Oprah Winfrey Shows Off Dramatic Weight Loss Transformation

Oprah Winfrey stepped out at the Telluride Film Festival after speaking candidly about the role GLP-1 medication has played in her health journey. The television icon attended the North American premiere of “Everest: The Other Side” in Colorado on Saturday, where she interviewed ski mountaineer Jim Morrison in front of a live audience. Winfrey’s festival appearance comes months after she revealed she had reached 155 pounds and explained why she no longer blames herself for her longtime struggles with weight.

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Winfrey arrived at the event in a cream-colored jacket and matching trousers featuring feathery details. The 72-year-old completed the outfit with a white tank top, brown boots, earrings and sunglasses. Her hair fell past her shoulders in voluminous waves.

Winfrey posed for photographs outside the venue and was later seen alongside her longtime friend Gayle King.

Winfrey Shows Off Slim Figure While Chatting With Jim Morrison

The media mogul subsequently joined Morrison onstage for a conversation connected to “Everest: The Other Side.” The documentary follows Morrison and the late mountaineer Hilaree Nelson as they attempt to climb and ski Mount Everest’s direct north face.

The project also explores grief and resilience following Nelson’s death during a 2022 descent of Mount Manaslu.

The TV Icon Has Been Candid About Her Weight Loss

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Winfrey’s appearance follows a series of candid interviews about her decades-long struggle with weight and her eventual decision to use GLP-1 medication. During a January appearance on “The View,” she reflected on the constant thoughts about food, calories, and exercise that once occupied her mind.

“All these years… I was standing there with all the food noise, [thinking about] what I ate, what I should eat, how many calories was [in what I ate],” Winfrey said. “And how long it was going to take [to burn off]. And I thought that was because of me and that it was my fault.”

Winfrey said her understanding of obesity changed after learning more about its biological and genetic components. She explained that she now “understands that if you carry the obesity gene, that is what makes you overeat. You don’t overeat and become obese; obesity causes you to overeat.”

“Obesity causes you to have all that food noise. What GLP-1s have done for me and a number of other people is quiet that noise,” Winfrey added.

The Centers for Disease Control and Prevention notes that obesity is complex and that “no single genetic cause has been identified” in most cases. Genetics can influence obesity, but environmental, behavioral and other biological factors can also play a role.

Oprah Winfrey Revealed She Reached 155 Pounds

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Earlier this year, Winfrey revealed that she had reached 155 pounds, which she described as her marathon weight. The figure represents an 82-pound difference from the 237 pounds she previously identified as her highest weight. “I thought it was about discipline and willpower. But I stopped blaming myself,” she told PEOPLE. “I feel more alive and more vibrant than I’ve ever been.”

Winfrey has also emphasized that medication is only part of her health routine. She reportedly incorporates activities such as hiking, treadmill workouts, and weightlifting into her lifestyle. Her experiences helped inspire the book “Enough: Your Health, Your Weight, And What It’s Like To Be Free,” which she co-wrote with obesity specialist Dr. Ania Jastreboff.

She Regained Weight After Stopping The Medication

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Winfrey has also revealed that she temporarily stopped using GLP-1 medication because she wanted to see whether she could maintain her results without it. “I was off of the medications all last year, and I gained 20 pounds because I wanted to test it,” she recalled. “Because everybody was saying, ‘you’re going to gain the weight’… I’m going to show them… I’m going to hike.”

However, Winfrey said thoughts about food gradually returned, even though she kept making healthy choices. “And then I was taking it, then I got off of it, and then I gained three pounds, and I gained five pounds, and I gained 10 pounds, and before you know it, the [food] noise was back,” she explained.

PEOPLE reported that Winfrey stopped the medication for 12 months before deciding it was an important long-term tool for managing her health.