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U.S. and India remain split on WTO e-commerce moratorium extension

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Zai Lab Limited (ZLAB) Discusses Intracranial Activity of a New Therapy in Small Cell Lung Cancer With Brain Metastases Transcript

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OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Zai Lab Limited (ZLAB) Discusses Intracranial Activity of a New Therapy in Small Cell Lung Cancer With Brain Metastases April 20, 2026 8:30 AM EDT

Company Participants

Rafael Amado – President and Head of Global Research & Development

Conference Call Participants

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Luis Paz-Ares
Rohit Thummalapalli
Jonathan Chang – Leerink Partners LLC, Research Division
Michael Yee – UBS Investment Bank, Research Division
Anupam Rama – JPMorgan Chase & Co, Research Division
Yigal Nochomovitz – Citigroup Inc., Research Division
Linhai Zhao – Goldman Sachs Group, Inc., Research Division

Presentation

Operator

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Hello, ladies and gentlemen. Thank you for standing by, and welcome to Zai Lab’s 2026 AACR Investor Call. [Operator Instructions] As a reminder, today’s call is being recorded.

It is now my pleasure to turn the floor over to Dr. Rafael Amado, Zai Lab’s President and Head of Global Research and Development. Please go ahead, sir.

Rafael Amado
President and Head of Global Research & Development

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Hi, everyone. Thank you so much for joining us today. I am Rafael Amado, Zai Lab’s President and Head of Global R&D. Before we begin, we will be making forward-looking statements today, and I ask you to review Slide 2 for further details.

Moving to Slide 3. I’m joined today by 2 outstanding clinical investigators. Dr. Luis Paz-Ares is a leader in lung cancer. He’s Chair of the Medical Oncology Department at the Hospital Universitario 12 de Octubre and Head of the Lung Cancer Unit at National Oncology Research Center in Madrid. Dr. Rohit Thummalapalli is an Assistant Attending Physician and Gastrointestinal Medical Oncologist at Memorial Sloan Kettering Cancer Center. He specializes in GI and neuroendocrine cancers. And on the next slide, the disclosure information for both doctors.

Moving to Slide 5. Here’s our agenda. Dr. Paz-Ares will present first-time intracranial data with zoci in small cell lung cancer, followed by Dr. Thummalapalli in neuroendocrine

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Bitcoin strongest since February amid mid-east hopes

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Bitcoin strongest since February amid mid-east hopes
Bitcoin rose to the highest level since early February after a flurry of comments from the US and Iran sparked optimism that the conflict in the Middle East may be heading toward a resolution.

The original cryptocurrency broke through the higher bound of the narrow range its been trading in since the war broke out in late February, topping $78,000 for the first time since February 3. Bitcoin rose as much as 4.1% to $78,343, before paring the increase.

Other digital assets also pushed higher, with Either strengthening 3.3% and XRP increasing 2.4% as part of a broader risk-on rally. Equities climbed after Iran announced that the Strait of Hormuz is now “completely open” for commercial traffic, prompting traders to take on more risk. Oil and the dollar tumbled.“The reopening of the Strait of Hormuz is the risk-on signal the global markets have been waiting for,” said Matt Mena, senior crypto research strategist at 21shares. “By removing one of the most significant geopolitical choke points in the world, Iran has effectively uncorked a massive wave of liquidity and investor confidence.”Still, the derivatives market show traders remain largely defensive. Funding rates for perpetual futures contracts, a key measure of whether leveraged traders are betting on higher or lower prices, were negative. Hefty premiums are also being paid for put options providing downside protections at $60,000 and $50,000, respectively.


“Reality is that the market needs Hormuz clarity and sustained institutional buying to break this range with conviction. Until then, the direction remains unclear., said Jasper De Maere, OTC trader at crypto market maker Wintermute “A sustained ceasefire screams bullish, but each week the Strait remains disrupted from today probably brings an exponentially worse outcome as shocks will start to ripple through supply chains and the global economy.”

454151744Agencies

At the same time, a growing number of catalysts are seen as emerging. Strategy Inc. has acquired $2.6 billion in Bitcoin in the past two weeks alone. Bohan Jiang, senior derivatives trader at FalconX, said that buying has helped to underpin the market. Shares of Strategy jumped as much as 16% on Friday, the biggest one-day increase since Feb. 6. Other crypto-related stocks also rallied, with Coinbase Global Inc. gained as much as 8% and Galaxy Digital Inc. up more than 10%.

Earlier in the week, Charles Schwab announced plans this week to launch spot crypto trading this year and suggested clients could allocate as much as 8.8% of a portfolio to Bitcoin. Goldman Sachs Group Inc. also filed for a Bitcoin ETF, its first direct push into the crypto investment space. And last week Morgan Stanley became the first major bank to launch its own Bitcoin-tracking ETF.

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The Gold Edge: ETF net inflows up 4.5x in FY26

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The Gold Edge: ETF net inflows up 4.5x in FY26
ET Intelligence Group: Net inflows into gold exchange-traded funds (ETFs) surged to a record ₹68,867 crore in FY26, lifting their share of overall mutual fund industry inflows to nearly 10%, sharply above the historical range of 1-3%. Amid heightened market volatility driven by geopolitical risks, net inflows jumped 364% year-on-year, or more than four-and-a-half times, marking the fastest growth across all mutual fund categories, including equity, debt and hybrid, according to Association of Mutual Funds in India (AMFI) data. The FY26 inflows far exceeded the earlier annual range of ₹700-15,000 crore, making it an exceptional year for gold ETFs.

In addition, the incremental inflows increased ₹54,015 crore in FY26 over the previous year compared with the earlier annual range of ₹2,500-10,000 crore. Other fund categories showed mixed trends in net inflows in FY26 year-on-year. Debt and equity funds recorded 84% and 17% decline, respectively. Index funds registered a 56% decline in inflows. In contrast, hybrid funds and other ETFs reported 30% and 65% increase in inflows.

Screenshot 2026-04-21 055625Agencies

The surge in inflows in gold ETFs was aided by gold prices and volatility in the stock market. Gold prices surged about 63% in FY26, rising to nearly ₹1.5 lakh by March 31, 2026, driven by global safe-haven demand amid geopolitical tensions. Equities disappointed investors with the BSE Sensex declining about 5% in FY26. Volatility intensified toward the end of the year as the Sensex fell nearly 15% in the fourth quarter. This prompted investors to divert funds to gold ETFs, which recorded net inflows of 31,561 crore in the March quarter, the highest quarterly inflow of the year.
According to Vikram Dhawan, commodities head and fund manager, Nippon India Mutual Fund, investment demand and jewellery demand in gold have long moved in opposite directions during price spikes.

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Union Pacific: 2 Key Dates Are Coming (Earnings Preview)

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Union Pacific: 2 Key Dates Are Coming (Earnings Preview)

Union Pacific: 2 Key Dates Are Coming (Earnings Preview)

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USA Rare Earth Stock Surges 8% on $2.8 Billion Serra Verde Acquisition Creating Global Rare Earth Powerhouse

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FTSE 100 Surges 0.8% Today as Oil Eases and Markets

NEW YORK — Shares of USA Rare Earth Inc. climbed more than 8% in early Monday trading on April 20, 2026, rising $1.60 to $21.55 after the company announced a major $2.8 billion deal to acquire Serra Verde Group, a move that instantly expands its access to producing mines and all four key magnetic rare earth elements while strengthening its position in the global supply chain.

USA Rare Earth
USA Rare Earth Stock Surges 8% on $2.8 Billion Serra Verde Acquisition Creating Global Rare Earth Powerhouse

The acquisition, unveiled early Monday, positions USA Rare Earth as a formidable player aiming to challenge China’s dominance in rare earths. Serra Verde operates a mine in Brazil that currently produces all four magnetic rare earths — neodymium, praseodymium, dysprosium and terbium — essential for high-performance permanent magnets used in electric vehicles, wind turbines, defense systems and advanced electronics.

USA Rare Earth (NASDAQ: USAR) CEO Barbara Humpton described the transaction as transformative during a CNBC “Squawk Box” appearance. “This deal gives us immediate access to a producing mine with all four magnetic rare earths, accelerating our mine-to-magnet strategy and de-risking our supply chain,” she said.

The Serra Verde acquisition comes on the heels of several positive developments that have fueled investor enthusiasm. In recent weeks, the company completed first commercial yttrium metal production, appointed Chaitan Kansal as chief commercial officer, formed a strategic partnership in France through an investment in Carester, and advanced its Stillwater, Oklahoma magnet manufacturing facility.

Analysts reacted swiftly to the news. Wedbush initiated coverage with an “Outperform” rating, while other firms highlighted the deal’s potential to create one of the largest integrated rare earth platforms outside China. The stock’s surge reflected renewed confidence in USA Rare Earth’s ability to execute on its ambitious vertical integration plan, from mining at the Round Top deposit in Texas to magnet production.

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USA Rare Earth has aggressively built out its capabilities in recent months. It now holds 100% ownership of the Round Top project in West Texas after acquiring the remaining 18.6% stake from Texas Mineral Resources Corp. in March for approximately $73 million in stock. Round Top is considered one of the richest known U.S. deposits of heavy rare earth elements, gallium and beryllium, with commercial production targeted for late 2028 under an accelerated mining plan.

The company ended 2025 with $359.9 million in cash and no significant debt. Following a $1.5 billion PIPE financing that closed in late January 2026, its liquidity stood near $1.75 billion. Definitive documentation for an additional $1.6 billion in funding from the U.S. Department of Commerce under the CHIPS Program is expected to be finalized this month, subject to milestone achievements. This government support underscores Washington’s push to reduce reliance on Chinese-controlled supply chains for critical minerals.

The Serra Verde deal is expected to be funded through a combination of cash, stock and potentially new debt facilities, though specific terms were not fully detailed in the initial announcement. The transaction would provide USA Rare Earth with immediate production revenue and feedstock diversity, complementing its domestic assets and international processing partnerships in the UK and France.

Rare earths have gained heightened strategic importance amid U.S.-China tensions and the global transition to clean energy and advanced defense technologies. China controls roughly 94% of rare earth magnet production and an even higher share of heavy rare earth processing. USA Rare Earth’s integrated approach — mining, refining, metal production and magnet manufacturing — aims to create a secure Western alternative.

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The Stillwater facility commissioned its Phase 1A magnet production line earlier in 2026 and is on track for commercial output of sintered neodymium-iron-boron magnets. The company expects to scale capacity significantly, targeting over 10,000 metric tons of annual magnet production by the end of the decade. Recent milestones include successful yttrium metal output and ongoing hydrometallurgical demonstration work in Colorado.

Wall Street sentiment has turned increasingly bullish. Consensus price targets average around $29 to $30, with some analysts seeing potential for $35 or higher if execution milestones are met. The stock has shown strong year-to-date gains despite periodic volatility tied to broader market moves and sector-specific risks.

Critics note the high execution risk inherent in mining and materials projects. USA Rare Earth faces challenges including permitting timelines at Round Top, technical hurdles in scaling magnet production, potential cost overruns and competition from established players. Dilution from recent financings and acquisitions has also been a concern for some shareholders, though the influx of capital has strengthened the balance sheet.

The company’s leadership team has been bolstered with executives experienced in government relations, commercial strategy and international operations. CEO Humpton, formerly of Siemens, has emphasized disciplined capital deployment and partnerships with major manufacturers in automotive, defense and renewable energy sectors.

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Broader market context on Monday included mixed trading amid ongoing Middle East tensions that have lifted commodity prices. Rare earth stocks have benefited from renewed focus on supply security, with USA Rare Earth standing out due to its combination of domestic assets, government backing and now expanded international production access.

For investors, the Serra Verde acquisition represents a step change. Instead of relying solely on future development at Round Top, USA Rare Earth gains near-term cash flow and operational expertise from a producing asset. The deal also diversifies geographic risk while maintaining focus on high-value magnetic rare earths critical for national security and economic competitiveness.

Looking ahead, key catalysts include finalization of the $1.6 billion Commerce Department funding in April, progress updates on the Stillwater plant, and further details on the Serra Verde integration. First-quarter 2026 results and any supply agreements with major customers could provide additional momentum.

USA Rare Earth’s market capitalization has grown substantially as it transitions from a development-stage company to an emerging producer. The stock’s recent performance reflects growing recognition that reshoring critical mineral supply chains is a multi-year priority with bipartisan support in Washington.

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While risks remain — including regulatory delays, commodity price fluctuations and geopolitical factors — the combination of strong funding, operational milestones and the Serra Verde transaction has investors betting on USA Rare Earth’s ability to capture a meaningful share of the global rare earth market.

As trading continued Monday morning, the 8%+ gain held with elevated volume, signaling broad participation from both institutional and retail investors. The move extended recent positive momentum following yttrium production news and the chief commercial officer appointment last week.

USA Rare Earth’s story is part of a larger U.S. effort to build resilient supply chains for technologies of the future. With Serra Verde now in the fold, the company moves closer to its goal of becoming a global champion in rare earth elements, oxides, metals and magnets — delivering materials essential for innovation and security while creating long-term shareholder value.

Whether the latest surge proves sustainable will depend on continued execution. For now, the market appears to be rewarding USA Rare Earth’s bold expansion strategy in a sector where geopolitics and national priorities increasingly drive investment decisions.

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Petrol thefts surge as Iran war pushes up fuel costs

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Petrol thefts surge as Iran war pushes up fuel costs

One petrol retailer says he is experiencing about five drive-offs a week at each forecourt, costing him thousands.

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Kohl's: As Long As The Demand Is Weak I Would Give It A Pass

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Kohl's: As Long As The Demand Is Weak I Would Give It A Pass

Kohl's: As Long As The Demand Is Weak I Would Give It A Pass

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2027 Launch Still Possible Despite RAM Shortage and Delay Fears

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Facebook's new rebrand logo Meta is seen on smartpone in front of displayed logo of Facebook, Messenger, Intagram, Whatsapp, Oculus in this illustration picture taken October 28, 2021.

LOS ANGELES — As the PlayStation 5 continues its strong sales run and the PS5 Pro pushes high-end performance, speculation about Sony’s next-generation console, the PlayStation 6, is intensifying in April 2026, with insiders divided over whether the PS6 will arrive in late 2027 or slip to 2028 or even 2029 due to a global memory chip shortage driven by artificial intelligence demand.

Sony has not officially confirmed development of the PlayStation 6, but leaks and analyst reports suggest the company is deep into planning for a console that could feature dramatic leaps in power, AI-driven graphics and possibly a trio of models including a dedicated handheld. PlayStation lead architect Mark Cerny hinted at the timeline in an October 2025 video with AMD, describing advanced machine-learning technologies as “still very early days” but expressing excitement about bringing them to “a future console in a few years’ time.”

That comment has fueled debate. While some leakers maintain a holiday 2027 target, recent reports from Bloomberg and analysts like David Gibson of MST International point to potential delays. The ongoing DRAM shortage, exacerbated by AI data centers competing for memory chips, has raised production costs and forced Sony to consider extending the PS5 lifecycle longer than previous generations.

Prediction markets reflect the uncertainty. On Kalshi, as of early April 2026, only about 25% of bettors believed the PS6 would be announced before 2027, with the majority expecting a later reveal. Despite the skepticism, several well-known insiders continue to push for a 2027 window. YouTuber Moore’s Law Is Dead has reiterated that internal documents show manufacturing readiness in Q2 2027, aligning with a late 2027 or early 2028 launch. AMD insider KeplerL2 has echoed similar timelines on forums, claiming the chipset is nearly complete.

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The rumored hardware specifications paint an ambitious picture. The PS6 is expected to use a custom AMD chip based on Zen 6 CPU architecture paired with an RDNA 5 GPU. Performance estimates range from 34 to 40 teraflops or more — roughly triple the rendering power of the base PS5. Leaks suggest up to 30GB or even 32GB of GDDR7 memory with significantly higher bandwidth, potentially enabling native 4K at 120 frames per second or advanced ray tracing and path tracing without heavy reliance on upscaling.

AI is set to play a central role. Successors to the PlayStation Spectral Super Resolution (PSSR) technology could include hardware-level neural arrays for frame generation, upscaling and even in-game assistance. Cerny has emphasized that the biggest generational jump may come from ray tracing and AI enhancements rather than raw horsepower alone. Full backward compatibility with both PS4 and PS5 games is widely expected, a feature that would help ease the transition for the massive existing user base.

Pricing remains a hot topic amid inflation and component costs. Some leaks suggest a base model could launch around $499 to $599, similar to the PS5, while a more powerful variant or “Pro” edition might approach $749 or higher. A budget “Lite” or digital-only version could start as low as $350 to $400. One recent report from Moore’s Law Is Dead claimed the standard PS6 might land at a relatively reasonable $749, though rising memory prices could push that figure upward if delays occur.

Adding to the excitement — and complexity — are rumors that Sony plans to launch not one but three PlayStation 6 devices. Alongside the main console, insiders point to a slimmer or Lite variant and a dedicated native handheld, codenamed “Project Canis.” This handheld would reportedly offer full backward compatibility with PS4 and PS5 titles, running them natively rather than through streaming, and could compete directly with Nintendo’s Switch and other portable devices. Leaks suggest it would launch alongside the primary PS6 models, potentially in 2027 or 2028.

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The multi-model approach would mirror strategies seen with the PS5 lineup but expand into the handheld space, where Sony has not competed directly since the ill-fated PlayStation Vita. A powerful portable PlayStation could unify the ecosystem, allowing players to continue console games on the go with minimal compromises.

Development appears well underway despite the silence from Sony. Reports indicate dev kits could surface later in 2026, giving third-party studios time to prepare next-generation titles. The focus on AI and efficiency is expected to help mitigate some power and thermal challenges, with Sony aiming for a more compact design than the current PS5.

The RAM shortage remains the biggest wildcard. AI-driven demand has tightened supply chains, increasing costs for GDDR7 and other high-bandwidth memory. Sony benefited from earlier inventory for the PS5, but scaling production for a new console could prove costly. Some analysts argue that delaying to 2028 or 2029 would allow component prices to stabilize and give the PS5 more runway, especially with the Pro model still relatively new.

Sony’s strategy with the PS5 has already broken from the traditional seven-year cycle by releasing a mid-generation upgrade. Extending that approach could maximize profits from the current generation while the company refines PS6 technology. However, prolonged waits risk losing momentum to competitors, including Microsoft’s next Xbox, rumored under the codename Project Helix with its own 2027 or 2028 ambitions.

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Gamers are already voicing opinions online. Forums and social media show divided camps: some urge Sony to stick to 2027 to maintain momentum, while others prefer waiting for mature hardware that justifies a premium price. The prospect of a handheld has generated particular enthusiasm, with many hoping it could revive portable PlayStation gaming in a meaningful way.

Backward compatibility would be a major selling point. Full support for PS4 and PS5 libraries would ensure millions of existing games remain playable, reducing the “library reset” feeling that has accompanied past generational shifts. Enhanced features, such as AI upscaling for older titles, could make legacy games look and perform better on the new hardware.

As with any unannounced product, all details remain speculative. Sony typically reveals next-generation consoles with a polished event, showcasing hardware and key first-party titles. No official announcement window has been shared, and the company continues to focus on PS5 software support, including major exclusives still in development.

The PlayStation 6 rumors underscore the challenges facing the console industry in an era of skyrocketing component costs and rapid technological change. AI is no longer just a buzzword for graphics — it is becoming central to rendering, gameplay systems and even development tools. Sony’s emphasis on machine learning, as hinted by Cerny, suggests the PS6 could deliver experiences that feel truly next-generation rather than incremental.

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Whether the console lands in 2027, 2028 or later, expectations are high. Fans hope for significant jumps in visual fidelity, faster load times, more immersive audio and innovative features that leverage the rumored hardware. The inclusion of a handheld could expand the audience dramatically, bringing console-quality gaming to new scenarios.

For now, the PlayStation community must wait for concrete news. In the meantime, the PS5 and PS5 Pro continue to receive strong support, with a robust lineup of games keeping players engaged. Sony has a history of delivering polished hardware when it finally unveils a new console, and the PlayStation 6 appears poised to continue that tradition — whenever it ultimately arrives.

Industry watchers will monitor supply chain updates, AMD partnership developments and any subtle comments from executives for further clues. Until then, the PS6 remains one of gaming’s most anticipated mysteries, with rumors suggesting it could redefine what a home console can do in an increasingly AI-powered world.

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Zions Bancorporation: Solid Q1 Results (NASDAQ:ZION)

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Zions Bancorporation: Solid Q1 Results (NASDAQ:ZION)

This article was written by

The Pioneer Of Seeking Alpha’s BAD BEAT Investing, Quad 7 Capital is a team of 7 analysts with a wide range of experience sharing investment opportunities for nearly 12 years. They are best known for their February 2020 call to sell everything & go short, & have been on average 95% long 5% short since May 2020. The broader company has expertise in business, policy, economics, mathematics, game theory, & the sciences. They share both long & short trades & invest personally in equities they discuss within their investing group BAD BEAT Investing, focused on short- & medium-term investments, income generation, special-situations, & momentum trades. Rather than just give you trades, they focus on teaching investors to become proficient traders through their playbook. Their goal is to save you time by providing in depth, high-quality research, with crystal clear entry and exit targets. They have a proven track record of success.Benefits of BAD BEAT Investing include: Learning how to understand the pinball nature of markets, executing well-researched written trade ideas each week, use of 4 chat rooms, receive daily complimentary key analyst upgrade/downgrade summaries, learning basic options trading, & extensive trading tools. If you would like to learn more, click the link above!

Analyst’s Disclosure: I/we have no stock, option or similar derivative position in any of the companies mentioned, and no plans to initiate any such positions within the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

Seeking Alpha’s Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

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KalVista CCO Nicole Sweeny sells $37,642 in company stock

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KalVista CCO Nicole Sweeny sells $37,642 in company stock

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