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Colorectal Cancer Now Leading Cause of Cancer Deaths in Americans Under 50, New Data Show

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Colorectal Cancer Now Leading Cause of Cancer Deaths in Americans

Colorectal cancer has become the leading cause of cancer-related deaths among adults under age 50 in the United States, surpassing other major malignancies as overall cancer mortality in this age group continues to decline sharply, according to recent analyses from the American Cancer Society and published research.

Colorectal Cancer Now Leading Cause of Cancer Deaths in Americans
Colorectal Cancer Now Leading Cause of Cancer Deaths in Americans Under 50, New Data Show

A study released January 22, 2026, in the Journal of the American Medical Association examined U.S. cancer death trends from 1990 through 2023 for the five leading causes in people younger than 50. Researchers found that total cancer deaths in this demographic dropped 44 percent over the period, from 25.5 per 100,000 people in 1990 to 14.2 in 2023. Declines occurred in four of the top five causes — brain cancer (0.3 percent annual drop from 2014-2023), breast cancer (1.4 percent), leukemia (2.3 percent) and lung cancer (5.7 percent) — reflecting advances in prevention, early detection and treatment.

Colorectal cancer stood alone as an outlier. Mortality rose by an average of 1.1 percent annually since 2005, propelling it from the fifth-leading cause in the early 1990s to the top spot by 2023 — seven years earlier than some projections had anticipated. The disease now ranks first overall for cancer deaths under 50, second for women (behind breast cancer) and first for men.

“Overall progress against cancer in young adults has been remarkable, but colorectal cancer is moving in the wrong direction,” said Rebecca L. Siegel, senior scientific director of surveillance research at the American Cancer Society and lead author of the JAMA research letter. “This confirms a real increase in underlying risk for generations born after about 1950.”

The American Cancer Society’s “Colorectal Cancer Statistics, 2026” report, published in March, reinforced the trend. It projected 158,850 new colorectal cancer cases and 55,230 deaths nationwide this year, with incidence rising 3 percent annually in adults aged 20-49 and 0.4 percent in those 50-64, while falling 2.5 percent in those 65 and older. Mortality has climbed 1 percent per year since 2004 in those under 50 and since 2019 in the 50-64 group.

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The shift is driven largely by tumors in the distal colon and rectum. About one in five diagnoses now occurs in people under 55, up from far lower proportions decades ago. Younger patients are more likely to present with advanced-stage disease, contributing to poorer outcomes.

Experts attribute the rise to a mix of factors, though no single cause has been pinpointed. Potential contributors include changes in diet (higher processed foods, red meat and low fiber), sedentary lifestyles, obesity, diabetes, antibiotic use altering gut microbiomes and environmental exposures. Unlike older adults, where screening has driven steep declines, many under 50 lack routine checks, delaying diagnosis until symptoms like bleeding, pain or bowel changes appear — often dismissed as benign issues in younger people.

In response, major guidelines now recommend colorectal cancer screening starting at age 45 for average-risk adults, down from 50. Options include colonoscopy every 10 years, annual fecal immunochemical tests or stool DNA tests every three years. Uptake of non-invasive stool tests has risen, helping offset pandemic-related drops in colonoscopies.

The Colorectal Cancer Alliance called the findings a wake-up call, urging greater awareness, symptom education and involvement in research initiatives like Project Cure CRC to accelerate treatments.

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Despite the alarming trend in young adults, overall U.S. colorectal cancer mortality has fallen 56 percent since 1970 due to screening, reduced smoking and better therapies. Yet progress has slowed recently, with rates stable from 2020-2023 after earlier annual declines of about 2 percent.

Advocates stress that many deaths could be prevented through earlier detection. Symptoms in younger people — persistent abdominal pain, unexplained weight loss, changes in bowel habits or rectal bleeding — warrant prompt medical attention, even if uncommon for the age group.

Ongoing research explores why incidence surges in post-1950 birth cohorts, with calls for more etiologic studies into modern lifestyle and environmental factors. As these generations age, the burden may grow without intervention.

Health organizations emphasize equity: screening gaps persist in underserved communities, where stool-based tests show promise for accessibility and cost.

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The data highlight a paradox — broad success against cancer in young adults overshadowed by one disease’s relentless rise. Experts urge clinicians to consider colorectal cancer in symptomatic patients under 50 and public campaigns to normalize screening discussions.

With March designated Colorectal Cancer Awareness Month, groups promote blue-ribbon campaigns to boost awareness and early action.

As the trend persists into 2026, the message remains clear: colorectal cancer is no longer just an older person’s disease. Vigilance, lifestyle changes and timely screening offer the best defense against what has become the top cancer killer for Americans in their prime working and family years.

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Why both partners need to be across a couple's money

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Why both partners need to be across a couple's money

Martin Lewis explains why both partners in a relationship need to know what financial products they hold.

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Invesco Rising Dividends Fund Q4 2025 Commentary (Mutual Fund:OARDX)

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Invesco Rising Dividends Fund Q4 2025 Commentary (Mutual Fund:OARDX)

Invesco is an independent investment management firm dedicated to delivering an investment experience that helps people get more out of life.Be the first to know! Sign up for Invesco US Blog and get expert investment views as they post.Disclosure for all Invesco US articles: Before investing, carefully read the prospectus and/or summary prospectus and carefully consider the investment objectives, risks, charges and expenses. The information provided is for educational purposes only and does not constitute a recommendation of the suitability of any investment strategy for a particular investor. Invesco does not provide tax advice. The tax information contained herein is general and is not exhaustive by nature. Federal and state tax laws are complex and constantly changing. Investors should always consult their own legal or tax professional for information concerning their individual situation. The opinions expressed are those of the authors, are based on current market conditions and are subject to change without notice. These opinions may differ from those of other Invesco investment professionals. NOT FDIC INSURED MAY LOSE VALUE NO BANK GUARANTEE All data provided by Invesco unless otherwise noted. Invesco Distributors, Inc. is the US distributor for Invesco Ltd.’s retail products and collective trust funds. Invesco Advisers, Inc. and other affiliated investment advisers mentioned provide investment advisory services and do not sell securities. Invesco Unit Investment Trusts are distributed by the sponsor, Invesco Capital Markets, Inc., and broker-dealers including Invesco Distributors, Inc. PowerShares® is a registered trademark of Invesco PowerShares Capital Management LLC (Invesco PowerShares). Each entity is an indirect, wholly owned subsidiary of Invesco Ltd. ©2015 Invesco Ltd. All rights reserved.

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Form 8K Trinseo SA For: 13 March

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Form 8K Trinseo SA For: 13 March

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Sebi sets new conditions for intraday borrowing by mutual funds from April 1

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Sebi sets new conditions for intraday borrowing by mutual funds from April 1
Capital markets regulator Sebi on Friday issued new conditions for intraday borrowing by mutual funds to address temporary liquidity mismatches while putting in place safeguards to ensure investor protection. The new framework will come into effect from April 1.

Sebi said mutual funds often face intraday timing mismatches between redemption payouts and inflows from investments. Typically, redemption payments to investors are processed during the morning hours of the settlement day (T+1), while funds from instruments such as TREPS and reverse repo transactions are received later in the evening.

To bridge this temporary funding gap, mutual fund schemes sometimes rely on short-term borrowing arrangements from banks or other financial institutions. The regulator said the new rules formally recognise this practice while placing clear limits and operational conditions.

Mutual funds are generally allowed to borrow up to 20% of the net assets of a scheme for a maximum period of six months for purposes such as meeting redemption requests, paying income distribution or settling certain trades. However, this 20% cap will not apply to intraday borrowings, provided they meet specific conditions laid out by the regulator.

Sebi clarified that intraday borrowing can be used only to facilitate repurchase or redemption of units, interest payments or income distribution payouts to unitholders.

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The regulator also capped the quantum of intraday borrowing. The amount borrowed cannot exceed receivables guaranteed on the same day from institutions such as the Government of India, the Reserve Bank of India, and the Clearing Corporation of India.
Eligible receivables include maturity proceeds from TREPS, reverse repo transactions, government securities, treasury bills, state development loans, STRIPS, as well as interest payments and sale proceeds from these instruments.To strengthen oversight, Sebi has mandated that each asset management company’s board and trustees must approve a formal policy governing the use of intraday borrowing facilities, which must also be disclosed on the AMC’s website.

The regulator further said that any cost associated with intraday borrowing must be borne by the asset management company, not by the mutual fund scheme or its investors. Similarly, any losses arising from delays or unforeseen issues in receiving expected funds must also be absorbed by the AMC.

Sebi also addressed borrowing by equity-oriented index funds and exchange-traded funds (ETFs). Such funds will be allowed to borrow funds in cases where sell trades are not executed on time, but only to facilitate participation in the closing auction session of stock exchanges, which will become effective from August 3.

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Retail prices could rise after Strait of Hormuz closure

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Retail prices could rise after Strait of Hormuz closure

The Iran war could soon mean higher prices on store shelves for consumers.

Iran’s effective closure of the Strait of Hormuz passage has significantly disrupted the global supply chain, affecting goods from fertilizers to metals to gas and fuel. The passage is a critical point, funneling tens of millions of barrels of oil daily along with other exports as one of the world’s most important shipping routes.

And the tensions with the strait are showing no signs of changing. On Thursday, Iran’s new supreme leader, Mojtaba Khamenei, said the closure should be continued as a “tool to pressure the enemy” in his first public statement since being appointed. Defense Secretary Pete Hegseth on Friday downplayed concerns about the strait, saying at a Pentagon press briefing, “We have been dealing with it, and don’t need to worry about it.”

Though it’s still early to determine what the exact impact on retail may be, Coresight Research President Max Kahn said the disruption to the global supply chain may already be pushing the industry near its limits.

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“Retailers have become much better at building flexibility in their supply chains, and that got accelerated a lot last year with tariffs,” Kahn told CNBC. “The bigger worry is if this continues to last.”

Prices at the grocery store may be hit first, Kahn said, since food items tend to have less flexible supply chains, while apparel retailers can likely afford to slow production and bulk it up again later without disrupting inventory.

As retailers navigate the geopolitical landscape, Kahn said they’ll likely be facing two factors: input cost pressure and demand pressure.

“Retailers are going to have to play that,” he said. “One of the reasons how retail stayed resilient in 2022 and 2023 was they were able to raise prices, and that raising of prices sort of offset some weakening in units, so our sense would be that that could be very similar this time around.”

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Retail hasn’t just been affected by shipping changes, either. Shipments of garments for Zara owner Inditex, along with other clothing retailers, were stranded last week as flights in the Middle East were canceled, according to Reuters.

Kahn said retailers’ potential struggles could have broader economic implications, too. Though companies have learned to be somewhat adaptable to the changing macroeconomic environment over the past few years, he noted that the overall growth for retail has been “so-so,” and while the industry continues to navigate the war, that uncertainty will also begin to affect GDP growth.

Still, as the chaos persists, Kahn said he expects value retailers like Walmart and Kroger and dollar stores like Dollar General and Dollar Tree to have an easier time because shoppers will be looking for more value-priced items.

In addition to impacting the global supply chain, consumer confidence is already taking a hit from the war. Though Wednesday’s consumer price index came in as expected, industry experts have said higher gas prices will likely affect discretionary spending as consumers pull back to cover costs at the pump, affecting the retailers that may already be reeling from supply chain impacts.

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In a Sunday note, Wolfe Research analysts wrote that discretionary-heavy retailers are likely to be among the largest losers from the war.

“Retailers with a bigger discretionary mix, like Five Below and Target, also face headwinds as consumer confidence comes under pressure and they mix down,” they wrote.

Still, some retailers may have other factors helping them out of the war fallout. Retailers that appeal to higher-income consumers or who have specialty offerings, like Costco, may be able to escape the squeeze.

“Costco should benefit as their price leadership on gas becomes more important, and consumers are more willing to wait 20+ minutes for gas,” the analysts added.

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UBS analysts wrote in a Monday note that the war is adding uncertainty to an already weakened consumer dealing with the changing macroenvironment and the K-shaped economy, where those at the high end continue to do well while lower-income consumers struggle.

“The rise in oil prices should add a meaningful burden to household budgets and intensify strains already visible across the consumer landscape,” they wrote.

While some retailers like Ulta and Costco have historically seen same store sales increase alongside oil inflation, companies that serve lower-income shoppers like Ollie’s Bargain Outlet and Dollar General are likely to see sales decrease as consumers face budget restraints, the UBS analysts said.

“All in, the rise in oil prices could create a layered and persistent drag on consumer health,” they wrote. “It increases fixed household expenditures, puts upward pressure on grocery prices, reshapes retail traffic patterns and introduces operational challenges for retailers across multiple segments.”

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Why has Trump eased sanctions on Russian oil – and will it help Putin?

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Why has Trump eased sanctions on Russian oil - and will it help Putin?

The US said easing sanctions on Russian oil would provide only a limited financial boost to Putin.

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Big Tech Stocks Have a Free Cash Flow Problem

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Big Tech Stocks Have a Free Cash Flow Problem

Big Tech Stocks Have a Free Cash Flow Problem

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Sebi imposes Rs 10 lakh fine on Anand Rathi for violation of stock brokers’ norms

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Sebi imposes Rs 10 lakh fine on Anand Rathi for violation of stock brokers' norms
Market regulator Securities and Exchange Board of India (Sebi) on Friday imposed a fine of Rs 10 lakh on Anand Rathi Share and Stock Brokers Limited after finding the company in violation of its stock brokers regulation.

In its investigation launched on June 17, 2025, the market watchdog found the brokerage lacking in compliance related to several stock brokers’ regulations. The inspection was conducted for the period between April 1, 2023 and August 31, 2024.

In a 42-page order, Sebi held that Anand Rathi failed in reporting technical glitches that occurred on May 21, 2024 within the stipulated time.

The company in its defence, said that it had intimated the exchanges about the glitch with an hour of the incident while submitting the preliminary report on the next day. However, it admitted the delay in the submission of Root Cause Analysis (RCA).

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The order also noted that Anand Rathi breached the capacity utilization threshold limit by setting it at 85% & 95%, going beyond 70 % of installed capacity.


The brokerage firm was also found to be in violation of patch management norms.
Among other things, Anand Rathi violated provisions related to the password policy.Sebi also found that Anand Rathi did not have adequate data leakage prevention (DLP) systems in place during the inspection period, as required under Securities and Exchange Board of India regulations and National Stock Exchange of India guidelines.

Although the broker claimed it had earlier deployed a McAfee solution in 2020 and later implemented Zscaler, Sebi noted that the McAfee subscription had expired in December 2021 and there was no proof of renewal or active use during the inspection period. Evidence provided for the Zscaler system showed implementation only after the inspection.

Accordingly, SEBI concluded that the broker had violated data security provisions requiring deployment of tools to detect and prevent data leakage.

(Disclaimer: The recommendations, suggestions, views, and opinions given by the experts are their own. These do not represent the views of The Economic Times.)

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WBC 2026 South Korea vs Dominican Republic Preview: Who Will Win?

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Port Vale FC

The 2026 World Baseball Classic knockout stage kicks off with a high-stakes quarterfinal matchup Friday as the powerhouse Dominican Republic faces a resilient South Korea team at loanDepot Park in Miami.

WBC 2026
WBC 2026

First pitch is scheduled for 6:30 p.m. ET, with the game airing on FS2 in the United States. The winner advances to Sunday’s semifinal to face the victor of the United States-Canada quarterfinal, while the loser is eliminated from contention for the championship.

The Dominican Republic enters as overwhelming favorites after dominating Pool D with a perfect 4-0 record, outscoring opponents by wide margins and showcasing explosive offense. Led by stars like Juan Soto, Vladimir Guerrero Jr., Manny Machado, and Fernando Tatis Jr., the D.R. lineup has been one of the tournament’s most feared, combining power hitting with disciplined plate appearances. They capped pool play with a 7-5 win over rival Venezuela on March 12, solidifying their status as a top contender to claim the nation’s first WBC title since 2013.

South Korea, finishing as Pool C runner-up with a 2-2 record, advanced via a complex tiebreaker scenario involving Australia and Chinese Taipei. The Koreans scraped through group play, highlighted by a 7-2 win over Australia that secured their spot. Their offense has been led by first baseman Bo Gyeong Moon, who paced the tournament with 11 RBI and a .538 average (7-for-13) through pool games, including two home runs and two doubles. Pitching has been a strength in spots, with relievers limiting damage despite some vulnerabilities.

This marks the first WBC meeting between the two nations, adding intrigue to the clash of styles. The Dominican Republic brings MLB-caliber star power and depth, while South Korea relies on disciplined fundamentals, strong starting pitching, and opportunistic hitting from a mix of KBO standouts and MLB contributors like Jung Hoo Lee (San Francisco Giants) and Hyeseong Kim (Los Angeles Dodgers).

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Probable starters feature a veteran vs. rising star dynamic: left-hander Hyun Jin Ryu for South Korea against lefty Cristopher Sánchez for the Dominican Republic. Ryu, a former MLB All-Star with the Dodgers and Blue Jays, brings experience and command, though his recent form in international play will be tested against the D.R.’s potent lineup. Sánchez, emerging as a reliable arm for the Phillies, offers swing-and-miss stuff and ground-ball tendencies that could neutralize Korea’s contact-oriented approach.

Betting markets heavily favor the Dominican Republic, with opening lines listing them as -750 to -900 money-line favorites on major sportsbooks, while South Korea sits as a +500 to +550 underdog. The run line stands at D.R. -4.5 around -105 to -115, and totals hover at 9.5 to 10.5 runs, reflecting expectations for offensive fireworks from the Dominicans potentially offset by solid pitching duels.

Analysts point to the Dominican Republic’s multi-pronged attack as the deciding factor. Their pool performance included slugging outbursts, high walk totals, and lockdown relief work, making them look like the tournament’s most complete team. South Korea, while gritty and capable of upsets—evidenced by their near-miss against defending champion Japan—struggled with consistency in group play, particularly against stronger opponents.

Key storylines include the Dominican Republic’s quest to avenge past international disappointments and South Korea’s bid to reach the semifinals for the first time since their 2009 runner-up finish. Manager Albert Pujols, a baseball icon, has emphasized preparation and execution, while Korea’s staff highlights resilience and fundamentals in facing elite competition.

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The venue, loanDepot Park, offers neutral conditions with potential for carry on fly balls, favoring power hitters like those in the D.R. lineup. Capacity crowds are expected, with passionate fans from both nations anticipated to create an electric atmosphere.

A Dominican victory would set up a high-profile semifinal, while a South Korean upset could spark one of the tournament’s biggest surprises and propel the underdog story forward. As the quarterfinals begin, this matchup encapsulates the WBC’s blend of star power, national pride, and unpredictable drama.

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Adobe pays $75 million to settle US lawsuit over termination fees, subscription cancellations

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Adobe pays $75 million to settle US lawsuit over termination fees, subscription cancellations


Adobe pays $75 million to settle US lawsuit over termination fees, subscription cancellations

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