Business
Strict Regulatory Frameworks Vs The Need For Rapid Digital Innovation
Online businesses in the UK are expected to move quickly. New tools, AI systems and cloud services appear almost daily, and companies that hesitate risk falling behind competitors.
At the same time, the regulatory landscape is becoming more demanding, forcing businesses to slow down and consider compliance before rolling out new features.
This tension is particularly critical for the backbone of the British economy. UK SMEs numbered 5.49 million in 2024, representing 99.8% of all private sector businesses. These smaller entities often lack the dedicated legal departments and compliance officers that their blue-chip counterparts possess, yet they are held to similar standards regarding data protection, financial reporting, and operational resilience. The conflict between the need for speed and the requirement for safety has become the defining operational struggle of 2026.
The UK’s Expanding Online Regulations
Recent legislation shows how much the environment is changing. New duties under the Online Safety Act came into force in January 2026, placing stronger obligations on digital platforms to monitor toxic content, carry out formal risk assessments and document how their services manage online safety. For companies building social platforms, messaging tools or recommendation systems, compliance can no longer be treated as an afterthought.
The Data (Use and Access) Act 2025 is being phased in across 2025 and 2026. The law introduces new frameworks around smart data sharing, digital identity and updated rules for how organisations handle personal data. While parts of the reform are designed to support innovation, they also add new governance and reporting requirements that businesses must keep up with.
Similar pressures can be seen in highly regulated digital industries such as online gambling. Recent UK reforms have introduced stronger affordability checks, forcing operators to redesign payment systems, onboarding processes and promotional tools to remain compliant. Additionally, new LCCP SR Code 5.1.1 rules on promotions ban “mixed‑product” offers such as “bet on sports, get free spins,” and cap wagering requirements on bonuses; these apply to sports‑betting promos.
However, this also shows that the competitive environment in online marketplaces may also change as a result of regulatory tightening. Many globally based platforms operate under various legal frameworks and so offer larger betting markets or fewer product limitations and are not subject to the country’s self-exclusion program (source: https://www.gamblinginsider.com/uk/non-gamstop-betting-sites). UK-licensed operators must adjust to stake limits, affordability checks, and tougher advertising guidelines. This leads to a scenario where customer choice and product design are influenced by regulatory protections. In actuality, it draws attention to the continuous conflict between preserving a competitive atmosphere that still encourages innovation and safeguarding users through regulation.
While these measures are intended to strengthen consumer protection, they also showhow digital businesses must constantly adapt their technology and product design to operate within evolving legal frameworks.
Taken together, these changes illustrate the balancing act facing many digital firms. Innovation is still encouraged, but it now happens within a much denser network of rules covering data use, online safety and consumer protection.
Rising Compliance Costs Challenge Small Business Scalability
The administrative burden placed on growing companies has moved from a periodic annoyance to a constant operational drag. Before, compliance was often a box-ticking exercise conducted annually, but today’s digital-first environment demands continuous monitoring. Regulations such as the Digital Operational Resilience Act (DORA) and strict ICO data enforcement mean that businesses must constantly prove their cyber posture.
This redirects critical resources away from research and development. It forces founders to choose between hiring a new developer to build features or a compliance manager to ensure those features do not violate emerging protocols.
Nowhere is this contention more apparent than in the government’s own incentive schemes designed to foster growth. While tax reliefs are intended to fuel innovation, the complexity of accessing them has created a barrier for many legitimate businesses. For the 2022-2023 tax year, 62,015 SMEs made R&D tax relief claims, with the majority coming from information & communication and manufacturing sectors.
However, the administrative layers added to prevent fraud have inadvertently slowed down the funding cycle for honest innovators. When the cost of compliance begins to approach the value of the incentive itself, businesses naturally pull back on the risky, forward-thinking projects that the economy desperately needs to thrive.
Strategies For Maintaining Agility Amidst Bureaucratic Constraints
To survive heavy regulation, successful SMEs are changing how they view compliance. Rather than treating it as a final hurdle to clear before launch, forward-thinking leaders are integrating “compliance by design” into their workflows. This involves using automated regulatory technology (RegTech) that can monitor data flows and report anomalies in real-time, effectively outsourcing the heavy lifting to software.
By automating the evidence-gathering process, businesses can free up their human talent to focus on creative problem-solving and strategic growth, ensuring that innovation continues despite the red tape.
The relationship between large enterprises and their smaller suppliers will most likely dictate the pace of digital adoption. Large corporations are increasingly pushing their own regulatory obligations down the supply chain, demanding that their vendors meet the same high standards they do.
New regulations mean SMEs must provide real-time security evidence to larger clients, moving beyond annual audits to 24/7 resilience demonstrations by 2026. For the UK’s small business community, the path forward involves embracing these standards not as burdens, but as quality markers that can unlock lucrative contracts in a risk-averse world.
Business
Form 4 Perimeter Solutions SA For: 7 March

Form 4 Perimeter Solutions SA For: 7 March
Business
Form 4 OFG Bancorp For: 7 March

Form 4 OFG Bancorp For: 7 March
Business
IdeaForge, Sedemac and more: With 2 more listings in pipeline, how IIT Bombay is churning out IPO multibaggers
Through its incubator, the Society for Innovation and Entrepreneurship (SINE), IIT Bombay has already seen significant gains from startup listings such as ideaForge and is now poised for another windfall from the IPO of Sedemac Mechatronics.
With companies like Atomberg Technologies and Gupshup also exploring public listings, the institute’s long association with technology startups is beginning to deliver substantial financial returns.
ideaForge: Early success story
One of the earliest examples of this success is ideaForge Technology, India’s leading drone manufacturer. The company was founded in 2006 by IIT Bombay alumni Ankit Mehta, Rahul Singh and Ashish Bhat and was incubated at SINE during its formative years.
ideaForge launched its IPO in July 2023 and the issue drew massive investor interest, being subscribed about 106 times. The stock listed at a strong premium, briefly doubling shareholder wealth on its debut.
For SINE, the listing translated into a meaningful monetisation opportunity. The incubator held roughly 1 lakh shares in the company prior to the IPO. At the upper end of the IPO price band of Rs 672 per share, the value of that stake was estimated at around Rs 6-7 crore.
SINE partially exited during the offer for sale, selling about 22,600 shares and realising roughly Rs 1.52 crore from the transaction, while continuing to retain a stake in the company.
Sedemac: A much larger windfall
The institute is now set to benefit even more from the IPO of Sedemac Mechatronics, another startup that emerged from the IIT Bombay ecosystem.
Sedemac was founded in 2007 by Shashikanth Suryanarayanan, an associate professor in the institute’s mechanical engineering department, along with other early team members who were students or researchers associated with the campus.
The company has grown into a manufacturer of electronic control units and genset controllers used across two-wheelers, electric vehicles and industrial applications.
SINE backed the company in its early stages and currently holds 4.08 lakh shares, representing about 0.92% stake.
At the upper end of the IPO price band of Rs 1,352 per share, the value of SINE’s holding stands at roughly Rs 55 crore.
As part of the offer for sale, the incubator plans to sell 2.04 lakh shares. At the IPO price, this portion alone would fetch around Rs 27.58 crore.
The scale of the return is remarkable given the acquisition price. SINE acquired the shares at an average cost of Rs 0.01 each, meaning the 2.04 lakh shares being sold cost only about Rs 2,040.
At the IPO price, the sale implies a gain of about Rs 27.58 crore and a return of roughly 1.3 lakh times the original investment. Even after the partial exit, SINE will continue to hold another 2.04 lakh shares in the company, leaving it with a residual stake worth roughly Rs 27-28 crore at the IPO price.
More IPO candidates emerging
The IIT Bombay startup ecosystem could see more companies head to the stock market in the coming years.
Consumer appliances company Atomberg Technologies is among the startups exploring a public listing. The Temasek-backed firm is weighing an IPO in Mumbai that could raise around $200 million, according to Bloomberg.
Founded in 2012 by IIT Bombay alumni Manoj Meena and Sibabrata Das, Atomberg began by manufacturing energy-efficient ceiling fans and has since expanded into products such as mixer grinders, water purifiers and smart locks.
The company has attracted several prominent investors over the years. In 2023 it raised $86 million in funding from Temasek, Steadview Capital, Jungle Ventures and Inflexor Ventures.
Another startup with links to IIT Bombay’s incubation ecosystem is Gupshup, a conversational messaging platform founded by Beerud Sheth.
The company received early incubation support from SINE during its formative years and has since grown into one of the world’s largest messaging platforms for businesses.
Gupshup recently raised $60 million in fresh funding from Globespan Capital Partners along with debt financing from EvolutionX Debt Capital. The San Francisco-headquartered firm is also considering shifting its domicile to India ahead of a potential public listing in the country within the next one to two years.
Founded in 2004, Gupshup processes more than 120 billion messages annually for over 50,000 businesses across 130 countries.
From campus labs to public markets
For IIT Bombay, the growing list of IPO-bound startups highlights how academic incubation programs are increasingly shaping India’s startup economy. Through SINE, the institute has supported hundreds of early-stage ventures over the past two decades. While many remain private, a handful are now reaching a stage where they can tap public markets.
As companies like Sedemac, Atomberg and potentially Gupshup move closer to listing, IIT Bombay’s long-running experiment with technology incubation is beginning to translate into tangible financial returns alongside entrepreneurial success.
(Disclaimer: Recommendations, suggestions, views and opinions given by the experts are their own. These do not represent the views of Economic Times)
Business
Form 144 Madrigal Pharmaceuticals For: 7 March

Form 144 Madrigal Pharmaceuticals For: 7 March
Business
Krishnan Krish S, president of Krystal Biotech, sells $6.58 million in KRYS stock

Krishnan Krish S, president of Krystal Biotech, sells $6.58 million in KRYS stock
Business
Iovance Biotherapeutics (IOVA) Stock Rallies on Analyst Upgrades, Amtagvi Momentum
SAN CARLOS, Calif. — Shares of **Iovance Biotherapeutics Inc.** (NASDAQ: IOVA) climbed sharply in early March 2026 trading, fueled by renewed analyst optimism and ongoing commercial progress for its flagship tumor-infiltrating lymphocyte (TIL) therapy, **Amtagvi** (lifileucel). The biotech company’s stock, which has hovered in the low single digits for much of the year, gained traction after multiple price target increases and positive commentary on its revenue trajectory.

As of March 7, 2026, IOVA closed at approximately $5.13, up from recent lows around $4.58, with intraday highs reaching $5.16 in heavy volume sessions. The stock has seen notable volatility, trading in a 52-week range from $1.64 to $5.16, reflecting broader biotech sector pressures but also bursts of enthusiasm tied to clinical and commercial milestones.
The latest catalyst came from UBS, which raised its price target on IOVA from $2 to $4, citing strong fourth-quarter revenue growth for Amtagvi despite a challenging market environment. Other firms followed suit: Baird increased its target to $4 from $3, Barclays to $11 from $10, and Citizens upgraded the stock to Outperform from Market Perform. These adjustments highlight growing confidence in Iovance’s ability to scale its pioneering TIL platform beyond advanced melanoma.
Amtagvi, the first FDA-approved TIL therapy, received accelerated approval in February 2024 for adult patients with unresectable or metastatic melanoma previously treated with other therapies. The personalized cell therapy, manufactured from a patient’s own tumor tissue, has driven rapid revenue ramp-up in its first full commercial year.
Iovance reported preliminary full-year 2025 product revenue of approximately $264 million, within its guided range of $250 million to $300 million. This marked a 61% increase from 2024’s $164.1 million, largely propelled by Amtagvi’s U.S. sales of about $220 million and global Proleukin (aldesleukin) contributions of roughly $44 million. Fourth-quarter product revenue hit $86.8 million, up about 30% sequentially, with gross margins improving to around 50% as manufacturing efficiencies took hold.
Management emphasized accelerating demand through an expanding network of authorized treatment centers (ATCs), faster production turnaround times (32 days or less), and supportive real-world data demonstrating durable responses in advanced melanoma. In a February 2026 earnings update, executives described 2026 as poised for “remarkable” revenue growth, with detailed U.S. product guidance forthcoming soon. Long-term goals include gross margins approaching 70% through full internalization of lifileucel manufacturing.
Pipeline advancements further bolster the bullish case. On February 24, 2026, Iovance announced positive early results from the first clinical trial of lifileucel in soft tissue sarcomas, specifically undifferentiated pleomorphic sarcoma (UPS) and dedifferentiated liposarcoma (DDLPS). The study showed a 50% confirmed objective response rate, prompting plans for a registrational trial. The data, presented at scientific meetings, sparked a 25%+ single-day stock surge earlier in the year.
In non-small cell lung cancer (NSCLC), lifileucel earned FDA Fast Track designation for second-line advanced non-squamous NSCLC, supported by interim data showing a 26% objective response rate and durable benefit compared to standard docetaxel. Management targets a supplemental biologics license application (sBLA) and potential accelerated approval/launch in the second half of 2027, eyeing a multibillion-dollar U.S. peak sales opportunity in lung cancer—potentially seven times larger than melanoma.
Additional trials explore frontline melanoma combinations (TILVANCE-301), second-line NSCLC (IOV-LUN-202), endometrial cancer (IOV-END-201), and next-generation engineered TIL therapies like IOV-5001, with an IND submission planned for the first half of 2026. International regulatory progress includes priority reviews in Australia and recommendations in Switzerland, with decisions expected in early 2026.
Financially, Iovance ended 2025 with about $303 million in cash, providing runway into the third quarter of 2027. Full-year costs and expenses totaled around $667 million, resulting in a net loss of $391 million, or $1.09 per share—improvements over prior periods but underscoring the cash-intensive nature of commercial-scale cell therapy.
Analysts maintain a mixed but increasingly positive consensus, with average price targets around $9–$10 implying substantial upside from current levels. High-risk elements persist: competition in solid tumors, manufacturing complexities, and the need for consistent revenue scaling amid biotech funding challenges. Yet, Iovance’s leadership in TIL therapy positions it as a potential platform player if label expansions materialize.
Upcoming investor visibility includes presentations at the TD Cowen 46th Annual Healthcare Conference on March 2 and the Barclays 28th Annual Global Healthcare Conference on March 11, where leadership will likely discuss growth drivers and 2026 guidance.
As Iovance transitions from launch-year execution to multi-indication expansion, the stock’s performance hinges on Amtagvi’s sustained momentum and pipeline catalysts. Investors watch closely for first-quarter 2026 results, expected in May, which could provide clearer visibility into the year’s trajectory.
With its innovative approach to solid tumor immunotherapy and accelerating commercial story, Iovance Biotherapeutics remains a high-conviction name in the biotech space amid 2026’s evolving oncology landscape.
Business
Starting late in mutual funds? Expert shares a Rs 40,000 SIP portfolio strategy for a 50-year-old
This was highlighted in a recent investor query from Dhiraj Kumar, a 50-year-old professional, an investor and a viewer of The Money Show on ET Now, who wants to start investing Rs 40,000 per month in mutual funds. He described himself as someone who is not familiar with handling market risk and prefers a portfolio with moderate risk.
Also Read | Women hold just 25% of mutual fund folios, start investing 5 years later than men: Report
Responding to the query, Pankaj Mathpal, CEO of Optima Money Managers, said that while understanding market risk is important, mutual funds are managed by professional fund managers who actively manage investments and attempt to control risk within the scheme’s mandate.
“As he does not know how to manage market risk, that is very, very important. But the most important thing is that when you invest in a mutual fund, you have to understand that fund managers are also doing that job for you. They are trying to manage the risk but, at the same time, selection of funds should be proper and schemes you select should be suitable as per your financial goals,” Mathpal said.
According to Mathpal, investors should focus on selecting the right mix of funds based on their financial goals and investment horizon. In this case, the investor did not specify a target corpus or a specific financial goal. However, given his age, Mathpal assumed that he could be investing for at least five years or possibly longer.
For someone new to equity-linked investments and looking for moderate risk, he suggested beginning with a combination of hybrid and diversified equity funds.
“To start with, some hybrid funds like multi-asset allocation or dynamic asset allocation funds, flexi cap fund and an index fund can be a good starting point for him,” the expert said.
Mathpal recommended starting with schemes such as ICICI Prudential Balanced Advantage Fund, WhiteOak Capital Multi Asset Allocation Fund, HDFC Flexi Cap Fund, and SBI Nifty Index Fund. These funds represent different investment styles, including dynamic asset allocation, multi-asset exposure, actively managed diversified equity and passive index investing.
Also Read | Women’s Day 2026: India’s leading 3 female portfolio managers. Check how they navigate market cycles
Hybrid funds such as balanced advantage or multi-asset allocation funds can help moderate risk by spreading investments across different asset classes like equities, debt and commodities. Flexi-cap funds offer diversification by allowing fund managers to invest across large-cap, mid-cap and small-cap companies depending on market opportunities. Meanwhile, index funds provide low-cost exposure to broader markets by tracking benchmark indices.
Mathpal also highlighted an important behavioural aspect for new investors: patience. With markets expected to remain volatile at times, he advised investors not to track their portfolios too frequently.
Instead, investors should remain disciplined with their investments and review their portfolios periodically rather than reacting to short-term market movements. “Once you start investing, have patience, keep investing and once in a year you can review your portfolio, but your goal should be long term,” he said.
For investors starting later in life, consistency and realistic expectations become even more important. A structured SIP approach, a diversified portfolio and regular but not excessive monitoring can help investors gradually build wealth over time while managing market volatility.
One should always consider their risk appetite, investment horizon and goals before making any investment decision.
(Disclaimer: Recommendations, suggestions, views and opinions given by the experts are their own. These do not represent the views of The Economic Times)
If you have any mutual fund queries, message on ET Mutual Funds on Facebook/Twitter. We will get it answered by our panel of experts. Do share your questions on ETMFqueries@timesinternet.in alongwith your age, risk profile, and twitter handle
Business
Bilibili: A Deep Dive Into The 299% Operating Income Surge And New Valuation
Bilibili: A Deep Dive Into The 299% Operating Income Surge And New Valuation
Business
Kalshi sued over $54M Iran leader bets after ‘death carveout’
Kalshi co-founder Tarek Mansour says the company wants to give people what they desire on ‘The Claman Countdown.’
Kalshi is facing a $54 million class action lawsuit after traders accused the prediction market of invoking a “death carveout” clause to avoid paying bets tied to the killing of Iran’s supreme leader, according to reporting from Reuters.
Kalshi was sued in federal court Thursday over contracts that asked whether Ayatollah Ali Khamenei would leave office before March 1, 2026, according to a class action complaint.
Khamenei, 85, was killed Saturday in U.S.-Israeli strikes that left hundreds dead, including top Iranian officials. The strikes occurred under Operation Epic Fury.
The lawsuit says customers were drawn to what it calls the “Khamenei Market” because of the shifting geopolitical situation with Iran’s leadership. It alleges that, after Khamenei was killed, Kalshi invoked a “death carveout” provision to avoid paying customers what they were owed.
JUDGE BLOCKS META FROM INTRODUCING ‘EXAGGERATED’ CLAIMS IN SOCIAL MEDIA TRIAL

Iranian Supreme Leader Ali Khamenei addresses the nation in a state television broadcast June 18, 2025, in Tehran, Iran. (Office of the Supreme Leader of Iran via Getty Images / Getty Images)
“With an American naval armada amassed on Iran’s doorstep and military conflict not merely foreseeable but widely anticipated, consumers understood that the most likely — and in many cases the only realistic — mechanism by which an 85-year-old autocratic leader would ‘leave office’ was through his death,” the lawsuit states.
“Defendants understood this as well.”
The complaint argues the contract language was “clear, unambiguous and binary” and accuses Kalshi of “deceptive” and “predatory” conduct.
APPLE IMPLEMENTING AGE VERIFICATION TOOL TO ENSURE USERS ARE 18 AND UP FOR SOME APPS

A billboard for Kalshi showing 2024 U.S. presidential election odds across from the Nasdaq MarketSite in New York Nov. 6, 2024. (Michael Nagle/Bloomberg via Getty Images / Getty Images)
The lawsuit was filed in the U.S. District Court for the Central District of California.
The company’s CEO, Tarek Mansour, on Saturday defended the “death carveout,” saying it “keeps the rules simple.” He also said Kalshi would reimburse all fees from the Khamenei market.
Prediction markets have exploded in popularity since the 2024 U.S. election, when their real-time probabilities proved more accurate than polling in forecasting Donald Trump’s victory, according to Reuters.

Two Iranian-made unmanned aerial vehicles are displayed at Azadi Square during a rally to mark the 44th anniversary of the victory of Iran’s 1979 Islamic Revolution, in Tehran, Iran, Feb. 11, 2023. (Morteza Nikoubazl/NurPhoto via Getty Images / Getty Images)
Platforms like Kalshi offer tradable yes-or-no contracts tied to real-world events ranging from politics and sports to the economy. Contracts typically cost between zero and 100 cents and pay out if a specified outcome is confirmed.
Kalshi did not immediately respond to FOX Business’ request for comment.
Reuters contributed to this reporting.
Business
Share of equity mutual funds in portfolio of women investor surge to 32% in 5 years : Report
The report further highlights that fixed deposits have seen their share in portfolios drop from 45% to 20% over five years. Alternatives (PMS/AIF) have grown from a negligible 3% to 7%.
Also Read | Is six mutual funds too many for monthly SIP of Rs 8,500? Here’s what experts suggest
Five years ago, the dominant pattern among Indian women investors was familiar: fixed deposits, gold, and property—the classic ‘safety-first’ portfolio. Today, the same cohort has migrated toward allocation-led, goal-mapped portfolios that include equity mutual funds, structured debt products, AIFs, PMS, and in some cases, global equities and private markets, the report further said.
While AI tools are entering the investment ecosystem, adoption among women investors remains measured.
The study finds that 35–50% of women investors either do not use AI tools or use them selectively, primarily for learning, monitoring and research insights. Importantly, final portfolio decisions continue to rely on human judgement and advisor guidance rather than automated recommendations.
This suggests that AI is emerging as an information and analytics layer within the investment process rather than a substitute for human decision-making.
The report further said that investors are increasingly adopting “bucket thinking” — organising portfolios around life goals such as safety, growth, liquidity and legacy rather than individual products — shifting the focus from “Which product should I buy?” to “What role should this asset play in my portfolio?”, with portfolio discipline increasingly guided by allocation frameworks and rules rather than market reactions.
Also Read | Sensex slips over 7% this year. Should mutual fund investors continue SIPs or hit pause?
Women investors are showing increasing maturity during market cycles. As of now, 75–90% of investors hold or review their investments during market corrections rather than exiting in panic. At the same time, around 55% selectively add capital during market dips, reflecting growing conviction and a longer-term approach to investing.
Women investors are also developing a more nuanced understanding of investment risk. Five years ago, risk was largely interpreted as loss of principal. Today it increasingly includes inflation erosion, failure to meet financial goals, portfolio drawdowns and recovery time, as well as governance risks within family wealth structures and this shift reflects growing financial awareness and investment sophistication across investor segments.
The report also said that women investors increasingly evaluate advisors based on transparency, proactive strategy, financial education and governance support, rather than simply product access and as a result, the advisor relationship is evolving from product distribution toward strategic partnership in portfolio construction and wealth governance.
Also Read | 62% women plan to invest in crypto in next 6–12 months; Bitcoin remains top entry asset: CoinSwitch
“Indian women investors are becoming more informed, confident and strategic in shaping their financial futures. Over the past five years we have seen a clear shift from buying individual financial products to building structured portfolios anchored around asset allocation and long-term goals,” said Ankur Punj MD- Business Head, Equirus Wealth.
Technology, including AI, is beginning to play a role in the learning and research process,” Punj further said.
(Disclaimer: Recommendations, suggestions, views and opinions given by the experts are their own. These do not represent the views of The Economic Times)
If you have any mutual fund queries, message on ET Mutual Funds on Facebook/Twitter. We will get it answered by our panel of experts. Do share your questions on ETMFqueries@timesinternet.in alongwith your age, risk profile, and twitter handle
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