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SL Science Holding Shares Surge 35% on Nasdaq Debut After SPAC Merger as Biotech Investor Interest Builds

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The Moderna vaccine can be stored at less extreme temperatures than the Pfizer/BioNTech jab

SL Science Holding Limited shares soared more than 34% to close at $5.99 Thursday following its recent listing on the Nasdaq Global Market through a business combination with a special purpose acquisition company, highlighting strong investor appetite for innovative cell therapy platforms in the competitive biotechnology sector.

The Taiwan-headquartered company, formerly known as SL BIO Ltd., completed its merger with Horizon Space Acquisition II Corp. and began trading under the ticker SLBT on June 15. The transaction valued the combined entity at approximately $5.6 billion, providing substantial capital to advance its pipeline of gamma delta T cell therapies targeting solid tumors.

SL Science focuses on developing off-the-shelf cellular and gene therapies, with particular emphasis on gamma delta T cells for treating challenging cancers such as pancreatic and brain tumors. The approach aims to overcome limitations of traditional autologous cell therapies, including scalability, cost and manufacturing consistency.

The company’s platform also includes research into armed T-cells and exosome-based products derived from plant and milk sources for regenerative medicine applications. These diversified efforts position SL Science at the intersection of immuno-oncology and regenerative therapies.

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SPAC Merger and Nasdaq Transition

The business combination with Horizon Space Acquisition II provided SL Science with access to public markets and additional funding through a PIPE investment. The listing marks a significant milestone for the preclinical-stage biotechnology firm seeking to accelerate clinical development.

Proceeds from the transaction will support research and development activities, manufacturing scale-up and potential strategic acquisitions. Management has outlined plans to advance lead candidates toward investigational new drug applications and early-stage clinical trials.

Biotechnology companies often pursue public listings via SPACs to expedite capital raising amid volatile traditional IPO markets. SL Science’s debut reflects continued investor interest in innovative cell and gene therapy platforms despite sector-wide challenges.

Pipeline and Scientific Approach

SL Science’s gamma delta T cell technology leverages a unique subset of immune cells with potential advantages in targeting solid tumors. Unlike conventional CAR-T therapies that have shown limited efficacy against solid cancers, gamma delta approaches may offer better tumor infiltration and reduced toxicity.

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The company is also exploring exosome therapies using milk-derived and plant-based sources for applications in skin care, wound healing and broader regenerative medicine. These products complement the oncology focus while generating potential near-term revenue through cosmetic and wellness channels.

Preclinical data has demonstrated promising results in various models, though clinical validation remains essential for regulatory approval and commercial success. The firm aims to establish standardized manufacturing processes to enable scalable production.

Market Context and Challenges

The cell therapy sector has experienced rapid growth but faces hurdles including high development costs, manufacturing complexities and reimbursement uncertainties. SL Science’s off-the-shelf approach seeks to address some of these challenges compared to personalized therapies.

Competition in immuno-oncology is intense, with major pharmaceutical companies and specialized biotech firms pursuing similar targets. Differentiation through proprietary technologies and combination approaches will be critical for market positioning.

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Regulatory pathways for cell and gene therapies have become more defined in major markets, though requirements for safety and efficacy data remain stringent. SL Science will need to navigate clinical trial requirements and manufacturing standards carefully.

Investor enthusiasm for biotechnology stocks fluctuates with broader market sentiment and clinical data readouts. SL Science’s post-listing volatility reflects typical patterns for newly public development-stage companies.

Financial Position and Strategy

As a preclinical company, SL Science currently generates limited revenue primarily from research services and early cosmetic products. The SPAC merger and associated financing provide runway for advancing its pipeline through key milestones.

Management has emphasized disciplined capital allocation focused on high-potential programs while exploring partnerships to accelerate development. Strategic acquisitions or licensing deals could expand the technology platform.

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The company’s leadership team includes executives with experience in biotechnology and public company operations. Recent appointments have strengthened capabilities in clinical development and regulatory affairs.

Long-term success will depend on clinical trial outcomes, regulatory approvals and commercialization strategies. The biotechnology sector rewards companies that deliver transformative therapies while managing development risks effectively.

SL Science’s Nasdaq listing provides visibility and access to capital markets that can support ambitious research programs. As the company progresses its pipeline, upcoming clinical data and regulatory interactions will be closely watched by investors and industry observers.

The debut performance underscores market appetite for novel cell therapy platforms amid growing interest in immuno-oncology and regenerative medicine. SL Science joins a cohort of companies aiming to address significant unmet medical needs through innovative approaches.

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Mexico stocks lower at close of trade; S&P/BMV IPC down 0.02%

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Mexico stocks lower at close of trade; S&P/BMV IPC down 0.02%

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German Drone Maker Quantum Systems Raises Funding at $8 Billion Valuation

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German Drone Maker Quantum Systems Raises Funding at $8 Billion Valuation

Quantum Systems said it had raised $1.2 billion at a valuation of roughly $8 billion, bringing in fresh capital to expand drone production and invest in software for autonomous systems powered by artificial intelligence.

The startup said European aircraft maker Airbus, asset manager Blackstone, private-equity firm Advent and equity investor Noteus Partners co-led the financing round, which also attracted interest from technology investment firm BOND, financial services firm Fidelity Investments, asset manager Wellington Management, investment firm A.P. Moller Holding, venture-capital firm Elephant Lake Ventures and existing shareholders like Balderton and HV Capital.

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Supreme Court’s Barrett fuels conservative wins while sometimes splitting with Trump

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Supreme Court’s Barrett fuels conservative wins while sometimes splitting with Trump


Supreme Court’s Barrett fuels conservative wins while sometimes splitting with Trump

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A Cable Scion’s Hardest Deal Yet: Comcast Co-CEO Brian Roberts’ Plan to Break Up His Family’s Company

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A Cable Scion’s Hardest Deal Yet: Comcast Co-CEO Brian Roberts’ Plan to Break Up His Family’s Company

Comcast CMCSA 0.25%increase; up pointing triangle co-Chief Executive Brian Roberts spent his 67th birthday finalizing a plan to split the cable and entertainment company his family built in two.

“Ralph would be excited,” one of his children texted him Sunday, referring to Ralph Roberts, the patriarch who co-founded and ran Comcast for nearly 40 years.

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Heat Waves Are Becoming a Chronic Drag on the Economy

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Heat Waves Are Becoming a Chronic Drag on the Economy
Ed Ballard

Heat waves are underscoring how global warming has become a here-and-now issue for economists. 

Temperatures are rising ahead of the July 4 weekend, with 100-degree highs—feeling hotter due to the humidity—forecast for various parts of the central and Eastern U.S. Areas home to more than 150 million people were covered by National Weather Service heat alerts as of midweek. 

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Heat wave disrupts Fourth of July events across eastern US

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Heat wave disrupts Fourth of July events across eastern US


Heat wave disrupts Fourth of July events across eastern US

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Death toll of Venezuela earthquakes rises to 2,645

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Death toll of Venezuela earthquakes rises to 2,645


Death toll of Venezuela earthquakes rises to 2,645

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Brazil stocks higher at close of trade; Bovespa up 0.74%

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Brazil stocks higher at close of trade; Bovespa up 0.74%

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Apple’s Foldable iPhone Surge Saves the S&P 500 From a Chip Rout as Weak Jobs Report Divides Wall Street

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iPhone 17e

NEW YORK — Apple’s stock surged nearly 5% Thursday, adding roughly $182 billion in market capitalization in a single session and single-handedly preventing what would have been a much sharper decline for the broader S&P 500, as a weak June jobs report, an ongoing chip sector pullback and lingering Middle East uncertainty sent most of the rest of the technology market lower heading into the Fourth of July holiday weekend.

The S&P 500 managed to finish essentially flat on the day, down just 0.2% by midday before recovering ground, while the Dow Jones Industrial Average climbed 0.7% and the Nasdaq Composite declined 0.8%. Eight of the 10 largest market capitalization moves in the S&P 500 on Thursday were negative, including sharp declines for Tesla and Micron Technology. Without Apple’s contribution, analysts noted, the broader index would have recorded a considerably more painful session.

The catalyst for Apple’s surge was a Bloomberg report indicating the company had instructed its parts suppliers to prepare for a large-scale rollout of foldable iPhones this fall, with the expected production target for 2026 now rising to approximately 10 million units, up from earlier forecasts of 7 to 8 million. That order volume increase signals Apple’s confidence that consumer demand for its first foldable smartphone will exceed initial projections. Alongside the foldable, Apple is reportedly preparing roughly 70 million iPhone 18 Pro and Pro Max units, setting up what the company expects to be one of the most commercially significant product launches in its recent history.

The foldable iPhone news came at an opportune moment for Apple investors who have been watching the stock navigate a difficult stretch defined by supply chain pressures, memory chip cost increases and publicly disclosed price hikes on its Mac and iPad lineups. The prospect of a new form factor capable of driving a significant upgrade cycle among the company’s existing customer base gave investors a concrete growth narrative to focus on heading into the back half of 2026.

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The rest of the day told a very different story for much of the technology sector. Tesla fell 7.4% even as the company reported June vehicle deliveries that came in 18% above analyst estimates, a counterintuitive reaction that market observers attributed almost entirely to profit-taking following a 13% price surge over the prior four trading sessions. Micron Technology, similarly near all-time highs after its extraordinary year-to-date run of more than 300%, declined 5.8%, weighed down in part by a price-fixing lawsuit related to older memory types that circulated through the financial news cycle during the session. Both moves contributed to the Nasdaq’s underperformance, though neither Tesla nor Micron is a component of the Dow, which helps explain the divergence between the blue-chip index’s gain and the tech-heavy Nasdaq’s decline.

The macro backdrop for Thursday’s session was defined by the June nonfarm payrolls report, which landed well below expectations. The Labor Department reported 57,000 new positions added in June, against economist forecasts of 110,000. May’s payroll numbers were revised downward as well. The unemployment rate edged lower to 4.2% from 4.3%, a technically positive reading but one that contradicts the weak hiring figure and reflects a falling labor force participation rate rather than broad employment strength. Treasury yields declined in response to the soft data, as bond market investors recalibrated expectations toward a Federal Reserve that would face reduced pressure to raise interest rates given the cooling labor market.

The geopolitical dimension of Thursday’s session involved the Strait of Hormuz, where the vessel backlog waiting to transit the critical waterway fell to 380 ships from 485 earlier in the week. However, only five ships actually passed through the strait in the preceding 24 hours, underscoring how far the shipping situation remains from normal despite diplomatic progress. U.S. and Iranian negotiators wrapped up the latest round of talks in Doha claiming what participants described as positive momentum, though no concrete breakthroughs have been announced. The next scheduled discussion will follow funeral proceedings for Iran’s late Supreme Leader, which are expected to conclude by July 9, a timeline that introduces additional uncertainty about when the substantive diplomatic work can resume.

Oil prices continued falling Thursday despite the limited physical improvement in Hormuz traffic, suggesting markets are pricing in future progress rather than current conditions. Gold and Bitcoin rallied simultaneously for the second consecutive session, a combination that some market participants described as unusual and potentially significant. The SPDR Gold Shares fund rose 2.1% while the iShares Bitcoin Trust ETF gained 2.6%. When investors move into both traditional and digital safe-haven assets at the same time, it typically signals a broad underlying uncertainty rather than a specific sectoral rotation.

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The broader week produced a pattern analysts have flagged as the dominant theme of 2026’s market: a clear rotation from high-flying technology and semiconductor growth names into steadier, more traditionally valued sectors including financials and industrials. The Dow outperforming the Nasdaq by 1.5 percentage points on Thursday alone illustrated that rotation in concentrated form. The chip sector’s two-day decline followed an 82% first-half gain across semiconductor stocks broadly, making some degree of consolidation not only expected but arguably overdue. The speed of the correction, however, has surprised even observers who anticipated a pullback after the sector’s extraordinary run.

With U.S. markets closed Friday for the Independence Day holiday, which falls on Saturday this year, investors have a long weekend to reassess their positions before trading resumes Monday. The Fourth of July closure also pushed the jobs report to Thursday rather than its usual Friday slot, making this week’s already compressed four-day schedule feel even more event-dense than typical pre-holiday periods.

Monday’s reopening will bring investors back to a market still processing a complicated set of signals: Apple’s foldable iPhone optimism colliding with a softening labor market, an ongoing diplomatic standoff in one of the world’s most important shipping lanes, a chip sector finding its footing after an extraordinary first half, and a Federal Reserve whose next move remains genuinely uncertain in a way that it has not been for much of the past several months. Whether Apple’s foldable iPhone story can maintain the momentum it generated Thursday, or whether the broader rotation out of technology names continues to dominate, will likely define the market’s first week of July trading when it resumes after the holiday break.

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Holiday Halt: NYSE, Nasdaq to remain closed today for Independence Day holiday

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Holiday Halt: NYSE, Nasdaq to remain closed today for Independence Day holiday
US financial markets will remain closed on Friday, July 3, in observance of the Independence Day holiday, as July 4 falls on a Saturday this year. Trading in equities and bonds will resume on Monday, July 6.

The closure applies to major US stock exchanges, including the New York Stock Exchange and Nasdaq, as well as the bond market. The bond market also ended trading early on Thursday, closing at 2 pm Eastern Time ahead of the long holiday weekend.

The holiday schedule follows the standard US market convention under which Independence Day is observed on the preceding Friday when July 4 falls on a Saturday. As a result, investors will have a three-day weekend before trading resumes with regular hours on Monday.

While stock and bond markets are shut, cryptocurrency markets continue to operate around the clock without interruption. Most commercial banks remain open on Friday, although some branches may operate with modified hours depending on the institution. Postal and delivery services largely maintain normal operations on Friday before adjusting schedules for the holiday on Saturday.

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The market closure comes after investors digested the June U.S. employment report, which influenced expectations for the Federal Reserve’s interest-rate path heading into the holiday weekend.


US financial markets will remain closed on Friday, July 3, in observance of the Independence Day holiday, as July 4 falls on a Saturday this year. Trading in equities and bonds will resume on Monday, July 6.
The closure applies to major US stock exchanges, including the New York Stock Exchange and Nasdaq, as well as the bond market. The bond market also ended trading early on Thursday, closing at 2 p.m. Eastern Time ahead of the long holiday weekend.The holiday schedule follows the standard US market convention under which Independence Day is observed on the preceding Friday when July 4 falls on a Saturday. As a result, investors will have a three-day weekend before trading resumes with regular hours on Monday.

While stock and bond markets are shut, cryptocurrency markets continue to operate around the clock without interruption. Most commercial banks remain open on Friday, although some branches may operate with modified hours depending on the institution. Postal and delivery services largely maintain normal operations on Friday before adjusting schedules for the holiday on Saturday.

The market closure comes after investors digested the June U.S. employment report, which influenced expectations for the Federal Reserve’s interest-rate path heading into the holiday weekend.

The shortened trading week was marked by heightened attention to economic data and monetary policy expectations. Investors assessed the latest labor market figures alongside signs of moderating inflation, with market participants recalibrating expectations for the timing and extent of future Federal Reserve interest-rate decisions. Trading volumes also tended to thin out ahead of the extended holiday weekend as many institutional investors wrapped up positions before the market closure.

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Looking ahead, investors will return to a calendar packed with corporate earnings announcements and fresh economic indicators that could shape sentiment in the second half of the year. Market participants will continue to monitor inflation trends, labor market conditions and comments from Federal Reserve officials for clues on the central bank’s policy trajectory, while developments in global trade and geopolitics are also expected to remain in focus.

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