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Summit Therapeutics Inc. (SMMT) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Summit Therapeutics Inc. (SMMT) Goldman Sachs 47th Annual Global Healthcare Conference 2026 June 8, 2026 10:00 AM EDT

Company Participants

Allen Yang – Head of R&D Strategy
Robert Duggan – Co-CEO & Executive Chairman
Mahkam Zanganeh – Co-CEO, President & Director
Manmeet Soni – COO, CFO & Director

Conference Call Participants

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Salveen Richter – Goldman Sachs Group, Inc., Research Division

Presentation

Salveen Richter
Goldman Sachs Group, Inc., Research Division

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Great. Good morning, everyone. It’s my pleasure to introduce the Summit Therapeutics team. With us, we have Bob Duggan, Co-CEO with Maky Zanganeh, Co-CEO; Manmeet Soni, CFO; Allen Yang, CRDSO; and Dave Gancarz, CBSO.

Question-and-Answer Session

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Salveen Richter
Goldman Sachs Group, Inc., Research Division

To start here, a big picture question. Ivo is the leading PD-1 or L1 VEGF asset in development and China-based Phase III frontline lung cancer survival data was just recognized by the plenary at ASCO. Walk us through your overall strategy here, including across the various tumor types and combination approaches as you look to maintain your position and expand upon global development?

Allen Yang
Head of R&D Strategy

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Yes. We’re trying to keep that a little bit close to our chest because every time we announce something, our competitors announce the same thing and say we’re going to do it as well. But when we think about PD-1, VEGF, first of all, I think that PD-1 versus PD-L1 does make a difference. I don’t know if it changes too much your strategy, but it might change your overall baseline efficacy.

But with that said, 3 years ago, when we were looking at this asset, we did the boil the ocean exercise. We looked at all the PD-1 indications, all the VEGF approved indications. There was a lot of sort of history around those 2 targets that they are validated targets. And we looked at where

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Comparing the Tech Titans Shaping 2026

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Corning GLW Stock 2026 Outlook: Buy or Sell the AI

NEW YORK — As artificial intelligence reshapes industries and fortunes in 2026, two leaders stand out for their outsized influence: Elon Musk, the visionary behind Tesla, SpaceX and xAI, and Jensen Huang, the steady architect of Nvidia’s dominance in AI chips. While both have driven transformative technologies, their approaches, company scopes and personal impacts differ markedly.

Musk’s net worth has soared past $800 billion, fueled by SpaceX’s valuation nearing $2 trillion and Tesla’s continued leadership in electric vehicles and autonomy. Huang’s fortune hovers around $170-200 billion, tied closely to Nvidia’s record $5 trillion-plus market capitalization, making it the world’s most valuable company.

Musk operates a sprawling empire spanning electric vehicles, space exploration, neural interfaces and artificial general intelligence. His companies push boundaries in multiple domains simultaneously. SpaceX’s Starlink provides global broadband, Tesla advances sustainable transport and robotics, and xAI pursues fundamental understanding of the universe. This breadth gives Musk influence across transportation, energy, communications and computing.

Huang has focused Nvidia on a singular, explosive opportunity: graphics processing units that power modern AI. Under his leadership, Nvidia evolved from a gaming chip maker to the indispensable supplier of accelerators for data centers. The company’s CUDA software platform created a dominant ecosystem, while its Blackwell and future architectures set the pace for AI training and inference. Nvidia’s market cap surpassing $5 trillion underscores Huang’s success in capitalizing on the AI boom.

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Both leaders have distinct styles. Musk is known for bold, long-term bets and public engagement, often using social media to shape narratives around his ventures. Huang maintains a lower public profile, emphasizing technical excellence, customer partnerships and disciplined execution. Nvidia’s consistent delivery on roadmaps has earned Huang respect as a methodical operator who prioritizes engineering fundamentals.

In terms of immediate economic impact, Huang’s Nvidia holds the edge. Its chips are foundational to the current AI wave, powering everything from ChatGPT-like models to autonomous systems. Analysts credit Huang with foreseeing the shift to accelerated computing years before it became mainstream. Musk, meanwhile, bets on convergence: autonomous vehicles, humanoid robots and brain-computer interfaces that could define the next decade.

Wealth comparisons favor Musk decisively. His combined stakes across companies have pushed him toward trillionaire status, with SpaceX alone contributing hundreds of billions. Huang, while extraordinarily wealthy, remains more concentrated in Nvidia equity.

Influence extends beyond balance sheets. Musk’s ventures inspire public imagination and policy debates on space colonization, sustainable energy and AI safety. Huang’s work quietly powers the infrastructure enabling those ambitions, supplying the computational horsepower behind modern AI breakthroughs. Their occasional interactions, including text exchanges, highlight mutual respect in the AI ecosystem.

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For investors, both represent high-conviction technology bets. Nvidia offers exposure to the current AI infrastructure buildout with strong near-term visibility. Musk’s portfolio provides leveraged plays on multiple future technologies, albeit with higher execution and regulatory risks.

Challenges differ. Musk juggles multiple capital-intensive companies while navigating regulatory scrutiny and public controversies. Huang focuses on maintaining Nvidia’s technological lead against increasingly capable competitors and potential export restrictions.

Both CEOs have transformed their industries. Musk accelerated the global transition to electric vehicles and reusable rockets. Huang made GPUs the essential building block of AI, creating an entirely new computing paradigm. Their legacies will be measured not only by financial success but by societal impact.

Looking ahead, the AI race will test both leaders. Musk’s xAI and Tesla’s Dojo supercomputer pursue vertical integration, while Huang’s Nvidia supplies the foundational hardware. Their companies are interdependent yet competitive, creating a fascinating dynamic at the frontier of technology.

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Public perception splits along lines of admiration for audacity versus appreciation for steady execution. Musk embodies the charismatic innovator willing to tackle humanity’s biggest challenges. Huang represents the consummate engineer delivering reliable, scalable solutions that power the AI revolution.

In 2026, “bigger” depends on the metric. Musk leads in personal wealth, media presence and breadth of ambition. Huang leads in current market impact, consistent execution and direct enablement of the AI era. Both are indispensable to the technological future.

The comparison ultimately highlights complementary strengths. Musk pushes boundaries with visionary goals; Huang builds the foundational tools that make those goals feasible. Their parallel rises underscore how different leadership styles can drive progress in the same transformative era.

As AI reshapes economies and societies, the influence of both CEOs will likely grow. Investors, policymakers and technologists will continue watching their moves closely. Whether through bold leaps or methodical advancement, Musk and Huang exemplify the leadership required to navigate the complexities of rapid technological change.

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The coming years will reveal which approaches yield the most enduring impact. For now, their combined contributions have accelerated humanity’s AI journey, setting the stage for breakthroughs that will define the 21st century.

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Superior Plus Corp. (SPB:CA) Shareholder/Analyst Call Transcript

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Superior Plus Corp. (SPB:CA) Shareholder/Analyst Call May 13, 2026 4:00 PM EDT

Company Participants

David Smith
Darren Hribar – Senior VP & Chief Legal Officer
Chris Lichtenheldt – Vice President of Investor Relations
Allan MacDonald – CEO, President & Director

Presentation

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Operator

Hello, and welcome to the Annual Meeting of Shareholders of Superior Plus Corp. Please note that today’s meeting is being recorded. [Operator Instructions] It is now my pleasure to turn today’s meeting over to David Smith, Chair of the Board of Directors of Superior Plus. Mr. Smith, the floor is yours.

David Smith

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Ladies and gentlemen, good afternoon, and welcome to the 2026 Annual Meeting of the Shareholders of Superior Plus Corp. I am David Smith, and as Chair of the Board of Directors of Superior Plus, it is my responsibility and privilege to act as Chair of this annual meeting. Consistent with prior years and now common practice among other public companies in Canada, we are holding this meeting virtually via live audio webcast again this year. The virtual nature of this meeting has an impact on the way the meeting is conducted. Our goal is to preserve the rights of shareholders and proxy holders to vote on each of the resolutions before the meeting and to the extent possible, provide you with opportunities to participate in this virtual-only format similar to the way you would have at an in-person meeting.

As with any technology applications, unexpected issues may occur and Computershare, our service provider for this platform will help to resolve any issues that arise. I welcome our registered shareholders and all guests that are joining this meeting today through our virtual meeting platform. We’re excited to have your participation in the meeting, and thank you for your interest in the affairs of Superior Plus.

There is

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Voyager Technologies Is Set To Launch In 2027 And Beyond (Rating Upgrade)

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Voyager Technologies Is Set To Launch In 2027 And Beyond (Rating Upgrade)

Voyager Technologies Is Set To Launch In 2027 And Beyond (Rating Upgrade)

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Private sector banks are the best contrarian bet for the next 3 years, says S Naren

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Private sector banks are the best contrarian bet for the next 3 years, says S Naren
The continued rise in leverage among retail and high-net-worth investors through derivatives and margin trading facilities (MTFs) remains a key concern for the market, S Naren, Executive Director and CIO of ICICI Prudential AMC said at ICICI Securities India Investor Conference 2026.

While there has been significant discussion around the sustainability of mutual fund inflows and SIP contributions, Naren believes leverage in the derivatives market poses a much bigger risk than any moderation in mutual fund investments.

Also Read | Sensex down over 10K points from Dec peak. Should investors buy the dip, hold positions, or wait on sidelines?

“The level of leverage in the derivatives market and the amount of margin trading funding taken from brokers have continued to increase. That is a concern because leverage among retail and HNI investors is rising,” he said.

According to Naren, even if SIP inflows witness a marginal slowdown, it is unlikely to pose a significant challenge as mutual fund investors are typically long-term participants who invest without leverage. In contrast, derivative traders often operate with borrowed money, increasing risks during periods of market volatility.

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He noted that margin trading facility exposure is currently at its highest-ever level, highlighting the growing appetite for leveraged market participation.
Against this backdrop, Naren sees an interesting contrarian opportunity emerging in segments that have witnessed relentless foreign institutional investor (FII) selling over the last 20 months.”If you look for something contrarian today, it would be stocks where FIIs have been persistent sellers over the last 20 months,” he said.

Among these, private sector banks stand out as one of the most attractive investment opportunities for long-term investors, according to Naren.

He believes private banks could emerge as the best-performing sector over the next three years. One key reason is the significant reduction in foreign ownership resulting from sustained FII selling.

Also Read | Four mutual funds restrict large inflows into gold ETFs and FoFs; Rs 25 crore cap imposed

“FIIs used to have nearly 40% of their India portfolios allocated to private banks. Whenever they wanted to reduce exposure to India, private banks became the natural source of liquidity,” Naren explained.

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As a result, FIIs have consistently sold private banking stocks over the last 20 months, creating a valuation opportunity for long-term investors willing to take a contrarian view.

Beyond equities, Naren remains optimistic about India’s debt markets following recent policy measures aimed at improving foreign investor participation.

According to him, two critical factors that influence foreign investment in debt markets—currency stability and taxation—have both moved decisively in India’s favour.

“In debt, there are two factors: currency and taxation. Both have turned very positive, which significantly improves India’s attractiveness,” he said.

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Naren believes these developments improve India’s chances of gaining inclusion in global bond indices such as the Bloomberg Global Aggregate Bond Index and have contributed to a highly optimistic mood in the domestic debt market.

He pointed out that bond yields have moved well below policy rates in several segments, particularly in three-year corporate bonds, creating attractive investment opportunities.

However, Naren cautioned that the global fixed-income environment today is very different from what prevailed during the 2013 taper tantrum period.

At that time, interest rates across much of the developed world were close to zero, making India’s bond yields highly attractive to international investors. Today, investors can earn meaningful returns even in developed-market government bonds.

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“US 30-year government bonds are yielding around 5%, and even Japanese government bond yields are at levels not seen for decades,” he said.

As a result, the yield differential between India and developed markets has narrowed significantly compared with 2013.

Also Read | Gold and silver ETFs slip up to 8% amid Israel attack and crude oil spike. What should investors do?

While India has strengthened its macroeconomic position considerably over the past decade, global investors now have a wider range of attractive fixed-income options available to them.

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Naren also highlighted the relatively small size of foreign portfolio investor exposure to Indian debt compared with equities.

According to him, FPI debt investments remain only a fraction of FPI equity allocations. In contrast, foreign investors had built substantial equity positions in India during a period when domestic valuations traded at significant premiums to other emerging markets.

He noted that Indian equities became exceptionally expensive after 2023 as domestic investors increasingly channelled savings into equities rather than debt.

“Valuations in India reached levels that were several times higher than markets like China. In such an environment, FIIs logically chose to reduce equity exposure,” he said.

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At the same time, India has historically adopted a cautious approach towards opening its debt markets to foreign investors.

Naren believes this measured approach has helped preserve financial stability while gradually increasing foreign participation in government securities.

With improving debt market fundamentals, supportive policy measures, and attractive opportunities emerging in sectors overlooked by foreign investors, Naren sees both fixed income and select equity segments offering compelling opportunities for long-term investors.

Commenting on the recent correction in Kospi, Naren said that it is a healthy correction but even now I don’t think on market cap terms it is cheap.

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(Disclaimer: Recommendations, suggestions, views and opinions given by the experts are their own. These do not represent the views of The Economic Times)

If you have any mutual fund queries, message on ET Mutual Funds on Facebook/Twitter. We will get it answered by our panel of experts. Do share your questions on ETMFqueries@timesinternet.in alongwith your age, risk profile, and Twitter handle.

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Major Events in Politics, Economy, Tourism, and Society

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Major Events in Politics, Economy, Tourism, and Society

Thailand is tightening tourist visa-free stays for over 90 nations due to visitor misconduct. Thailand is pursuing UN maritime arbitration with Cambodia over border disputes. Domestically, the government is advancing a smog reduction bill, launching a THIM app for foreign arrivals, and exploring an automation tax amid AI-driven job concerns. Tourism remains active with promotions at Amsterdam’s Amazing Thailand Fest. Tragic incidents include a monkey attack killing a child and a couple’s fatal hotel jump. Thailand also discovered Southeast Asia’s largest dinosaur.

Thailand in Focus: A Comprehensive News Roundup

Tourism and Visa Policy Changes

Thailand has made significant changes to its visa-free entry policy, reducing the permitted stay duration for visitors from over 90 countries, including the United States, from 60 days to a shorter period. The decision was driven by concerns over tourist misbehavior and misuse of visa-free privileges. South China Morning Post | The New York Times

The country continues to actively promote itself on the global stage. The Amazing Thailand Fest 2026 in Amsterdam showcased Thai culture, cuisine, and wellness tourism, attracting significant European interest. Thailand also participated in TTM+ 2026, emphasizing wellness-focused journeys, responsible travel, and new destination opportunities as part of its broader quality tourism strategy. Travel and Tour World | Nation Thailand

To manage the influx of visitors more effectively, Thailand is preparing the THIM app, a digital registration tool for foreign arrivals set to launch before August. The initiative reflects the government’s push to modernize border management and improve traveler tracking. Nation Thailand | The Economic Times

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Safety, Crime, and Legal Matters

A 6-year-old boy died in Thailand after being attacked by his grandfather’s pet monkey, highlighting ongoing concerns about exotic animal ownership in the country. The monkey was subsequently released following the fatal incident. South China Morning Post

In a tragic case linked to financial hardship, a married couple reportedly held hands and jumped from a hotel balcony in Thailand, reportedly overwhelmed by crippling debts. The incident drew widespread attention to the mental health and economic pressures facing residents. Mothership

Ten Israelis were deported from Thailand as part of an ongoing crackdown on foreign-linked criminal activity. Separately, Thai police detained a suspected Cambodia-based fraud ringleader, and the Thailand Consumers Council filed lawsuits against four global platforms, including Facebook, over scam advertisements and inadequate victim redress. The Times of Israel | Nation Thailand

A Thai criminal court acquitted a political leader of lèse-majesté charges, a notable legal development in a country where such cases are closely watched by civil society and international observers. Jurist.org

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Diplomatic and Geopolitical Developments

Thailand announced it will join a UN-backed maritime conciliation process with Cambodia to resolve a long-standing border dispute, while halting other bilateral talks. Cambodia has also formally launched the UN-backed process, with the Phnom Penh Post urging sincerity in resolution efforts. Reuters | The Diplomat

On the northern border, Malaysia and Thailand are stepping up cooperation on flood control and water security along the Sungai Golok river, reflecting growing bilateral infrastructure collaboration. Thailand’s Prime Minister Anutin also met with Thai-Vietnamese businesses to drive broader ASEAN economic growth. Malay Mail | Nation Thailand

A US Embassy health alert was issued regarding enhanced Ebola screening in Thailand, urging American citizens to take precautions. Meanwhile, Thailand confirmed there was no domestic impact from a tsunami warning triggered by a Mindanao earthquake. U.S. Embassy Thailand | Nation Thailand


Economy, Technology, and Investment

Thailand is positioning itself as ASEAN’s data center capital, with the country’s richest man planning to invest US$4.3 billion to build data centers with capacity up to 2,000MW. However, the World Bank has flagged cost risks if Thailand’s broader digital economy development lags behind expectations. W.Media | Nation Thailand

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The Thai payments sector is forecast to grow at a 36% compound annual growth rate through 2032, signaling strong momentum in financial technology. Thailand is also considering an automation tax as artificial intelligence threatens millions of jobs, reflecting forward-looking but cautious economic policymaking. Asian Banking & Finance | HRM Asia

Thailand’s private sector has been called upon to lead post-Hormuz Strait disruption recovery, with Nikkei Asia noting the urgency for business-led resilience strategies. Former Prime Minister Thaksin Shinawatra may face bankruptcy proceedings over a $538 million tax debt, according to Bloomberg. Nikkei Asia | Bloomberg

Thailand’s IMF-World Bank 2026 hosting role is seen as a golden opportunity to attract foreign investment and elevate the country’s global economic profile. Nation Thailand


Environment and Society

Northern Thai residents marched to demand urgent action on polluted rivers, describing the situation as an environmental emergency. Separately, Thailand revived a key legislative bill aimed at addressing the country’s severe toxic smog problem, which has long plagued northern regions. Mongabay | DW

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Thailand donated 12.4 tonnes of rice to the World Food Programme to support food-insecure communities in northeastern Nigeria, reinforcing its commitment to international humanitarian efforts. Khaosod English

In a landmark paleontological discovery, Southeast Asia’s largest dinosaur was found in Thailand — a sauropod from the Lower Cretaceous Khok Kruat Formation, enriching global understanding of titanosauriform diversity in the region. South China Morning Post | Nature


Culture, Media, and Sports

Thailand launched the Bangkok International Content Market, positioning the capital as a major hub for Asia’s creative and entertainment industries. The initiative signals Thailand’s ambitions beyond traditional tourism into the global content economy. The Hollywood Reporter

PUBG Global Series Circuit 2 2026 saw Thai team “Made in Thailand” dominate the competition with a convincing victory, boosting national pride in the growing esports sector. Thailand also prepared for a volleyball nations league clash against the Czech Republic in Nanjing. Gamereactor UK

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Thailand scrapped its 54-year-old daytime alcohol sales ban, a significant cultural and regulatory shift likely to affect both domestic consumers and the hospitality and tourism industries. Thailand also imposed stricter airport rules on power bank safety, aligning with international aviation standards. Seoul Economic Daily | Travel and Tour World

Source : Google News – Search

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US stocks: S&P 500, Nasdaq end up as tech, chipmakers rebound

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US stocks: S&P 500, Nasdaq end up as tech, chipmakers rebound
U.S. stocks ended mostly higher on Monday, led by gains in the Nasdaq and chipmakers as investors sought bargains after Friday’s sharp selloff and were relieved after Iran and Israel said they had halted attacks on each other.

The halt came after an appeal from U.S. President Donald Trump that they immediately “stop shooting.” The attacks over 24 hours were the most ‌direct confrontation between ⁠Iran and ⁠Israel since an April ceasefire in the war. The Dow ended lower and stocks overall closed off the highs of the day. Apple shares eased late in the session even as the company unveiled a series of AI upgrades to Siri. The S&P 500 technology sector and Philadelphia SE Semiconductor Index advanced, rebounding from Friday’s losses that wiped out $1 trillion in market value for U.S.-listed chipmakers. Intel shares also jumped after news website the Information reported that Alphabet’s Google had placed an order to manufacture more than 3 million tensor processing units in 2028.

“Today looks like a day where investors are doing a little bit of bargain hunting ⁠off the ‌big tech selloff,” said Rick Meckler, partner at Cherry Lane Investments, a family investment office in New Vernon, New Jersey. “What normally happens after that is you get analysts coming in and reiterating buys.”

He added: “This market has ⁠been priced for quite a while for perfection, and these are certainly imperfect times. In that environment, you are going to see some back-and-forth, and some fear of prices having gone too far.” Stocks sold off late last week after hitting a series of record highs recently. Underwhelming results from chipmaker Broadcom last week had raised concerns that the chip sector was growing too fast, while much stronger than expected jobs data for May contributed to Friday’s rout, as traders priced in interest rate increases this year.

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According to preliminary data, the S&P 500 gained 22.07 points, or 0.30%, to end at 7,405.81 points, while the Nasdaq Composite gained 222.13 points, or 0.86%, ‌to 25,931.56. The Dow Jones Industrial Average fell 75.61 points, or 0.15%, to 50,791.17.


Also Read | US stocks: Alphabet taps Intel to make three million in-house chips: Report
Apple announced the Siri revamp at its annual Worldwide Developers Conference at its Cupertino, California, headquarters. Investors may be having a “sell-on-the-news” response, said Bruce Zaro, managing director at Granite Wealth Management in Plymouth, Massachusetts.

“Perception has ⁠been for quite some time that Apple had been behind the curve as far as their AI offerings. That’s why the stock widely underperformed many of the other big techs for some time until recently,” he said. SpaceX’s initial public offering on Friday could also prove a major test for U.S. stock markets, with investors wary of possible overexuberance. Other big tech advancers included Marvell Technology, which jumped as the chipmaker was set to join the benchmark S&P 500 before the start of trading on June 22. Eli Lilly gained after the drugmaker’s trial results showed its next-generation obesity drug, retatrutide, curbed sleep apnea severity in addition to boosting weight loss and helping knee pain.

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McDonald’s outlines new strategic course

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McDonald’s outlines new strategic course

McDonald’s Next includes menu innovation and in-store technology.

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Tango Therapeutics, Inc. (TNGX) Discusses Promising Clinical Results for Vopimetostat and Pan-RAS Inhibitor Combination in MTAP-Deleted Pancreatic Cancer Transcript

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Tango Therapeutics, Inc. (TNGX) Discusses Promising Clinical Results for Vopimetostat and Pan-RAS Inhibitor Combination in MTAP-Deleted Pancreatic Cancer June 8, 2026 8:00 AM EDT

Company Participants

Elizabeth Hickin
Malte Peters – President, CEO & Director
Adam Crystal – President of Research & Development
Matthew Gall – Chief Financial Officer

Conference Call Participants

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Brian Wolpin
Eric Schmidt – Cantor Fitzgerald & Co., Research Division
Michael Schmidt – Guggenheim Securities, LLC, Research Division
Laura Prendergast – Stifel, Nicolaus & Company, Incorporated, Research Division
Kelsey Goodwin – Piper Sandler & Co., Research Division
Joseph Catanzaro – Mizuho Securities USA LLC, Research Division
Andrew Berens – Leerink Partners LLC, Research Division
John Newman – Canaccord Genuity Corp., Research Division
Maurice Raycroft – Jefferies LLC, Research Division
Yuan Zhi – B. Riley Securities, Inc., Research Division
Kalpit Patel – Wolfe Research, LLC
Robert Driscoll – Wedbush Securities Inc., Research Division

Presentation

Operator

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Good day, and welcome to the Tango Therapeutics conference call. [Operator Instructions] Please note, this call is being recorded. I’d now like to turn the call over to Liz Hickin, Vice President, Investor Relations and Corporate Communications. Please go ahead.

Elizabeth Hickin

Thank you, and good morning, everyone, and thank you for joining us on today’s call. This morning, we issued a press release on the data, which can be found on the Investors and Media section of our website, www.tangotx.com. Before we begin, let me review our safe harbor statement. We will be making forward-looking statements on this call that are subject to risks and uncertainties discussed in detail in today’s press release and in our filings with the Securities and Exchange Commission. This call is being recorded, and a replay will be available on our website.

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The agenda for this morning’s call is as follows: Malte Peters, Tango’s President and CEO, will share some introductory remarks. We are pleased to be joined today by Dr. Brian Wolpin, Director

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Syndax Pharmaceuticals, Inc. (SNDX) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Syndax Pharmaceuticals, Inc. (SNDX) Goldman Sachs 47th Annual Global Healthcare Conference 2026 June 8, 2026 2:00 PM EDT

Company Participants

Michael Metzger – CEO & Director
Keith Goldan – CFO, Treasurer & Principal Accounting Officer

Conference Call Participants

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Corinne Jenkins – Goldman Sachs Group, Inc., Research Division

Presentation

Corinne Jenkins
Goldman Sachs Group, Inc., Research Division

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All right. Good afternoon, everyone, thanks again for joining us at the Goldman Sachs Global Healthcare Conference. We’re thrilled to have Michael Metzger; and Keith Goldan, Chief Executive and Chief Financial Officer for Syndax here with us this afternoon. And maybe we’ll just kick it off some high-level questions.

First, how do you think about the core competencies of Syndax. And how does that inform kind of your strategic priorities for the business over the near term?

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Question-and-Answer Session

Michael Metzger
CEO & Director

First of all, thank you, Corrine for inviting us here today, great opportunity to be in front of this audience. So Syndax is in a great position as a company. You mentioned our core competencies. We’ve been able to bring two drugs all the way through development and get them approved and certainly launched them in the last year plus has been very successful for the company. That kind of informs our core competencies. I would highlight R&D and the ability to translate early science into products of meeting and bringing them all the way through development.

So the R&D capabilities of Syndax are quite strong, gotten more robust over time. So that is something we lean on significantly to advance our medicines and really differentiate in the marketplace. And then, of course, the commercialization competency within hem today, we think is differentiating for us as we’ve advanced both of our medicines and they’re both hem medicines to bring them to as many patients as possible. So

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(PHOTO) Jessica Alba Stuns Fans With Glamorous Miami Throwback Post on Instagram

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Jessica Alba

NEW YORK — Jessica Alba, the actress and entrepreneur known for her roles in “Dark Angel” and the “Fantastic Four” films, delighted followers on Instagram with a glamorous Miami-themed post that showcased her enduring style and sparked widespread admiration.

In the post shared on her verified account, Alba captioned a striking image “That Miami glam just hits different #FBF,” referring to a #FlashbackFriday moment. The photo, featuring Alba in elegant attire with a confident pose against a vibrant Miami backdrop, quickly garnered thousands of likes and comments praising her timeless beauty and graceful aging.

Fans flooded the comments section with enthusiastic responses. Many highlighted Alba’s appearance, with remarks such as “Jessica, you get Hotter with age” and “The most beautiful one.” Others expressed awe at her poise, noting “I looked up ‘aging backwards’ on Google and your pic came up. My goodness.” The post resonated widely, reinforcing Alba’s status as a enduring figure in entertainment and beauty.

Alba, 45, has successfully transitioned from acting to entrepreneurship. She co-founded The Honest Company in 2011, a consumer goods brand focused on safe, eco-friendly products for families. The company went public in 2021 and has expanded into multiple categories, including personal care, cleaning and baby products. Alba’s commitment to transparency and sustainability has earned her recognition as a business leader.

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Beyond The Honest Company, Alba remains active in entertainment. She has appeared in recent projects and continues to engage with fans through social media, offering glimpses into her family life, wellness routines and professional endeavors. Her Instagram presence often blends personal moments with promotional content for her brand and causes she supports.

The Miami post taps into Alba’s history with the city, where she has spent time for both work and leisure. Miami’s vibrant culture, beaches and fashion scene have long inspired her style, and the #FBF tag suggests a nostalgic reflection on past experiences in the city. Such posts humanize celebrities, allowing fans to connect with their idols beyond red carpets and film roles.

Alba’s approach to social media emphasizes positivity, family and empowerment. As a mother of three, she frequently shares insights on parenting, wellness and balancing career demands. Her openness about mental health and the challenges of public life has resonated with many followers, fostering a supportive online community.

Industry observers note that Alba’s enduring appeal stems from her versatility. From action roles in her early career to business leadership, she has reinvented herself while maintaining authenticity. Her beauty and fashion influence remain strong, with fans often citing her as an example of graceful aging and confidence.

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The Instagram post’s virality highlights the power of celebrity social media in 2026. Platforms like Instagram continue to serve as direct channels for stars to engage audiences, bypassing traditional media filters. Alba’s strategic yet personal sharing style has helped sustain her relevance long after her peak acting years.

Comments on the post also touched on broader themes of beauty standards and self-acceptance. Many users praised Alba for embracing her natural look and inspiring confidence in women of all ages. The outpouring of positive messages reflects her role as a relatable figure who balances glamour with grounded perspectives.

Alba’s business ventures extend beyond The Honest Company. She has invested in wellness and lifestyle brands, leveraging her platform to promote products aligned with her values. Her entrepreneurial success demonstrates how celebrities can build lasting legacies outside traditional entertainment.

As Alba continues evolving her career, moments like the Miami post remind fans of her multifaceted identity. Whether sharing family snapshots, business updates or glamorous throwbacks, she maintains a connection that feels genuine and aspirational.

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The timing of the post coincides with a busy period for Alba. With The Honest Company expanding its footprint and potential acting projects on the horizon, she balances professional demands with personal fulfillment. Her social media activity often serves as a window into this balance, offering inspiration to followers navigating similar challenges.

Miami itself holds special significance for many celebrities, serving as a hub for entertainment, business and leisure. Alba’s reference to its “glam” captures the city’s vibrant energy and aesthetic appeal, resonating with fans familiar with its allure.

Social media reactions extended beyond simple compliments. Some users shared personal stories of empowerment inspired by Alba’s journey, while others expressed admiration for her business acumen and commitment to family. The post’s engagement underscores her continued cultural relevance.

As one of Hollywood’s enduring talents, Alba exemplifies successful navigation of fame’s complexities. Her transition from actress to entrepreneur and advocate sets an example for future generations of performers seeking multifaceted careers.

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The Miami glam post, while lighthearted, contributes to a larger narrative of gratitude, resilience and celebration of life’s moments. In an era of constant digital connection, such shares foster community and remind audiences of the human side behind celebrity personas.

Alba’s influence extends to younger audiences who discover her through family-friendly roles or beauty brand campaigns. Her emphasis on authenticity and kindness provides a positive counterpoint to more controversial aspects of celebrity culture.

As reactions continue pouring in, the post solidifies Alba’s position as a beloved figure who bridges entertainment, business and personal inspiration. Whether through acting, entrepreneurship or simple social media moments, she continues captivating audiences with grace and relatability.

The Instagram update serves as a timely reminder of Alba’s star power and the affection she commands from fans worldwide. As she navigates new chapters in her career and life, moments like this Miami glam throwback keep her connected to supporters who have followed her journey for decades.

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