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Enliven Therapeutics, Inc. (ELVN) Discusses Updated Phase 1 ENABLE Trial Data for ELVN-001 in Previously Treated Chronic Myeloid Leukemia – Slideshow (NASDAQ:ELVN) 2026-06-12

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

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Seeking Alpha’s transcripts team is responsible for the development of all of our transcript-related projects. We currently publish thousands of quarterly earnings calls per quarter on our site and are continuing to grow and expand our coverage. The purpose of this profile is to allow us to share with our readers new transcript-related developments. Thanks, SA Transcripts Team

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Facebook and MessengerDown? Facebook Experience Widespread Outages Affecting Users Globally

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X, Formerly Twitter, Offers Valuable Insights Into Self-Reported Chronic Pain Using Machine Learning: Study

NEW YORK — Facebook and its Messenger service suffered widespread disruptions on Friday, leaving millions of users unable to access the platforms and sparking frustration across social media as service monitoring sites reported elevated outage levels.

The issues, which began impacting users in various regions including the United States, Canada, South Africa, the Philippines and parts of Europe, affected both the main Facebook feed and Messenger functionality. Many reported sudden logouts, error messages when attempting to reload profiles, and inability to send or receive messages.

Downdetector and similar tracking platforms recorded sharp spikes in user reports, with complaints centered on login failures, feed loading problems and complete service unavailability. The timing coincided with peak usage hours in multiple time zones, amplifying the disruption for individuals relying on the platforms for communication, business and daily updates.

Scope of the Outage

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Users in multiple countries quickly took to X and other alternative platforms to report problems. Reports indicated issues with Instagram as well, suggesting broader Meta platform problems. One user in South Africa noted lack of access, while others in the Philippines and Canada confirmed similar experiences. In Italy and other European locations, users reported identical login and loading difficulties.

The outage appeared to affect both web and mobile app versions. Some users were unexpectedly logged out and encountered errors when trying to sign back in. Others saw blank feeds or persistent loading indicators. The problems were not universal but impacted a significant number of accounts worldwide.

Meta had not issued an official statement on the cause or expected resolution time as of midday Friday. The company’s service status pages showed no major alerts initially, creating a disconnect between official monitoring and real-world user experiences — a common occurrence during partial or rolling outages.

User Reactions and Workarounds

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Frustration was evident across social media. Many users expressed annoyance at the timing, particularly those using Messenger for personal and professional communication. Some speculated about potential causes, ranging from technical glitches to higher-than-normal traffic, though no confirmed explanation emerged.

Communities shifted to alternative platforms like X to coordinate and share updates. The account @status_is_down, which tracks service disruptions, actively monitored and responded to reports, confirming the issues and noting affected regions. Users from diverse locations, including Canada, the Philippines and Italy, provided real-time confirmations.

Downdetector itself faced related complaints in some areas, leading to humorous commentary about the scale of the disruption. One user quipped about needing to locate Xzibit in reference to the cascading failures.

Meta’s History with Outages

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Meta platforms have experienced notable outages in the past, sometimes lasting several hours and affecting billions of users globally. Previous incidents have been attributed to configuration errors, server overloads or backbone routing problems. The company typically resolves such issues through internal fixes and provides post-incident explanations.

Facebook and Messenger remain among the most widely used communication tools worldwide, with billions of monthly active users. Disruptions can have significant impacts on personal connections, small businesses and information flow, particularly in regions where alternatives are limited.

Broader Implications

The outage highlights the reliance many individuals and organizations have on Meta’s ecosystem. For businesses using Facebook for marketing and customer engagement, or families staying connected via Messenger, even temporary downtime creates inconvenience and potential lost opportunities.

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In an era of increasing digital dependence, such events raise questions about infrastructure resilience and the need for diversified communication channels. While Meta invests heavily in reliability, the global scale of its services makes complete prevention challenging.

Users are advised to check official Meta channels for updates and try basic troubleshooting steps such as restarting apps, clearing cache or switching networks. Patience is recommended as engineering teams work to restore full functionality.

Company Response Expectations

Meta has a track record of addressing outages promptly once identified. Past incidents have typically been resolved within hours, followed by transparency reports detailing root causes. Users can monitor @Meta or official help centers for any announcements.

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The incident serves as a reminder of the fragility of centralized platforms despite their scale and resources. As digital services become more integral to daily life, expectations for uptime and rapid recovery continue to rise.

What Users Can Do

Affected individuals should avoid repeated login attempts that might exacerbate server load. Using alternative networks or devices can sometimes bypass localized issues. For critical communications, having backup methods such as email or other messaging apps is advisable.

Businesses relying on Facebook should prepare contingency plans for similar disruptions. Diversifying presence across multiple platforms can mitigate risks associated with single-service dependence.

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Looking Ahead

As engineers address the underlying cause, normal service is expected to resume progressively. The event will likely be analyzed internally to prevent recurrence, potentially leading to infrastructure improvements.

In the meantime, users continue sharing experiences and seeking alternatives. The outage, while inconvenient, underscores both the reach of Meta’s platforms and the challenges of maintaining uninterrupted global service.

Friday’s disruption affected Facebook and Messenger users in multiple countries, highlighting the platforms’ central role in modern communication. As Meta works toward full restoration, the incident adds to ongoing discussions about digital infrastructure reliability and user dependence on major technology companies.

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The global scale of the problem serves as a notable reminder of how interconnected daily activities have become. Whether for personal connections or professional needs, the temporary unavailability of Facebook and Messenger impacted millions, prompting widespread calls for greater resilience in digital services.

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Thailand’s Princess Bajrakitiyabha Dies at 47 After Three Years in a Coma

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Essential Updates on Politics, Economy, Tourism, and Society

Thailand is in mourning following the passing of Princess Bajrakitiyabha Narendiradebyavati, the eldest daughter of King Maha Vajiralongkorn (Rama X), who died at the age of 47 after spending more than three years in a coma. The Royal Palace officially announced her death, confirming that she had been receiving medical treatment since collapsing in December 2021.

Background and Health Decline

Princess Bajrakitiyabha, widely known as “Princess Bha,” collapsed suddenly in December 2021 and never regained consciousness. She had been battling a prolonged infection that ultimately proved fatal. Despite extensive medical care over more than three years, her condition never improved sufficiently for recovery. Her death marks the end of a long and difficult period of uncertainty for the Thai royal family and the nation. | The Guardian


Royal Succession and Political Significance

As the second in line to the Thai throne, Princess Bajrakitiyabha’s death has significant implications for royal succession. She had long been considered the most prominent and capable potential successor, and many observers expected she could one day become Queen. Her passing leaves the royal palace without its most widely respected and anticipated successor, prompting renewed public and political discussion about the future of the Thai monarchy. The New York Times

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Legacy and Humanitarian Contributions

Champion of Legal Reform and Women’s Rights

Princess Bajrakitiyabha was internationally recognised for her dedication to legal reform and human rights, particularly her advocacy for the rights of women prisoners. She played a pivotal role in championing improved conditions for female inmates in Thailand and worked closely with the United Nations on justice reform initiatives. Her legal expertise and humanitarian work earned her widespread admiration both domestically and internationally.

Known as the “Lawyer Princess”

Often referred to as the “Lawyer Princess,” she held a doctorate in international law and was deeply involved in advancing Thailand’s legal and justice systems. Her contributions to disaster response, justice reform, and women’s rights have left a lasting impact on Thailand’s public policy landscape. World media widely covered her passing with tributes emphasising her intellectual legacy and commitment to justice.


Public Mourning and National Response

15 Days of National Mourning

The Thai government declared an official 15-day mourning period following her death. Crowds gathered across Thailand to pay their respects, with tears and tributes marking public spaces throughout the country. Thailand’s Prime Minister also issued a formal tribute, acknowledging her enormous contributions to Thai society and expressing the nation’s deep sense of loss. Euronews

Outpouring of Public Grief

The scale of public grief reflects the deep affection Thais held for Princess Bha. She was described by many as the “pride of Thailand,” a royal figure who combined her privileged position with genuine dedication to improving lives. Entertainment and sporting events were permitted to continue following her passing, though the nation remained in a period of solemn reflection.

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International Reaction

International media extensively covered her death, with tributes pouring in from around the world. She was acknowledged not only as a member of the Thai royal family but as a globally respected advocate for justice and human rights. Her work with the United Nations and her academic credentials gave her a standing that transcended her royal title, making her death a loss felt beyond Thailand’s borders. South China Morning Post


Looking Ahead

Princess Bajrakitiyabha’s death leaves Thailand at a significant crossroads regarding royal succession and the monarchy’s future direction. Her absence removes one of the most widely respected figures from the royal institution at a time when Thailand is navigating complex political and regional challenges. The nation now begins the formal mourning process while reflecting on the remarkable legacy of a princess who dedicated her life to law, justice, and humanitarian service.

Source : Google News – Search

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Texture, health central to Ingredion’s acquisition of Tate & Lyle

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Texture, health central to Ingredion’s acquisition of Tate & Lyle

Ingredion CEO says Tate & Lyle will shore up company’s healthful ingredients business.

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Exclusive | OpenAI Considers Drastic Price Cuts, Anticipating War for Users With Anthropic

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Exclusive | OpenAI Considers Drastic Price Cuts, Anticipating War for Users With Anthropic

OpenAI is considering drastically lowering the prices it charges users as it seeks to win customers from its rival Anthropic.

The company is weighing significant cuts to what it charges for tokens, the unit of measurement artificial-intelligence firms use to bill for their products, according to people familiar with the matter. The move would be in anticipation of similar cuts the company expects at Anthropic, the people said. 

Copyright ©2026 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7b1cdeb8

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Anonymous Tip Prompts Search for Nancy Guthrie Remains Near Mexico Border

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Nancy Guthrie

NOGALES, Mexico — An anonymous tip claiming Nancy Guthrie’s remains were buried in an unmarked grave near the U.S.-Mexico border prompted a search by a Mexican missing persons group, though the effort yielded no new evidence in the case of the 84-year-old mother of NBC “Today” show co-anchor Savannah Guthrie.

Ramona Guadalupe Ayala Ortiz, head of Buscando Corazones Nogales, said the group received the tip on Wednesday and conducted an initial investigation in the Mariposa area northwest of Nogales, Sonora. The location is known for previous discoveries of unmarked graves, with the group having located 25 such sites earlier this year. Despite extending the search deeper into the area, no signs of Guthrie were found.

“We received an anonymous call telling us that the woman’s [Guthrie’s] remains were in the Mariposa area — in a grave over a stream,” Ayala Ortiz told El Imparcial. The group plans to continue future operations in the region to search for Guthrie and other missing persons.

The search was conducted with support from the Sonora State Commission for the Search of Missing Persons, along with municipal and state officials providing security for volunteers. The tip represents one of the more specific leads in a case that has generated intense public interest but few concrete developments since Guthrie vanished from her Tucson home on Feb. 1.

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Ongoing Investigation in Arizona

Guthrie disappeared from her Catalina Foothills residence in the early morning hours. Security camera footage showed a masked individual attempting to disable a doorbell camera before her disappearance. Blood evidence was reportedly found at the scene, and she left behind critical heart medication. The case has been reclassified as a no-body homicide investigation by authorities, who continue to describe it as active.

Pima County Sheriff Chris Nanos and the FBI have received tens of thousands of tips, though no arrests have been made in direct connection with her abduction. A $1 million reward offered by the Guthrie family remains in place for information leading to her recovery or the identification of those responsible.

The proximity of the Mariposa search area to the border, roughly 70 miles south of Tucson, aligns with theories that the case may involve cross-border elements, though officials have not confirmed any such links. The desert terrain and history of unmarked graves in the region have complicated previous searches for missing persons.

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Expert and Family Perspectives

Former FBI agents and other analysts reviewing the case have suggested a high likelihood that the perpetrator or perpetrators had some connection to Guthrie. In a NewsNation special, a panel estimated a 92% chance the abductor knew her in some capacity, with possible involvement of more than one person. Such assessments are based on statistical patterns in similar cases involving elderly victims.

Savannah Guthrie has spoken publicly about the emotional toll on her family. She has described crying daily while balancing her professional responsibilities and supporting her children through the uncertainty. The family continues to cooperate fully with investigators while navigating intense media attention tied to her national platform.

Community and Social Media Impact

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The case has drawn significant attention from true crime enthusiasts and content creators, leading to increased activity near Guthrie’s neighborhood. Sheriff Nanos has criticized disruptive behavior by some social media streamers and issued enforcement actions against trespassing and public nuisance. A memorial near the home was removed, reportedly by the homeowners association.

The influx of amateur investigators has complicated official efforts while also generating additional tips. Authorities continue to urge the public to report information through verified channels rather than conducting independent searches that could interfere with the investigation.

Broader Context of Cross-Border Cases

Disappearances along the U.S.-Mexico border present unique challenges due to jurisdictional complexities, terrain and the volume of missing persons cases in the region. Groups like Buscando Corazones Nogales play a vital role in searching for remains and providing support to families on both sides of the border.

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The Mariposa area’s history of unmarked graves underscores the humanitarian issues in the region, where migrants and other vulnerable individuals have sometimes been interred without identification. While the latest search for Guthrie proved unsuccessful, it highlights ongoing efforts to resolve cold cases and provide closure to families.

Law Enforcement Coordination

U.S. and Mexican authorities maintain communication on cross-border cases, with the FBI and Pima County Sheriff’s Department leading the Guthrie investigation. International cooperation has been evident in recent enforcement actions against individuals interfering with the case, though no direct links to her disappearance have been publicly established.

A separate kidnapping case involving a Tucson woman near Guthrie’s neighborhood drew attention due to proximity, but police stated there is no evidence connecting the incidents. Investigators continue examining all potential leads, including digital records, neighborhood canvassing and forensic analysis.

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Path Forward in the Investigation

As the case enters its fifth month, authorities emphasize that it remains active with every resource being deployed. Technical evidence processing, tip evaluation and forensic work continue. The absence of remains has shifted focus to circumstantial evidence, digital trails and witness statements in building a potential case.

For the Guthrie family and the Tucson community, the prolonged uncertainty has been profoundly difficult. The latest search in Mexico, though unsuccessful, demonstrates that tips continue to be pursued thoroughly regardless of their origin.

Public cooperation remains crucial. Anyone with information is urged to contact the FBI at 1-800-CALL-FBI or the Pima County Sheriff’s Department. Even small details could help advance the investigation toward resolution.

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The Nancy Guthrie case has captured national attention due to her daughter’s prominence, keeping the search in the public eye and potentially generating new leads months later. As authorities pursue every avenue, the focus remains on bringing answers to the family and accountability for those responsible.

The latest development in Mexico adds another chapter to a complex investigation that spans jurisdictions and continues to evolve. While the search did not yield immediate results, it reinforces the commitment of both U.S. and Mexican groups to resolving missing persons cases along the border. The Guthrie family and investigators persist in their efforts, hoping for a breakthrough that provides closure after more than four months of uncertainty.

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Knicks Lead 3-1 as Spurs Host Game 5 with Wembanyama Seeking Series Revival

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Victor Wembanyama

SAN ANTONIO — The San Antonio Spurs will host a pivotal Game 5 of the 2026 NBA Finals on Saturday night facing elimination, with Victor Wembanyama and his teammates looking to extend the series against a surging New York Knicks team that holds a 3-1 lead.

The Knicks stunned the basketball world in Game 4 with a record 29-point comeback victory, taking a commanding advantage in the best-of-seven series. Now, the Spurs must win at home to avoid their season ending, relying on the towering presence of Wembanyama and home-court energy at Frost Bank Center.

Series Context and Knicks Momentum

New York seized control with an improbable rally in Game 4, overcoming a 29-point deficit to win 107-106 on OG Anunoby’s tip-in with 1.2 seconds remaining. Jalen Brunson led the way with 36 points, while Anunoby added 33. The victory moved the Knicks within one win of their first championship since 1973.

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The Spurs led by as many as 27 points in that contest but collapsed in the second half. Wembanyama expressed determination afterward. “I think it’s going to go one of two ways: a bad one and a good one. The bad one would be giving up. The good one would be getting stronger through this, getting more together,” he said. “I know this is what we’re going to do.”

Despite the setback, San Antonio has shown resilience throughout the postseason, overcoming multiple elimination games en route to the Finals. Home crowds have been electric, and the Spurs will look to harness that energy Saturday.

Wembanyama’s Role and Spurs Outlook

The 22-year-old Wembanyama has been a dominant force in his first Finals appearance, showcasing his unique blend of size, skill and shot-blocking ability. He will be central to any Spurs comeback, tasked with anchoring the defense while creating scoring opportunities on the other end.

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San Antonio’s supporting cast, including Keldon Johnson and De’Aaron Fox, has provided scoring bursts, but consistency has been an issue. Coach Gregg Popovich’s system emphasizes ball movement and defensive intensity, elements the Spurs will need to rediscover after Game 4’s late meltdown.

Playing at home gives the Spurs a significant boost. The franchise has a strong history of playoff comebacks, and fans will be eager to push the series back to New York for a potential Game 6.

Knicks’ Path to Victory

New York enters Game 5 riding high from its historic comeback. Brunson’s leadership and scoring, combined with Anunoby’s two-way impact and the supporting contributions from Mikal Bridges and others, have made the Knicks a formidable unit.

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Coach Mike Brown has emphasized defensive focus and avoiding complacency. “I don’t know if there was a play bigger than any other play in the history of Knicks basketball,” he said of Anunoby’s game-winner.

The Knicks’ ability to withstand early deficits and finish strong will be tested again on the road. Maintaining composure against a desperate Spurs team and limiting Wembanyama’s impact will be key priorities.

Key Matchups and Tactical Outlook

The battle between Wembanyama and New York’s frontcourt, particularly Mitchell Robinson and Precious Achiuwa, will be critical. Wembanyama’s length and versatility create matchup problems, but the Knicks have shown they can adjust defensively.

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On the perimeter, Brunson versus San Antonio’s guards will shape offensive flow. The Spurs need to disrupt Brunson’s rhythm while generating their own transition opportunities.

Three-point shooting and rebounding could swing the outcome. Both teams have capable shooters, but execution under pressure in a hostile environment will decide Game 5.

Historical and Broader Context

The 2026 Finals have delivered compelling basketball, highlighted by the Knicks’ Game 4 heroics. A Spurs victory Saturday would force a Game 6 in New York, extending what has been a competitive and entertaining series.

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For Wembanyama, a strong performance could further cement his status as one of the league’s brightest young stars. For the Knicks, closing out the series on the road would mark a significant achievement in their rebuild.

The NBA community has been captivated by the contrast in styles: New York’s gritty resilience versus San Antonio’s high-upside talent led by Wembanyama. Game 5 offers another chapter in this compelling narrative.

Fan and Media Anticipation

Expect a raucous atmosphere in San Antonio, with fans hoping to will their team to a victory that keeps championship dreams alive. National broadcasts will showcase the electric environment and the individual brilliance of stars on both sides.

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Analysts point to the Spurs’ home dominance and Wembanyama’s ability to elevate his game in critical moments as reasons for optimism. The Knicks, however, have demonstrated championship mettle with their Game 4 performance.

What to Watch in Game 5

  • Wembanyama’s scoring and defensive impact against New York’s interior.
  • Brunson’s ability to control the tempo and create for teammates on the road.
  • Second-half adjustments, as the Spurs faded in Game 4.
  • Three-point efficiency and offensive rebounding battles.

A Spurs win would set up a tense Game 6 in Madison Square Garden, while a Knicks victory would clinch the title in San Antonio, adding to the drama.

Conclusion and Series Outlook

Game 5 represents a must-win for the Spurs and a chance for the Knicks to seal their first championship in over five decades. Wembanyama’s leadership and the home crowd provide San Antonio with a fighting chance, but New York’s momentum and depth make them clear favorites.

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As the series reaches this critical juncture, both teams will leave everything on the court. The basketball world will be watching to see if Wembanyama can engineer a comeback or if the Knicks can finish the job on the road.

The 2026 NBA Finals have already produced memorable moments. Game 5 promises more intensity as the Spurs fight for survival and the Knicks pursue history. Saturday night in San Antonio will go a long way toward determining the champion.

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Wall St to open higher on Mideast deal hopes; SpaceX debut in focus

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Wall St to open higher on Mideast deal hopes; SpaceX debut in focus


Wall St to open higher on Mideast deal hopes; SpaceX debut in focus

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BlackRock BDEBT private credit fund repurchases hit 5% cap

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BlackRock BDEBT private credit fund repurchases hit 5% cap

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How Cracker Barrel’s CEO Saved Her Job by Abandoning Her Own Strategy

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How Cracker Barrel’s CEO Saved Her Job by Abandoning Her Own Strategy

Last summer, Chief Executive Julie Felss Masino was trolled mercilessly as she pressed forward with a Cracker Barrel CBRL 2.27%increase; up pointing triangle revamp, from remaking the folksy logo atop restaurants to pulling antique tchotchkes off the walls.

Amid the criticism, she was subjected to remarks about her eyeglasses and comments about her “woke” attitude. She fielded unsolicited business advice from President Trump over the logo redesign and company management. And activist investor Sardar Biglari vowed to remove her through a proxy battle.

Copyright ©2026 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7b1cdeb8

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Have you been mis-sold car finance?

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Have you been mis-sold car finance?

Martin Lewis has advice for those who have or who are planning to put in a car finance mis-selling claim.

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