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T.H.E. Show Vegas 2026: Best in Show Winners and Honorable Mentions

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T.H.E. Show returned to the Alexis Park Hotel in Las Vegas from March 20 to 22, 2026, marking its 30th anniversary right where it started. As North America’s longest running hi-fi show, its survival is not luck. It is persistence. Credit goes to the late Richard Beers for building it, Maurice Jung for keeping it alive after 2016, and now Emiko Carlin, who is steering the brand into its next phase with expanded events in Austin and New York City. The show had moved from Las Vegas to Southern California with stops in Newport Beach, Irvine, Long Beach, and now Costa Mesa, but it is still standing. That alone says something in an industry that tends to burn through its own history.

Context matters, and 2026 is shaping up to be one of the busiest show calendars this industry has ever seen. Between eight CanJam events, AXPONA, CES, ISE, NAMM Show, CEDIA Expo, the relocated Vienna based HIGH END, and a growing list of shows in Toronto, Paris, Singapore, SWAF, and CAF, it is relentless. There is barely time to unpack before the next badge gets printed.

Which makes T.H.E. Show’s return to Las Vegas feel less like nostalgia and more like defiance. Thirty years in, it is still in the fight.

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With four events on the T.H.E. calendar in 2026, the Vegas stop did not exactly start on solid footing. The show was originally scheduled for January 9 to 11 at the Tuscany Suites & Casino, but had to be postponed to March due to unforeseen issues with the venue. Credit where it’s due, the team managed to regroup and secure the Alexis Park Hotel in less than three months. That kind of turnaround is not easy in Las Vegas, where convention space gets locked up fast.

There were tradeoffs. The new dates could not accommodate every exhibitor, and the show ended up noticeably smaller than originally planned. In total, eight oversized ballrooms were filled with high-end audio systems, supported by a modest marketplace that included T10 Bespoke, Island Routers, a vinyl seller, and a portable audio accessories vendor. It felt more curated by necessity than design.

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Timing did not help either. Running the same weekend as the Montreal Audiofest split both exhibitors and attendees across two countries that are not exactly a quick plane ride apart. Add AXPONA 2026 looming just weeks later, with the eCoustics team heading to Chicago that same week, and the reality sets in. There is only so much travel budget and bandwidth to go around, even in an industry that seems determined to test both in 2026.

Best in Show


Best Over $50K: YG Acoustics / Bergmann

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I’ve heard a number of YG Acoustics systems at shows over the years, and they rarely miss. This time, instead of rolling in with something that costs as much as a brownstone, they kept it almost reasonable. Almost. The Vegas system (presented by Supreme Acoustic Systems) came in around $100K and centered on the Vantage 3 Live active towers at $73K per pair, paired with a Bergmann Magne Airbearing Turntable at $12K, all sitting on a Music Tools ISOstatic rack at $1,495 per level.

The setup was refreshingly clean. No spaghetti pile of cables, no rack full of separates. Just two power cords and a pair of optical cables, one feeding each speaker. That alone tells you this is not your typical active speaker. The Vantage 3 Live uses a fully integrated DSP architecture with an external control unit that handles preamp duties and includes a phono stage. Everything is managed upstream, then sent digitally to the speakers.

The key here is that the signal stays in the digital domain all the way to the speakers, or is converted to digital before it gets there. That is why YG uses optical connections instead of traditional speaker cables. It is a different way of thinking about system design, and it cuts out a lot of variables.

There is no Bluetooth or Wi-Fi, but Ethernet based network streaming is built in, with support for TIDAL Connect and Qobuz Connect, and optional Roon integration. Use your phone or tablet, hit play, and let the system do the rest. No clutter, no guesswork, and very little standing between you and the music.

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Bergmann Magne Airbearing Turntable at T.H.E. Vegas 2026
Bergmann Magne Airbearing Turntable with YG Acoustics Vantage 3 Live preamp/control unit.

Additional elements rounded out the system, including AGS Diffusors (Acoustic Groove System) from Nihon Onkyo Engineering, which could easily add another $20K to the total. No, I didn’t A/B test them like a lab experiment, but patterns matter. Two of the best sounding rooms at the show used AGS, and that’s not a coincidence. In addition, power conditioning was handled by the AudioQuest Niagara 5000 at $6,900, delivering clean and stable current to the entire system.

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The Vantage 3 Live is not shy about muscle. Each speaker packs 2,100 watts of amplification, with 700 watts dedicated to each driver. That kind of headroom is not just for bragging rights. It shows up immediately in control, dynamics, and composure, regardless of source.

“Is This Love” by Bob Marley and the Wailers on vinyl was captivating. The soundstage stretched wide without losing focus, and Marley’s voice stayed locked dead center. It had the kind of precision you expect from a mastering studio, pulling every last bit of information out of the grooves without sounding clinical.

Switching to digital via Roon and Anette Askvik’s “Liberty” didn’t feel like a compromise. Nothing collapsed, nothing softened. The presentation remained spacious, detailed, and controlled, with a level of consistency between analog and digital that most systems struggle to achieve. This is what YG does when everything lines up.

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Learn more at supremeacousticsystems.com or listen to sound clips on Instagram.

Best Under $50K: Atlantis Lab / Neoson / Audiobyte

atlantis-lab-a31-pro-loudspeakers-vegas-2026
Atlantis Lab A31 Pro Loudspeakers in foreground.

Interestingly, just a few rooms over, the Atlantis Lab speaker system (presented by U.S. distributor Decibel+) went in the exact opposite direction of the YG setup. Where YG leaned on brute force and digital control, this one stripped things down to something far more old school. We’re talking roughly 1/100th the power, less than half the price, and yet it delivered a wildly intoxicating tube driven presentation that pulled you in just as quickly, if not faster.

The system was built around three brands that, frankly, were not on my radar before this show. Atlantis Lab handled loudspeakers, Neoson provided amplification, and Audiobyte (new company out of Romania) rounded things out with a streamer and DAC.

It should not have worked as well as it did on paper, especially in a show environment. But sometimes the rooms that make the least sense end up being the ones you remember. This was one of them.

neoson-evolution-veags-2026
Neoson Evolution Tube Amplifier

Atlantis Lab brought its high efficiency loudspeaker lineup, with models ranging from just over $3K to roughly $24K. The system was driven by the Neoson Evolution Tube Amplifier at $11,828, delivering 20 watts per channel of pure Class A power. Digital duties were handled by Audiobyte with the SuperHub streamer ($4K) and SuperVOX multibit DSD DAC ($4,500).

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What made this setup more than just another good room was the backstory. We were told that each of the French brands was founded by two friends who intentionally designed their products with the other in mind. That kind of collaboration usually sounds like marketing copy. Here, it translated into real system synergy.

Atlantis Lab Loudspeakers T.H.E. Vegas 2026
Background (left to right):
Atlantis Lab A16 Pro ($3,218)
Atlantis Lab A18 Pro ($4,960)
Atlantis Lab A21 Pro ($4,196)
Atlantis Lab A23 Pro ($6,466)
Atlantis Lab A31 Pro ($14,194)
Foreground:
Atlantis Lab A38 Pro ($23,939)

I spent time with the three largest Atlantis Lab floorstanding models, all paired with the same Neoson Evolution Tube Amplifier and Audiobyte front end. The A23 Pro ($6,466 per pair) did not quite deliver the same level of impact, but that felt more like a room mismatch than a flaw. Large hotel ballrooms are not forgiving, and if you are not sitting in the right spot, even good speakers can sound a bit restrained.

The two larger models stepped up in a meaningful way. They filled the room with more depth, width, and texture, the kind of presentation you usually do not hear until prices climb into far more uncomfortable territory. Comparing the A31 Pro and A38 Pro, which are separated by roughly $10K, was less straightforward. The flagship may have offered a bit more bass weight and scale, but the difference was not night and day. Some of that could have been expectation bias creeping in.

What stood out with both was their ability to throw a wide, stable soundstage while maintaining composure off axis. They did not collapse the moment you shifted in your seat. More importantly, they had a knack for uncovering layers of detail without sounding analytical, pulling you deeper into the performance rather than pushing it at you.

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These are not brands most people walk into a show expecting to hear. That should change. 

Learn more at Decibel+ or hear sound clips on Instagram.

Honorable Mentions


Oriaco G6 / Electocompanient

oriaco-g6-vegas-2026

Tony Minasian’s custom built loudspeakers remain one of those under the radar discoveries you tend to only encounter at T.H.E. Show. He is not chasing mass market appeal. He builds each pair by hand using the best parts he can source, and prices them accordingly. At $4,500 per pair, his bookshelf models are not entry level, but they are clearly aimed at listeners who care more about nuance than brute force, especially those drawn to acoustic, unamplified music.

The Oriaco G6 is the standout. It has an uncanny ability to expose the small things that most speakers gloss over. The pluck of a guitar string, the decay of a piano note, the snap of a snare drum. Nothing feels exaggerated, just revealed with a level of clarity that pulls you in rather than pushing detail at you.

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Tony usually keeps things grounded with a Denon integrated amp and a vintage Marantz CD player, but this year he stepped it up with Electrocompaniet electronics. The system included the ECI 6 MKII integrated amplifier ($6,500) and EMC 1 MKV CD player ($7,200), bringing the total system north of $20K. He even supplied a full loom of his own hand crafted cables, adding another $2,300 to the tally.

It is a complete system with very little left to chance, but the real story is the speaker which features an extra up-firing tweeter for spaciousness. If you are in the market for a high-end bookshelf and live anywhere near Southern California, it is worth reaching out for an audition. Or wait for T.H.E. Show SoCal, where there is a good chance you will find Tony set up again, quietly reminding people what a well voiced speaker can do.

Learn more at tonianlabs.com or hear sound clips on Instagram.

KEF R3 Meta / Eversolo

kef-eversolo-angle-vegas-2026

Stepping down to something far more attainable, Desert Premium Audio demonstrated a KEF and Eversolo system that landed just north of $16K and made a strong case for smart system building over brute force spending.

At the core were the R3 Meta bookshelf speakers ($2,500 per pair), supported by dual KEF KC92 subwoofers ($2,500 each), creating a full range foundation that punched well beyond what most would expect from standmounts. Amplification came from the Eversolo AMP-F10 ($2,480), while the DMP-A10 ($4,000) handled preamp duties and streaming. Rounding things out, the Onix XST20 SACD/CD transport ($2,399) added a physical media option for those not ready to abandon discs entirely.

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It is a thoughtfully assembled system that balances modern streaming convenience with old school sources, and more importantly, shows how far careful matching can take you without chasing six figure territory.

German Physiks

german-physiks-vegas-2026

The most expensive system at T.H.E. Vegas came courtesy of Aaudio Imports, and it did not hold back. Priced just shy of $400K, the setup centered on the distinctive Borderland MK II omnidirectional loudspeakers from German Physiks ($54K per pair), driven by the Emperor Extreme solid state integrated amplifier ($60K). Cabling alone, from Stage III, accounted for well over $100K, which tells you exactly where this system was aimed.

The source chain was equally ambitious. A Pink Faun 2.16 Ultra music server and streamer ($43K) fed the system alongside the Ancient Audio Lector Joy CD player ($26K). Digital conversion was handled by the Ypsilon DAC 1000 SE ($50K), supported by a SIN PSD 10 power distributor ($25K), Reiki network switches ($10K), and ART electromagnetic treatment ($18K) to address every possible variable in the signal chain.

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On paper, it is the kind of system that should stop you in your tracks. In practice, I wanted to be convinced. Here’s a sound clip on Instagram.

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T10 Bespoke

t10-bespoke-carbon-phantom-vegas-2026

Bear Clark, better known as “Hi-Fi Bear,” was on hand showing the T10 Bespoke wireless earbuds that we named Best in Show at CES 2026 just a few months ago. Starting at $3,000, each pair is hand built and fully customizable, along with its matching pendant charging case. And when we say customizable, we mean it. Snakeskin, gemstones, even diamonds. If you can imagine it, he can probably make it.

Or you can skip the subtlety entirely and go straight for The BillionEAR Attaché Smoker’s Edition at $14,500, which bundles the earbuds in an attaché case with cigars, a smoking pipe, and a few other indulgences thrown in for good measure.

Learn more at t10bespoke.com.

Usher Grand Tower

usher-grand-tower-loudspeakers-vegas-2026

The largest loudspeakers at T.H.E. Vegas came from Usher Audio with the Grand Tower ($42,000 per pair), driven by the BMC Audio CS3 integrated amplifier (around $10K). On paper, 200 watts per channel should have been more than enough to get them moving.

In reality, the room won. Inside a massive untreated ballroom, the Grand Towers struggled to pressurize the space and never quite locked in. It was less about the speakers and more about the environment. Even big systems can feel small when the room refuses to cooperate.

Island Router

island-router-vegas-2026

The Island Router is aimed at listeners who take their network as seriously as their system. Priced at $499, it brings enterprise grade routing and firewall capability into the home, with features like fault tolerant failover when two internet lines are connected, straightforward app based setup, and optimization designed to squeeze the most out of whatever bandwidth your ISP delivers.

There is a catch. No built in Wi-Fi. You will need to connect a separate wireless access point or hotspot if you want coverage throughout the house. It is not designed to be an all-in-one solution. It is designed to be stable, secure, and out of the way.

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Ai Pro

Ai Pro offered up a range of affordable fashion headphones, charging cases, and solar charger.

T.H.E. Vintage Lounge

vintage-lounge-vegas-2026

A solid selection of vintage gear was also in active rotation, not just sitting there for nostalgia points. Highlights included the original Klipsch Cornwall, JBL 4430, and Falcon Acoustics LS3/5a, alongside racks of classic amplification. 

The Bottom Line

T.H.E. Vegas 2026 was not the biggest show, and it never really recovered from the last minute venue change or the unfortunate calendar clash with the Montreal Audiofest. The lighter exhibitor list and smaller footprint were noticeable. There is no point pretending otherwise.

But smaller is not always worse. The upside was real. Less crowd noise, more time in the rooms, and actual conversations with designers and distributors that did not feel rushed or transactional. It created space to hear systems more clearly, swap components, and discover brands that might have been lost in a larger, more chaotic show.

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Credit to the T.H.E. team for getting this event back on its feet under difficult circumstances. That kind of recovery is not easy, especially in a year where the industry calendar is already stretched thin.

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Next up, T.H.E. heads to Austin from May 22 to 24, 2026, while AXPONA 2026 is right around the corner. We will be in Chicago next week, where the scale, competition, and expectations all ramp up.

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Sony’s PS5 Price Hikes Prove This Console Generation Is Far From Over. Good.

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If you’ve been holding off on picking up a PlayStation 5 in hopes of a price cut, bad news: the cost of every model of Sony’s all-conquering console has instead just gone up considerably.

It’s a move that breaks with decades of tradition (or at least consumer expectations) and is undoubtedly a blow for anyone hoping for a discount, five years into the current console generation. However, it’s also a sign that the current generation is likely to stick around for a while yet—and that may be a good thing, for the industry and players alike.

Historically, at this point in a console generation, incumbent hardware sees steep discounts. For example, the PS4, which launched for $400 in 2013, was retailing for $300 by 2018, a 25 percent decrease. Even if hardware is loss-leading, it’s a pricing trajectory that’s usually win-win for manufacturers and customers alike. Production and component costs will typically have dropped over that half-decade, allowing companies to drop the retail price, often alongside slimmed-down hardware revisions. At the same time, players who weren’t won over at a console’s launch have a cheaper entry point and years of games to catch up on. But this generation has been anything but typical.

Generational Abnormalities

The AI bubble has seen RAM and SSD storage prices skyrocket in the last few months, impacting the entire global tech sector. Sony as a whole has been hit hard by this, with the recent announcement that it was suspending its memory card business, while the PlayStation corner of the fiefdom just confirmed long-standing rumors of price increases for its console family.

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The new MSRPs went into effect on April 2, and there’s no sugarcoating that they mark significant increases. The “entry-level” digital edition PS5 console—the one without a disc drive—is the worst hit, leaping to $600. That’s $100 higher than its previous US retail price (which was already up following an earlier hike back in August 2025, driven by Trump’s tariffs) and a staggering 50 percent higher than its $400 launch price back in 2020.

The base PS5 with a disc drive is up 30 percent on its original $500 price, now costing $650, while the PS5 Pro “only” goes up around 29 percent from its $700 launch price, setting buyers back $900—though it also doesn’t come with a disc drive, so prepare to shell out another $80 to play physical games or Blu-ray movies. Elsewhere, the PlayStation Portal, Sony’s handheld that allows users to stream games from their PS5 or the cloud, has also increased by $50, from $200 to $250.

PlayStation is far from alone in increasing its prices. Xbox increased its hardware and GamePass subscription costs multiple times in 2025, eventually bringing the MSRP of the top-end 2-TB Xbox Series X to its current $800, and is rumored to be considering another hike. The Switch 2 dodged tariff-induced price hikes at launch but is also reportedly “contemplating raising the price of that device in 2026,” per Bloomberg—and the same report suggests Sony may be delaying the inevitable PlayStation 6 to as far off as 2029, all due to the AI-induced parts crisis.

Even Valve’s handheld Steam Deck isn’t immune—while prices have so far only risen in Japan, South Korea, and Taiwan, the manufacturer has announced that the original 256 GB, LCD-screen model (the cheapest) “is no longer in production, and once sold out will no longer be available” while the newer OLED models, available with either 512 GB or 1 TB of storage “may be out-of-stock intermittently in some regions due to memory and storage shortages.”

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Will ‘AI-Assisted’ Journalists Bring Errors and Retractions?

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Meet the “journalist” who “uploads press releases or analyst notes into AI tools and prompts them to spit out articles that he can edit and publish quickly,” according to the Wall Street Journal.

“AI-assisted stories accounted for nearly 20% of Fortune‘s web traffic in the second half of 2025.” And most were written by 42-year-old Nick Lichtenberg, who has now written over 600 AI-assisted stories, producing “more stories in six months than any of his colleagues at Fortune delivered in a year.”

One Wednesday in February, he cranked out seven. “I’m a bit of a freak,” Lichtenberg said… A story by Lichtenberg sometimes starts with a prompt entered into Perplexity or Google’s NotebookLM, asking it to write something based on a headline he comes up with. He moves the AI tools’ initial drafts into a content-management system and edits the stories before publishing them for Fortune’s readers… A piece from earlier that morning about Josh D’Amaro being named Disney CEO took 10 minutes to get online, he said…

Like other journalists, Lichtenberg vets his stories. He refers back to the original documents to confirm the information he’s reporting is correct. He reaches out to companies for comment. But he admits his process isn’t as thorough as that of magazine fact-checkers.

While Lichtenberg started out saying his stories were co-authored with “Fortune Intelligence”, he now typically signs his own name, according to the article, “because he feels the work is mostly his own.” (Though his stories “sometimes” disclose generative AI was used as a research tool…) The article asks with he could be “a bellwether for where much of the media business is headed…”

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“Much of the content people now consume online is generated by artificial intelligence, with some 9% of newly published newspaper articles either partially or fully AI-generated, according to a 2025 study led by the University of Maryland. The number of AI-generated articles on the web surpassed human-written ones in late 2024, according to research and marketing agency Graphite.”

Some executives have made full-throated declarations about the threat posed by AI. New York Times publisher A.G. Sulzberger said AI “is almost certainly going to usher in an unprecedented torrent of crap,” referencing deepfakes as an example. The NewsGuild of New York, the union representing Fortune employees and journalists at other media outlets, said the people are what makes journalism so powerful. “You simply can’t replicate lived experiences, human judgment and expertise,” said president Susan DeCarava.

For Chris Quinn, the editor of local publications Cleveland.com and the Plain Dealer, AI tools have helped tame other torrents facing the industry. AI has allowed the outlets to cover counties in Ohio that otherwise might go ignored by scraping information from local websites and sending “tips” to reporters, he said. It has also edited stories and written first drafts so the newsrooms’ journalists can focus on the calls, research and reporting needed for their stories…. Newsrooms from the New York Times to The Wall Street Journal are deploying AI in various ways to help reporters and editors work more efficiently….

Not all newsrooms disclose their use of AI, and in some cases have rolled out new tools that resulted in errors or PR gaffes. An October study from the European Broadcasting Union and the BBC, which relied on professional journalists to evaluate the news integrity of more than 3,000 AI responses, found that almost half of all AI responses had at least one significant issue.
Last week the New York Times even issued a correction when a freelance book reviewer using an AI tool unknowingly included “language and details similar to those in a review of the same book published in The Guardian.” But it was actually “the second time in a few days that the Times was called out for potential AI plagiarism,” according to the American journalist writing The Handbasket newsletter.
We must stem the idea being pushed by tech companies and their billionaire funders who’ve sunk too much into their products to admit defeat that the infiltration of AI into journalism is inevitable; because from my perch as an independent journalist, it simply is not…

Some AI-loving journalists appear to believe that if they’re clear enough with the AI program they’re using, it will truly understand what they’re seeking and not just do what it’s made to do: steal shit… If you want to work with machines, get a job that requires it. There are a whole lot more of those than there are writing jobs, so free up space for people who actually want to do the work. You’re not doing the world a favor by gifting it your human/AI hybrid. Journalism will not miss you if you leave…

But meanwhile, USA Today recently tried hiring for a new position: AI-Assisted reporter. (The lucky reporter will “support the launch and scaling of AI-assisted local journalism in a major U.S. metro,” working with tools including Copilot and Perplexity, pioneering possible future expansions and “AI-enabled newsroom operations that support and augment human-led journalism.”) And Google is already sponsoring a “publishing innovation award“…

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A new OnlyOffice fork is Europe's answer to Microsoft Office

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Developed by a consortium including Nextcloud, Ionos, and Proton, Euro-Office builds directly on the open-source OnlyOffice codebase. It offers a word processor, spreadsheet editor, presentation tool, and PDF editor, all supporting Microsoft formats (docx, pptx, xlsx) and open standards such as ODF. Its preview version is already available on GitHub,…
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Sunday Reboot: Gift bags, China flubs, and iPhones in space

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In this week’s “Sunday Reboot,” Apple’s gift bags and artifacts get a close look, China briefly gets Apple Intelligence ahead of schedule, and iPhones go to the Moon.

Orange smartphone with triple rear cameras appears behind a large view of Earth from space, showing swirling clouds over blue oceans against a dark starry background
The iPhone 17 Pro Max is in space.

Sunday Reboot is a weekly column covering some of the lighter stories within the Apple reality distortion field from the past seven days. All to get the next week underway with a good first step.
This week, Apple Ireland was fined by UK regulators for seemingly breaking sanctions on Russia, an AI porn startup sued Apple over its App Store rules, and the Apple Fitness+ chief prepares to retire amid claims he introduced a toxic mental health work environment.
Continue Reading on AppleInsider | Discuss on our Forums

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The deep-tech founder using AI to address immunology challenges

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Camille Bouget discusses how artificial intelligence is impacting innovation in the treatment of diseases affecting the immune system.

“Immuno-inflammatory diseases are often described as niche. They are not,” Camille Bouget, the CEO and co-founder of healthcare start-up Scienta Lab, explained to SiliconRepublic.com.  

With as many as one out of every 10 people in Western countries potentially impacted by an immuno-inflammatory condition, she noted, symptoms are often debilitating and the available therapeutic options frequently deeply inadequate for a significant proportion of patients. 

This is why, in 2021, Bouget co-founded Scienta Lab, a biotechnology company that aims to advance research within immunology via modern technologies such as artificial intelligence and EVA, the organisation’s multimodal AI model purpose-built for translational research in immunology and inflammation. 

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“It was designed to answer the concrete questions that R&D teams face throughout drug development: which therapeutic targets are worth pursuing, which preclinical biological signals are robust enough to carry forward into clinical trials, and which patients are most likely to respond to a given candidate drug,” said Bouget. 

Applied across multiple stages of the pipeline, she explained, early on EVA can estimate therapeutic efficacy prior to a patient beginning treatment. As the programme advances, EVA can evaluate whether molecular signals observed in animal subjects are likely to translate to humans. And at the clinical stage, it can support the identification of patient subgroups for more precisely designed trials.

“The primary beneficiaries are biopharmaceutical and biotech companies working in immunology and inflammation,” she said.

“Ultimately, however, the downstream beneficiary is the patient: better-designed trials, fewer failed programmes and faster access to treatments that genuinely address unmet needs in diseases like rheumatoid arthritis, lupus and inflammatory bowel disease.”

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Why AI?

A persistent challenge for Bouget and the industry she operates within has been in properly communicating the complexity of what they do in a manner that is accessible for all of the major stakeholders, be they investors, partners or the broader public.

“Immune diseases are notoriously difficult to characterise”, she noted, as often even the experts don’t always know how to measure them, what might prompt a flare-up, or why a treatment is effective for one patient but fails to work for another. 

“Convincing people that AI can meaningfully navigate that complexity without overpromising requires constant effort,” she said, especially as a young deep-tech company in an industry that is currently dominated by what she referred to as larger key players. 

She is of the opinion that the implication of AI for patients is significant, not least because the immunology drug development pipeline has historically suffered from high late-stage attrition, with programmes failing at phase II or phase III after years of investment and work. 

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“Each of those failures represents not only a financial cost, but delayed or denied access to potentially effective therapies,” said Bouget. 

“AI that genuinely improves the translational accuracy of preclinical decision-making can meaningfully shorten that timeline and shift more resources toward candidates that are more likely to succeed.”

Sturdy foundations

But it isn’t simply a matter of having access to advanced technologies. For Bouget, multidisciplinary teams of scientists and engineers are critical to the overall success of any organisation attempting to transform immunology research and development.  

She said: “Multidisciplinary teams are the entire foundation of doing this well. The failure mode we see most often in the application of AI to drug development is a disconnect between the computational sophistication of a model and its biological relevance. 

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“A model trained without deep immunological understanding may optimise for the wrong signal. Conversely, a team with outstanding biological expertise but limited machine learning capability will struggle to extract meaningful structure from the scale of data that modern multiomics generates.”

At Scienta Lab, the co-founding team consists of a pharmacist and former industry strategist, a biomedical engineer, and a mathematician with deep AI expertise.

“Day-to-day, our team spans immunology, bioinformatics, machine learning and clinical pharmacology,” Bouget explained.

“The ability to build bridges between those disciplines, to have a conversation where a wet-lab immunologist and a transformer architect are genuinely learning from each other, is what allows us to build models that are both technically rigorous and biologically meaningful.”

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She added: “Organisations that try to solve this problem with either pure data science or pure biology will hit a ceiling. The translational gap in drug development is not fundamentally a data problem or a computing problem alone, but one of understanding that requires genuinely integrated teams.”

Don’t miss out on the knowledge you need to succeed. Sign up for the Daily Brief, Silicon Republic’s digest of need-to-know sci-tech news.

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Crooks Behind $27M in ‘Refund’ Scams Busted By YouTube Pranksters After Being Lured to Fake Funeral

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One crime ring scammed 2,000 elderly people of more than $27 million between 2021 and 2023 using tech support/bank impersonation/refund scams. “Victims were in their 70s and 80s,” reports the U.S. Attorney’s office for California’s southern district. Victims were first told they’d received a refund (either online or via phone), but then told they’d been “over-refunded” a massive amount, and asked to return that amount.

But 42-year-old Jiandong Chen just admitted Thursday in a U.S. federal court that he was involved in the fraud and money laundering via cryptocurrency — pleading guilty to two charges with maximum penalties of 40 years in prison and a $1 million fine, plus 20 years in prison with a maximum fine of $500,000 or twice the amount laundered. “Chen, a Chinese national, is the second defendant charged in a five-defendant indictment.” And what tripped him up seems to be that “Certain members of the conspiracy also did in-person pickups of money directly from victims…”

And so YouTube enters the story — when the scammers called pranksters with 1,790,000 subscribers to their “Trilogy Media” channel. In an elaborate three-hour video, the team of pranksters lured the scammer to a rented Airbnb where they’re staging a fake funeral with a nun. (One of the men acting in the video remembers “we start doing a prayer… I’m holding the scammer’s hand in my nun outfit…”)

They convince the scammer to collect the cash from a dead man — “Is there anything you’d like to say to him?” Then there’s demon voices. The scammer’s victim resurrects from the dead. Did the cash mule bring holy water?

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The end result was a video titled “CONFRONTING SCAMMERS WITH A FAKE FUNERAL (EPIC REACTIONS)“. But two and a half years later, their “cash mule sting house” video has racked up over 1.3 million views, 22,000 likes, and 2,979 comments. (“This video is longer than Oppenheimer. Thanks for the laughs fellas.”)

And the scammer is facing 60 years in prison.

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Engineer Launches Genius AI Scheme To Track The Price Of His Favorite Beer

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A man in Ireland has figured out a way to find the cheapest pint of Guinness using just AI programs. Matt Cortland became frustrated when he paid nearly $9 for a pint at a pub in Dublin, and decided he had to figure out a way to track prices across the country. 

The first step was to find out the prices. To do that, Cortland created “Rachel” using the AI voice-generation platform ElevenLabs, then had her call every pub across Ireland — with a Northern Irish accent, of course. She ended up calling over 6,000 pubs, asking each one what their price was for a pint of Guinness. 

The second step was to sort the data. He used Claude to create a price index called “Guinndex,” which he can update himself, or bartenders can update whenever prices change. This offers Cortland — and anyone else craving a Guinness — up-to-date prices.

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The key was making AI feel authentic over the phone

While it all sounds pretty methodical, the most successful part of Cortland’s AI procedure was making Rachel feel human. Rachel was inspired by Rachel Duffy, the winner of the U.K. reality show “The Traitors” – but given a Northern Irish accent. Cortland reported that most pubs across Ireland couldn’t even tell Rachel was an AI over the phone, which likely yielded more results. 

A wide range of industries has started using AI to make phone calls. A study of car dealerships found that when AI handled customer service calls, it actually seemed more successful than average phone calls across the industry. Data from Regal found that humans actually appear to prefer talking to AI representatives more than human ones, staying on the phone longer and providing longer responses. Rachel’s phone calls with pubs appeared to reflect this, with bartenders happily telling her that she could even come in and get a pint for free. 

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It seemed like they didn’t even know she was AI — in reality, AI robots aren’t having as much success in that category. People have also reported not enjoying AI-led job interviews, likely already biased since they know it’s AI on the other end. Maybe let’s stick to the AI pint trackers.



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This Android phone can run Windows games locally, no PC required

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In a recent video, creator ETA Prime showcases Red Magic’s phone running multiple Windows games directly on Android. The device is powered by a Snapdragon 8 Elite Gen 5 SoC, paired with 24GB of LPDDR5T memory and 1TB of UFS 4.1 Pro storage.
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Samsung will discontinue its Messages app in July and replace it with Google’s

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Samsung is putting the final nail in the coffin for its own messaging app. The smartphone maker posted an “End of Service Announcement” on its website, revealing that the Samsung Messages app will no longer be available by July of this year. Samsung also recommended that anyone still using Samsung Messages switch over to Google Messages as the default messaging app.

For Samsung Messages users in the US, the switch to Google offers RCS messaging that lets you send high-quality media, join group chats and get real-time typing indicators no matter the smartphone’s OS. Galaxy smartphone owners may lose out on some of the Samsung Messages customization options, but Google Messages will make up for it generative AI from Gemini that can remix your photos in chats. On top of those features, Google Messages makes it easier for Samsung users to switch chats between a smartphone, tablet or smartwatch.

It’s no surprise that Samsung is only using Google Messages from now on, since it has been phasing out Samsung Messages for a few years now. Dating back to the Galaxy Z Fold 6 and Flip 6, and then followed by the Galaxy S25 series, Samsung stopped preloading the Samsung Messages app and instead pre-installed the Google Messages app. The Samsung Messages app is still available on the Galaxy Store, but Samsung said the exact final date will eventually be announced on the app itself.

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Monzo quits the US to focus on Europe ahead of a London IPO

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In short: Monzo announced on 1 April 2026 that it is closing its US operations, stopping new American sign-ups immediately and shutting existing accounts by June, and cutting approximately 50 roles. The decision comes three months after the UK challenger bank received a full banking licence from the European Central Bank and the Central Bank of Ireland, opening up expansion across the EU. It also arrives as Monzo prepares for a London IPO that Morgan Stanley is advising on, with a target valuation of between £6 billion and £7 billion.

Monzo is leaving the United States. The UK challenger bank announced on 1 April 2026 that it would cease accepting new American customers immediately, cut approximately 50 US-based roles, and close all existing American accounts by June. In a statement, the company framed the decision as a deliberate reorientation rather than a retreat: “With a fast-growing customer base of 15 million in the UK and the growth opportunity our European banking licence creates, we’re making a deliberate, strategic decision to focus on scaling in our home market and Europe and to step away from the US.” The announcement ends a seven-year experiment that never fully resolved its central structural problem, Monzo could not get a banking licence in the US, and without one, it could not compete.

Seven years, no charter

Monzo announced its American expansion in June 2019, rolling out a simplified version of its app to US customers and partnering with Sutton Bank, an Ohio-based FDIC-insured institution, to hold customer deposits and issue debit cards. The arrangement was always a workaround: without its own banking charter, Monzo could not originate loans, access core payment infrastructure directly, or compete in the lending and interchange revenue streams that define US retail banking profitability. It filed an application with the Office of the Comptroller of the Currency for a national bank charter in April 2020, but withdrew the application in late 2021 after regulators signalled it would not be approved. The company faced opposition from the National Community Reinvestment Coalition, among others, which argued that Monzo had not demonstrated sufficient commitment to serving local community needs. After withdrawing the OCC application, Monzo continued operating in the US through partner institutions, but it never secured the infrastructure that would have made its American business structurally viable.

The result, after seven years, was a product that offered a digital current account but not the full-service banking relationship that Monzo had built in the UK. US customers could not access mortgages, personal loans, or the premium credit products that generate meaningful revenue. They had a sophisticated spending tracker and a card linked to a partner bank’s balance sheet. That is a reasonable travel companion. It is not a challenger bank.

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The European licence that changed the calculation

On 17 December 2025, the European Central Bank and the Central Bank of Ireland granted Monzo a full banking licence, making it the first digital bank to be fully regulated by the Central Bank of Ireland and establishing Dublin as its European headquarters. The licence unlocks what the OCC application never delivered: the right to hold customer deposits directly, originate loans, and operate as a full bank across the 27-member EU single market under the EU’s passporting regime. Europe’s appetite for homegrown technology champions in financial services has grown considerably in recent years, and Monzo’s Irish licence positions it to compete for that opportunity on equal terms with incumbent banks for the first time. The three months between the Dublin licence and the US exit announcement are not coincidental. The company now has a credible path to scaled profitability in a market where it is already the dominant challenger; the US, by contrast, remained a market where it was permanently constrained.

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An IPO in the background

The withdrawal also has a more immediate audience: the investors Monzo is courting ahead of a public listing. The company has appointed Morgan Stanley to advise on a London Stock Exchange IPO that is expected in 2026, with a target valuation of between £6 billion and £7 billion — compared with the $5.9 billion implied by a secondary share sale in October 2024. Companies preparing for public listings in 2026 have generally found that a clean, focused growth story commands a higher multiple than a sprawling international footprint with mixed results, and a US operation that could not clear its structural barriers was a complication the IPO story did not need.

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The listing has already generated internal turbulence. TS Anil, who served as Monzo’s CEO for five years, stepped down in February 2026 following a reported dispute with the board over the timing and location of the IPO. Anil is understood to have favoured an earlier listing and had expressed interest in a New York venue; the board opted for London and more time. Diana Layfield, who spent nearly a decade at Google and more than a decade at Standard Chartered, was named his successor in October 2025 and took the role subject to regulatory approvals. Her mandate is the European expansion and the public listing. The US exit is the first visible act of that mandate.

The numbers behind the decision

Monzo’s financial trajectory gives the pivot a logic that is easier to explain to prospective public market investors than to American customers receiving account-closure notices. For the financial year ending March 2025, the bank reported revenue of £1.24 billion, up 48% year on year. Adjusted pre-tax profit reached £113.9 million, an eightfold increase on the prior year. Customer deposits grew 48% to £16.6 billion. A year that saw digital banking’s growth trajectory sharpen considerably across European markets validated the core bet: that a mobile-first bank with no branch network could generate the kind of revenue and profit that commands a credible IPO valuation. The US, in that context, was consuming resources that could instead be deployed against a market where the regulatory framework and customer base are already in place.

The subscription and premium-tier model that has driven platform revenue growth across technology is central to how Monzo has reached profitability in the UK: Monzo Plus and Monzo Premium accounts charge monthly fees and bundle benefits including travel insurance, higher interest rates on savings, and cashback. Replicating that model in the US required a depth of product, overdrafts, credit, savings, that a partner-bank structure made impossible. In the UK and, increasingly, in Europe, Monzo can offer all of it.

The broader picture

The move leaves the US challenger banking market increasingly to domestic incumbents and to a handful of well-capitalised European fintechs that have managed to secure their own charters. Revolut, Monzo’s nearest European rival, has been pursuing a US banking licence since 2021 and has yet to obtain one. The structural barriers that defeated Monzo’s OCC application remain in place. The lesson emerging from several high-profile European technology companies is that the conviction to double down on home-market strength, rather than spreading capital across geographies where the terms are unfavourable, is increasingly what investors reward. Monzo’s board, in pushing for a London listing and a European expansion over an American one, appears to have reached the same conclusion.

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For American customers, the practical consequence is a June 2026 account closure. Monzo said it would provide guidance in the coming days on how to transfer funds, redirect direct deposits, and access statements after the accounts are closed. For Monzo itself, the US chapter closes with a banking licence in Dublin, a public listing in preparation, and 15 million customers in the UK who collectively generated more than a billion pounds in revenue in a single year. The experiment in America is over. The business case for ending it is not difficult to read.

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