According to a filing with the exchange, the company said it signed a partnership agreement with Bahiafarma and Bionovis for Pertuzumab in Brazil, marking an important milestone in advancing production and commercialisation of the HER2-positive breast cancer therapy under the country’s Productive Development Partnership (PDP) program.

The company further said that the consortium of Biocon, Bahiafarma and Bionovis received 100% allocation under Brazil’s 10-year PDP program for Pertuzumab.

Also Read | Biocon signs 10-year Brazil supply deal for Pertuzumab breast cancer drug

Pertuzumab is a monoclonal antibody used in the treatment of HER2-positive breast cancer, and at present, the product is not manufactured locally in Brazil and is a significant expenditure for the country’s Unified Health System (SUS).

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The productive development partnership provides the consortium exclusive access to Brazil’s public healthcare market, which accounts for approximately 70% of the country’s demand for Pertuzumab.
This partnership also supports the long-term adoption of Biocon’s product within Brazil’s public oncology network.“Brazil is an important country for Biocon, and our journey here reflects the transformative potential of strong partnerships in building local capabilities and expanding access to high-quality, affordable medicines. This long-term supply contract for Pertuzumab marks a significant milestone in this journey, enabling us to reach more patients living with HER2-positive breast cancer and address an important healthcare need at scale,” said Shreehas Tambe, CEO & Managing Director, Biocon.

“In partnership with Bahiafarma and Bionovis, we are bringing together science, innovation, manufacturing excellence and local expertise to create a more sustainable pathway for access to this important cancer therapy. Together, we are not only supporting better patient outcomes but also helping build a stronger, more resilient healthcare ecosystem in Brazil,” Tambe further said.

The global biopharmaceutical company further said that it will receive milestone payments and a share of revenues generated from the Brazil PDP opportunity over a 10-year period. As part of the PDP framework, the product will undergo phased localisation in Brazil in the mid to long term.

Bahiafarma and Bionovis

Bahiafarma is a public pharmaceutical laboratory of the State of Bahia, Brazil, focused on pharmaceutical research, technological development, innovation and the production and supply of medicines and other health products, particularly for Brazil’s SUS.

“We celebrate the conclusion of this stage with the certainty that we are advancing in a strategic project for public health. It is the result of a work built in partnership, and that paves the way for the incorporation of a highly complex technology, contributing to Brazil strengthening its capacity to produce essential medicines for its Unified Health System (SUS),” said Ceuci Nunes, CEO, Bahiafarma.

Bionovis is a Brazilian biotechnology company focused on developing, manufacturing and commercialising complex biological medicines and biosimilars, with a strong emphasis on technology transfer, local biopharmaceutical manufacturing and expanding access to advanced therapies in Brazil.

Also Read | Biocon arm gets Japan nod for cancer drug pegfilgrastim biosimilar

“Through our partnerships with Biocon and Bahiafarma, we reinforce our commitment to the public policies of the Health Economic-Industrial Complex and to Productive Development Partnerships, expanding the Brazilian population’s access to highly complex biological medicines, generating incomes, employing specialised professionals, and promoting the country’s productive autonomy,” said Odnir Finotti, CEO, Bionovis.

In 2026 so far, Biocon shares were up 1.84% and nearly 8.44% in the last one year. The stock gained 48.24% in the last three years and 11% in the last five years.

(Disclaimer: Recommendations, suggestions, views and opinions given by the experts are their own. These do not represent the views of The Economic Times.)

Telegram users began reporting widespread access problems late Monday night, with outage-tracking site Downdetector logging a sharp surge in complaints starting around 10:46 p.m. EDT, growing into one of the more significant reported disruptions to affect the messaging platform in recent months.

Downdetector’s official account flagged the surge in a post shortly after the reports began, asking affected users how the disruption was impacting them and directing people to its live outage map for updates. The hashtag “TelegramDown” quickly began circulating on social media as users compared notes on the issue, with the post drawing more than 11,000 views within a short window of being published.

Independent monitoring service Technobezz tracked the disruption climbing steadily overnight, reporting 26 outage reports in the 24 hours leading up to 2:50 a.m. UTC Tuesday, with the vast majority of complaints, 81%, centered on connection issues. Reports spanned six distinct global regions, according to the tracker, with core-feature failures and slow loading or buffering rounding out the remaining reported problems.

Separate real-time monitoring service Instatus characterized Telegram as “currently down” as of its most recent check, logging 57 recent outage reports as part of its ongoing 12-hour tracking window for the platform.

Not every monitoring service reached the same conclusion about the scope of the disruption. StatusGator reported Telegram as “currently operational” as of its own assessment, while still logging 13 user-submitted outage reports over the preceding 24-hour period. Similarly, UptimeRobot’s most recent automated check, run early Tuesday morning from North America, did not detect any unusual response times or error codes affecting the platform, illustrating the kind of inconsistency that can emerge across different outage-tracking services depending on their specific monitoring locations, methodologies and report thresholds.

Telegram, the widely used messaging app founded by Pavel Durov, has built a global user base exceeding 200 million monthly active users in recent years, offering encrypted messaging, large group channels and cloud-based chat storage as key differentiators from competing platforms. The app has faced periodic government restrictions in several countries, including Russia, Iran and China, tied to disputes over encryption keys and user data requests, though Monday’s reported disruption did not appear connected to any specific regional censorship action based on the available reporting.

Telegram has experienced a documented pattern of intermittent outages over the past several months, according to StatusGator’s incident history for the platform. Recorded incidents include an app-and-website outage lasting 3 hours and 23 minutes detected Aug. 13, a shorter connectivity disruption lasting 1 hour and 11 minutes detected Aug. 12, and a brief service outage lasting 18 minutes detected June 29. None of those prior incidents were officially acknowledged by Telegram at the time they were logged, according to StatusGator’s tracking, a pattern that has continued with Monday’s reported disruption as well.

Given Telegram’s scale and its function as a primary communication tool for millions of users worldwide, including in regions where the app serves as a critical channel for news distribution and organizing, outages affecting the platform tend to draw significant and immediate public attention. Users experiencing connectivity problems frequently turn to alternative platforms like X to check whether an outage they are experiencing reflects a broader, shared disruption or is instead isolated to their own device, network or geographic region.

Outage-tracking platforms including Downdetector, StatusGator and Instatus compile crowdsourced user reports and cross-reference them against automated server checks to help determine whether a genuine, widespread service disruption is underway, as opposed to isolated technical issues affecting only a subset of users. A sudden, sharp spike in reports spanning multiple regions simultaneously, as occurred late Monday, is generally treated as a stronger signal of a broader platform-level issue rather than a series of unrelated, localized problems.

As of the most recent updates, Telegram had not issued a detailed public statement addressing the specific cause of Monday night’s reported disruption. The company’s official status communications, when issued during past incidents, have historically come through Telegram’s own social media channels or its dedicated status page, though the company’s public acknowledgment of outages has at times lagged behind the volume of user reports being tracked independently by third-party monitoring services.

For users experiencing ongoing access issues, standard troubleshooting guidance typically recommended by technology support resources includes attempting to access Telegram from an alternative browser, device or network, such as a mobile hotspot, disabling any active VPN connection, clearing the device’s DNS cache, and restarting the home router before assuming a broader Telegram-wide outage is responsible for the disruption. If the platform loads successfully from a different network or device, the underlying problem is more likely tied to a user’s own local internet connection rather than reflecting a genuine issue with Telegram’s servers.

As of early Tuesday morning, it remained unclear how long the reported disruption would persist or what specific technical cause might be responsible for the connectivity issues affecting users across multiple regions. Given the conflicting readings from different monitoring services, with some characterizing the platform as fully down and others describing it as operational despite continued user complaints, the true scope and severity of Monday night’s disruption remained somewhat uncertain even as reports continued accumulating into the early morning hours.

Affected users were advised to continue monitoring both Downdetector’s live outage tracker and independent status services including Instatus and StatusGator for updates, as well as Telegram’s own official channels, while the company worked, without formal public acknowledgment as of the time of this report, to address whatever underlying issues were contributing to the reported connectivity problems affecting the platform late Monday and into early Tuesday.

MELBOURNE, Australia — Western Bulldogs veteran Tom Liberatore has announced his retirement from AFL football after 268 games with the club, bringing an end to a 16-year career defined by hard-nosed midfield play, a premiership medal and a deep, generational connection to the western Melbourne suburbs the club calls home.

Liberatore, 34, informed his teammates of the decision following the Bulldogs’ elimination-final loss to Adelaide on Saturday night, a match that marked his final appearance for the club. His 2026 season had been severely limited to just 11 senior games, as a string of concussions and knee injuries continued to take a physical toll on the veteran midfielder.

A father-son recruit selected with pick 40 in the 2010 national draft, Liberatore followed in the footsteps of his father, Tony Liberatore, a Bulldogs great in his own right who played 283 games for the club. Tom went on to become one of only 15 players in Bulldogs history to reach 250 games, and last year was named among the 25 Greatest Bulldogs to ever wear the club’s red, white and blue.

“This Club and its community have been such a huge part of my life,” Liberatore said in a statement. “I’m so fortunate to have lived out my dream for 16 years, from watching my old man play for the club to being part of a premiership that meant so much to all of our fans and to the western suburbs, it’s been a real privilege.”

Liberatore reflected on his decision to step away from playing while remaining connected to the club in a different capacity.

“I still love being here and competing each week but it’s time for me to step aside, spend more time with my family and friends and support this great club from the stands,” Liberatore said. “I’ve built lifelong friendships with many teammates through the years, that’s what means the most to me.”

He closed his statement by thanking the club’s players, coaches, staff and supporters for their role throughout his career.

“I want to take the opportunity to thank everyone at the club: players, coaches and staff for the amount of effort and time they’ve dedicated to me over the years,” Liberatore said. “I also want to thank the members and fans who have been incredible during my time here and supported me through all of the ups and downs. I’m really proud of where the club is going and excited about what the group is capable of moving forward. I’m looking forward to watching on with a beer in hand.”

Liberatore’s on-field career included several significant individual and team honors. He won the club’s Charles Sutton Medal, awarded to the Bulldogs’ best and fairest player, in 2014, narrowly defeating teammate Jack Macrae in a breakout season. He finished in the top three of the club’s best and fairest voting on five additional occasions and was a key figure in Western Bulldogs’ drought-breaking 2016 premiership triumph, playing 21 games that season, including a standout performance in the finals series in which he recorded 19 tackles in a single match. Liberatore twice returned from ruptured ACL injuries during his career, a testament to the resilience that came to define his reputation among teammates and supporters alike.

Statistically, Liberatore finishes his career having played 267 to 268 games, depending on the specific source, kicking 93 goals over that span, according to figures compiled following his retirement announcement. He also polled a total of 50 Brownlow Medal votes across his career and was named the Bulldogs’ vice-captain in 2024, reflecting his standing as a senior leadership figure within the club’s playing group in his later seasons.

Bulldogs coach Luke Beveridge, who coached Liberatore for 12 seasons including the 2016 premiership campaign, offered an emotional tribute to the retiring midfielder.

“Tom has been the spiritual catalyst within our playing ranks for such a long period of time,” Beveridge said. “Through the challenges he has faced, he has had a fierce will and desire to claw his way back. ‘Libba’ has always set about influencing everyone he comes in contact with in his own unique, caring and quirky characteristic way. Always a fierce competitor, he has been inspirational with his tenacity and confrontational brand ensuring his teammates always walk a little taller and feel a little more self-assured. I am extremely grateful to have coached Tom and I know all of our people see it as a great privilege to have shared Tom’s AFL football experience with him.”

Beyond his contributions on the field, Liberatore built a significant profile within the Bulldogs’ community work over the course of his career. He served as a longtime ambassador, advocate and volunteer with the Western Bulldogs Community Foundation, dedicating time to mentoring youth, supporting local educational programs, and working to address homelessness across Melbourne’s western suburbs. Most recently, Liberatore partnered with the Salvation Army to help launch the Lighthouse Café, an initiative providing hot meals and a safe space for community members in need, work that earned him a second consecutive nomination for the AFL’s Jim Stynes Community Leadership Award.

With Liberatore’s retirement, Bulldogs captain Marcus Bontempelli becomes the only remaining player on the club’s list who was part of the 2016 premiership-winning squad, a marker of just how significantly the club’s playing group has turned over in the decade since that historic flag. Tom and Tony Liberatore also remain just the second father-son pairing in AFL history to each play 250 or more games for the same club, joining Essendon’s Ken and Dustin Fletcher in that distinction.

As the Bulldogs move forward without one of the most beloved and recognizable figures in the club’s recent history, Liberatore’s retirement closes out a career that blended on-field toughness with an off-field commitment to community work that supporters and club officials alike have described as central to his legacy at the Kennel.

This article was written by

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NEW YORK — Sandisk shares jumped again as investors treated a former flash-drive name like an artificial-intelligence infrastructure stock, leaving a simple question after a violent rally: whether the tape still offers a buy, or only a bet that memory prices stay scarce.

Sandisk closed Sept. 4 at $1,740, up $185.01, or 11.90%, from the prior session. Overnight trading printed about $1,767. The session’s range ran from $1,581 to $1,740. The 52-week span, from about $68 to more than $2,350, shows how fast the story changed after the company was spun out of Western Digital in early 2025.

The move follows fiscal fourth-quarter results for the period ended July 3. Revenue was $8.97 billion, up 51% from the prior quarter and 372% from a year earlier. Data-center sales were $2.98 billion, about a third of the quarter and more than double the prior period. A year earlier that line was about $213 million. Non-GAAP gross margin reached 84.6%, compared with 26.2% a year earlier. Adjusted earnings were reported well above year-ago losses. Management said about two-thirds of the sequential revenue increase came from higher prices and one-third from more bits shipped.

Guidance kept the heat on. For fiscal first-quarter 2027, Sandisk forecast revenue of $10.3 billion to $10.80 billion and non-GAAP profit of $44 to $46 a share, with gross margin 83% to 85%. Reuters noted the revenue midpoint sat above one consensus set even as the stock sold off after the print when other estimate services had wanted more.

Chief Executive David Goeckeler has framed the boom as structural, not seasonal. “AI is fundamentally a memory-centric storage-intensive problem,” he said on the August earnings call. At the company’s investor day he said, “Our strong performance today is the direct result of disciplined execution against the strategy we outlined 18 months ago.” He has also said Sandisk grows supply “primarily through nodal transitions rather than wafer additions.”

That last point is why bulls call the stock a buy on a pullback and why skeptics wait. Memory cycles have historically ended when suppliers add wafers and prices collapse. Sandisk is arguing it can lift bits in the mid-to-high teens by moving to denser technology such as BiCS8 without a classic capacity binge. Capital spending is described as modest relative to sales. The long-term model for fiscal 2028 through 2030 targets mid-to-high-teens revenue growth, about 80% non-GAAP gross margin, about 75% operating margin and adjusted free cash flow near 50% of revenue. Those figures are below the 84.6% gross margin just printed, which is management’s way of telling the market the peak print may not be the mid-cycle print.

Contracts are the other half of the bull case. Chief Financial Officer Luis Visoso said Sandisk had 10 multiyear “new business model” agreements with eight customers, five signed since April, running as long as five years with a weighted average duration of more than four years. “The total expected revenue from all our NBMs we have signed is a minimum of $93.9 billion, assuming floor pricing,” Visoso said. Management has said the deals should cover about half of bits in fiscal 2027 and about two-thirds in fiscal 2028, backed by customer deposits and other financial support. That is closer to a contracted industrial book than to the spot NAND market Sandisk used to live in.

The company also authorized large buybacks as cash piled up. It repaid remaining term-loan debt, moved to a net cash position and later expanded repurchase authority into the tens of billions. Full-year free cash flow swung from an outflow in fiscal 2025 to more than $11 billion in fiscal 2026 on company figures. S&P Global Ratings raised Sandisk to BB+ with a positive outlook after the deleveraging, citing constrained NAND supply through fiscal 2027 in its base case.

None of that answers “buy now” as a binary. At $1,740 the stock is no longer the neglected spinoff that traded in the double digits. It has already discounted a multiyear AI storage cycle. Trailing earnings multiples compressed as profits exploded; forward estimates imply a lower multiple if guidance holds. That can look cheap if $10 billion-plus quarters continue. It looks expensive if NAND prices normalize the way they have after every prior shortage.

The risks are familiar. Edge products — phones, PCs, cards — still supply more than half of quarterly revenue even as data center grows faster. Consumer units can drop just as data-center contracts lock in. Competitors in NAND and SSDs can still add supply. Customer concentration in a handful of AI builders means a pause in GPU cluster builds would hit Sandisk with a lag, not instantly, but it would hit. Gross margins in the mid-80s have little room to surprise to the upside and a long way to fall if floor prices in the new contracts sit well below spot.

Goeckeler has said customers returned after a single quarter asking to raise three-to-five-year demand. He estimated the NAND market would exceed $300 billion in calendar 2026, triple the prior year, and approach $500 billion in 2027, with data center taking a larger share of the total. Those are company forecasts, not booked sales.

For a newsroom ledger, the buy case is this: constrained bits, contracted floors, high cash conversion, and a CEO who says the shortage is an AI architecture problem rather than a one-year restock. The hold-or-wait case is this: the stock already ran from spinoff leftovers to a triple-digit handle, August’s 29% bounce recovered a prior slide, and Sept. 4’s 12% pop prices in another quarter of $10 billion sales before that quarter is delivered.

Sandisk is no longer asking investors to believe flash cards will matter. It is asking them to believe memory stays scarce long enough for $94 billion of minimum contract value to turn into cash at margins the old Sandisk never earned. Whether that is a buy at $1,740 depends less on the closing print than on whether the next shortage ends on schedule — or, this time, does not.

HFCL shares remained locked in the 5% upper circuit at Rs 255.16 apiece on NSE. The stock has rallied more than 267% in 2026 so far, even as the broader Nifty 500 index has dropped 3%. The shares of the company have jumped 7% in one week and 22% in a month.

Sterlite Tech’s returns are even more impressive, as the stock has delivered a whopping 705% return in 2026 so far. The stock which remained locked in the 5% upper circuit at Rs 825.60 apiece on NSE on Tuesday morning, has jumped over 29% in a month and 19% in a week.

Also read | HFCL’s FY26 order book surges 113% to Rs 21,206 crore

Why are HFCL shares rallying?

HFCL on Saturday released its annual report for FY26, reporting a sharp expansion in its order book and strong financial performance. The company’s FY26 order book stood at Rs 21,206 crore, marking a sharp 113% year-on-year increase and signalling robust business momentum across its key segments.

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The annual report also highlighted strong growth across HFCL’s financials. Its revenue from operations increased nearly 22% year-on-year to Rs 4,949 crore, while EBITDA surged more than 63% YoY to Rs 827 crore. Profit after tax sharply surged more than 90% YoY to Rs 329 crore, while earnings per share (EPS) rose 73% YoY to Rs 2.13, reflecting the company’s improved profitability during the year.
HFCL shares have hit the 5% upper circuit for the third consecutive session today. The company has a market capitalisation of around Rs 38,695 crore.

Why are Sterlite Tech shares rallying?

Sterlite Technologies last week outlined its long-term growth plans, including a target of becoming one of the top five players globally in optical connectivity solutions and achieving revenue of Rs 20,000 crore by FY29.

Also read | Sterlite Tech targets Rs 20,000 crore revenue by FY29 amid booming AI demand

The company identified optical TAM expansion, customer co-development, integrated connectivity solutions and tech-led differentiation as key growth drivers. It also plans to expand its capacity to 1.5 times to support the next phase of growth.

The company has also approved a Rs 3,000 crore capital expenditure plan to expand capacity at its existing manufacturing facility. The proposed expansion will increase its existing installed manufacturing capacity by approximately 50%, with the additional capacity expected to be operational by the end of FY29.

Sterlite Tech shares have also hit the 5% upper circuit for the third consecutive session today. The company has a market capitalisation of more than Rs 42,428 crore.

Disclosure: “This article has been written by Debaroti Adhikary, who is not a SEBI-registered Research Analyst or an Investment Adviser. Debaroti Adhikary and her ‘relative(s)’ (as defined under Section 2(77) of the Companies Act, 2013) do not hold any financial interest in the companies mentioned in this article as of the date of publication. The views/recommendations mentioned in this article, wherever applicable, are those of the respective SEBI-registered Research Analyst/brokerage and have been reproduced/reported with due attribution. They should not be construed as the views or recommendations of The EconomicTimes Digital or the journalist. Readers are advised to consider the original research report and make their investment decisions based on their own assessment.”

TUCSON, Ariz. — More than seven months after Nancy Guthrie disappeared from her Arizona home, a retired FBI agent is theorizing that the 84-year-old mother of “Today” co-anchor Savannah Guthrie was taken in a kidnapping-for-ransom scheme that spiraled out of the captors’ control, potentially ending in her death from a medical emergency shortly after she was seized.

Frank Storey, a retired FBI agent, laid out the theory during an appearance on the YouTube channel of fellow former FBI officer Jennifer Coffindaffer. Storey said he believes Guthrie was abducted as part of a ransom plot, but that something unexpected happened after the abduction that the captors had not anticipated. He suggested Guthrie may have experienced a medical emergency that ultimately led to her death, though he was careful to characterize the theory as speculation rather than a confirmed finding.

Guthrie has remained missing since vanishing from her Catalina Foothills home near Tucson in the early hours of Feb. 1, 2026. Investigators have continued searching for her from multiple angles, including the working theory that she was kidnapped, though no suspect has been publicly identified or arrested seven months into the case.

The prolonged lack of an arrest, combined with the sheriff’s department’s limited public updates, has led some observers and critics to question whether the investigation has effectively gone cold. Scott Augenbaum, another retired FBI agent, has pushed back firmly against that characterization in comments to Tucson television station KOLD.

“This is by no means a cold case,” Augenbaum said. “A cold case is something that has been closed; it’s been put away. So in my opinion, this case is not closed at all. It’s still being held very tightly guarded by law enforcement, which I would expect at this point in time.”

Augenbaum said the absence of regular public announcements from investigators should not be interpreted as a sign that law enforcement has abandoned the case. Drawing on his own experience working investigations during his time with the bureau, he described two very different scenarios that could explain a prolonged period without an arrest.

“There were cases where we didn’t really have any leads or anything like that, and we just played that close,” Augenbaum said. He added that other investigations unfold quite differently: “There were situations where we kind of had a really amazing idea. We knew who did it, but we had to build the case against that person.”

Augenbaum said Guthrie’s case could realistically fall anywhere between those two possibilities, or somewhere in between, given the limited information investigators have made public so far.

Guthrie’s disappearance has drawn sustained national attention throughout the year, driven in significant part by her daughter’s prominent role as a co-anchor on NBC’s “Today” show. Guthrie was last seen at her home on the evening of Jan. 31, 2026, after being dropped off by family members, and was reported missing the following morning after failing to arrive for a scheduled church service with friends.

Investigators have pursued a range of leads over the course of the investigation, including doorbell camera footage showing a masked, armed individual near Guthrie’s home around the time of her disappearance, along with two ransom notes the Pima County Sheriff’s Department later released publicly in an effort to generate additional tips. Forensic evidence recovered from the scene, including DNA samples and hair evidence, has so far failed to produce a confirmed match to any suspect, according to prior statements from investigators.

Despite the absence of a named suspect, Pima County Sheriff Chris Nanos has repeatedly reiterated that the investigation remains active, characterizing ongoing forensic analysis and continued review of incoming tips as evidence the case continues to move forward even without regular public updates.

Storey’s latest theory adds to a growing list of competing explanations that have circulated publicly throughout the investigation, none of which have been confirmed by law enforcement. Various retired agents and commentators have offered their own readings of the limited evidence made public so far, reflecting the intense ongoing interest in a case that has remained unresolved despite extensive media coverage and a substantial reward for information leading to Guthrie’s recovery.

As the investigation moves further past the seven-month mark, authorities have continued declining to provide detailed public updates on specific leads or the current status of forensic testing, a practice Augenbaum and other former investigators have said is consistent with standard law enforcement procedure in an active case involving a potential ongoing criminal investigation. For now, the Pima County Sheriff’s Department has indicated it will continue withholding a formal press conference on the case until investigators have a significant development to share, leaving both Guthrie’s family and the broader public following the case to continue awaiting answers about what ultimately happened to her.