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Dragonfly GP Tom Schmidt Calls Nova Markets Startup 'Huge Scammers,' Slams VCs

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Dragonfly GP Tom Schmidt Calls Nova Markets Startup 'Huge Scammers,' Slams VCs


Tom Schmidt, a general partner at Dragonfly Capital, called Nova Markets "huge scammers" on Thursday, targeting the startup's entire investor cohort in the same post. The accusation came as a quote-tweet of Nova Markets' June 4 fundraise announcement. Dragonfly, which closed a $650 million fourth… Read the full story at The Defiant

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Zcash price plunges 50% amid bug fallout and Hayes selloff, can whales reverse the trend?

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Zcash liquidation heatmap.

Zcash has plunged nearly 50% from its recent high after disclosure of a critical network vulnerability triggered panic selling, forced liquidations, and the exit of one of the privacy coin’s most prominent supporters.

Summary

  • Zcash plunged nearly 50% after disclosure of a critical Orchard pool vulnerability and Arthur Hayes’ exit from the asset.
  • Lookonchain data showed a whale withdrew 37,316 ZEC worth $13.1 million from Binance, suggesting some investors are buying the dip.
  • Technical indicators remain bearish despite the rebound, with key resistance levels sitting at $420, $471, and $523.

According to crypto.news market data, Zcash (ZEC) crashed to an intraday low of $264.80 on June 5 before rebounding toward $380.

The selloff followed confirmation from Shielded Labs that a flaw in the network’s Orchard shielded pool could have allowed unlimited counterfeit ZEC to be created before an emergency fix was deployed.

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Selling pressure for the privacy token also intensified as BitMEX co-founder Arthur Hayes disclosed that he had sold his entire ZEC position. In a post on X, Hayes acknowledged that exploitation appeared “extremely unlikely” but argued that privacy-focused assets require a higher standard of certainty.

“The privacy from AI, govt, big tech narrative demands perfection not improbability. I read about the exploit yday, and didn’t appreciate how it violated my narrative mental map. The…dump, made me rethink, and I had to take profit on the entire position.”

Not everyone rushed for the exit, however. Lookonchain data showed a newly created wallet withdrew 37,316 ZEC worth approximately $13.1 million from Binance shortly after the crash, suggesting at least some large investors viewed the decline as a buying opportunity rather than a reason to abandon the asset.

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Whale accumulation emerges as traders target oversold conditions

On-chain activity shows a sharp divide between long-term believers and traders reducing exposure. While Hayes exited his position, the large Binance withdrawal arrived near the bottom of the selloff, coinciding with ZEC’s recovery from the $260 region.

Derivatives markets experienced one of the most violent resets in months. CoinGlass data cited earlier by crypto.news showed ZEC liquidations reached nearly $82 million during the crash as leveraged positions were wiped out across exchanges.

The three-day liquidation heatmap suggests much of the downside liquidity below $300 has already been cleared. Following the rebound, the largest concentration of short liquidation leverage sits between $370 and $390, with another significant cluster visible around the $450 region. If buyers maintain momentum above current levels, those zones could become magnets for price action as short sellers are forced to close positions.

Zcash liquidation heatmap.
Zcash liquidation heatmap | Source: CoinGlass

Market participants are also watching whether fresh accumulation continues. The recent whale purchase occurred after one of the largest single-day declines in Zcash’s recent history, creating conditions that often attract opportunistic traders seeking oversold assets.

Technical structure remains damaged despite rebound

The four-hour chart shows ZEC plunging through several key Fibonacci support levels after news of the Orchard vulnerability triggered heavy selling. The decline briefly pushed the token to an intraday low near $265, just above the 0% Fibonacci retracement level at $253, where buyers stepped in and sparked a sharp rebound.

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Zcash price, MACD and RSI chart.
Zcash price, MACD and RSI chart — June 6 | Source: crypto.news

Recovery has since pushed the token back above the 23.6% Fibonacci retracement level near $356. A successful hold above that area could open the door toward the next resistance zone at $420, which aligns with the 38.2% retracement level. Beyond that, traders are watching $471 and $523, corresponding to the 50% and 61.8% retracement levels.

Momentum indicators remain mixed. The Relative Strength Index has recovered from deeply oversold conditions but remains below the neutral 50 level, showing that buyers have regained some control without fully reversing the trend.

Meanwhile, the MACD remains below the zero line even as bearish momentum begins to ease. The histogram has started contracting after reaching its most negative reading during the selloff, suggesting that selling pressure has moderated following the liquidation cascade.

As such, if Zcash price fails to hold above the $356 support zone could expose ZEC to another test of the $300 area and potentially the recent low near $253. Such a move would likely invalidate the current recovery attempt and place attention back on the unresolved uncertainty surrounding the Orchard vulnerability.

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Disclosure: This article does not represent investment advice. The content and materials featured on this page are for educational purposes only.

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Cardano (ADA) Faces Make-or-Break Moment as Social Buzz and Network Activity Explode

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Cardano has become one of the most talked-about cryptocurrencies after its price briefly dropped below $0.16 for the first time since December 2020, according to on-chain analytics platform Santiment.

The surge in attention appears to be linked to growing concerns surrounding Cardano founder Charles Hoskinson, who recently said he was “taking a break” after warning that the ecosystem could face a “wave of failures” due to project shutdowns and funding difficulties.

Social Frenzy

According to Santiment’s data, the developments triggered a sharp increase in both social activity and on-chain engagement. Cardano’s social dominance climbed to around 0.52%, its highest level in 2026. This means that more than one in every 190 cryptocurrency-related discussions on social media focused on ADA.

At the same time, daily active addresses reached 28,459, representing the highest reading in four months. According to Santiment, the spike in network activity indicates that users were actively interacting with the blockchain as the sharp price volatility created strong divisions among traders. Bearish sentiment appears to be dominating much of the discussion.

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Despite the negative market reaction, Santiment explained that Cardano continues to have one of the most loyal and vocal communities in the crypto sector. The analytics firm said ADA holders have, for years, remained committed through multiple market cycles, and have often supported the network during periods when institutional participation was limited.

“The next few weeks and months will likely be a make-or-break stretch for the #15 market cap, as the community hopes institutionals consider entering into positions while prices are now at 5.5 year lows. Many investors are now looking for ecosystem growth, successful project launches, and of course some more positive future words from Hoskinson to validate the long-term vision that Cardano supporters have championed for years.”

Cardano – Brazilian Olympic Committee

In a separate development, the Cardano Foundation announced a partnership with the Brazilian Olympic Committee (COB) to bring blockchain, artificial intelligence (AI), and Internet of Things (IoT) technologies into the country’s sports sector.

According to the organizations, the three-year collaboration will focus on identity and certification systems, fan engagement, equipment tracking, and improving governance and transparency. The first pilot projects are expected to launch in the coming months.

The post Cardano (ADA) Faces Make-or-Break Moment as Social Buzz and Network Activity Explode appeared first on CryptoPotato.

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Jane Street Plans Major Data Center Expansion for AI Growth

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Crypto Breaking News

Jane Street is evaluating plans for a new data center as the quantitative trading firm seeks greater computing capacity to support artificial intelligence development and expanding trading operations. According to a Bloomberg report, the company has started preliminary discussions with businesses in the technology, cryptocurrency, and financial sectors regarding a potential facility.

The proposed project could provide between 100 and 200 megawatts of computing capacity. The company has not selected a location and has not finalized the size of the facility. However, the discussions reflect the firm’s growing focus on securing long-term infrastructure to meet increasing computational requirements.

Computing Capacity Becomes a Strategic Focus

Jane Street has significantly increased its demand for processing power in recent years and currently operates tens of thousands of graphics processing units, commonly known as GPUs. These processors support artificial intelligence workloads and large-scale computational tasks.

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Last month, Jane Street co-head of technology Ron Minsky outlined the company’s long-term plans for infrastructure growth. He explained the firm expects to achieve a tenfold increase in computing capacity over time. Minsky also stated that Jane Street aims to expand from tens of thousands of GPUs to hundreds of thousands in the coming years.

The company views computing resources as an important factor in supporting research and development efforts. Minsky noted that available computing power currently limits some research projects, experiments, and new initiatives. As a result, Jane Street continues to invest in additional infrastructure to support future growth.

AI Development Drives Infrastructure Demand

Jane Street intends to use the proposed data center primarily for internal operations. The facility would support the training of proprietary artificial intelligence models that assist with trading-related activities, including asset price forecasting and data analysis.

The company already operates a data center in Dallas and supplements its infrastructure through cloud service providers, including CoreWeave. The planned facility would add another layer of computing resources and help support future technology projects.

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Minsky also highlighted the importance of a distributed infrastructure strategy. He explained that a single facility cannot provide enough power to meet all future requirements. Therefore, the company expects to continue expanding computing resources across multiple locations.

Strong Trading Performance Supports Expansion

Jane Street’s infrastructure plans coincide with a period of substantial business growth as the firm reported a record $39.6 billion in trading revenue during the previous year. In the first quarter of this year, trading revenue reached $16.1 billion, more than double the figure recorded during the same period a year earlier.

The company continues to pursue more complex trading strategies and longer-duration positions across global markets. Consequently, demand for computing resources has increased as systems process larger volumes of data around the clock.

At the same time, competition for AI-related computing power is growing across the quantitative trading industry. Bloomberg reported that several firms are sourcing GPUs through cloud providers and secondary markets. This trend highlights the increasing importance of computing infrastructure as financial firms expand their use of artificial intelligence and advanced data-driven strategies.

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Risk & affiliate notice: Crypto assets are volatile and capital is at risk. This article may contain affiliate links. Read full disclosure

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XRP Ledger Prepares Version 3.2.0 Mainnet Upgrade Following Recent Network Improvements

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Crypto Breaking News

XRP Ledger Advances Toward Version 3.2.0 Deployment

The XRP Ledger ecosystem is preparing for another major mainnet upgrade as version 3.2.0 approaches release. The update introduces a software rebranding initiative and requires infrastructure operators to adjust their systems. Furthermore, the development follows the successful rollout of version 3.1.3 and continues the network’s upgrade roadmap.

XRP Ledger Operations announced that version 3.2.0 will reach the network in the near future. Consequently, the ecosystem has begun preparations for another important infrastructure transition. The update arrives shortly after the network completed its previous mainnet upgrade.

The upcoming release includes a significant change to the software powering the blockchain. Specifically, developers will rename the core software from rippled to xrpld. As a result, validators and node operators must adjust their existing configurations.

Infrastructure providers across the network will need to update their operational environments. Therefore, the transition will affect multiple participants responsible for maintaining network functionality. The operations team is also preparing guidance materials to support the migration process.

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Software Rebranding Marks Key Network Development

The software name change represents one of the central elements of the upcoming release. Accordingly, the update introduces a new identity for the software package that powers the XRP Ledger. The transition also aligns future development efforts under the xrpld designation.

Visual materials released alongside the announcement highlighted the updated branding. In addition, the materials displayed version 3.2.0 as the next software release. The presentation emphasized both the software transition and the forthcoming deployment.

Community members involved in network validation welcomed the development. Moreover, supporters highlighted the importance of continued protocol improvements despite broader market conditions. The response reflected ongoing confidence in the network’s technical progress.

The upgrade also reinforces XRP Ledger’s focus on long-term infrastructure development. Therefore, developers continue to prioritize network stability and operational efficiency. These efforts remain central to maintaining reliable blockchain performance.

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Recent Upgrade Provides Foundation For Next Release

Version 3.2.0 follows the activation of version 3.1.3 on the XRP Ledger mainnet. The earlier upgrade became active at ledger index 104,507,137 on May 27. Consequently, the network completed another scheduled improvement phase before moving forward.

The previous release introduced the fixCleanup3_1_3 amendment. In turn, the change aimed to strengthen long-term network reliability and performance. Developers designed the update to improve operational consistency across the ecosystem.

Older software versions lost compatibility with consensus participation after the activation. Therefore, node operators needed to upgrade their systems to remain connected. The requirement ensured that participants operated under the latest network standards.

Network developers also addressed technical questions following the earlier upgrade. Meanwhile, major amendments received full consensus support during the approval process. The unanimous backing demonstrated strong alignment among network validators.

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The forthcoming version 3.2.0 release extends XRP Ledger’s ongoing development cycle. As preparations continue, infrastructure operators are expected to complete the necessary system changes. The upgrade underscores the network’s commitment to modernization, reliability, and continued protocol advancement.

Risk & affiliate notice: Crypto assets are volatile and capital is at risk. This article may contain affiliate links. Read full disclosure

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Major US Banks Including JPMorgan, Citi and BofA Plan Shared Tokenized Deposit Network

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Major US Banks Including JPMorgan, Citi and BofA Plan Shared Tokenized Deposit Network


Four of the largest US commercial banks — JPMorgan Chase, Citigroup, Bank of America, and Wells Fargo — are building a shared tokenized deposit network through The Clearing House, the bank-owned payments company, according to a joint press release published Friday. The initiative, which The Wall… Read the full story at The Defiant

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Saylor Says Bitcoin Needs Disciplined Expansion as Demand Resets

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Saylor Says Bitcoin Needs Disciplined Expansion as Demand Resets

Strategy co-founder and executive chairman Michael Saylor said Bitcoin needs “disciplined expansion” through banks, companies, securities, credit and capital markets, laying out a path for the asset as spot exchange-traded fund (ETF) outflows and a broader market sell-off test institutional demand.

On Friday, Saylor published an essay, saying Bitcoin’s base layer should be treated as “sacred infrastructure,” with most innovation occurring through higher layers, applications, custody systems, credit instruments and financial infrastructure.

The comments frame Bitcoin’s next phase as a clash between two institutional channels: passive spot ETF exposure, which has broadened access but remains sensitive to redemptions, and the corporate and credit-market adoption model favored by Saylor’s Strategy.

Saylor argued Bitcoin should become embedded in the machinery of finance rather than depend only on spot buyers or ETF inflows. He said Bitcoin’s future requires balancing adoption, innovation and self-custody while preserving the network’s core properties.

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The essay comes during a sharp Bitcoin market sell-off that has put both major institutional channels under pressure. Spot Bitcoin ETFs posted weekly net outflows of $1.42 billion, $1.26 billion and $1 billion in the last three weeks of May, while the current week’s outflows have reached $1.4 billion so far.

Strategy also recently sold 32 Bitcoin to fund preferred stock dividends, its first sale since 2022, denting the “never sell” narrative that has long surrounded Saylor’s corporate Bitcoin strategy.

Spot Bitcoin ETF inflows and outflows in the last four weeks. Source: SoSoValue

Analysts split on demand reset 

The pressure has sharpened a broader debate over whether Bitcoin’s recent decline is a temporary reset after excessive leverage, or a sign that institutional demand is weakening after months of ETF-led buying.

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Lacie Zhang, research analyst at Bitget Wallet, said Bitcoin may already be closer to clearing the episode than equity markets after a $1.8 billion liquidation wave, deeply negative funding rates and a sharp reset in open interest. Zhang said a retest of $55,000 to $57,000 remains possible if outflows persist. She added:

“The key question is not just whether BTC holds $63K, but whether ETF flows stabilize, exchange reserves keep falling, and whale accumulation picks up.”

Nicolai Sondergaard, research analyst at Nansen, gave a more cautious view, saying exchange flow data suggests participants are using Bitcoin’s bounce from around $61,000 to reduce exposure rather than add to positions.

Sondergaard said Bitcoin’s ETF demand narrative has been unwinding since May, and that a durable recovery would require more than the removal of immediate market pressure. Without visible re-entry from institutional buyers, he said the market may struggle to rebuild momentum. 

Related: Strategy’s leveraged Bitcoin model has faced its first stress test: Grayscale

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Saylor argues for Bitcoin beyond ETFs

Saylor, in his essay, described four broad Bitcoin ideologies: maximalists, capitalists, technologists and fundamentalists. He said each group protects something important, but each can also go too far if its view becomes absolute.

The “disciplined expansion” thesis most closely fits the capitalist view, which treats Bitcoin as digital capital that can be integrated into balance sheets, securities, credit markets, banks, brokers, insurers and asset managers.

That framing differs from ETF-based exposure, where institutional adoption is measured largely through inflows and outflows.

Saylor’s preferred channel points to a more embedded model, where Bitcoin is used in corporate treasuries, collateral structures and capital markets rather than held only through spot investment products.

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Strategy’s BTC holdings versus USD value. Source: BitcoinTreasuries.net

Magazine: Bitcoin miners are pivoting to AI, so why is the hashrate near ATHs?

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Crypto Tax Proposals Weighed Ahead of Tuesday House Hearing

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Crypto Tax Proposals Weighed Ahead of Tuesday House Hearing

The US House Ways and Means Committee circulated seven discussion drafts of bills to address digital asset taxation ahead of a Tuesday hearing on the matter, covering stablecoins, staking, mining and transactions.

Among proposals in the draft legislation are reducing the tax paperwork required for crypto holders, providing clarity for mining and staking tokens and a potential “de minimis” reporting exception for transactions. The seven discussion draft bills preceded a Tuesday hearing on digital asset taxation in the House committee, chaired by Republican Jason Smith.

Crypto industry advocates have been urging US lawmakers to address lessening the reporting burden for taxes on mining and staking as well as eliminating requirements for small crypto transactions through “de minimis” exceptions.

A draft law released by members of Congress in March and officially introduced in May as the Digital Asset PARITY Act proposed a $200 reporting threshold for stablecoin transactions, but not one on cryptocurrencies like Bitcoin.

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“We need digital asset tax clarity or activity will never fully onshore,” said The Digital Chamber CEO Cody Carbone in response to the PARITY Act.

Source: Max Miller

Any bill or amendment to legislation addressing crypto tax policy will need bipartisan support in Congress before being signed into law. Although the House hearing is scheduled for Tuesday, US lawmakers in the Senate are expected to focus on a budget reconciliation bill before consideration of a digital asset market structure bill called the CLARITY Act.

Related: Israel’s tax authority ‘disappointed’ in voluntary crypto disclosures: Report

According to Wyoming Senator Cynthia Lummis, the House Ways and Means Committee and the Senate Finance Committee were considering a $300 “de minimus” exemption for Bitcoin transactions. The proposed change to capital gains taxes built upon the Wyoming lawmaker’s draft bill released in July 2025.

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Illinois crypto tax expected to be signed into law soon

This week, the Illinois General Assembly signed off on a $56 billion state budget that included provisions for taxing digital assets. If signed into law by Governor JB Pritzker, crypto users can expect to pay a 0.2% tax on transactions through brokers, which also must be registered with the state.

Magazine: Bitcoin miners are pivoting to AI, so why is the hashrate near ATHs?

Cointelegraph is committed to independent, transparent journalism. This news article is produced in accordance with Cointelegraph’s Editorial Policy and aims to provide accurate and timely information. Readers are encouraged to verify information independently.

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Top US Banks to Launch Tokenized Deposit Network: Report

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The biggest banks on Wall Street are reportedly going to launch a tokenized deposit network in the first half of 2027.

The effort is being led by the Clearing House, a real-time payments company co-owned by major financial institutions including JPMorgan Chase, Bank of America, Citigroup, and Wells Fargo.

Project to Bridge Traditional Payments with Blockchain

The Wall Street Journal reports that the project, called “the bridge,” aims to connect traditional banking payment systems to blockchain infrastructure so that tokenized deposits can move instantly with 24/7 settlement. It also states that the underlying blockchain will be built through a partnership with a yet-to-be-selected third-party vendor.

“This is a big move for the banks,” said Clearing House Chief Executive David Watson, who said the industry is facing a “radically different” future when it comes to on-chain payments and finance.

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Citi sees the initiative as an extension of the role banks already play in the financial system. The move was “another step that effectively cements” banks’ role in financing, money management, and capital markets, said Shahmir Khaliq, the firm’s head of services.

At the same time, banks have been wary about stablecoins, concerned that their use could divert deposits away from the firms. Financial institutions and crypto institutions have been at loggerheads for months over recently advanced legislation that would allow the latter’s customers to earn interest from their stablecoin holdings.

Demand For Adoption Remains Gradual

The report states that all US banks will have access to the tokenized deposit network, with possible use cases including real-time liquidity management, programmable treasury operations, and cross-border payments. The Clearing House also expects big multinationals to be among its first users.

On the other hand, Mark Monaco, head of global payment solutions at Bank of America, said clients are not “beating down the door” for tokenized deposits yet. However, he also revealed that there is growing interest in the product, further admitting that adoption would take time.

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JPMorgan has already dipped its toes with JPM Coin, an in-house tokenized deposit system for settling payments on its private blockchain. More recently, the firm also launched a token on Base for its institutional clients.

The latest development follows last year’s discussions among major financial institutions about creating a joint stablecoin through The Clearing House and Early Warning Services. As much as this is still being explored, WSJ said that some banking executives are still unsure about the benefits that these digital assets offer outside of cross-border payments.

The post Top US Banks to Launch Tokenized Deposit Network: Report appeared first on CryptoPotato.

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Travala Launches AI Hotel Booking Protocol With USDC on Base

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Agentic payments surpass 100M transactions on Coinbase's Base

Singapore-based crypto travel platform Travala has launched a protocol it says lets artificial intelligence agents search, reserve and pay for hotels with USDC (USDC) on layer-2 blockchain Base, extending agentic AI stablecoin payments into travel bookings.

The Travala Travel MCP is live through Claude Desktop, with outside developers able to integrate it into their own travel agents, Travala said in a statement sent to Cointelegraph.

The company said the system connects Travala’s hotel inventory to AI agents through the Model Context Protocol, an open standard for linking AI apps to external tools. Payments use Coinbase’s x402 protocol on Base, with Travala saying the setup allows gasless USDC transactions, near-instant settlement and transaction costs of about $0.01 per booking.

AI travel still needs human approval

However, final payment authorization still requires manual approval from the traveler, meaning it’s not fully autonomous but more advanced than a chatbot that only recommends itineraries.

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The launch comes as crypto companies try to make stablecoins useful for machine-to-machine commerce and follows a wave of crypto payment infrastructure aimed at AI agents. Cointelegraph reported recently that x402-linked wallets on Base surpassed 100 million transactions, while Fireblocks, MoonPay, Exodus and Oobit have launched products for AI-driven stablecoin payments.

Cumulative agentic transfer volumes on Base. Source: Chainalysis

Travala framed the launch as an early step toward autonomous travel booking, even as travelers still retain final approval over payments, and said it is offering developers a 10% Coinbase Wrapped BTC (cbBTC) rebate on completed stays booked through its agents.

“The launch of the world’s first agentic AI travel protocol marks the death of the checkout button,” Travala CEO Juan Otero said, calling it the start of “a truly autonomous travel economy.”

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Travala said the setup uses ERC-7715 session keys, allowing the AI agent to request a payment while keeping final signing authority inside the traveler’s wallet. The company said the protocol can maintain context across searches, bookings and cancellations in a single chat thread.

Related: Coinbase-backed x402 adds batch settlement for AI agent payments

Travala plans broader travel rollout

Travala said the protocol covers more than 2.2 million hotels, including listings from Marriott, Hilton and IHG, which are sourced through its aggregator partners. 

The company said it plans to expand the protocol beyond hotels to other travel products, including flights, and expects its Travala (AVA) loyalty token to support future Travel MCP use cases.

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Travala was founded in 2017 and competes with crypto-friendly travel platforms such as Sleap.io and Alternative Airlines, though its latest protocol shifts the comparison from crypto checkout toward AI-agent booking infrastructure. The company says it accepts more than 100 cryptocurrencies alongside fiat currencies. 

Magazine: AI-driven hacks could kill DeFi — unless projects act now

Additional reporting by Christina Comben.

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Healthcare Sector Sees Stealth Rally as Institutional Money Flows In

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LLY Stock Card

Key Takeaways

  • A defensive rotation is driving capital flows from technology and AI stocks into healthcare equities
  • The Health Care Select Sector SPDR Fund surged 3% Thursday, piercing key technical resistance levels
  • UnitedHealth and Eli Lilly dominate S&P Health Care index rankings with Quant scores of 3.47 and 3.44
  • Artificial intelligence technology enables pharmaceutical companies to evaluate 50 times more drug candidates than traditional methods
  • Individual opportunities emerge in companies like Intuitive Surgical, Natera, and Edwards Lifesciences amid broader sector recovery

A stealth rotation into healthcare equities is underway as institutional investors reposition portfolios away from overheated technology names. The convergence of defensive positioning and artificial intelligence breakthroughs is reviving interest in a sector that has languished for years.

Thursday’s trading session saw the Health Care Select Sector SPDR Fund climb 3%, simultaneously breaking through a critical short-term technical barrier. Market analysts interpret this price action as evidence of strengthening sector momentum.

Surging volume in managed care equities signals institutional capital allocation toward healthcare. After years of trailing the broader equity markets, this sector rotation represents a meaningful shift in investor sentiment.

The healthcare segment of the S&P 500 has declined 4% year to date, with projected full-year earnings expansion of merely 4%—the weakest among all sectors.

Political pressure on pharmaceutical pricing, declining Affordable Care Act participation, and Merck’s substantial one-time write-down have created sector headwinds. However, beneath these challenges, pockets of robust growth are emerging.

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Artificial Intelligence Transforms Drug Development Pipelines

Pharmaceutical and biotechnology firms are deploying artificial intelligence systems to accelerate and economize drug candidate screening. Shivani Vohra, portfolio manager at Parnassus Investments, notes that computational models now perform tasks historically requiring laboratory personnel.

“Anywhere from five to 50 times the number of early-stage candidates are being looked at,” Vohra said. This technological leap enables companies to identify superior drug candidates with unprecedented efficiency.

This innovation represents a compelling reason for investors to look beyond near-term sector challenges.

Standout Equity Opportunities in Healthcare

[[LINK_START_1]]Eli Lilly[[LINK_END_1]] dominates the sector landscape. The pharmaceutical giant’s GLP-1 medications targeting obesity and diabetes are projected to generate approximately $22 billion in free cash flow this year, with forecasts reaching $47 billion by 2030. The stock currently trades at 31 times forward earnings.


LLY Stock Card
Eli Lilly and Company, LLY

Intuitive Surgical manufactures the widely-adopted da Vinci robotic surgical platform, now considered essential infrastructure across hospital systems. The company is launching its first major platform upgrade in ten years, featuring enhanced computing capabilities and advanced imaging technology. Following a 25% decline over twelve months, shares trade at 40 times earnings.

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Natera provides specialized blood diagnostics for prenatal care and oncology applications. Analysts project revenue will exceed $5 billion before decade’s end, more than doubling current levels, though profitability remains elusive.

Edwards Lifesciences is expanding beyond traditional heart valve replacement into emerging, high-growth valve therapy categories. The stock commands a 29 times earnings multiple.

Medline, which completed its public offering in December at $29 per share, recently traded below $35. The medical products supplier operates a private-label business model and trades at 23 times earnings.

Current Quant Rating Landscape

[[LINK_START_3]]UnitedHealth[[LINK_END_3]] and Eli Lilly command the top positions within the S&P Health Care index based on Quant Rating methodology, scoring 3.47 and 3.44 respectively. Both equities have recorded recent price appreciation.

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Johnson & Johnson, Thermo Fisher Scientific, and Intuitive Surgical occupy subsequent ranking positions. Notably, no top-weighted holdings currently achieve a bullish Quant Rating exceeding 3.5, with the majority residing in neutral hold territory.

Abbott Laboratories registers the weakest performance score at 2.71, nearing bearish classification.

AbbVie, Gilead Sciences, and Abbott cluster at the lower end of sector rankings.

The overall sector profile suggests cautious optimism, with selective opportunities emerging as healthcare begins establishing a firmer foundation for sustained outperformance.

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