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NewsBeat

Thursday’s briefing: Villa win Europa League and Southampton lose appeal

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Thursday’s briefing: Villa win Europa League and Southampton lose appeal

Aston Villa secured their first trophy in 30 years with an emphatic 3-0 Europa League final win over Freiburg.

Southampton lost their appeal for expulsion from Saturday’s Championship play-off final, while David Seaman has called for Mikel Arteta to be honoured with a statue if the club follow up their Premier League triumph by winning the Champions League.

Classy Villa cruise to Europa League glory

Aston Villa ended their 30-year wait for a trophy as they strolled to an emphatic 3-0 victory over Freiburg in the Europa League final in Istanbul.

The Prince of Wales was in attendance to see his beloved side win their first silverware since the League Cup in 1996.

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Villa’s quality shone through with a pair of unstoppable strikes at the end of the first half from Youri Tielemans and Emiliano Buendia.

Villa started to flex their muscles and Morgan Rogers added a third which sparked jubilant scenes on the final whistle.

Southampton play-off appeal dismissed

Middlesbrough will play Hull in Saturday’s Championship play-off final after Southampton lost their appeal against their expulsion for ‘spygate’.

An independent commission imposed the penalty after Saints admitted three spying charges, including observing a Boro session ahead of the semi-final first leg.

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The commission also reinstated Middlesbrough and denied Southampton the chance of a shot at promotion to the Premier League, worth an estimated £200million at a minimum.

Saints chief executive Phil Parsons called it “manifestly disproportionate” to any other sanction handed down in the history of the English game, but their appeal was rejected.

Arteta deserves statue if Arsenal win Champions League, says Seaman

Former goalkeeper David Seaman believes Mikel Arteta should be honoured with a statue outside the Emirates Stadium if he completes Arsenal’s “best season” by winning the Champions League.

The Gunners’ 22-year wait for the Premier League title is over, which sparked wild celebrations, among the players and staff at their training base, as well as thousands of supporters at the Emirates.

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Thierry Henry, Dennis Bergkamp, Tony Adams, former managers Arsene Wenger and Herbert Chapman, and the club’s president Ken Friar, are all immortalised with bronze statues outside the ground.

And when asked if Arteta could also be recognised if Arsenal see off Paris St Germain in the Champions League final on May 30, Seaman said: “If that does happen, it is going to be the best season in the club’s history, so why not?

“I just feel this team can get better and better. The club has never won the Champions League before and that would be one hell of a double. It is a big ‘if’, but it would be epic.”

Haaland: Man City ‘should be angry’

Erling Haaland has urged Manchester City to use the pain of missing out on the Premier League trophy for a second successive year to fuel next season’s title challenge.

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Arsenal were crowned champions after second-placed City were held to a 1-1 draw at Bournemouth.

“The whole club should use this as motivation now,” said Haaland. “We should be angry, we should feel a fire inside our belly because it’s not good enough. It’s gone two years now, it feels like forever.”

What’s on today?

Arteta is due to speak for the first time since Arsenal won the Premier League when he faces the media at the club’s London Colney headquarters.

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Katie Price shares cryptic messages after twist in Lee Andrews’ disappearance

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Manchester Evening News

Katie Price shared a series of cryptic late-night posts on Instagram amid the ongoing disappearance of her husband Lee Andrews, who has been formally reported missing to the UK Government.

Katie Price has taken to social media to share a series of late-night posts, fuelling speculation over whether her cryptic messages are linked to the disappearance of her husband Lee Andrews.

The Dubai-based businessman vanished last week, leaving former glamour model Katie, 47, and her husband’s family frantically searching for him.

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In the early hours of Thursday (May 21), Katie posted to Instagram, sharing three seemingly pointed messages with her followers.

The first image read: “I’M NOT OVERWHELMED BECAUSE I CAN’T HANDLE IT. I’M OVERWHELMED BECAUSE I DO HANDLE IT. ALL. OF. IT.”

It continued: “ALL. THE. F***ING. TIME.”

Her second post was the one that really set tongues waggig, featuring the quote: “Sometimes you just have to accept the situation and say, it’s okay, it happens, it’s life”.

Her third and final shared message read: “Focus on yourself, because nothing is more powerful than a woman who knows her worth, chases her goals, and dares to dream big.”

The trio of late-night posts were uploaded via her Instagram stories, meaning followers were unable to comment publicly. Yet, given Katie’s previous social media activity surrounding her husband’s shocking disappearance, it is clear that the public is still very much in the dark about what is actually going on.

Katie last had contact with the 43-year-old Dubai-based businessman on Wednesday evening. She sounded the alarm the following day. “Lee was trying to get through the boarder at Hatta, this is so discombobulating, his location went off at 10.03pm on Wednesday night, that’s the last contact anyone has had – his family and myself. This is the third day now,” she said at the time.

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In the wake of Lee’s kidnapping claims, a number of experts and insiders have voiced doubt about his version of events. Yet despite the apparent communication blackout during the supposed abduction, it has emerged that Lee has been using his mobile phone — just not to contact Katie.

Lee’s kidnapping ordeal has raised further questions for one seasoned investigator, with certain elements of his account failing to add up for investigative journalist Mark Williams-Thomas. Mark is well known for his expert analysis of some of Britain’s most prominent missing persons cases, including the tragic deaths of Jay Slater and Nicola Bulley.

He has now shared his thoughts on the unfolding situation, and the expert investigator appears far from convinced by several elements of Lee’s story. He said: ” Katie Price says she spoke to him on Wednesday, and shortly after 10 o’clock he was in the back of a van. He says they’re coming back.

“He had a hood over his head, his hands were tied, not by handcuffs, but he had managed to make a FaceTime call to her and didn’t tell her to phone the police. And he himself didn’t phone the police and didn’t give any more information.

“And since then, apparently his phone has gone dead, although he has, or someone has, managed to go onto his social media and delete some informational posts that are on there. So that’s slightly strange, isn’t it?”

Mark raised concerns over whether the alleged abduction had been reported to the authorities and what action was being taken. “Has this matter been reported to Dubai police? And in which case, given the information that Katie Price is saying, they’d be treating it as really serious, wouldn’t they? If it’s a potential kidnap,” he added.

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Mark also accused Lee of “playing some ridiculous game” and suspects the situation is far more straightforward than an abduction. Speaking on TikTok, the investigative journalist said: “Well, has he been abducted? What’s the story behind it?

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“The newspaper says that he’s not being kidnapped, he’s in hiding, he’s ghosting Katie Price and has been doing so for the past six days. It’s got to a situation now whereby, you know, I don’t think anyone believes Lee Andrews has been abducted or kidnapped in any way at all.

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“He’s obviously playing some ridiculous game, but it’s attracted the media, and it will no doubt unfold more over the forthcoming days. Clearly this is a man who’s got some serious issues.”

Lee’s whereabouts remain unknown. He has also been officially registered as missing by the UK Government, with the Foreign Office confirming it is offering support to his family after a missing persons report was lodged.

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Newscast – Has The UK Softened Russia Oil Sanctions?

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Newscast - Epstein Files: New Mandelson and Andrew Allegations

Available for over a year

Today, the government announced a watering down of Russian oil sanctions as fuel prices rise from Iran war.

Adam is joined by Chris and Faisal to discuss that, as well as the cut in fuel duty and Wes Streeting’s resignation speech in the House of Commons.

And Emma Pinchbeck, CEO of the Climate Change Committee, speaks to Adam about a new report on climate adaptation in the UK.

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You can now listen to Newscast on a smart speaker. If you want to listen, just say “Ask BBC Sounds to play Newscast”. It works on most smart speakers.

You can join our Newscast online community here: https://bbc.in/newscastdiscord

Get in touch with Newscast by emailing newscast@bbc.co.uk or send us a WhatsApp on +44 0330 123 9480.

New episodes released every day. If you’re in the UK, for more News and Current Affairs podcasts from the BBC, listen on BBC Sounds: https://bbc.in/4guXgXd

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Newscast brings you daily analysis of the latest political news stories from the BBC. The presenter was Adam Fleming. It was made by Chris Gray with Gabriel Purcell-Davis and Shiler Mahmoudi. The social producer was Joe Wilkinson. The technical producer was Mike Regaard. The assistant editor is Chris Gray. The senior news editor is Sam Bonham.

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England vs New Zealand: Alice Capsey and Lauren Bell star as hosts win T20 opener

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Capsey & Kemp

Earlier this week, England’s World Cup preparations were dealt a blow with captain Nat Sciver-Brunt’s calf injury ruling her out of this series and the following three matches against India.

They have been guilty of relying too much on Sciver-Brunt’s batting brilliance in recent years, which will add an element of added pleasure for Charlotte Edwards as she watched two 21-year-olds put together a mature, match-winning stand.

Capsey, who usually bats at number three, was opening for the first time for England in this format but stepped up seamlessly as Wyatt-Hodge awaits the birth of her child.

She played to her strengths by dismantling New Zealand’s pace attack flawlessly, including back-to-back sixes off Jess Kerr in the 15th over, while calmly negotiating the spinners with singles.

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Though it remains unclear who will make way in the side when Sciver-Brunt and Wyatt-Hodge return, World Cup winner Alex Hartley says England must find a way to keep Capsey in.

“I think she is in England’s best XI, the way she’s adapted her game,” Hartley said on BBC Test Match Special.

“When she came onto the scene as a 16-year-old she set the world alight, we all knew the talent that she had then. She had a little bit of a dip in form, she was on TV more and players started to to work her out.

“But she’s adapted her game, she was brilliant in the 50-over World Cup and she got England out of a lot of trouble a number of times.”

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Capsey believes her game has improved since she had the opportunity to spend time working on her skills, away from the pressures of playing.

“That three-month block at the beginning of the year was amazing, just to get some proper skills development, which I’ve probably not had for the last couple of years,” said Capsey.

“I’ve worked on quite a few different areas of my game, I feel really comfortable at the crease, really calm – I think it showed today, I think I was two off eight, and just that composure to know I can catch up and really believe that as well.”

After fellow opener Sophia Dunkley skied a catch for eight and Maia Bouchier was cleaned up by Bree Illing, Capsey added 43 with former captain Knight before Kemp injected some late energy into the chase with her 20-ball knock as the threat of rain loomed.

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With the ball, the roles of England’s attack is clear. Bell continues to shine in her leadership role while Smith dominated the powerplay, claiming the key scalp of skipper Melie Kerr, who was caught at mid-off which may have contributed to the rest of the batters’ timid approach to the spinner.

However, Ecclestone was also targeted by New Zealand in the third ODI at Cardiff which could be a trend used by opposition sides at the World Cup.

Devine was immediately on the attack with those three massive leg-side blows, but the return of Gibson and Kemp to bowling after their respective back injuries ticks off another key part of Edwards’ puzzle.

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Southampton fume after losing appeal over ‘disproportionate’ Spygate punishment | Football

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Southampton fume after losing appeal over 'disproportionate' Spygate punishment | Football

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Freiburg 0-3 Aston Villa: Unai Emery wins a fifth Europa League final as Villa end 30-year trophy wait

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Unai Emery has won five European trophies as a manager

The extent of Emery’s Aston Villa revolution cannot be underestimated.

When the Spaniard took charge on 1 November 2022, Villa were 16th in the Premier League – two places and one point above the relegation zone.

They went on to win 15 of their 25 league games to finish seventh and earn a spot in European competition for the first time since 2010-11.

In his first full season, Emery secured Champions League football for Villa for the first time since 1982–83. His side also won 15 consecutive home league games – the most in their 151-year history.

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And now, with Champions League football secured once again, Villa are champions on the continent for the first time in a generation.

Former Villa midfielder Mark Albrighton told BBC Radio 5 Live that Emery has “taken Villa to the next level”.

He said: “There are going to be times when you have highs and lows, that is the nature of football.

“Villa have experienced some of those lows but now they are on a massive high. Unai Emery was a step up in terms of what they had before.”

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Ashley Young, another ex-Villa player, also told Radio 5 Live: “As soon as Unai Emery came in to Aston Villa, the players saw what he had done in his career, saw the Europa Leagues he had won and the clubs he had managed.

“Emery is a born winner, especially in this competition when he has shown it time and time and time again. Put his name up there alongside Ancelotti and Mourinho.

“He’s put this club back into Europe, back into the Champions League. If you had said when we were in 16th position in the Premier League that he would come in and win the Europa League, not one player would think that would be true. He’s just got a way.”

There are more teams now who work the way Emery works, who study what he studies and have managers who stay up late watching football they don’t really have to watch.

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But Emery will continue to go one step further – as he always does.

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BBC expert warns common garden plant can be ‘toxic’ for pets

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Wales Online

Vet Dr James Greenwood shared an easy distraction that can also help stop your dogs from digging up the garden

Dog owners who spot their four-legged friend digging in the garden or casually munching on garden waste might not consider it concerning, but while addressing viewer queries on BBC Morning Live, one veterinary surgeon explained when this behaviour could prove potentially fatal for your animals.

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One caller, Steve, mentioned that his dog frequently eats soil during walks and from his planted containers in the garden. Dr James Greenwood explained this could be a condition called Pica, which can also affect humans, and it may be hazardous depending on the varieties of plants in your garden.

He stated: “The main thing here really is to just be worried about what he might find in that soil. So, one of the things that I’d be quite sort of nervous about is bulbs.

“Lots of the plant bulbs that we have in our gardens can actually be quite toxic to dogs. So just be a little bit aware of that.”

This includes some common springtime plants according to the RSPCA:

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  • Daffodils
  • Tulips
  • Bluebells
  • Foxglove
  • Azaleas and rhododendrons

These can trigger various symptoms in animals, from digestive problems to tremors, drooling, vomiting and diarrhoea. RSPCA guidance cautions: “In some cases, just licking pollen off their paws or fur can cause a reaction. The bulbs of many plants are particularly toxic.”

Dr James explained that pica happens when animals consume something non-edible, from concrete to plastic and soil. He observed this can be connected to medical conditions and if it’s accompanied by symptoms such as vomiting, diarrhoea or weight loss and lethargy then it’s advisable to arrange a veterinary examination.

However, if your dog isn’t displaying these symptoms or digging up toxic plants, the vet confirmed there’s “no real harm” in dogs playing or consuming some soil, apart from it ruining your garden. But Dr James had a solution for that as well.

“If you actually lean into that and give him something to dig, a sand pit, for example,” he said. “You could bury some of his toys or treats and let him go and dig in that that is less likely hopefully to to go for the tubs.”

The vet pointed out that occasionally dogs may seem to be ‘eating’ soil but are in fact just using their muzzle as an additional ‘paw’ in their digging efforts.

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Republicans consider dropping security money request for Trump’s ballroom

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Republicans consider dropping security money request for Trump's ballroom

WASHINGTON (AP) — Republican senators are considering whether to drop a proposal for $1 billion in security money for the White House complex and President Donald Trump’s ballroom after it has failed to win enough party support on Capitol Hill.

Pressured by the White House, Republicans have tried to add the money to a roughly $70 billion bill to restore funding to U.S. Immigration and Customs Enforcement and the Border Patrol. But the security proposal has met with backlash from some GOP lawmakers who are questioning the cost and the lack of detail from the White House and U.S. Secret Service about how the taxpayer dollars would be used.

Sen. John Kennedy, R-La., said Wednesday that the bill was “back to square one” without the security money because “the votes are not there.”

Sen. Thom Tillis, R-N.C., said the effort to add the security package to the bill was a “bad idea” and he does not think there is enough backing to pass it, even if it were reduced.

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The text of the bill has not yet been released. But Senate Majority Leader John Thune, R-S.D., acknowledged “ongoing vote issues” as leaders try to measure Republican support, as well as “ongoing parliamentarian issues” as they try to figure out what will be allowed in the bill under the chamber’s rules.

The wrangling comes as Democrats have criticized Republicans for trying to fund Trump’s ballroom when voters are concerned about basic affordability issues — and as some GOP lawmakers have grown increasingly frustrated with Trump. Several GOP senators have spoken out against the administration’s $1.776 billion settlement fund designed to compensate Trump’s allies who believe they have been persecuted, and many were upset by the president’s endorsement Tuesday of Texas Attorney General Ken Paxton in the party primary runoff next week against Sen. John Cornyn.

“There’s always a consequence with taking on United States senators,” Thune said Wednesday. The president “obviously has his favorites and people he wants to endorse and that’s his prerogative. But what we have to deal with up here is moving the agenda, and obviously that can become slightly more complicated.”

Republicans could set parameters on Trump’s settlement fund

The “anti-weaponization” fund, part of a settlement that resolves Trump’s lawsuit against the Internal Revenue Service over the leak of his tax returns, has unexpectedly become one of the main complications in the bill. Democrats said they would force votes to block it or place restrictions on it.

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Democrats have an opening because Republicans are trying to pass the immigration enforcement bill through a complicated budget process that requires a long series of amendment votes. Democrats are considering multiple amendments potentially to block that new fund outright or to ban any payments to Trump supporters who harmed law enforcement officers in the Jan. 6, 2021, attack on the Capitol.

Those amendments, along with others, could pass as a growing number of Republicans have voiced reservations about the fund. So Republicans are now discussing their own last-minute add to head that off, potentially placing some parameters on the settlement and who could receive compensation, according to two people with knowledge of the private discussions who requested anonymity to discuss them.

Thune — who said Tuesday that he is “not a big fan” of the settlement and doesn’t see a purpose for it —- said Wednesday that any new language potentially putting restrictions on the settlement is “a work in progress.”

It’s unclear how any Senate Republican changes would be received in the House, even as some Republicans there have also criticized the settlement.

House Speaker Mike Johnson, R-La., said Wednesday that the House will pass the bill “whatever form it takes.”

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Tensions rise between Senate and White House

As Republicans challenged the settlement and parts of his agenda, Trump unloaded on the Senate in a social media post.

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He urged Republicans to fire the Senate parliamentarian, Elizabeth MacDonough, who said over the weekend that parts of the $1 billion security proposal cannot remain in the ICE and Border Patrol bill. Trump also renewed his long-standing calls for the Senate to pass the SAVE Act, a Republican bill that would require all voters to prove U.S. citizenship, and to end the Senate filibuster.

Republicans need to “get smart and tough,” Trump said, or “you’ll all be looking for a job much sooner than you thought possible!”

While they have been loyal to Trump on most issues, Senate Republicans have resisted his repeated calls — even in his first term — to kill the filibuster, which triggers a 60-vote threshold in the Senate.

Hanging over the growing GOP rift is Trump’s surprise endorsement of Paxton. That intervention has Republican senators privately fuming that it could cost them their majority in November as they view the incumbent, Cornyn, as the better candidate in the November general election.

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Secret Service request falters as Republicans want more detail

Under the Secret Service request, about $220 million would pay for security improvements related to the ballroom. The rest would go for a new screening center for visitors, training and other security measures.

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Tillis said the bill should not have included the other security improvements “because it’s just giving everybody the ‘billion-dollar ballroom.’”

Several other Republicans in the House and Senate have questioned the request, and senators left a briefing with the director of the Secret Service last week saying they needed a lot more information.

People “can’t afford groceries and gasoline and healthcare, and we’re going to do a billion dollars for a ballroom?” asked Louisiana Sen. Bill Cassidy, who lost reelection in his GOP primary on Saturday after Trump endorsed one of his opponents.

Left in the bill is the money for ICE and Border Patrol, which Democrats have blocked for months in protest of the Trump administration’s immigration enforcement crackdown.

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Democrats demanded reforms for the agencies, but negotiations with the White House yielded little progress. So Republicans are using the complicated budget maneuver called reconciliation — the same process that allowed them to pass Trump’s tax and spending cuts bill last year — to fund the agencies through the end of Trump’s term with a simple majority and no Democratic votes.

Still, passage requires signoff from the parliamentarian, and unity from Republicans.

“We’re working on it,” Thune said as he left the Capitol on Wednesday evening.

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AP Congressional Correspondent Lisa Mascaro contributed to this report.

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Iran-US war latest: Trump says Netanyahu will ‘do whatever I want’ after phone call with Israeli PM

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Iran-US war latest: Trump says Netanyahu will ‘do whatever I want’ after phone call with Israeli PM

Iran war briefing for Thursday 21 May:

  • Donald Trump has claimed Israeli prime minister Benjamin Netanyahu will do whatever is asked of him, insisting the pair are on the same page over negotiations to end the Iran war.
  • Trump said he was “in no hurry” to make a deal to end the war. He said the United States was ready to proceed with further attacks on Tehran if Iran did not agree to a peace deal, but suggested Washington could wait a few days to “get the right answers.”
  • Iran’s foreign minister Esmaeil Baghaei told news agency Nour News: “We have received US Views and are reviewing them”.
  • Pakistan ‌continued to mediate exchanges ‌of messages ‌between Tehran and Washington, Baghaei said, ⁠adding that several rounds of communication had taken place based on ‌Iran’s ​original ‌14-point framework.
  • Iran’s Islamic Revolutionary Guard Corps has threatened to push the war “beyond the region” if the US or Israel resume attacks, promising “crushing blows … in places you cannot even imagine.”

Stuti Mishra21 May 2026 04:10

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Can supplements containing NMN, NAD+ and resveratrol really slow ageing? Here’s what the evidence says

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Can supplements containing NMN, NAD+ and resveratrol really slow ageing? Here’s what the evidence says

As more people look for ways to stay younger for longer, the supplement industry has moved beyond creams and cosmetic fixes to something more ambitious: products that claim to slow ageing by acting on cellular processes.

Among the most heavily marketed compounds are NAD+, NMN and resveratrol, often described as supporting cellular repair, energy production and healthy ageing. But what do they actually do, where are they being used, and how strong is the evidence?

To make sense of the claims, it helps to separate three things: the molecule NAD+, the compounds sold to raise it, and the products, such as supplements, creams and serums, that contain them.

Nicotinamide adenine dinucleotide, or NAD+, is a coenzyme found in all living cells. A coenzyme is a helper molecule that allows enzymes to carry out chemical reactions in the body. NAD+ plays an essential role in energy metabolism, DNA repair, inflammation and the activity of a family of proteins involved in cellular stress responses.

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NAD+ levels tend to decline with age, although this decline is complex and may vary between tissues. Lower NAD+ availability has been linked to reduced mitochondrial function, meaning reduced activity in the cell structures that help produce energy. This is one of the biological changes associated with ageing.

NAD+ in creams and serums

NAD+ has begun appearing in skincare creams and serums, but the evidence is even less developed here than it is for supplements.

While NAD+ is important for skin-cell energy and repair, it remains unclear whether topical NAD+ in ordinary creams can penetrate the skin in sufficient amounts to produce meaningful anti-ageing effects.

Better-established ingredients, such as sunscreen, retinoids and niacinamide, currently have much stronger evidence for improving visible signs of skin ageing.

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NAD+ precursors as supplements

Because NAD+ itself is not thought to be absorbed efficiently when swallowed, much research has focused on NAD+ precursors. Precursors are compounds the body can convert into another substance. In this case, they are compounds the body can convert into NAD+. Two of the best known are nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR).

In animal studies, NAD+ precursors have produced promising results. Older mice given these compounds have shown improvements in energy metabolism, insulin sensitivity and aspects of physical function. Some studies have also reported improvements in healthspan and lifespan-related measures in animal models, although these findings vary by model and do not translate neatly into humans. These results have helped drive enormous commercial interest, but turning promising mouse studies into meaningful benefits for people has proved far harder.

Human clinical trials suggest that NMN and NR can raise NAD+ levels, or related markers of NAD+ activity, in blood and tissues. However, the strongest evidence is for changes in blood, while evidence for meaningful effects in specific tissues is still limited.

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Some small studies have reported possible benefits for metabolic health, including insulin sensitivity in specific groups. Others have explored potential effects on muscle mass, but recent reviews have not found convincing evidence that NMN or NR preserve muscle mass or function in older adults.

When researchers look at outcomes that matter more directly to everyday ageing, such as strength, cognition, frailty or biological age, the picture is much less clear. Biological age is a contested estimate of how old the body appears at a cellular or molecular level. One major problem is that ageing unfolds over a long period, while most supplement trials last only weeks or months.

Resveratrol

Resveratrol is another compound often promoted for anti-ageing, but it is different from NMN and NR. It is not an NAD+ precursor. It belongs to a group of natural plant chemicals called polyphenols and is found in red grapes, berries and peanuts.

In laboratory and animal studies, resveratrol has been associated with lower levels of inflammation and improved mitochondrial function, meaning better activity in the parts of cells that help produce energy.

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The difficulty is that resveratrol has poor oral bioavailability. This means much of what is swallowed is broken down or modified before it can reach tissues in the form and concentration used in laboratory experiments. This creates a large gap between what resveratrol can do in cells in a dish and what a supplement is likely to do in the human body. So far, human trials have not shown convincing evidence that resveratrol slows ageing, and findings on cardiovascular and anti-inflammatory benefits remain mixed.

Resveratrol may interact with some medications, especially anticoagulant and antiplatelet drugs, often described as blood-thinning medicines. High doses can also cause side effects such as gastrointestinal symptoms. Anyone taking regular medication, managing a chronic condition, pregnant or breastfeeding should seek medical advice before taking high-dose supplements.

So, are NAD+, NMN and resveratrol the elixir of youth? No. The key distinction is between biological plausibility and proven benefit. These compounds are not biologically implausible: they act on real pathways involved in energy production, stress responses and cellular maintenance. But affecting a pathway is not the same as slowing ageing in a person.

In humans, the evidence so far suggests possible benefits in limited contexts, but major questions remain about long-term safety, optimum doses and who is most likely to benefit. The science is plausible, but the marketing often turns “this affects a process associated with ageing” into “this supplement will keep you young”.

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For now, the best-supported ways to support healthy ageing remain far less glamorous: regular exercise, good sleep, a balanced diet, avoiding smoking, limiting alcohol and managing long-term health conditions. Supplements may eventually prove useful, but at present, the evidence for staying younger for longer is much stronger for everyday habits than for anti-ageing products.

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Emi Martinez suffered nightmare injury in warm-up before winning Europa League final | Football

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Emi Martinez suffered nightmare injury in warm-up before winning Europa League final | Football

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