Business
New Hampshire Man Survives Record 271 Days With Pig Kidney Before Human Transplant, Says He May Get ‘Decades’
BOSTON — A retired New Hampshire grocery store manager who once believed he was staring death in the face has become the longest-surviving recipient of a pig kidney transplant, living 271 days without dialysis before ultimately receiving a human kidney earlier this year, according to findings published Thursday in The Lancet medical journal.
Tim Andrews, 68, of Barrington, New Hampshire, first began discussing the experimental procedure with doctors in late 2024, when he was suffering from end-stage kidney failure and believed his time was running out.
“I didn’t think I was going to live through it, to be honest. But I wanted to do it for humanity,” Andrews told NBC News.
Andrews said the weight of his diagnosis prompted a moment of reflection that ultimately convinced him to pursue the experimental transplant, even without confidence he would survive it.
“I realized, OK, I’m a dead man. I’m a dead man walking,” Andrews said. “So I said to myself, ‘What have I done? What have I done with my life? This is an opportunity for me to do something that most people don’t get an opportunity to do, and that’s to help humanity.’”
Andrews said he was candid with Dr. Leonardo Riella, director of kidney transplantation at Massachusetts General Hospital and the study’s lead author, about his motivations heading into the procedure.
“This is about learning something. I don’t care if I die, as long as you learn one thing,” Andrews recalled telling Riella.
Andrews received the pig kidney transplant on Jan. 25, 2025, at age 66, through Mass General Brigham in Boston, making him part of an ongoing clinical trial examining the safety and viability of xenotransplantation, the transplantation of living organs between different species. Over the following 271 days, Andrews required no dialysis before ultimately receiving a human kidney transplant, according to a statement from Massachusetts General Hospital.
The hospital described the milestone as unprecedented for this type of procedure.
“His case represents the longest dialysis-free survival following porcine kidney xenotransplantation in a living human and the first transition to human kidney transplantation,” Massachusetts General Hospital said in its statement.
Since receiving the human donor kidney, Andrews said his recovery has exceeded his expectations, offering him a dramatically extended life expectancy compared with where he stood a year and a half earlier.
“We could be talking decades,” said Andrews, a father of three adult children ranging in age from 40 to 46. “It’s running perfect. I mean, the thing is perfect.”
Andrews said the experience of nearly losing his life has left him with a renewed appreciation for everyday moments he previously took for granted, including simple pleasures like smelling flowers, swimming, riding a bike and fishing.
“Every day I wake up, I’m like, this is another extra day because I should have been dead a year ago or more,” Andrews said.
Andrews said he knows little about the donor of his human kidney, aside from the fact that the donor was a young man who enjoyed blueberries, a fruit Andrews said he had never particularly cared for during the first six decades of his own life but has since developed an unexpected fondness for. Reflecting on the donor’s death, Andrews grew emotional discussing the weight of having received the organ.
“To know that somebody died way younger and I’m living because of it, that’s pretty tough,” Andrews said, his voice trailing off. “I have this new kidney in me and I need to honor it.”
Riella, who has led Mass General’s broader xenotransplantation research effort, said the underlying motivation behind the research remains addressing a persistent and severe shortage of available human donor organs.
“The organ shortage is the greatest crisis we have right now in transplantation,” Riella wrote in comments accompanying the study’s publication. “We know that the best treatment option for patients with end-stage kidney disease who have developed renal failure is transplantation, but we simply don’t have enough human organs to transplant in a timely manner.”
More than 100,000 people currently sit on the national organ transplant waiting list in the United States, with the vast majority of those patients waiting specifically for a kidney, according to figures cited by NBC News.
Andrews’ case builds on earlier progress in the field. Towana Looney, 55, previously lived with a pig kidney for what was then a record 130 days before her body began rejecting the organ, requiring its removal in April 2025. Looney remains alive and on dialysis while she awaits a matching human donor, according to a representative for NYU Langone Health.
Riella described the broader vision behind the research as using pig kidneys primarily as a temporary bridge for patients awaiting a compatible human donor organ, rather than necessarily as a permanent, standalone replacement.
“Our vision is that xenotransplantation could help address this gap — initially as a bridge to get patients off dialysis while they wait for a human donor kidney, and potentially, as we establish long-term safety and durability, as a destination therapy in its own right,” Riella said.
Andrews said his own conversations with Riella and the broader research team have reflected a rapidly shifting timeline for when the procedure might become more widely available to patients facing similar circumstances.
“When we talked the first time and I met Dr. Riella, they were talking about at least 10 years, that it’s going to be at least 10 years before this becomes viable — now they’re talking about five years or less than five years,” Andrews said, adding that he believes he “may live to see it” become a routine medical procedure.
Andrews’ successful outcome follows Mass General’s first pig-to-human kidney transplant in 2024, performed on patient Richard “Rick” Slayman, who survived 52 days before dying of cardiac causes the hospital said were unrelated to the transplant itself, with his pig kidney reportedly still functioning at the time of his death.
Andrews said learning about Slayman’s case before his own procedure gave him a measure of cautious optimism heading into his own transplant.
“I read about it and they told me he died, but he died of other causes, the kidney was still working,” Andrews said. “I said, ‘Huh, you know what? I think this might work.’”
Business
Fuel tanker explosion after traffic accident kills 10 in Western Iran, state media says

Fuel tanker explosion after traffic accident kills 10 in Western Iran, state media says
Business
Federal appeals court upholds ban on Trump’s bid to use citizenship data for voter checks

Federal appeals court upholds ban on Trump’s bid to use citizenship data for voter checks
Business
Why I Would Invest In QVOL Instead Of JEPQ (NASDAQ:QVOL)
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Business
The Most Divided Fed In A Decade Is About To Vote (NYSEARCA:SPY)
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Analyst’s Disclosure: I/we have a beneficial long position in the shares of SPY, QQQ, MSFT, META, AMZN, AAPL, NVDA, AMD either through stock ownership, options, or other derivatives. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.
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Business
Wells Fargo: Stick To High-Yield Preferred Shares During Interest Rate Volatility
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Seeking Alpha’s Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.
Business
Retired FBI Agent Theorizes Nancy Guthrie May Have Suffered Fatal Heart Attack After Abduction
TUCSON, Ariz. — A retired FBI agent has put forward a new theory about the disappearance of Nancy Guthrie, suggesting the 84-year-old mother of “Today” show co-host Savannah Guthrie may have suffered a fatal heart attack shortly after being abducted from her Arizona home more than seven months ago.
Frank Storey, a retired FBI agent, discussed the case during an appearance on retired FBI agent Jennifer Coffindaffer’s “True Crime With Jen Coffindaffer” podcast on Sept. 2. Storey theorized that the abduction may have initially begun as a kidnapping for ransom that later went wrong, with Nancy Guthrie potentially suffering a fatal heart attack a day or two after being taken from her home.
Nancy Guthrie disappeared from her home in the Catalina Foothills area of Tucson in the early hours of Feb. 1, 2026. She was last seen at her home the evening before, after being dropped off by family members. Seven months later, authorities have not publicly named a suspect and have not determined what ultimately happened to her.
Despite the lack of confirmed answers, Storey expressed confidence that the case would eventually be resolved.
“I think it will be at some point. Somewhere along the line, somebody always talks,” Storey said.
Storey suggested that if more than one person was involved in Nancy Guthrie’s disappearance, it remains possible that one of those individuals could eventually be arrested for an unrelated serious crime and choose to cooperate with investigators in order to reduce their own legal exposure in that separate matter.
“That may occur; it may not. But it’s possible,” Storey added, while stressing that his comments reflected only his personal theory rather than any official finding in the case.
Storey’s comments come amid separate claims from a friend of Nancy Guthrie’s that the investigation has effectively gone cold, a characterization that has not been confirmed by investigators and stands in direct contrast to public statements from law enforcement overseeing the case.
Investigators have previously released doorbell camera footage appearing to show an armed, masked individual tampering with a camera at Nancy Guthrie’s front door around the time of her disappearance. Pima County Sheriff Chris Nanos said in July that investigators had not yet established whether that individual acted alone or with assistance from others.
A communication released by the Pima County Sheriff’s Department on July 31 also indicated that Nancy Guthrie had died shortly after being taken from her home. That message, sent days after her initial disappearance, was released publicly alongside an earlier ransom demand as part of an effort by investigators to generate additional leads and tips from the public. Authorities have not formally confirmed the claim that Nancy Guthrie is deceased.
Investigators have continued examining physical evidence recovered from Nancy Guthrie’s home in the months since her disappearance. According to Sheriff Nanos, testing on a hair sample recovered from the scene has been completed without producing a viable lead toward identifying a suspect. Separately, a mixed DNA sample containing genetic material from as many as four different individuals remains under active examination by multiple forensic laboratories, including the FBI’s laboratory in Quantico, Virginia.
Authorities have not publicly confirmed whether they believe Nancy Guthrie is alive or deceased as the investigation continues. Sheriff Nanos has repeatedly pushed back against suggestions that the case has gone cold or that investigators have stopped actively pursuing leads.
“This case is not cold,” Nanos has said in addressing public concerns about the pace of the investigation.
The disappearance of Nancy Guthrie has drawn sustained national attention given her connection to her daughter, one of the most recognizable figures in American television news. Despite that heightened public interest, the Pima County Sheriff’s Department has continued to withhold detailed regular updates on the investigation’s progress, a practice officials have defended as consistent with standard law enforcement procedure in an active, ongoing case involving potential criminal activity.
Storey’s theory adds to a range of speculative explanations that have circulated publicly in the months since Nancy Guthrie’s disappearance, none of which have been confirmed by investigators. Retired law enforcement officials and commentators covering the case have offered varying perspectives on what may have happened, though the Pima County Sheriff’s Department has continued to emphasize that its investigation remains active and that specific details are being withheld deliberately as part of the ongoing inquiry.
Investigators have previously said DNA and video analysis efforts remain ongoing with support from laboratories across the country, and have continued to encourage members of the public with any credible information related to the case to come forward. Authorities have established tip lines through both the Pima County Sheriff’s Department and the FBI to help facilitate the submission of any new information that could assist the investigation.
As the case approaches its eighth month without a named suspect or confirmed resolution, theories like the one offered by Storey continue to circulate publicly even as investigators maintain that the underlying facts of what happened to Nancy Guthrie remain unconfirmed. Sheriff Nanos has indicated that the department will continue withholding a formal press conference on the case until investigators have a significant development to share publicly, leaving both Nancy Guthrie’s family and the broader public that has followed the case to await further updates as the investigation continues.
Business
Japanese stocks face continued risk aversion despite record profits, Nomura says

Japanese stocks face continued risk aversion despite record profits, Nomura says
Business
Cathay Pacific Marks 80 Years Since First Flight, From Converted Cargo Plane To Global Airline
HONG KONG — Cathay Pacific is celebrating 80 years since its founding, tracing a journey that began with a single converted cargo aircraft in the aftermath of World War II and has since grown into one of Asia’s most recognized commercial airlines, serving more than 100 destinations worldwide.
The airline’s origins date to 1946, when former Air Force pilots Roy Farrell and Sydney de Kantzow set out to establish a cargo route flying goods from Australia to Shanghai. Cathay Pacific Airways was officially registered in Hong Kong for HK$2 on Sept. 23, 1946, and the company operated its first flight just one day later, on Sept. 24, from Sydney to Hong Kong. The airline’s entire fleet at the time consisted of a single aircraft, a converted Douglas DC-3 affectionately nicknamed “Betsy.”
Cathay Pacific Group CEO Ronald Lam reflected on the airline’s founding mission and its enduring relevance eight decades later.
“Since our earliest days, Cathay Pacific has helped open new horizons for people, businesses and communities,” Lam said. “That purpose has defined our first 80 years, and it continues to guide us today.”
The airline’s expansion accelerated through the following decades. In the 1960s, Cathay Pacific’s Convair 880 jetliners extended the airline’s network across Asia to destinations including Seoul and Kota Kinabalu, as jet-powered aircraft made air travel faster and more accessible than the propeller-driven planes that preceded them. On Oct. 19, 1964, the airline welcomed its millionth passenger aboard a flight between Singapore and Bangkok.
A significant turning point came in 1979 with the arrival of Cathay Pacific’s first Boeing 747, which extended the airline’s reach well beyond the Asia-Pacific region and laid the groundwork for a truly global route network. The following year, the airline launched its first service to London, marking its formal entry into long-haul intercontinental travel.
Throughout the 1980s, Cathay Pacific’s Boeing 747 aircraft, painted in the airline’s now-iconic green-and-white striped livery often referred to as the “lettuce leaf sandwich” design, became a familiar sight over Kowloon as they approached Hong Kong’s former Kai Tak Airport, serving as an enduring symbol of the city’s connection to the broader world. That decade also brought the expansion of passenger services to mainland China, beginning with Shanghai in 1980. In 1983, Cathay Pacific became the first airline in Asia to offer first class, business class and economy class cabins aboard the same aircraft, establishing a new industry benchmark for passenger service tiers. Three years later, coinciding with the airline’s 40th anniversary, Cathay Pacific became the first company to list on Hong Kong’s newly unified stock exchange.
The airline also built a reputation for pioneering in-flight passenger technology during this period. In 1991, Cathay Pacific became the first airline to introduce live radio broadcasts on board, delivering music and news content directly to passengers during flights. Seatback entertainment systems followed shortly after, arriving first in first class in 1992 before expanding across all cabin classes by 1996.
One of the airline’s most significant operational transitions came in 1998, when Hong Kong’s aviation infrastructure shifted from the historic but constrained Kai Tak Airport to the newly built Hong Kong International Airport at Chek Lap Kok. On July 5, 1998, Cathay Pacific flight CX251 to London Heathrow became the final flight to depart Kai Tak. The following morning, flight CX889, dubbed “Polar One,” landed at the newly opened Hong Kong International Airport, having completed the first non-stop passenger service between New York and Hong Kong, and at the time, the longest non-stop commercial flight route in operation anywhere in the world. That same year, Cathay Pacific took delivery of its first Boeing 777-300, an aircraft that would go on to form the backbone of its long-haul fleet for years to come.
The airline’s fleet modernization has continued into more recent years, with the arrival of the Airbus A350 in 2016 ushering in a new era of fuel efficiency and passenger comfort. More recently, Cathay Pacific has introduced updated cabin products across selected Boeing 777-300ER aircraft, refreshing its business, premium economy and economy class designs as part of its continued evolution of the passenger experience.
Cargo operations have also played a central role in Cathay Pacific’s growth. The airline’s first dedicated freighter aircraft began operations in 1976, with cargo becoming an increasingly important pillar of the business through the 2000s. The HK$5.9 billion Cathay Cargo Terminal entered full operation in 2013, establishing itself as one of the world’s largest and most technologically advanced air cargo facilities and cementing Hong Kong’s position as a leading international air freight hub. Today, Cathay Cargo transports approximately 1.7 million tonnes of cargo annually.
The airline has continued expanding its global route network in recent years, setting a record for its longest-ever route with the launch of service to Dallas-Fort Worth in April 2025. Cathay Pacific’s network now spans more than 100 destinations worldwide, recently strengthened by new routes to Urumqi, Munich and Seattle, with service to Almaty set to join the network in 2027.
Beyond its route expansion, Cathay Pacific has continued investing in its onboard passenger experience, introducing new Airbus A321neo aircraft featuring enhanced comfort and entertainment options, alongside its acclaimed Aria Suite business class product and refreshed premium economy and economy cabins across selected Boeing 777-300ER aircraft. The airline has said its refreshed economy cabins and a new Aria Studio business class product will soon debut aboard its Airbus A330-300 fleet, marking the next phase of its regional cabin upgrades.
As Cathay Pacific has evolved into what the company describes as a broader travel lifestyle brand, it has expanded beyond air travel into a range of additional consumer offerings, including dining, shopping and wellness experiences, alongside deeper integration with transportation links across China’s Greater Bay Area region. The airline has also emphasized its ongoing commitment to sustainability, citing continued investment in newer, more fuel-efficient aircraft, emissions-reduction measures across its operations, and an accelerated adoption of sustainable aviation fuel as part of its broader environmental strategy.
Reflecting on the airline’s 80-year milestone, Lam emphasized Cathay Pacific’s deep ties to its home city and the broader region it has served since its founding.
“As we celebrate 80 Years Together, we do so with gratitude for everyone who’s been part of our journey,” Lam said. “Cathay Pacific’s story is inseparable from Hong Kong, from our deep connections to the Chinese Mainland and from our place in the wider world. Our responsibility now is to honour that legacy by building on it, so future generations can continue to discover the joy of travel.”
Business
OpenAI acknowledges ’wiki incident’ and need for more transparency around unintended AI behavior

OpenAI acknowledges ’wiki incident’ and need for more transparency around unintended AI behavior
Business
Oracle, Adobe Results In Focus As Earnings Season Winds Down
Get ahead of the market by subscribing to Seeking Alpha’s Wall Street Week Ahead, a preview of key events scheduled for the coming week. The newsletter keeps you informed of the biggest stories set to make headlines, including upcoming IPOs, investor days, earnings reports, and conference presentations.
The stock market fell on Friday as nonfarm payrolls surpassed expectations in August. U.S. nonfarm payrolls increased by 162K vs. +55K consensus and +21K in the prior month (revised from -23K), according to data released by the U.S. Bureau of Labor Statistics on Friday.
The economic calendar is relatively lighter for the upcoming holiday-shortened week, with markets closed on September 7 in observance of Labor Day. There are no major data scheduled for Tuesday and Wednesday. On Thursday, PPI data for August and initial jobless claims numbers will be released, with CPI data for the month scheduled for Friday.
______________________________________________________________
Earnings spotlight: Thursday: Oracle (ORCL), Adobe (ADBE). See the full earnings calendar.
Earnings spotlight: Friday: Kroger (KR). See the full earnings calendar.
Volatility watch: Carvana (CVNA) and GameStop (GME) have seen options volatility increase over the last week. The most overbought stocks per their 14-day Relative Strength Index include Crinetics Pharma (CRNX) and Varex Imaging (VREX). The most oversold stocks per their 14-day Relative Strength Index include TJX (TJX) and DICK’S Sporting (DKS). Short interest is elevated on Xponential Fitness (XPOF) and Recursion Pharmaceuticals (RXRX).
Dividend watch: Companies that have an ex-dividend date coming next week include Cigna (CI), HP Inc. (HPQ), Nvidia (NVDA), and Chubb (CB).
Oracle Earnings Preview: Oracle is scheduled to announce first-quarter results next week with consensus pointing towards earnings of $1.74 per share on revenue of $19.13B. Analysts are expecting another double-beat from Oracle and likely stronger-than-anticipated guidance projections, with an overall positive tone from the management team. They will keenly watch for
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