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Nurix Therapeutics, Inc. (NRIX) Presents at RBC Capital Markets Global Healthcare Conference 2026 Transcript

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Nurix Therapeutics, Inc. (NRIX) RBC Capital Markets Global Healthcare Conference 2026 May 20, 2026 1:30 PM EDT

Company Participants

Arthur Sands – CEO, President & Director
Jason Kantor – Chief Business Officer

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Conference Call Participants

Brian Abrahams – RBC Capital Markets, Research Division

Presentation

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Brian Abrahams
RBC Capital Markets, Research Division

So let’s get started. Good afternoon, everyone. Welcome back from lunch. I’m Brian Abrahams, senior biotech analyst here at RBC Capital Markets. We’re really pleased to have our next featured company, Nurix Therapeutics, represented by their CEO, Arthur Sands and their CBO, Jason Kantor.

Arthur Sands
CEO, President & Director

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Great. Good to be here. Thanks, Brian.

Question-and-Answer Session

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Brian Abrahams
RBC Capital Markets, Research Division

Thanks for being here. So maybe let’s start a little bit bigger picture on your lead program, Bexdeg. Tell us what your latest view is on the potential advantages that BTK degraders can have in the CLL space relative to the currently available inhibitors, what’s out there today? And what’s been your view as to the strongest preclinical and clinical evidence and data to date that’s really helped support that? And I know the data is continuing to evolve. So I would love to hear your latest views on that.

Arthur Sands
CEO, President & Director

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Yes, excellent question. The advantage of targeted protein degrader in this space in CLL and in BTK, we’re seeing advantages expand and grow. So I can tell you where we started and now where we think it is, which is quite exciting.

So we started with the concept that by removing the protein, we could address certain BTK inhibitor resistance mutations, which were just emerging, if you go back to the beginning of, let’s say, 2020, 2019. So the concept that by degrading the protein through the ubiquitous proteasome system, we could address this emerging problem

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Wordle Answer for May 22 2026 Revealed as VOCAL in Puzzle 1798

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Air travellers wearing a protective face masks, amid the coronavirus disease (COVID-19) pandemic, at JFK International airport in New York

NEW YORK — The New York Times Wordle puzzle for Friday, May 22, 2026, is No. 1,798, with the solution “VOCAL,” an adjective that challenged many players with its combination of common and less frequent letters.

Players had six attempts to guess the five-letter word. Feedback used colored tiles: green for correct letters in the right position, yellow for correct letters in the wrong position, and gray for letters not in the word.

According to The New York Times Wordle Review, today’s word is VOCAL. It means “having a voice; capable of speaking or making oral sounds,” per Webster’s New World College Dictionary.

The puzzle took testers an average of around 4.2 guesses. Many players solved it in three or four attempts, though some needed five or six due to the vowel placement and the less common “V” starting letter.

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Yesterday’s answer for puzzle No. 1,797 on May 21 was AGREE.

Wordle, created by Josh Wardle and acquired by The New York Times in 2022, continues to attract millions of daily players worldwide. The game resets at midnight local time and offers one unique puzzle per day with no repeats.

Hints for today’s puzzle included a subtle clue pointing toward something related to voice or sound. It featured common vowels with “O” and “A” and started with “V.” Common starting words such as AUDIO, ADIEU or VOICE helped many players narrow down possibilities quickly.

The game’s simple yet engaging mechanics have sustained its popularity since its public launch. Sharing results on social media using emoji grids remains a popular daily ritual among fans.

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Wordle maintains a dedicated following across age groups. Players praise its blend of vocabulary knowledge, deduction and luck. The New York Times publishes official hints and the full review daily after the puzzle launches.

For those who missed today’s solution, VOCAL fits common English usage in contexts of speaking, singing or expressing opinions. It appears frequently in both everyday conversation and formal writing.

The Times does not publish past answers directly but archives reviews that confirm solutions once the day passes. Independent sites and apps often compile historical lists for reference.

Community discussions on platforms like Reddit’s r/wordle featured thousands of posts sharing scores for puzzle 1,798. Many celebrated three-guess solves, while others analyzed near-misses involving words like VOCAL’s close alternatives such as VITAL or LOCAL.

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Wordle’s difficulty fluctuates based on letter frequency and word commonality. VOCAL ranked as moderately challenging due to the starting “V” and vowel pattern.

The New York Times has introduced companion games including Connections, Strands and Mini Crosswords, expanding its daily puzzle ecosystem. Wordle remains the flagship title.

Players seeking to improve often study vowel distributions and common consonant clusters. Resources include word frequency lists and elimination strategies that avoid repeating gray letters.

Global participation spans time zones, with players in Asia often solving first each day. Streaks remain a popular personal challenge, with dedicated users maintaining hundreds of consecutive solves.

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The game’s code limits solutions to a curated list of approximately 2,300 words, avoiding obscure terms while maintaining fairness. Official reviews provide etymology and definitions post-solve.

For May 22, 2026, VOCAL joins recent answers including AGREE on May 21. Archives show patterns in vowel-heavy or consonant-balanced selections.

Educators sometimes incorporate Wordle into classrooms to build vocabulary and reasoning skills. Its accessibility requires no downloads, only a web browser.

Mobile users access the same puzzle via nytimes.com or the dedicated Games app. Dark mode and high-contrast options support broader accessibility.

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As of midday May 22, discussions continued online with players comparing strategies and celebrating streaks preserved by VOCAL. Some noted the word’s relevance to singing and expression fitting current cultural conversations.

Tomorrow’s puzzle, No. 1,799 for May 23, will introduce a fresh challenge at midnight. Players are advised to avoid spoilers until attempting their own solve.

Wordle’s enduring appeal lies in its daily rhythm and communal experience. Whether solved in two guesses or six, it delivers a small moment of linguistic satisfaction for participants worldwide.

The solution VOCAL for puzzle 1,798 underscores the game’s balance of approachability and occasional difficulty spikes. Official hints and community tips help maintain engagement across skill levels.

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SpaceX: What Does History Tell Us About Investing In The Biggest IPOs? I Am Cautiously Optimistic

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NYT Connections Puzzle 1076 Solved for May 22 2026 with Conveyor Belts and Homophones

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Nancy Guthrie

NEW YORK — The New York Times Connections puzzle No. 1,076 for Friday, May 22, 2026, challenged players with 16 words grouped into four categories featuring ways to reach back out, social conventions, places with conveyor belts and words starting with name homophones.

The 16 words in today’s grid were: CHECK IN, FOLLOW UP, RECONNECT, TOUCH BASE, CONVENTION, CUSTOM, SOCIAL NORM, UNWRITTEN RULE, ASSEMBLY LINE, BAGGAGE CLAIM, CHECKOUT LANE, REVOLVING SUSHI BAR, CARRY-ON, EL NIÑO, LOOSEY-GOOSEY, TAILOR-MADE.

The yellow category, typically the easiest, was “Reach back out”: CHECK IN, FOLLOW UP, RECONNECT, TOUCH BASE.

The green category was “The way things are done”: CONVENTION, CUSTOM, SOCIAL NORM, UNWRITTEN RULE.

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The blue category was “Places with conveyor belts”: ASSEMBLY LINE, BAGGAGE CLAIM, CHECKOUT LANE, REVOLVING SUSHI BAR.

The purple category, often the most difficult, was “Starting with name homophones”: CARRY-ON, EL NIÑO, LOOSEY-GOOSEY, TAILOR-MADE.

Connections, created by Josh Wardle and acquired by The New York Times, presents 16 words daily that must be sorted into four groups of four sharing a common theme. Players receive feedback with colored tiles progressing from yellow (easiest) to green, blue and purple (hardest).

The puzzle resets at midnight local time. Players have four mistakes allowed before the game ends. Many shared scores on social media using emoji grids showing their solve path.

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Community discussions on Reddit’s r/NYTConnections highlighted the cleverness of the purple category, which relied on homophones of names (Carrie, Elle, Lucy, Taylor). The blue category referencing conveyor belts, including the revolving sushi bar, drew comments for its specificity.

Yesterday’s puzzle on May 21, 2026, was No. 1,075. The May 22 edition followed the standard format without additional twists.

The New York Times publishes a Connections Companion article daily with hints and community conversation. For puzzle 1,076, the companion noted the mix of everyday phrases and more niche cultural references.

Players often start by identifying obvious connections, such as the reach-back-out phrases in the yellow group. The conveyor belt locations required knowledge of practical settings where items move continuously.

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The homophone category tested wordplay skills, with CARRY-ON (Carrie), EL NIÑO (Elle), LOOSEY-GOOSEY (Lucy) and TAILOR-MADE (Taylor).

Forbes and other sites provided pre-solve hints: the yellow group referenced communication after absence; the green group linked to societal expectations; the blue group involved moving items; and the purple group played on name sounds.

Difficulty varied. Some solvers completed it quickly by spotting the conveyor belt and social norm groups, while others struggled with the purple category until eliminating other possibilities.

The game encourages logical deduction and word association. Strategies include scanning for proper nouns, brand names, homophones or thematic clusters like social phrases, locations and wordplay.

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Connections has grown in popularity alongside Wordle, Strands and other New York Times Games. It attracts a broad audience seeking a daily mental workout combining vocabulary, general knowledge and pattern recognition.

No repeats occur in the curated word list. Editors select groupings to balance accessibility with challenge, occasionally drawing from cultural references that resonate differently globally.

Tomorrow’s puzzle, No. 1,077 for May 23, 2026, will offer a new set of 16 words at midnight. Players are encouraged to attempt solves independently before checking solutions.

Educational uses include classroom activities for building categorical thinking and cultural literacy. The game’s web and app accessibility supports play across devices.

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As of midday May 22, online forums continued discussing solve strategies and near-misses for puzzle 1,076. Common mistakes involved mixing communication phrases with social norms or confusing conveyor locations.

The New York Times Games team curates Connections to maintain engagement. Puzzle 1,076 exemplified the blend of straightforward and clever connections that defines the daily experience.

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QLTY: High Quality Does Not Guarantee Outperformance, Hold Rating Maintained

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This article was written by

Vasily Zyryanov is an individual investor and writer.He uses various techniques to find both relatively underpriced equities with strong upside potential and relatively overappreciated companies that have inflated valuation for a reason.In his research, he pays much attention to the energy sector (oil & gas supermajors, mid-cap, and small-cap exploration & production companies, the oilfield services firms), while he also covers a plethora of other industries from mining and chemicals to luxury bellwethers.He firmly believes that apart from simple profit and sales analysis, a meticulous investor must assess Free Cash Flow and Return on Capital to gain deeper insights and avoid sophomoric conclusions.While he favors underappreciated and misunderstood equities, he also acknowledges that some growth stocks do deserve their premium valuation, and its an investor’s primary goal to delve deeper and uncover if the market’s current opinion is correct or not.

Analyst’s Disclosure: I/we have no stock, option or similar derivative position in any of the companies mentioned, and no plans to initiate any such positions within the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

Seeking Alpha’s Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

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NYT Strands Puzzle 810 Solved for May 22 2026 with Spangram ‘BACKPACKING’

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NYT Strands

NEW YORK — The New York Times Strands puzzle No. 810 for Friday, May 22, 2026, featured the theme “Hiking essentials,” with players finding outdoor and travel-related words including the spangram BACKPACKING.

The puzzle presented a letter grid where solvers identified connected words of four or more letters sharing a common theme. The spangram, which captures the puzzle’s core idea and often spans more of the board, was BACKPACKING.

The eight theme words were: COMPASS, HEADLAMP, TENT, TRAIL, HIKING, BOOTS, MAPS and WATER.

Strands, part of The New York Times Games lineup alongside Wordle and Connections, challenges players to uncover themed words in a jumbled grid. The game resets daily at midnight local time and provides hints through a “Sidekick” companion feature.

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The official theme hint released by The New York Times was “Hiking essentials.” An additional clue noted “Gear for the trail.”

Many players identified outdoor equipment quickly once spotting common items like BOOTS or TENT. The spangram BACKPACKING typically crossed horizontally or diagonally through the center of the grid.

Yesterday’s puzzle, No. 809 on May 21, carried the theme “In a material world” with the spangram FABRICS and words including COTTON, DENIM, FLEECE, LINEN, SATIN, SILK, VELVET and WOOL.

Strands requires finding between six and eight themed words plus the spangram. Players earn stars based on performance, with perfect solves earning the maximum. Non-theme words found along the way provide extra hints.

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Community reaction on platforms like Reddit’s r/NYTStrands described puzzle 810 as moderately challenging for those familiar with hiking culture, though some urban players noted less familiarity with certain trail-specific terms.

The New York Times publishes a daily Strands Sidekick article offering progressive hints, such as the first letters or directions of remaining words. For May 22, hints helped solvers distinguish between theme words and filler terms like PATH or GEAR.

Strands was developed as part of the expansion of NYT Games following the success of Wordle. It combines word search mechanics with thematic grouping, requiring both vocabulary knowledge and pattern recognition.

Players often begin by scanning for longer words or obvious clusters, such as common hiking gear. Strategies include noting vowel placements and eliminating letters used in already-found words.

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Puzzle 810 used a standard grid layout typical for Strands. The spangram BACKPACKING connected multiple trail-related terms thematically and visually across the board.

The game has grown in popularity since its introduction, attracting solvers who enjoy its mix of discovery and satisfaction upon completing the grid. Social media shares of solved grids with emoji indicators have become common.

For May 22, 2026, completing the puzzle yielded words directly tied to outdoor adventure and preparation. HEADLAMP and COMPASS represent essential navigation tools, while TENT and BOOTS denote core camping equipment.

Tomorrow’s puzzle, No. 811 for May 23, 2026, will introduce a fresh grid and theme at midnight. The New York Times advises attempting solves before checking solutions to preserve the experience.

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Strands maintains no repeats in its curated word selections. Editors balance accessibility with challenge, occasionally incorporating cultural or everyday references.

Educational applications include vocabulary building and categorical thinking. The puzzle’s web and app accessibility supports play on multiple devices with features like dark mode.

As of midday May 22, online discussions continued with players comparing solve times and sharing strategies for puzzle 810. Many reported completing it with few or no mistakes after identifying the hiking connection.

The New York Times Games team curates daily content to sustain engagement across its puzzle portfolio. Strands No. 810 exemplified a cohesive theme that rewarded general knowledge of outdoor activities.

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