Mistake when taking the medication could lead to two different conditions
Omeprazole is a common medication taken by millions of people across the UK to treat a range of stomach issues like heart burn, indigestion and acid reflux. However, many people could be ‘misusing’ the drug because it’s available over-the-counter with few understanding the warnings around how long they are allowed to take it.
Researchers in Brazil discovered that using Omeprazole for too long can change the way your body absorbs certain nutrients, potentially putting people at risk of serious health issues like aneamia and osteoporosis by decreasing iron levels and leeching calcium from your diet into the bloodstream instead of your bones.
Osteoporosis causes the bones to become more weak and fragile, making it more susceptible to breaks and fractures as they start losing bone density. It develops over several years but the condition doesn’t have many noticeable symptoms until a person starts breaking bones.
Anaemia on the other hand causes a range of noticeable symptoms including tiredness, shortness of breath, heart palpitations, pale skin and headaches. It can be treated with certain medications and lifestyle changes such as eating more meat and fortified cereals.
Official guidance from the NHS warns: “Do not take omeprazole for longer than 2 weeks if you bought it without a prescription. See a GP if your symptoms get worse or do not get better.”
However, because people can buy some omeprazole medications at pharmacies without needing a prescription, some may be taking it for much longer than they are meant to.
People taking the medication long-term are advised to have regular check-ins with their doctor. It’s also best to check with your doctor if you plan to stop taking the drug after long-term use, even if it wasn’t prescribed in the first place.
Omeprazole can cause a range of side effects even with normal usage under doctor’s orders. This can include headaches, stomach pain, nausea, constipation, diarrhoea or vomiting.
The NHS also warns: “Taking omeprazole can make it harder to notice symptoms of some serious conditions, such as stomach cancer. See a GP if you’re worried.”
Published in the ACS Omega journal earlier this year, scientists at the Federal University of São Paulo (UNIFESP), the study used rates and simulated the way humans use the drug. They found long-term use caused mineral accumulations in the stomach, imbalances in the spleen and liver as well as changes in the blood.
The animals’ blood had increased calcium levels and decreased iron levels. Indicating a risk of anemia and osteoporosis as a result. Longer studies are needed to confirm these results.
Andréa Santana de Brito, a researcher at UNIFESP, told Agência FAPESP: “It isn’t a question of demonizing the drug, which is effective for various gastric conditions. The problem is its trivialized use, even for mild symptoms such as heartburn, and for prolonged periods of months and even years. Its adverse effects shouldn’t be overlooked.”



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