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Wave Life Sciences Ltd. (WVE) Q4 2025 Earnings Call Transcript

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Q4: 2026-02-26 Earnings Summary

EPS of -$0.30 misses by $0.04

 | Revenue of $17.24M (-79.41% Y/Y) beats by $1.57M

Wave Life Sciences Ltd. (WVE) Q4 2025 Earnings Call February 26, 2026 8:30 AM EST

Company Participants

Kate Rausch – Head of Investor Relations
Paul Bolno – President, CEO & Director
Christopher Wright – Chief Medical Officer
Kyle Moran – CFO & Principal Accounting Officer
Erik Ingelsson – Chief Scientific Officer

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Conference Call Participants

Jenny Leigh Gonzalez-Armenta – Leerink Partners LLC, Research Division
Salim Syed – Mizuho Securities USA LLC, Research Division
Steven Seedhouse – Cantor Fitzgerald & Co., Research Division
Joon Lee – Truist Securities, Inc., Research Division
Alec Stranahan – BofA Securities, Research Division
Madison Wynne El-Saadi – B. Riley Securities, Inc., Research Division
Catherine Novack – JonesTrading Institutional Services, LLC, Research Division
Cheng Li – Oppenheimer & Co. Inc., Research Division
Angela Qian – Canaccord Genuity Corp., Research Division
Craig McLean – Wells Fargo Securities, LLC, Research Division
Cha Cha Yang – Jefferies LLC, Research Division
Cassie Yuan

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Presentation

Operator

Good morning, and welcome to the Wave Life Sciences Fourth Quarter and Full Year 2025 Earnings Conference Call. [Operator Instructions] As a reminder, this call is being recorded and webcast.

I’ll now turn the call over to Kate Rausch, Vice President of Corporate Affairs and Investor Relations. Please go ahead.

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Kate Rausch
Head of Investor Relations

Thank you, Sophie, and good morning to everyone on the call. Earlier this morning, we issued a press release outlining our fourth quarter and full year 2025 earnings update. Joining me today with prepared remarks are Dr. Paul Bolno, President and Chief Executive Officer; Dr. Chris Wright, Chief Medical Officer; and Kyle Moran, Chief Financial Officer. Dr. Eric Ingelsson, Chief Scientific Officer, will be available for questions after the call. The press release issued this morning is available on the Investors section of our website, www.wavelifesciences.com.

Before we begin, I would like to remind you that discussions during this conference call will include forward-looking statements. These

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