address, in which he promised to “neither yield nor provoke, and maintain the status quo” across the Taiwan Strait.

However, he put a stronger emphasis on the Republic of China, the state founded in China in 1911 following the first Chinese revolution, which was brought to Taiwan by the nationalist Kuomintang after the end of Japanese rule in 1945. The ROC was overthrown in China by the Communist revolution in 1949 but has continued to exist in Taiwan.

Lai hailed the ROC founders’ dream of establishing “a democratic republic . . . a nation of freedom, equality and benevolence”. But he lamented that their project was “engulfed in the raging flames of war” and “eroded under authoritarian rule”, a reference to Taiwan’s decades of military dictatorship under the KMT.

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Taiwanese officials argue that Lai’s focus on the ROC robs Beijing of the opportunity to label him a “Taiwan independence separatist” because it acknowledges the Chinese roots of the state that survives in Taiwan today.

But he also made a strong appeal to his Taiwanese compatriots to unite in defending their de facto independent nation.

“The Republic of China has already put down roots . . . And the Republic of China and the People’s Republic of China are not subordinate to each other,” he said.

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“Regardless of what name we choose to call our nation — the Republic of China, Taiwan or the Republic of China Taiwan — we must all share common convictions. Our determination to defend our national sovereignty remains unchanged.”

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How the EU squandered nearly €11bn of its common budget last year

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This article is an on-site version of our Europe Express newsletter. Premium subscribers can sign up here to get the newsletter delivered every weekday and Saturday morning. Standard subscribers can upgrade to Premium here, or explore all FT newsletters

Good morning. EU interior ministers will today discuss a possible delay to the continent-wide rollout of a new digital border system, on fears that it isn’t yet ready for action, as the FT revealed last month.

Today, our finance correspondent reports on a warning from the EU’s auditor that billions of euros are being misspent, and I explain why Ursula von der Leyen is in Moldova.

Dodgy expenses

Auditors have found that EU funds are increasingly being misspent, just as discussions start on an ambitious overhaul of the bloc’s next common budget, writes Paola Tamma.

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Context: Each year the European Court of Auditors reports on how the EU’s more than €100bn-a-year budget is spent. The vast majority is in payments to member states, for instance to fund infrastructure, regional development projects or agricultural subsidies.

The increased misspending was largely a result of time pressure, the auditors said, as the period for countries to spend certain leftover funds from the previous budget period ended in 2023. In addition, countries have to spend hundreds of billions in post-pandemic recovery funds by 2026.

“Some of it is down purely to the capacity of the body to control expenditure in an orderly fashion, and they’re just overwhelmed,” Tony Murphy, ECA head, told the FT ahead of today’s publication of its yearly budget report.

Last year, nearly €11bn out of €191.2 in budget payouts was misspent, the auditors estimated, including because of accounting errors. That amounts to 5.6 per cent — up from 4.2 per cent in 2022 — continuing an increase over the past three years. Auditors also detected 20 cases of suspected fraud.

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Cohesion funds, which are dedicated to regional development and make up a third of the EU budget, accounted for the bulk of the misspending, with errors up 45 per cent compared with last year.

Auditors also reviewed €53.5bn in post-pandemic recovery payouts, which countries receive once they implement pre-agreed reforms. But auditors found that in 16 out of 452 examined cases, payouts were granted even though the countries hadn’t met the requisite conditions.

That is problematic, especially for those countries that are net receivers of EU funds. The European Commission is planning a budget overhaul that would link all payouts to reforms and pre-agreed investments — much like under the recovery fund — something those countries are wary of.

It also complicates Brussels’ plans to ask net budget contributors, such as Germany, to inject more cash into the next EU budget, due to start in 2028.

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The commission said that it “agrees that improvements are needed, and it is acting accordingly”.

Chart du jour: Dark side

Lukoil’s shadow fleet

An FT investigation has tracked down how Russia built its “dark fleet” of oil tankers, acquiring at least 25 vessels via London and Dubai to evade western sanctions.

Brussels bearhug

European Commission president Ursula von der Leyen will meet Moldova’s Maia Sandu today bearing gifts — and moral support.

Context: Moldova is an EU candidate country and began formal accession talks in June. The country applied for membership in response to Russia’s war against neighbouring Ukraine, a conflict that has imperilled its security and economic stability.

Von der Leyen will use the visit to lay out an EU “growth plan” for Moldova. The initiative, which has already been launched for western Balkan countries, involves increased financial assistance and trade benefits, in exchange for reforms to integrate their economies into the EU’s single market, and prepare them for eventual membership.

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Moldova’s package will be “significant and substantive”, according to a person involved with the preparations.

A Moldovan official said it would “provide the economic leap Moldova urgently needs to overcome the consequences of the war next door, push forward with reforms, and improve the lives of all Moldovans”.

The EU’s economic bear hug isn’t just about economic growth, however. Brussels is also striving to keep Moldova on a pro-EU path, and not see Sandu and her pro-western government toppled by a destabilisation campaign orchestrated and funded by Moscow.

Russia is seeking to influence a double-headed ballot in 10 days time when Moldovans will be asked to choose their next president, and vote in a referendum on enshrining EU membership in its constitution.

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Officials in both Brussels and Chișinău are fearful of either Sandu — who is running for a second term — being replaced by a pro-Russian rival or the referendum failing.

Brussels’ growth plan “will help Moldova become stronger, more resilient, and deeply integrated with Europe as we advance towards EU membership”, the Moldovan official added.

“It will also demonstrate that democracy, even under pressure from Russia, brings real progress and improves lives across the country.”

What to watch today

  1. EU home affairs ministers meet in Luxembourg.

  2. Nato secretary-general Mark Rutte meets UK Prime Minister Sir Keir Starmer in London.

  3. Ukrainian President Volodymyr Zelenskyy travels to London and Paris.

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I refused to believe £111K People’s Postcode Lottery win until key sign told me it was meant to be

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I refused to believe £111K People's Postcode Lottery win until key sign told me it was meant to be

A LUCKY player who scooped a life-changing Postcode Lottery prize refused to believe she had won – until a key sign revealed it was fate.

Sanna Babar, from West Yorkshire, was stunned when she discovered the eye-watering £111,111 windfall after entering the weekly Millionaire Street prize on Monday.

Sanna Babar refused to believe her incredible £111,111 win until a key sign told her it was 'meant to be'

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Sanna Babar refused to believe her incredible £111,111 win until a key sign told her it was ‘meant to be’Credit: People’s Postcode Lottery
The mum-of-two and her husband Tahir revealed their spending plans

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The mum-of-two and her husband Tahir revealed their spending plansCredit: People’s Postcode Lottery

The whopping draw saw nine thrilled neighbours on Shann Crescent, Keighly, share £1million after their postcode BD21 2TN hit the jackpot.

Mum-of-two Sanna told the Postcode Lottery she couldn’t believe her win.

“Wowee! That’s not real. Oh my God, is this real?,” she said.

But she later said it was “meant to be” as her birthday is coming up.

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She added: “I’m going out-out! I was going to go to Bradford, but I think I can go a bit further than that now.”

Her and overjoyed husband Tahir Mehmood are also planning on whisking their family away on a holiday to Disneyland.

Sanna said: “We were thinking of going to Disneyland Paris in August next year, but it could be Florida now!

“I was trying to save up money, but I don’t need to do that now and I could bring my mum and dad too.

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“It was a sort of fantasy before, but I’m going to do it.”

The mum-of-two said how she can’t wait to ring my mum” and spread the incredible news.

Meanwhile, another winner on the street nearly missed out on collecting his £111,000 prize.

Michael Whitaker, from Keighley, had to beg his boss for the day off – and colleagues weren’t impressed.

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The self-confessed adrenaline junkie rang up his boss to ask for the day off so he could be given the huge cheque.

He said: “I rang my boss and told her Postcode Lottery are here. But I had a design and compliance finance meeting at 11am and I had all the figures.

“Luckily, my boss was ecstatic for me and said she wouldn’t tell anyone in the meeting as to why I couldn’t make it.”

Michael hopes to use his jackpot towards a “once-in-a-lifetime” tour around the Norweigan Fjords.

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“When I saw the cheque, I thought £11,000 and then… I processed it and there was six digits! It’s incredible,” he said.

He also dreams of taking his new motorbike, a Triumph Tiger 900, on a road trip.

“I’ve got to an age where I want to see more, and I recently bought the motorbike to go adventure riding.” he said.

He added: “You have dreams but they’re not dreams anymore now. This brings them into reality.”

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The clerk landed the massive cash prize along with eight of his neighbours in Shann Crescent, Keighly, after their postcode BD21 2TN landed the weekly Millionaire Street prize on Monday.

Every cheque was worth £111,111.

How to play the People’s Postcode Lottery?

For just £12 a month, players can sign up through the official website to have a chance of winning millions of pounds.

Once signed up, players are automatically entered into every draw and prizes are announced every day of each month.

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Tickets play for the Daily Prize, worth £1000 and revealed every single day.

Tickets could also win a jackpot of £30,000 for Saturday and Sunday’s Street Prize draws.

People’s Postcode Lottery also offers a £3million Postcode Millions draw each month – where your ticket plays for a share of the cash prize fund.

Winners are notified by email, text, post, or phone call, depending on the prize they win.

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Jackpot winners are visited by the lottery team in person.

It comes as a lucky player doubled their £200,000 Postcode Lottery win by using a clever trick – make sure you don’t miss out.

Jo Deighton from Shoreham, West Sussex, was gobsmacked when she scooped nearly an eye-watering quarter of a million pounds.

Elsewhere, one punter who bagged a £410,000 jackpot told how no one believed her – not even her husband.

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Leyla Eaton’s jaw dropped after discovering she’d scooped the life-changing prize.

The mum-of-two entered when she was struck by a “strong feeling” a huge windfall was coming her way.

Meanwhile, one winning couple who scooped £142,000 in the raffle revealed their plan – but it may surprise you.

The whopping draw saw nine thrilled neighbours on Shann Crescent, Keighly, share £1million after their postcode BD21 2TN hit the jackpot

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The whopping draw saw nine thrilled neighbours on Shann Crescent, Keighly, share £1million after their postcode BD21 2TN hit the jackpotCredit: People’s Postcode Lottery

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