Key Takeaways

• A defensive rotation is driving capital flows from technology and AI stocks into healthcare equities
• The Health Care Select Sector SPDR Fund surged 3% Thursday, piercing key technical resistance levels
• UnitedHealth and Eli Lilly dominate S&P Health Care index rankings with Quant scores of 3.47 and 3.44
• Artificial intelligence technology enables pharmaceutical companies to evaluate 50 times more drug candidates than traditional methods
• Individual opportunities emerge in companies like Intuitive Surgical, Natera, and Edwards Lifesciences amid broader sector recovery

A stealth rotation into healthcare equities is underway as institutional investors reposition portfolios away from overheated technology names. The convergence of defensive positioning and artificial intelligence breakthroughs is reviving interest in a sector that has languished for years.

Thursday’s trading session saw the Health Care Select Sector SPDR Fund climb 3%, simultaneously breaking through a critical short-term technical barrier. Market analysts interpret this price action as evidence of strengthening sector momentum.

Surging volume in managed care equities signals institutional capital allocation toward healthcare. After years of trailing the broader equity markets, this sector rotation represents a meaningful shift in investor sentiment.

The healthcare segment of the S&P 500 has declined 4% year to date, with projected full-year earnings expansion of merely 4%—the weakest among all sectors.

Political pressure on pharmaceutical pricing, declining Affordable Care Act participation, and Merck’s substantial one-time write-down have created sector headwinds. However, beneath these challenges, pockets of robust growth are emerging.

Artificial Intelligence Transforms Drug Development Pipelines

Pharmaceutical and biotechnology firms are deploying artificial intelligence systems to accelerate and economize drug candidate screening. Shivani Vohra, portfolio manager at Parnassus Investments, notes that computational models now perform tasks historically requiring laboratory personnel.

“Anywhere from five to 50 times the number of early-stage candidates are being looked at,” Vohra said. This technological leap enables companies to identify superior drug candidates with unprecedented efficiency.

This innovation represents a compelling reason for investors to look beyond near-term sector challenges.

Standout Equity Opportunities in Healthcare

[[LINK_START_1]]Eli Lilly[[LINK_END_1]] dominates the sector landscape. The pharmaceutical giant’s GLP-1 medications targeting obesity and diabetes are projected to generate approximately $22 billion in free cash flow this year, with forecasts reaching $47 billion by 2030. The stock currently trades at 31 times forward earnings.

Eli Lilly and Company, LLY

Intuitive Surgical manufactures the widely-adopted da Vinci robotic surgical platform, now considered essential infrastructure across hospital systems. The company is launching its first major platform upgrade in ten years, featuring enhanced computing capabilities and advanced imaging technology. Following a 25% decline over twelve months, shares trade at 40 times earnings.

Natera provides specialized blood diagnostics for prenatal care and oncology applications. Analysts project revenue will exceed $5 billion before decade’s end, more than doubling current levels, though profitability remains elusive.

Edwards Lifesciences is expanding beyond traditional heart valve replacement into emerging, high-growth valve therapy categories. The stock commands a 29 times earnings multiple.

Medline, which completed its public offering in December at $29 per share, recently traded below $35. The medical products supplier operates a private-label business model and trades at 23 times earnings.

Current Quant Rating Landscape

[[LINK_START_3]]UnitedHealth[[LINK_END_3]] and Eli Lilly command the top positions within the S&P Health Care index based on Quant Rating methodology, scoring 3.47 and 3.44 respectively. Both equities have recorded recent price appreciation.

Johnson & Johnson, Thermo Fisher Scientific, and Intuitive Surgical occupy subsequent ranking positions. Notably, no top-weighted holdings currently achieve a bullish Quant Rating exceeding 3.5, with the majority residing in neutral hold territory.

Abbott Laboratories registers the weakest performance score at 2.71, nearing bearish classification.

AbbVie, Gilead Sciences, and Abbott cluster at the lower end of sector rankings.

The overall sector profile suggests cautious optimism, with selective opportunities emerging as healthcare begins establishing a firmer foundation for sustained outperformance.

Bitcoin traded near $61,100 on Friday, wiping out about $335 million in leveraged long positions as the market wobbled through a sharp correction. The move followed a roughly 21% drop from the recent high and has traders recalibrating the risk of a sudden upside burst that could trigger a squeeze, given where short interest sits in the price band around $63,000 to $66,000.

Analysts estimate that a rally back toward $66,000 could threaten as much as $2.6 billion of open short positions, potentially igniting a faster-than-expected buyer response. Conversely, if BTC slides further to around $57,000, liquidations could total roughly $1.2 billion, underscoring the asymmetric risk in the current levered setup. The headline takeaway is that much of the risk is centered on a narrow corridor where bulls and bears bargain for control, and a decisive shift in either direction could reshape sentiment in days to come.

These dynamics unfold alongside a broader backdrop of spot Bitcoin ETF outflows and a fragile appetite for risk assets. In recent weeks, investors have pulled money from the Bitcoin ETF complex, with a 13-day streak of net outflows highlighted in prior coverage. The latest slice of data shows only a marginal $3 million net inflow on Thursday, insufficient to derail the ongoing liquidity drain that has seen about $5.1 billion leave the sector over the streak. This set of flows adds an extra layer of complexity for bulls hoping to stage a sustained comeback.

On the funding side, the market is painting a cautious portrait. BTC perpetual futures funding rates have turned negative, hovering around -2%. A neutral funding regime typically sits in the 6% to 12% annualized range, where longs pay to hold positions. The negative reading signals growing bearish conviction and a cooling of long-side leverage, which, in turn, dampens near-term upside risk even if spot prices flirt with key levels. In other words, bears appear to have a more comfortable position than in a strongly bullish backdrop, even as traders watch for a potential repricing higher.

Bitcoin’s underperformance relative to equities, particularly the Nasdaq 100, has underscored the fragility of the risk-on bid in recent sessions. The tech complex has shown signs of strain, with Broadcom (AVGO) closing down about 12.6% on Thursday and erasing roughly $280 billion in market value as investors digested a softer AI chip sales forecast for the second half of 2026. The disconnect between Bitcoin and tech strength adds nuance to the squeeze narrative: even if BTC can catch a bid, the broader market’s health remains a gating factor for sustained momentum.

Key takeaways

• Shorts concentrated near $63,000–$66,000 create a potential $2.6 billion squeeze risk if Bitcoin rallies toward $66,000.
• An additional 8% decline to roughly $57,000 could trigger about $1.2 billion in liquidations, underscoring downside risk if leverage remains intact.
• A move back to the $66,000 level could force the unwinding of a large share of short exposure, potentially reviving buyer interest after a prolonged ETF outflow phase.
• Negative BTC perpetual funding rates imply bears have momentum and are more willing to finance downside, reducing immediate upside risk for bulls.

Strategic rotation, macro cues, and what changes hands

The interplay between macro liquidity, sector rotation, and crypto-specific dynamics is guiding risk assessments. As AI mania has dominated headlines, capital has flowed into technology and AI-related equities and projects, leaving other corners of the market starved for liquidity. ParaFi Capital partner and Bitwise advisor Jeff Park captured the tension, saying the AI craze is drawing money away from other investments into what he described as a “hot ball of money” that everyone feels compelled to own. “Once this period of AI mania blows off, capital will rotate back to Bitcoin as its discounted valuation works in its favor,” Park observed.

Yet the near-term path remains nuanced. The market’s reliance on ETF inflows to sustain a meaningful rally is a live question. If spot ETFs begin to receive fresh inflows, the upside potential could widen, but that path remains contingent on broader liquidity conditions and regulatory guidance. In the meantime, observers highlight that a response from the ETF sector could act as a cap on downside risk or accelerate a relief rally, depending on whether outflows reverse or persist in the face of risk-off or risk-on shifts.

Some market commentators point to notable liquidity events that could act as turning points. Strategy’s leveraged Bitcoin model has recently faced its first stress test, with analyses noting that the framework could amplify volatility under certain conditions. In related coverage, observers flagged a recent 32 BTC sale by Strategy as a potential indicator of shifting provider balance sheets and risk tolerance. Such moves remind investors that large, strategic actors can influence short-term price action even as the market hunts for longer-term normalization.

For investors looking for a throughline, the rotation thesis remains central: AI sector enthusiasm could fade, and capital could rotate back into Bitcoin as the asset trades at a discount relative to risk-on assets and the broader market landscape stabilizes. The key question remains whether that rotation will take hold in time to cushion a test of resistance near $66,000 or whether the current momentum breaks further toward the low-$60,000s before buyers re-emerge.

What to watch next

Market participants should keep an eye on a few concrete developments that could tilt the balance over the next few sessions. First, ETF inflows or continued outflows will shape the supply-demand dynamics for spot Bitcoin and could either buttress a rally or deepen the pullback. Second, changes in perpetual funding rates—especially any sustained move back toward neutral or positive territory—would be a meaningful sign of shifting sentiment among leveraged traders. Third, macro precedents from the tech sector, including earnings or forecasts that recalibrate AI demand, will likely impact risk appetite more broadly and, by extension, Bitcoin’s trajectory.

As July approaches, traders will also be watching for narrative catalysts—regulatory developments, potential ETF approvals or changes, and notable liquidity events from a range of market participants. While a decisive move back to the $66,000 level is not guaranteed, the setup remains a reminder of how quickly leverage, sentiment, and macro flows can converge to create a volatile but potentially profitable window for those positioned to ride the squeeze dynamics if and when they unfold.

Source-linked data points and analyses cited above include CoinGlass for liquidation estimates, SoSoValue for ETF flow snapshots, Laevitas for funding rate data, and prior Cointelegraph coverage noting the ETF outflow streak. Related commentary on sector rotation and notable strategic trades is referenced from industry analysts and prior coverage of Strategy’s leveraged model and 32 BTC sale.

TLDR:

• Bitcoin has fallen below the median holder’s breakeven level for the first time since 2022.
• Glassnode data identifies the $46K-$54K range as the highest-probability Bitcoin bottom zone.
• The CVDD model near $46K has historically served as a reliable anchor during cycle lows.
• Bitcoin’s drawdowns are becoming shallower, supporting a higher floor than prior bear markets.

Where is the Bitcoin bottom? That question has gained urgency after Bitcoin fell to nearly $62,000, placing the asset about 50% below its all-time high.

The decline has pushed Bitcoin into a valuation range that has historically coincided with major cycle lows. According to market analyst Rafael, several long-term on-chain indicators now cluster around levels that previously acted as bear market floors.

While no model can identify an exact bottom in advance, current data offers a framework for assessing where support may emerge.

Bitcoin Approaches Historical Bottoming Levels

In a recent X thread, Rafael examined several valuation metrics used to identify potential cycle bottoms. He noted that Bitcoin has dropped below the median holder’s breakeven level for the first time since December 2022.

The analyst pointed to the Median Realized Price near $64,100 and the 200-week moving average around $61,700. Together, these metrics form an important support cluster that has attracted market attention.

According to the thread, Bitcoin has spent only about 7% of its history trading below the Median MVRV level. That makes the current price zone relatively uncommon compared with the broader trading history of the asset.

Rafael also outlined deeper support levels beneath the 200-week moving average. These include the Realized Price at roughly $54,000, CVDD near $46,000, Balanced Price around $40,000, and Delta Price close to $35,000. Previous bear market lows have typically entered this range before recovering.

Where Data Suggests the Bitcoin Bottom Could Form

The analysis places particular emphasis on the CVDD model. Rafael noted that across prior market cycles, Bitcoin’s ultimate lows frequently formed within a narrow range above the CVDD level.

According to the data, previous cycle bottoms generally occurred between 1.05 and 1.18 times the CVDD value. While other valuation metrics were occasionally breached, CVDD consistently served as a reliable anchor during major downturns.

With CVDD currently sitting near $46,200, the analyst identified a higher-probability bottom zone between $46,000 and $54,000. This range spans from the CVDD level to the Realized Price and represents the area where historical cycle floors have often developed.

Below that sits a deeper capitulation range between $35,000 and $40,000, defined by the Balanced Price and Delta Price models. Rafael noted that Bitcoin has traded in this lower zone during less than 3% of all trading days.

The analyst also observed that Bitcoin drawdowns have become progressively shallower over time. Earlier cycles recorded declines of approximately 85%, 84%, and 77%.

The current cycle has fallen around 50% from its peak. Although a deeper correction cannot be ruled out, the trend suggests the more likely Bitcoin bottom may reside within the $46,000 to $54,000 range rather than the lower capitulation zone.

Rafael stressed that no valuation model can predict an exact bottom. Instead, investors should view these levels as probability zones that help track changing market conditions.

For recovery, he identified the $75,000 to $79,000 region as the first major area Bitcoin would need to reclaim to signal improving market structure.

Hardcore bitcoin purists haven’t lost faith in the world’s largest digital currency, despite it losing nearly 17% of its value, marking the worst weekly performance since July 2024 and wiping out about $200 billion in market cap in the last seven days.

The prominent bitcoin advocates or maximalists (short for maxis) — a group that believes bitcoin is the only cryptocurrency likely to achieve lasting global adoption and monetary relevance — argue that capital is being sucked out of crypto and into artificial intelligence, creating what they see as a temporary liquidity crunch rather than a fundamental bitcoin problem.

This narrative comes as the world’s largest cryptocurrency is currently hovering below $60,000, down about 27% over the past month and down by more than 50% from its Oct. 6 all-time high, according to CoinDesk data.

The capital flight coincided with a record-breaking streak for U.S. spot bitcoin ETFs, which suffered $3.45 billion in outflows across 11 consecutive sessions. While crypto bleeds, Wall Street’s tech appetite remains aggressive. Even after the recent pullback, AI-related equities remain among the market’s strongest performers. The Nasdaq rose 34%, and the S&P 500 climbed nearly 24% in the last year, raising anxiety among crypto investors seeking answers about bitcoin’s underperformance.

While some market observers view the drop as a loss of structural confidence, bitcoin maxis argue the slump is merely a reflection of speculative capital rotating heavily into AI.

According to Mati Greenspan, a market analyst, bitcoin maximalist and founder of Quantum Economics, the price of bitcoin is in a downward trend, not because investors have lost faith in it, but because AI has become the dominant destination for speculative capital.

“Bitcoin is not facing a bitcoin problem. It’s facing a liquidity problem,” Greenspan told CoinDesk in an interview Friday. “AI has become the market’s new obsession, but obsessions fade.”

Another prominent bitcoin maxi and subject of recent debate if his bitcoin selling has caused the recent crash, Strategy (MSTR) Chairman Michael Saylor echoed Greenspan’s sentiment on X.

“Capital markets are funding the AI buildout at historic scale: ~$400B over six months,” Saylor said. Bitcoin ETFs have seen ~$4B of outflows since May 14, pressuring BTC. This is a capital rotation, not a bitcoin impairment. Volatility creates opportunity.”

‘The root cause’

Greenspan pointed to the Anthropic $50 billion IPO, targeting a nearly $1 trillion valuation, as the clearest indication of where market liquidity might have gone.

While bitcoin advocates point to the asset’s historical long-term returns, traditional liquidity pools are currently chasing AI infrastructure, data centers, and multi-billion-dollar private capital rounds, Greenspan added.

In fact, the anticipated IPOs of OpenAI, Anthropic and SpaceX, which together could raise more than $200 billion, may be drawing investor attention and capital toward AI and technology opportunities at the expense of other speculative assets, including crypto.

Bitcoin core developer and maximalist Jameson Lopp argued that investor frustration during market downturns often fuels the search for simple explanations. “I suspect the root cause is the bear market, combined with TradFi markets experiencing an AI boom,” Lopp said on X.

However, not everyone is blaming AI as the primary driver behind bitcoin’s weakness.

Market data suggests the pressure on crypto is multifaceted, and critics argue that blaming AI entirely oversimplifies a fragile macroeconomic environment. Jason Fernandes, a bitcoin maxi, market analyst and AdLunam co-founder, told CoinDesk that the asset is facing pressure from multiple fronts.

“BTC is under siege from every angle right now,” Fernandes said. “ETF outflows, high interest rates, creeping inflation, money rotating back into hot tech stocks, macro uncertainty, and now the psychological shock of Michael Saylor’s Strategy selling BTC after years of preaching ‘never sell.’”

Strategy, the largest publicly traded corporate holder of bitcoin, drew heavy criticism on social media after selling 32 bitcoin for $2.5 million in late May—its first sale in four years—to fund dividend payments on STRC, its perpetual preferred stock known as Stretch.

Though critics claimed the move “damaged confidence,” Greenspan, like many other analysts, dismissed the panic. “Selling 32 BTC against a balance sheet of more than 843,000 BTC is not even a rounding error,” Greenspan said.

Time to buy?

Despite the outflows, some of the maxis argue it might be time to dip into the underperforming asset as bitcoin’s longer-term fundamentals remain intact.

Greenspan argued that the recent record-breaking outflows from bitcoin funds are likely part of a rotation back toward monetary assets. He added that bitcoin’s current consolidation phase could serve as an accumulation zone if underlying network fundamentals hold. Despite the price dip, institutional adoption, regulatory frameworks, and discussions around bitcoin as a strategic reserve asset have continued to mature over the last few years.

Meanwhile, other bitcoin advocates, such as Strike CEO Jack Mallers, are bypassing broader market debates and encouraging investors to buy the dip on social media.

However, a rotation back into crypto is not guaranteed to be smooth. Even if bitcoin’s weakness stems partly from capital flowing into AI, Greenspan argues that a reversal may not immediately benefit crypto and might act as a double whammy.

“If AI sentiment cracks, bitcoin could get hit twice: first from liquidity leaving crypto, and then again from a broader risk-off move across markets,” Greenspan said.

“As for what comes next, I would be careful assuming the bottom is already in,” Greenspan noted.

Read more: Bitcoin isn’t crashing because of Saylor, it’s losing the momentum trade

TLDR:

• The U.S. added 172,000 jobs in May, nearly doubling forecasts and pushing rate hike odds to 57% in one day.
• Broadcom’s refusal to raise AI targets triggered a 12.6% stock drop, sparking fears of overvalued AI positions.
• SemiAnalysis reported Nvidia’s new chips need half the expected memory, sending SK Hynix and Samsung shares sharply lower.
• SpaceX, Anthropic, and OpenAI listings worth $4–$5 trillion are forcing fund managers to sell holdings to raise cash.

Global financial markets suffered a broad and sharp decline on Friday, erasing approximately $2.5 trillion in a single trading session.

The S&P 500 dropped 1.65%, while the Nasdaq fell 2.60%. Gold, silver, and Bitcoin also recorded steep losses. A combination of stronger-than-expected jobs data, cracks in the artificial intelligence trade, and looming liquidity concerns drove the widespread sell-off across asset classes.

Hot Jobs Report Rattles Rate Cut Expectations

The U.S. economy added 172,000 jobs in May, nearly double Wall Street’s forecast of 88,000. That surprise reading sent shockwaves through markets almost immediately after the open.

With inflation running at 3.8% and oil prices at $90 per barrel, the strong labor data changed the rate outlook sharply.

The probability of a Federal Reserve rate hike this year jumped from 40% to 57% in one session. Higher rates reduce the present value of future earnings, making growth and tech stocks less attractive. Investors responded by rotating out of those positions quickly.

As noted by market analyst account Bull Theory on X, “A labor market this strong tells the Fed it cannot cut interest rates and may actually need to raise them.” That shift in sentiment accelerated selling pressure across equity markets.

Adding to the uncertainty, new Fed Chair Kevin Warsh holds his first policy meeting in 11 days. Appointed under expectations of rate cuts, he now faces hot inflation, elevated oil, and a tight labor market. That uncertainty alone pushed many fund managers toward reducing risk.

AI Trade Cracks Under Pressure From Multiple Fronts

Broadcom reported record quarterly earnings, with revenue up 48% and AI chip sales climbing 143%. Yet the stock fell 12.6% after the company declined to raise its AI revenue targets. That single decision prompted investors to question whether AI valuations had grown too stretched.

Research firm SemiAnalysis then reported that Nvidia’s next-generation AI chips would require roughly half the memory previously priced into analyst models. SK Hynix fell nearly 10% on the news, while Samsung dropped over 6%. South Korea’s broader market declined 5.5% in a single session.

Anthropic also released a report warning that AI systems are approaching the ability to improve themselves without human input. The firm called for a global pause in AI development.

Coming alongside the chip memory news and Broadcom’s miss, it deepened fears about whether business models can sustain the current pace of AI growth.

Meanwhile, a liquidity drain looms over markets. SpaceX is set to go public next week at a $1.75 trillion valuation. Anthropic and OpenAI are also preparing listings.

Together, these three companies represent $4 to $5 trillion in potential capital demand. Fund managers are selling existing holdings to raise cash, adding further pressure to an already stressed market.