The change of use proposal for the vacant retail unit in the High Street was recommended for approval by a Redcar and Cleveland Council planning officer, but turned down by members of the local authority’s regulatory committee.
Applicant Raman Amiri’s bid to create a shawarma-related venture on the site of the former Jubilee’s card shop belonging to late businessman Kenny Surtees attracted 123 objections from residents, with ward and neighbouring councillors also unhappy at the plans.
Mr Amiri did not appear before a meeting of the committee in support of his application and to answer questions, while members expressed doubts about whether there was sufficient space in the end terraced property to house a fully-fledged restaurant.
Advertisement
What the report said
The officer’s report said: “The premises was previously operated as a card shop which fell within the E use class.
“The use of the premises solely as a restaurant would not require consent as a restaurant also falls within the E use class.
“The proposal seeks to change the use of the premises to be a mix of restaurant (use class E) and hot food takeaway (use class sui generis) which would suggest that the takeaway element would not be ancillary to the main use as a restaurant.”
Residents complained about an over-concentration of fast food takeaways in the area – the proportion of which would further exceed the five per cent threshold of commercial units in hot food takeaway use as per council policy – a potential increase in food waste and litter, and illegal parking, along with a desire to see more independent/general shops.
Advertisement
Normanby ward councillor Curt Pugh said: “Normanby High Street already has more than enough takeaways.
“Residents repeatedly tell me they want a wider mix of shops and services, and the council itself has recognised the need to limit the number of hot food outlets.”
He added: “There are also serious concerns about the impact on nearby residents.
“Cooking smells, extractor fans, late-night customers, and delivery traffic will affect the flats above and the houses close by.”
Advertisement
Public Health South Tees was another objector.
The council planning officer’s view was that, as the new venture was not proposed to be open beyond 7pm each day and not late into the evening like most other hot food takeaways, this along with the mixed use aspect, meant that on balance the principle of a change of use was acceptable and it would also bring a vacant unit back into use.
Plans don’t ‘add up’
Eston councillor Stephen Martin said: “We need more diverse high streets and just filling them with fast food outlets isn’t acceptable.
“Our residents deserve better and the health of our community should be a high priority.”
Advertisement
Cllr Martin said the plans included no real seating area, in the sense of people sat at tables, with benches and stools instead.
He said the application did not “add up” in terms of space for restaurant seating as it was a “very small space”.
Cllr Martin said: “Is it a restaurant or is it just somewhere where you quickly sit down and wait for your food to come?”
He also said Normanby’s proportion of takeaways set against the overall number of available commercial units was more than eight per cent.
Advertisement
Cllr Martin also said while the proposed opening hours were 9am to 7pm, he questioned “who was going to be buying a shawarma at 9 o’clock in the morning?”
He said: “In three months time the applicant may have sought to apply for different timescales, for instance it may not open to 1pm or 2pm and then go onto midnight.
“Then we’d be in the same situation as everywhere else where lots of shops are closed during the day and then open up at night.”
The Greater Cambridge Partnership (GCP) says the works on Station Road near Shepreth railway station will provide safer crossings and improved routes for walking, wheeling and cycling
The Greater Cambridge Partnership (GCP) confirmed that Station Road will be shut at the Shepreth level crossing. Motorists will be unable to use the crossing to travel to and from Barrington Road during this period.
Advertisement
Access to the station, local businesses and Docwra’s Close will remain available, controlled by temporary traffic lights. Pedestrian routes, including across the level crossing, will remain open. A diversion route will be established for vehicles.
The works form part of the Melbourn Greenway scheme, which seeks to make walking, wheeling and cycling between Melbourn and Cambridge more straightforward and safer. The GCP states that Shepreth will benefit from new, more accessible crossing points, including one outside Shepreth Village Hall.
Additionally, new double yellow lines on Station Road will be introduced to reduce congestion and enhance safety near the level crossing. A new 20mph zone will extend from the Barrons Green / Fowlmere Road junction to Shepreth railway station.
The project also includes raised tables at key junctions on Fowlmere Road to reduce traffic speed and facilitate safer crossings. Further traffic-calming measures on Fowlmere Road will include speed humps, a reduced speed limit, and improved street lighting.
Advertisement
The plans and road closures have prompted strong reactions from readers. One commenter, Danieal wrote: “Another waste of money.”
Rhodabike adds: “Yet another village falling victim to the GCP’s anti-car, congestion-generating arrogance.”
Dagough states: “It is time someone got the GCP under control. They are pursuing a minority anti-car agenda in our villages. They are unelected zealots”
Trumplad says: “If you think this is a problem, wait until they close Long Road for 6 to 13 weeks!”
Advertisement
Freddly quotes: “‘Works also include raised tables…’ – it’s important that these are tall and steep enough to damage a 2026 SUV if taken at speed. The design of modern SUVs makes low, gentle ones ineffective. Making them steep will save lives.”
Nocyclinganywhere replies: “Have you thought about police and ambulance and fire appliances going over them , I don’t think that will will save lives when they have to slow down for them or find alternative routes.”
Whynot2 answers: “And what of the small city cars and small family cars are you personally going to pay for the damage that the cars may obtain from going over one of your tall speed bumps?”
Do you believe that the completed roadworks will benefit everyone in the surrounding areas? Comment below or HERE to have your say.
Finding true and lasting love is a top priority for many of us, but it’s not always easy to achieve. If you’re widowed or dating post divorce, you may not feel motivated to go on countless dates with new people. However, sex and relationship coach Angela Vossen believes there are practical ways to build your confidence.
How to find love
“The best way to find love is to enjoy life to the fullest, rather than forcing a relationship into your life,” Angela explains. “Stop looking for someone to complete you and start becoming someone you actually enjoy spending time with,” she adds. “Love finds its way to people who are already living, not to those who have put their lives on hold waiting for it to arrive.”
She adds that life-changing love rarely lands on your doorstep; it tends to turn up in the places you haven’t been yet. “Say yes to things that make you slightly uncomfortable. Join the club, attend the event, download the app you’ve been dismissing,” Angela adds. “And when you do meet someone interesting, be curious rather than trying to be impressive. Ask questions you actually want the answers to. Listen as though what they are saying matters, because if there’s real connection there, it does.”
With this in mind, here are 10 essential tips to finding love and building a fulfilling relationship.
Advertisement
10 tips for finding love
1. Prioritise self-love and confidence
It’s true that confidence can be incredibly attractive. When you care for yourself, it sets a precedent for how you expect others to treat you, too. There are lots of ways you can show yourself love, from doing things that bring you joy, to spending time with people that make you feel good, and taking care of yourself with exercise and nutrition.
When you feel good about yourself, you’ll be much more likely to attract like-minded people with a similar energy.
2. Focus on being yourself
The right person for you will love you exactly as you are, so always focus on being your authentic self when looking for love. While it’s natural to want to show a highlight reel of your life, don’t be afraid to be vulnerable too and share the less impressive parts that make you human. Trying to change or hide things about yourself to impress others may work in the short term, but genuine love should always be based on authenticity, not a fantasy. It’s worth remembering that the rough edges are often where trust and genuine connections are made.
3. Use online dating effectively
Online dating can be a very effective way of finding a potential romantic partner. Research from 2023 showed that 11.1 million people in the UK use dating sites. This figure is expected to rise to 12 million by 2028.
Advertisement
Telegraph Dating alone has helped tens of thousands of people start their online dating adventures, resulting in many happy and lasting relationships, not to mention weddings and babies.
4. Actively build connections
Aside from online dating, actively building new connections is a good way to enrich your life. When you don’t micro focus on solely finding love and instead focus on just getting out there and meeting new people, you’ll naturally expand your network and the likelihood of meeting a potential romantic partner.
Not sure where to start? Try out new hobbies, join clubs, and look at local volunteering events. This will help you naturally expand your social circle and opportunities to meet new people.
Read more:
5. Learn from past relationships
Everyone can learn something from past relationships. Whatever note you and your ex ended on, think about what went well and what didn’t. This will help you have a clear idea of what you want from your next romantic partner and the things you might change this time around.
Advertisement
6. Embrace vulnerability in love
Dating and meeting new people does require a certain amount of vulnerability, so if you’re still feeling guarded after the end of a relationship, you may need more time to work through those difficult feelings. But if you’re ready, consider what you’re comfortable sharing and at what point you might open up more. Sharing all of your vulnerabilities may not be something you do on a first date, but it’s an important way of deepening a relationship and building trust further down the line.
7. Seek support from friends and family
If you’re open to meeting someone new or have signed up to a dating site, tell your friends and family. Seeking this support and having people to talk about it with will not only give you greater accountability, but it will also help to navigate the ups and downs of dating life with those you trust the most.
How to build lasting love
If you’ve been dating for a while but are struggling to turn anything into a lasting relationship, it may be time to take stock of what you’re actually looking for. Here are a few pointers to consider:
8. Understand what loves means to you
Love can mean something slightly different to everyone so it’s a good idea to think about what it looks like for you. Perhaps it’s peaceful companionship and loyalty, or that big romance you’ve always dreamed of. Maybe it’s simply finding someone that makes you feel safe and understood. Write down a few things that immediately spring to mind or chat about it with a trusted friend. You may be surprised at what comes up.
Likewise, it’s important to think about what you want in a long-term partner. This will help you think more clearly when you start dating and meeting new people. It can also help to avoid falling into old patterns and missing relationship red flags. For instance, perhaps in previous relationships you never felt like a priority and want to find someone that truly values you. Or you really want a partner that enjoys new adventures and embracing life to the fullest. This will keep you laser focused on what you want and the key attributes and values to look out for.
10. Strengthen your communication skills
While some of us are great communicators and can perfectly articulate our feelings, others may need a bit of help. It’s important to communicate effectively from the start of your dating journey, from your first message to a potential match onwards.
When you meet someone new and go on dates, give yourself permission to speak openly. Communicate what you’re looking for and what your values are. This also works both ways so ask the same of your date and actively listen to their answers.
Advertisement
If you’re concerned about your communication skills, ask friends and family to give you some feedback. This will help you identify potential blind spots and make you aware of habits you have such as taking days to reply to a text, oversharing when nervous, or shutting down when asked about difficult topics such as divorce.
FAQs
Angela says that you’re probably ready for a committed relationship when you can answer yes to three things. Do I actually like myself? Can I hold space for another person’s needs without abandoning my own? Am I choosing this from desire rather than fear?
“That last one is the most important,” she says. “A lot of people pursue commitment because they are afraid of being alone, of being left behind, of what others will think. That’s a shaky foundation. A relationship entered from fear tends to produce a lot of anxiety and very little joy.”
Another thing Angela advises thinking about is if you can have a difficult conversation without it becoming a catastrophe. “Can you ask for what you need, hear something hard about yourself, sit with discomfort without lashing out or shutting down?” Angela explains that these are the behaviours a committed relationship requires.
Advertisement
“Readiness doesn’t mean you’re healed from everything or have no unresolved history. It means you’re self-aware enough to bring those things into a relationship without expecting a partner to fix them.”
Are you wondering if the feelings you have for someone are love or just infatuation? Angela says there are some key ways you can tell the difference. Infatuation, she says, comes with intrusive thoughts, butterflies, someone taking up all the available mental bandwidth in your brain. “That’s real, but it’s also temporary by design. It’s your nervous system doing its job,” she explains.
“What I’d look for underneath that is something quieter. Do you feel safe with this person? Do you like who you are around them? Can you be mundane together, not just electric? Are you genuinely rooting for their happiness, not just how it interacts with yours?” Love, she explains, in its more durable form is less a feeling and more a decision you keep making. “But the feeling matters,” she adds. “If you’re asking whether it’s love, pay attention to what your body knows before your mind catches up.”
“I understand why people ask this, but it’s the wrong question,” says Angela. “There’s no timeline, and the belief that there is one causes a lot of unnecessary suffering”. She adds that when we’re convinced we should have found it by now, we stop dating from a place of genuine interest and start dating from a place of urgency.
Advertisement
“That urgency is one of the most effective ways to repel the very thing you’re looking for,” she says. “In the meantime, don’t put the rest of your life on hold. Travel, take the course, move house, change career, do the things that are genuinely yours to do. People who are visibly engaged in their own lives are far more attractive than people who are visibly waiting.”
Angela stresses that the conditions under which love tends to arrive are curiosity, openness, and a life that’s full enough not to need it. “Create those conditions, and love becomes possible.”
Part of the reason that finding real love can seem hard is because we’ve been sold an idea of love as something that happens to us, rather than something we actively participate in and build. “Films end at the beginning with the promise of ‘happy ever after’ but they tend not to show what that happy looks like, how it changes over time, and sell the false idea that if it’s not for ever after, it wasn’t the real deal,” she explains. “Nobody’s making content about the Tuesday evenings when it’s all a bit flat and you choose each other anyway. Or the love that eventually ends not because it wasn’t real or wasn’t valuable but because we’ve now outgrown the version of ourselves that it went with.”
“There’s also the paradox of abundance,” she continues. “Dating apps mean we’re technically exposed to more potential partners than any previous generation, but that volume can create a consumer mindset where everyone is perpetually auditioning and nobody is committing”. She explains that the temptation to keep scrolling in case something better comes along can be corrosive, both to the people we’re meeting and to our own sense of what is enough.
Advertisement
Finally, it’s important to consider the internal work. “A lot of us carry relational patterns from early life that we’re not even aware of. We recreate familiar dynamics rather than healthy ones, then wonder why we keep ending up in the same place with different people,” she explains. “Finding love often requires understanding ourselves well enough to interrupt those patterns.”
If we’ve inspired you to get out there and meet someone special, you can kick-start your search with Telegraph Dating. With more than 220,000 single people, Telegraph Dating is the perfect place to find romance.
Neighbours claimed Jo Shaw had ‘been complaining to the police for some time’ before her death
An investigation will look into how police handled ‘years of calls’ from a Bristol mum who was killed in a ‘deliberate’ house explosion caused by her ex.
Advertisement
Jo Shaw, 35, reportedly ushered a child to safety shortly before the blast, which also killed her former partner Ryan Kelly, 41, on May 3, after he arrived at her address in Sterncourt Road with an explosive device, neighbours say.
The mum was described as telling a child to leave the home to play outside on a trampoline when an argument broke out between her and Kelly, previously convicted for serving as a foot soldier in a local drugs gang, shortly before the explosion, the Mirror reports.
The Independent Office for Police Conduct (IOPC) confirmed it was investigating the interaction between Ms Shaw, Kelly and Avon and Somerset Police. Reports suggest that the mum had contacted the force to report her ex’s dangerous behaviour on several occasions beforehand.
Advertisement
“She had been complaining to the police for some time before this incident, and he had been harassing her,” neighbour Stuart Blanchard previously told the Mirror.
“I’d heard the shouting before while having breakfast, something like ‘get out, get out’ but there’s something every week in this area so I didn’t go out.
“Then there was a bang, it shook my front door. But my friend heard the kicking so went over. I thought it was a gas explosion so stayed inside. It’s a shock for everyone because they were a really nice family,” he added. “I cannot believe it has happened.”
Avon and Somerset Police last contacted Ms Shaw four days before the explosion, according to the IOPC, which added its investigation would look at past incidents over a five-year period, from May 2021.
Advertisement
“My thoughts and sympathies are with everyone affected at this very difficult time,” said IOPC director Derrick Campbell. “We are independent of the police, and it is important that we carry out a thorough investigation, to fully establish the circumstances of what happened prior to the tragic events of May 3.
“There is a significant history of police involvement in relation to Mr Kelly’s behaviour, including allegations of stalking, harassment and assault which we need to examine as part of our investigation.
“We are reviewing extensive documentation detailing that history as part of our inquiries. We will be keeping all interested parties updated as our investigation, which is at an early stage, progresses.”
Advertisement
Ensure our latest news and sport headlines always appear at the top of your Google Search by making us a Preferred Source. Click here to activate or add us as Preferred Source.
The cause of the explosion is currently being treated as deliberate by Avon and Somerset Police – with Ms Shaw’s death therefore being recorded as a homicide. No one else is being investigated in connection with her death.
Three other people, including a child, sustained minor injuries in the blast. The force had previously said a call was received from a person inside the house at 6.17am reporting a domestic-related incident, saying a man they knew had forced entry to the house.
The caller remained on the line while officers were dispatched to the house and at 6.30am the caller told police the man was believed to be in possession of an explosive device. About two minutes later there was an explosion at the property, in which Ms Shaw and Mr Kelly died.
The east coast has seen a hail and thunderstorm leading to flash flooding.
Whitby has been particularly affected with many roads in the town flooded.
According to the Met Office the weather for the region for the rest of the week remains unsettled and rather cool throughout, with rain and showers.
Advertisement
This Evening and Tonight:
Any heavy showers will soon clear eastwards, leaving a largely dry night with clear spells developing for a time. Staying generally cloudy across western areas, with a few light showers. A mild and breezy night. Minimum temperature 10 °C.
Wednesday:
Increasingly cloudy, ahead of a band of rain sweeping east across the region. Sunny spells and blustery showers in the afternoon, with hail and thunder. Showers persisting in the evening. Maximum temperature 18 °C.
North Yorkshire Police is investigating the disappearance of the juvenile bird after its satellite tag stopped transmitting in the North York Moors.
Following analysis by the National Wildlife Crime Unit, the disappearance of the eagle, which fledged in 2025 and has roamed widely across England this spring, is being treated as suspicious and an investigation is under way, police said.
The bird arrived in the western side of the North York Moors on April 30, and its tag did not communicate overnight into May 1, with no further transmissions since.
Advertisement
The white-tailed eagle, known as G834, was the first to be born in the wild in Dorset in 240 years, as part of a project to bring the birds of prey back to England.
The eagles, nicknamed flying barn doors because of their wingspan of up to 8ft (2.4m), were once widespread in southern England until the 18th century when persecution led to them being wiped out in the region.
The project by Forestry England and the Roy Dennis Wildlife Foundation began reintroducing white-tailed eagles on the Isle of Wight in 2019, and has released 45 eagles since then.
The birds have previously been reintroduced in Scotland.
Advertisement
The first pair of Isle of Wight eagles bred successfully in 2023, fledging the first chick to have been born in the wild in England for more than 240 years.
A further five chicks have been born in the wild since, and last month the government announced the scheme would receive a boost with up to 20 young white-tailed eagles being released over three years in Exmoor National Park.
A statement on behalf of the Forestry England and Roy Dennis Wildlife Foundation reintroduction project said: “We are deeply shocked and saddened by the suspicious disappearance of this young white-tailed eagle.
“It was the first to be bred in the wild in Dorset for 240 years and was beginning to really settle into the landscape.
Advertisement
“The return of this lost species to England has so much support from the public and we know that many people will be devastated to hear this news.”
The conservationists said satellite data showing the birds’ minute-by-minute movements was monitored every day and any suspicious or unusual data was always investigated.
The statement said: “These special birds are helping people connect with the natural world and showing how with a little bit of help nature can thrive.
“Thank you to everyone for their continued support and we encourage anyone who has information that may help the police investigation to come forward.”
Advertisement
Despite concerns in some quarters that the birds could prey on livestock such as lambs, a study into the food the Isle of Wight birds are eating reported in 2024 that they were targeting prey such as cuttlefish, rabbits, fish and other birds, and there were “no conflicts” with farming.
But the birds – whose return has faced opposition from some in the gamebird shooting community – have suffered persecution, with police investigating the disappearance of three birds last year in Sussex and Wales in suspicious circumstances.
And in 2022, two released white-tailed eagles from the reintroduction scheme were found dead, prompting police investigations in Dorset and the Isle of Wight.
Today, Amanda Martin MP welcomed the new branded Great British Railways train at Waterloo Station. Amanda met with the Great British Railways team to view the new train designs in person as Great British Railways moves full steam ahead, with more services returning to public ownership this week and an exciting new national brand being rolled out across the country.
Debenhams has firmly cemented itself in the tapestry of British shopping. If you love a bargain, you’re in the right place, as there’s a whole host of offers available at Debenhams, including impressive discounts of up to 75 per cent. We’ve got all the information on how you can save with the latest discounts and voucher codes.
Save up to 15 per cent with a promo code
You can almost always find a Debenhams discount code for between 10 and 15 per cent off. These tend to change weekly and are usually applicable to specific brands or categories, such as women’s fashion or footwear.
Advertisement
Up to 70 per cent off in the payday sale
Every payday, you can expect big price drops of up to 70 per cent on all departments. In the latest sale, there is at least 20 per cent off almost all beauty, up to 70 per cent off outdoor furniture, clothing, shoes and more – plus an extra 25 per cent off select products. It’s worth checking back towards the end of each month for new additions and flash sales across particular products or categories.
Students can save an extra 10 per cent across all Debenhams categories (Debenhams)
Shop pre-loved fashion
The Debenhams preloved section enables you to enjoy designer fashionwithout the hefty price tags. Save up to 50 per cent on the cost of luxury items such as handbags, jewellery and watches, all with a 100 per cent authenticity guarantee and condition guide, so you know exactly what to expect. Delivery is free and you also get a 28-day returns period in case you change your mind.
Advertisement
10 per cent off with Student and NHS discounts
If you’ve got your heart set on a full-price find or haven’t got a discount code to use, you can still save on your next Debenhams shop. NHS workers will get a helpful 10 per cent discount on full-price goods at Debenhams, as will students, simply by verifying student status through Student Beans.
Free delivery
At Debenhams, standard delivery starts from £3.99, but the good news is that we often see a free delivery code or £1 delivery code most weeks.
Advertisement
Debenhams’ loyalty and subscription perks
Join the Debenhams beauty club
The Debenhams beauty club is an easy way for you to build points and take advantage of exclusive perks and offers. The loyalty scheme works in a tier structure, with the following point systems as you work your way up:
Enthusiast (tier 1) – 500 points upon registering, three points for every £1 spent on beauty and a 10 per cent birthday discount.
Pro (tier 2) – spend between £101 to £299 within a year to be promoted to tier two, with four points per every £1 spent on beauty and a 15 per cent birthday discount.
Icon (tier 3) – spend more than £300 on Debenhams beauty products and you reach the top tier, receiving five points for every £1 spent on beauty and a 20 per cent birthday discount.
Debenhams unlimited
If you’re a frequent Debenhams shoppers, it might be worth investing in a Debenhams Unlimited membership for just £14.99 a year. Members get increased benefits such as VIP member days, exclusive offers and unlimited next-day delivery.
Advertisement
Debenhams unlimited members get exclusive offers and unlimited next-day delivery (Debenhams)
Delivery
Standard delivery (within four days) starts from £3.99, or you can opt for super-saver, which takes slightly longer to arrive (between five to seven days). If you’re in a rush, next-day shipping is available for £5.99 or express (arrival within two days) for £4.99.
Returns explained
Debenhams has a 28-day returns period, as long as items are unused, in original packaging and with tags still attached. There is a £1.99 returns fee, so bear that in mind when ordering. You can opt for a credit note or refund back to your original card.
To start your return, simply log in to the returns portal using your email address and order number.
Advertisement
Online shopping made easy
Debenhams makes online shopping easier than ever, with tools and advisors specialising in a number of different services, including beauty advisors, online quizzes and virtual try-ons. This helps you find the styles and shades that suit you best, without having to worry about lengthy returns or extra fees.
How do I redeem a Debenhams discount code?
Click the “See code” button on your chosen offer and copy the code that pops up on your screen. You’ll then be redirected to the Debenhams website, or you can switch back to your original tab to complete your order. On the order summary page, you will see a promo code box – paste your code here and hit apply to enjoy your discount.
Advertisement
What is the Debenhams marketplace?
Similar to Amazon and eBay, Debenhams works with other sellers to bring you a wider range of products. This means not everything comes directly from the Debenhams warehouse. However, you will be able to see clearly on the product listing whether the item is from a third-party seller.
Whether it’s to bring you news on Amazon Prime Day and Black Friday, or the latest on the Boxing Day sales, The Independent is a trusted consumer champion. Our expert deals team is always on the lookout for ways to save you money and fill you in on the products worth buying, so you can trust we’ll only bring you true deals, from brands that we trust.
Losing weight is hard. Keeping it off is often even harder.
Research has shown that most people who intentionally lose weight regain at least some of it within a few years. This is often attributed to lack of “willpower”, but the evidence actually shows that after we lose weight, the body undergoes a range of biological changes that encourage weight regain. This includes increased hunger, changes in metabolism and shifts in hormones involved in appetite regulation.
For this reason, finding ways to help people maintain weight loss is a key area of research.
Advertisement
A new study published in Nature Medicine suggests that one particular gut microbe may help to prevent weight regain.
The bacterium, called Akkermansia muciniphila, is an abundant species in the human gut microbiome. It lives in the mucus layer that lines the gut. It’s able to feed on mucin (the proteins and sugars that make up this mucus), and is thought to play a role in maintaining the gut’s protective barrier and can also influence metabolism.
Studies in humans have shown that higher levels of Akkermansia muciniphila are linked with better metabolic health, including improved blood sugar control, which reduces the risk of developing health problems such as type 2 diabetes. On the other hand, lower levels of Akkermansia muciniphila are observed in people with obesity and type 2 diabetes.
Advertisement
This recent study investigated whether supplementing people with Akkermansia muciniphila after weight loss could help limit subsequent weight regain.
The trial involved 90 adults who were overweight or obese. Participants followed a low-energy diet for eight weeks. This consisted of meal replacement soups and shakes totalling 800-900 calories per day.
After this phase, participants who lost at least 8% of their body weight were then randomly assigned to receive either a placebo or daily supplements containing pasteurised Akkermansia muciniphila for 24 weeks. They were also instructed to follow a healthy diet that aligned with Dutch dietary guidelines, but were told they could eat as much or little as they wanted.
This study did not use live Akkermansia muciniphila bacteria. Instead, they used a pasteurised version (meaning the bacteria had been heat-treated and were no longer alive). This may sound counterintuitive, but previous research suggests that some of the beneficial effects of probiotics, including A muciniphila, may come from components of the bacterial cell rather than live microbes. Pasteurisation may even enhance the microbe’s effects.
By the end of the study, the group receiving Akkermansia muciniphila had regained significantly less weight than the placebo group. On average, those taking the supplement regained around 1.2kg, compared with 3.2kg in the placebo group. This suggests that supplementation slowed, but did not fully prevent, weight regain after initial weight loss.
The researchers also observed some improvements in some cardiometabolic markers, including improved insulin sensitivity (meaning the body is responding to insulin more effectively) in the supplemented group.
The gut microbiome and body weight
The microbiome is highly complex. It is influenced by diet, exercise, sleep, medications and many other factors. As a result, microbiome-based therapies are unlikely to be simple, one-size-fits-all solutions.
Although the findings are encouraging, the study was relatively small and only lasted six months after the initial weight-loss phase. We still do not know whether the effects would continue over longer periods.
Advertisement
There are also questions about who is most likely to benefit, as participants with lower baseline gut levels of Akkermansia appeared to show greater cardiometabolic improvements. This highlights a broader challenge in microbiome science: people’s gut microbiomes vary enormously, and treatments that work well for one person may have little effect in another.
The study also involved substantial dietary intervention and support, including the provision of a meal replacement plan for the initial weight loss, and support from dietitians throughout the entire study period. So the microbe was not tested in isolation from lifestyle changes, nor should it be viewed as a substitute for them.
It’s also worth noting that several authors declared links to the company producing the supplement used in the trial. While such collaborations are common in translational research (studies which test lab findings in real people to understand health benefits), independent studies will be important to confirm and build on these findings.
That said, the microbiome is still a fascinating and increasingly important area of research with clear links to many aspects of human health. Our understanding of it is still developing. However, research so far shows that the microbiome plays key roles in metabolism and immunity, meaning it can influence both health and the development of disease.
Advertisement
Many probiotic supplements currently marketed to consumers have limited evidence behind them. Although studies like this suggest that carefully targeted microbiome therapies may have potential to eventually be used as part of weight-maintenance strategies, much more research is needed.
It may even be possible to support and increase Akkermansia muciniphila without supplementation. Diet plays an important role in shaping the microbiome. Diets rich in fibre, particularly prebiotic fibres (a type of dietary fibre that feeds beneficial gut bacteria), can help create an environment in which beneficial bacteria, including Akkermansia muciniphila, can thrive.
These fibres are found in foods such as onions, garlic, leeks, asparagus and many whole grains. Plant foods high in polyphenols (naturally occurring plant compounds that can protect cells against damage and inflammation) – such as berries and grapes – may also promote its growth.
Advertisement
For now, the findings from this study add to growing evidence that body weight is influenced by a complex interplay of biological, environmental and behavioural factors. They also contribute to an increasingly clear picture of the gut microbiome as an important regulator of metabolism and health.
You must be logged in to post a comment Login