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Who should I start for Week 2 Fantasy Football?

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The opening week of the 2026 NFL season is done and dusted, and fantasy football league managers are gearing up for Week 2. They’ll be looking to make roster moves that’ll either give them their second win of the campaign or get to .500.

Two Buffalo Bills wide receivers to watch in the upcoming week are D.J. Moore and Khalil Shakir. With that in mind, here’s which veteran wideout you should start in Week 2.

Should I start D.J. Moore or Khalil Shakir for Week 2 Fantasy Football?

In the offseason, the Buffalo Bills acquired D.J. Moore from the Chicago Bears in exchange for a 2026 second-round draft pick. The veteran wideout was fresh off his eighth year, amassing 50 receptions, 682 yards, and six touchdowns in 17 games catching passes from Caleb Williams.

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Moore was phenomenal in his Bills debut, catching five passes for 100 yards and one touchdown. His football IQ was key in him scoring a 43-yard TD against the Houston Texans.

Khalil Shakir has spent his entire professional football career with the Bills. He entered Year 5 as the team’s WR2 behind the newly acquired Moore.

Shakir had a solid but unspectacular start to the season. He posted a stat line of four receptions, 50 receiving yards and no touchdowns.

While D.J. Moore and Khalil Shakir are talented players in their own right, Moore seems the better Week 2 start. As Josh Allen’s primary target, Moore is the most likely source of fantasy points in the Bills receiver room.

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Moore is the clear WR1 and high-end option, while Shakir occupies a lower-ceiling supporting role. Furthermore, Moore’s ranking as a strong top-15/20 option makes him too tantalizing to ignore.

How to watch Buffalo Bills vs. Detroit Lions?

The Buffalo Bills continue their campaign against the Detroit Lions. Both teams will look to record their second win of the season.

With the game on Thursday, here’s what you need to know to watch it.

  • Date: Thursday, Sept. 17
  • Time: 8:15 p.m. ET
  • Venue: Highmark Stadium in Orchard Park, New York
  • Livestream: Amazon Prime Video