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Caster Semenya calls out Olympics

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Caster Semenya calls out Olympics

Double Olympic champion runner Caster Semenya has announced that she will challenge the International Olympic Committee’s (IOC) new ban on intersex and trans athletes. She’s also encouraging fellow Olympians to join her in a class action lawsuit.

On Thursday 26 March, the IOC announced that it was reinstating mandatory sex testing for eligibility to compete in women’s athletics. It plans to require all participants to undergo an SRY test, which detects the presence of a Y-chromosome-linked gene.

Caster Semenya: ‘I was told I needed to have surgery’

Semenya has become a figurehead of the battle around the borderlines of women’s sport after facing years of highly public legal battles over her natural testosterone levels. In an article for the New York Times, she explained that:

In 2009, as I prepared to run in the Berlin World Championships, athletic authorities sent me for some medical testing. Because of my looks, there had been speculation from my fellow athletes, sports officials, the media and fans that I was not what I said I was.

I arrived at the medical appointment expecting to be checked for performance-enhancing drugs. Instead, at age 18, I had my first gynecological exam. Afterward, I learned that I had XY chromosomes, rather than the typically female XX pairing, and high levels of testosterone, produced by undescended testicles I didn’t know I had. In order to continue racing as a woman, I was told, I needed to have surgery to remove them.

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After Semenya refused to undergo the unnecessary operation, authorities instead required her to take medication to lower her testosterone. The medication caused extreme fatigue, nausea, headaches, and brain fog. When Semenya stopped taking it, she was barred from competing, and instead became a coach.

Despite having lived her entire life as a woman, the IOC’s new document refers to people like Semenya as “biological males”. It insists that this “does not and cannot change”.

‘It came as a failure’

As such, it’s unsurprising that Semenya has been a vocal critic of the IOC’s ruling, and its new president, Kirsty Coventry of Zimbabwe. On Sunday 29 March, at a press conference in Cape Town, Semenya said of Coventry that:

For me, personally, for her being a woman coming from Africa, knowing how African women or women in the global south are affected by that, of course, it causes harm.

Black and brown women have been targeted by a disproportionate level of arbitrary sex testing in sports.

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Semenya went on to criticise the IOC’s previous requirement for sex testing:

It came as a failure. And that’s why it was dropped.

For you as a woman, why will you be tested to prove that you fit? You know, it’s like now we need to prove that we are worthy as women to take part in sports. That’s a disrespect for women.

The IOC abandoned its previous requirement of blanket sex tests for women in 1999. The tests were of questionable scientific merit, and often caused severe identity crisis, social isolation, demeaning reactions from the public, depression, and suicide.

Following its U-turn, the IOC will now require girls to take the test from age 15 and up.

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‘It does not save women’s sport’

In an exclusive interview with Sky News, Semenya stated that:

I’m fighting for women’s dignity. Those who say, ‘I am not going to be tested to prove that I’m a woman’ … I will encourage them to do that to stop this nonsense.

As such, she also announced her plans to tackle the IOC in court:

I will encourage athletes to come together as a class action … because this does not make sense. It does not save women’s sport.

The interviewer questioned Semenya on the IOC’s new guidance. It states that there is a “10-12 per cent Male performance advantage” in running and swimming, and up to 100% in punching and lifting sports.

However, the document somehow failed to mention that intersex and trans athletes often reduce their testosterone. Just five years ago, the IOC held that this eliminated their potential advantage.

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Semenya replied:

Based on what? There’s no scientific proof about what has been said. It’s an ideology.

She’s right to question the IOC’s science, given that the Olympic body has failed to share it with the public. What we do know is that this latest ruling completely contradicts the IOC’s science from just five years ago, which stated that trans people “should not be deemed to have an unfair or disproportionate competitive advantage”.

The IOC’s ‘new science’ now happens to align with the views of Donald Trump. When he came to office, the far-right American president moved to ban trans athletes from all sport in the US. This is particularly convenient, given Los Angeles will host the next Olympic games.

Ideology over all

Semenya is also correct in her statement that this is an ideological battle. In the Guardian’s article on Semenya’s criticism of the IOC, it states that:

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The best-known DSD [difference of sex development] athlete of recent years is Semenya, who has male XY chromosomes.

Semenya doesn’t have ‘male XY chromosomes’. She has XY chromosomes – she hasn’t nicked them from some bloke; she’s a woman, who has lived her whole life as a woman. These are neutral statements that nobody – not even Semenya herself – started questioning until she started winning.

Across humanity, both sex and gender are a spectrum filled with countless variations. The belief that men have XY chromosomes and women have XX chromosomes is just that – a belief. It isn’t a fact – in fact, it’s demonstrably false, as in Semenya’s case.

We’re told that the distinction is natural, and therefore good and right. In fact, the distinction is so natural that we require women like Semenya (and countless intersex babies) to undergo unnecessary, often non-consensual surgeries and take medication in order to make them more ‘natural.’

Separating men and women into two distinct categories and insisting that they can never meet is a legal fiction. It relies on the perpetuation of intersexist and transphobic violence against anyone caught in the borderlands. Natural, universal distinctions don’t need police at their boundaries. 

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Featured image via the Canary

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Backrooms Director Admits He’s Already Got Ideas For A Sequel

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Director Kane Parsons with Backrooms actors Chiwetel Ejiofor and Renate Reinsve

The director of Backrooms has revealed he’s already got ideas for more films set within the film’s bizarre universe.

Released last week, Kane Parson’s critically-acclaimed new horror movie centres around the lonely owner of a struggling furniture shop, who stumbles upon an unsettling other dimension through the wall of his store’s basement.

As he progresses further into the seemingly limitless space, he becomes increasingly obsessed with what he discovers and how it relates to the world outside.

During a new interview with Variety published on Backrooms’ release date, its director teased: “Without a doubt, Backrooms has always been planned to be more of a series that goes outside the confines of this film.

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“If anything, I would say this is a bit of a foot in the door that would lead to more of a progression towards the true root of the narrative, which has been set up online for years. But a version that maintains accessibility and lets this be the way in.”

Director Kane Parsons with Backrooms actors Chiwetel Ejiofor and Renate Reinsve
Director Kane Parsons with Backrooms actors Chiwetel Ejiofor and Renate Reinsve

He continued: “For people who are into it, I’ve got a contract, and I got a hold at my end, and that means I am definitely not done with Backrooms.

“I’ve got very specific things that I’m working on, things are in the works right now that I am eager to be able to talk about, but, currently, it’s still in a secret mystery world.”

Backrooms’ origin story is a bit of an interesting one in itself.

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The idea stems from a 4chan post from back in 2019 showing an environment similar to the one seen in the Backrooms movie, which then became its own “creepypasta” (an online term for a widely-shared horror story that gains notoriety and viral fame by being copied and pasted around various corners of the internet) when someone came up with text to accompany it.

While Backrooms’ original “creepypasta” was shared anonymously, Kane Parsons began a YouTube series based on the idea in 2022, the success of which led to his new film.

He added to Variety that he has no intention of “leaving YouTube behind” now he’s crossed over into feature-length filmmaking.

“I immensely enjoy the work I’ve done there, and I feel creatively fulfilled by it in a way that’s proportional to what I’ve done with this film,” he insisted. “I personally think there’s merits, because there’s a lot of projects that I just could never do outside of YouTube, or outside of a more free-form internet multimedia container.

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“So I wouldn’t limit myself just to one spot, but I do think it’s a way of saying that I’ve got a bit of a good thing going right now that I want to utilise with the energy and positivity around this film.”

Backrooms is in cinemas now.

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Cenk Uygur banned by UK for criticising Israel, anti-genocide host says

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Cenk Uygur, TV host

Cenk Uygur, TV host

The Home Office has banned left-wing commentator and TV host, Cenk Uygur, from entering the UK, on Israel’s behalf. He is a vocal critic of pro-Israel influence over Western governments. Cenk Uygur has highlighted the irony of the UK ban over X. He said:

if I had said that the Israeli government controls the British government so thoroughly that they’ll ban someone from coming to the UK just for criticizing Israel, they would have said that was an antisemitic statement.

The commentator noted that he was banned not for any views or opinions he’s expressed about the UK.

Uygur argued that “Israel controls the American government,” largely because the pro-Israel lobby in the US channels significant financial support to members of Congress. He presented this as the main issue for Starmer’s government. While this is an overly simplistic and debatable political argument, it is not inherently a religious one. Nevertheless, some pro-Israel voices in the UK claim otherwise.

The UK banning Cenk Uygur for criticising Israel’s genocide in Gaza and US support isn’t just an attack on free speech, either. It also carries an antisemitic implication. This implication falsely equates criticism of genocidal war criminals with hatred of a whole religious group.

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Cenk Uygur had previously called for the US to assert independence from pro-Israel interests during an appearance on Piers Morgan‘s talk show. After the UK decided to ban Cenk Uygur, Morgan has defended his guest, emphasising that he was making political rather than religious points:

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Green Party leader Zack Polanski, has also called out the government’s cynical move. The Jewish politician lamented how the Labour government was:

doing everything possible to silence criticism of the Israeli government.

He called the ban of both Cenk Uygur and fellow Israel critic Hasan Piker “a really grim decision”:

It’s one thing for a government to challenge people spreading hatred of entire religious or ethnic communities. It’s another entirely when a government decides to limit political debate on behalf of a country currently committing genocide. And that’s exactly what has just happened.

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Featured image via the Young turks / YouTube 

By Ed Sykes

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HuffPost Headlines June 01, 2026.

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HuffPost Headlines June 01, 2026.

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This Obsession Alternative Ending Would Have Totally Changed The Film

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This Obsession Alternative Ending Would Have Totally Changed The Film

This article contains spoilers for Obsession.

As word of mouth continues to spread, Obsession remains one of the most talked-about films of the year right now.

The latest big-screen offering from former YouTuber Curry Barker centres around close friends Bear and Nikki, whose worlds are turned upside down when the former makes a wish for the latter to love him “more than anyone in the fucking world” – only for it to come true, with disastrous and tragic circumstances.

By the end of the film, almost all of the main characters are dead, aside from Nikki, whose realisation about what has transpired comes only after Bear has taken his own life and the wish’s hold is released.

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However, it turns out this wasn’t the original ending that Curry had in mind.

Speaking to Entertainment Weekly around the film’s release, the filmmaker revealed it had originally been his intention for Nikki to kill herself too, drawing comparisons between a Shakespearean tragedy.

“I was really obsessed with this Romeo and Juliet ending, actually,” he claimed, revealing that he was originally adamant that Nikki should die, and even filmed this conclusion to the film.

Curry recalled: “We had shot a ton of different versions of the official ending, the one that’s in the script, the one that I was excited about, and I was like, ‘Okay, we’ll do one ending where [Nikki] survives, but we’ll just do one take of it, and then we’ll move on’.”

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However, in the end, actor Inde Navarette’s “performance was so good” that everyone who saw the ending where Nikki survives convinced Curry that this was the one he should go for.

“I just remember my dad and multiple people around me being like, ‘Dude, I think it’s way more disturbing if she just survives this thing’,” he revealed. “I was like, ‘Ah, you’re right’. And so we switched it.”

Obsession has so far been a hit with critics and cinemagoers, with an enviable critical score of 96% on Rotten Tomatoes and 4.2 stars from fans on Letterboxd.

Curry has also addressed the possibility of another film set in Obsession’s in-universe, albeit with new characters, while Inde has made it clear she’d be up for playing Nikki again if the opportunity arose.

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Obsession is in cinemas now.

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Exclusive: Union Boss Slams Farage’s Claim That Reform Are ‘Party Of The Working Class’

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Union Boss Slams Farages Claim About Reforms Class Base

A trade union boss has dismissed Nigel Farage’s claim that Reform UK is now the party of the working class.

He spoke out after new polling showed that union members are now just as likely to vote Reform as they are Labour.

The Times reported that 28% of them would now back Farage’s party, the same proportion as back Labour.

It follows a remarkable turnaround in the fortunes of both parties since the general election in 2024.

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At that time, just 16% of trade union members backed Reform, while 48% supported Labour.

Reacting on X, Farage said: “Labour is no longer the party of the patriotic working class. That mantle now belongs to Reform.”

But speaking to HuffPost UK last month, Unite general secretary Sharon Graham pointed out that Farage’s voting record in the House of Commons flew in the face of his claim to speak for working people.

She said: “The reality is that Nigel Farage has shown no indication to me that he’s the voice of workers. He voted against the Employment Rights Act, for example.

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“He’s said that when he goes into the local authority areas he’s going to be looking at [cutting] local authority pensions. So to me, if your go-to lever in terms of what is happening in councils is to attack workers, then you can’t be the voice of workers. That is just the reality of it.”

Graham said she had “put Reform on notice” that Unite will fight any attempts by the party to attack the rights of public sector workers.

“We will not accept that in any way, shape or form,” she said.

“I’ve been asked would Unite work with Reform. I’m on record saying I’d dance with the devil if it was something that was important to my members. But the broader issue here is ‘is Reform the party of workers’? No, it isn’t.”

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She added: “I very often hear words about people backing workers, it’s very different when you’re asking them to do something about that.

“If Reform go after workers in local councils, then Unite will be going after Reform.”

However, Graham also accused Labour of “abandoning” the party’s traditional working class supporters.

She said: “The problem that Labour have is that they are supposed to be the voice of workers, and essentially workers feel abandoned by Labour.

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“The working class feels abandoned by Labour, and now the working class have abandoned Labour. The question is can Labour get that back?

Subscribe to Commons People, the podcast that makes politics easy. Every week, Kevin Schofield and Kate Nicholson unpack the week’s biggest stories to keep you informed. Join us for straightforward analysis of what’s going on at Westminster.

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Can I Bring A Fan Onto My Flight? Travel Expert Explains The Rules

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Can I Bring A Fan Onto My Flight? Travel Expert Explains The Rules

It’s bloody hot. It’s half-term. And for many, that means it’s holiday season.

However, 2026 fliers might want to check some details before arriving at their airports. It’s not just that multiple airlines have issued advice following new EES checks, or that some routes may have changed following ballooning jet fuel costs.

Recently, a flight was diverted after a passenger reported a charging power bank in another flier’s bag, too (we’ve written before about why that’s a problem, as well as how to tell if your portable chargers are compliant).

So what about other devices, like handheld electric fans?

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We thought we’d ask the experts.

Can I bring an electric fan onto my flight?

HuffPost UK asked Helen North, Head of Dangerous Goods at the UK Civil Aviation Authority, whether all handheld electric fans can come on board.

“Portable electric fans may contain lithium batteries, so they should be carried in the cabin, not packed in your checked bag,” she said.

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“Keeping battery-powered items with you will make your flight safer for you and the other passengers you’re flying with.”

Lithium batteries are the same kind of batteries that devices like smart bags and power banks use.

They’re not usually allowed in the hold of planes (i.e., checked luggage).

That’s because they can short-circuit and catch fire, which can be especially disastrous in an unattended baggage space.

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Generally, the Civil Aviation Authority said, lithium batteries should be carried as hand luggage.

And they added, “if carried as checked baggage, the devices must be completely switched off (not in sleep or hibernation mode) if the batteries exceed:

  1. for lithium metal batteries, a lithium content of 0.3 g per device; or
  2. for lithium-ion batteries, a Watt-hour rating of 2.7 Wh per device.”

Any other advice?

Yes. Most airlines won’t let you bring more than two power banks onto a plane, and you can’t use them to charge another device while you’re flying.

They generally aren’t allowed in the hold because of lithium battery limits.

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Additionally, lithium batteries over 100Wh and under 160Wh will need to be cleared by your specific airline (those over 160Wh can’t come on board).

If you can’t find this, you can work it out from the milliampere-hour (mAh), ampere-hour (Ah), and/or nominal voltage (V).

Once you find these, the UK Civil Aviation Authority said: “You can arrive at the number of watt-hours your battery provides if you know the battery’s nominal voltage (V) and capacity in ampere-hours (Ah) using this calculation: Ah x V = Wh”.

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Saudi must overcome challenges of the past at the 2026 World Cup

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Salman Alfaraj of Saudi Arabia scores a penalty for his team's first goal during the 2018 FIFA World Cup Russia group A match between Saudia Arabia and Egypt at Volgograd Arena on June 25, 2018 in Volgograd, Russia

Salman Alfaraj of Saudi Arabia scores a penalty for his team's first goal during the 2018 FIFA World Cup Russia group A match between Saudia Arabia and Egypt at Volgograd Arena on June 25, 2018 in Volgograd, Russia

When the Saudi national team takes to the pitch at the 2026 World Cup, they will carry a weighty legacy of both glory and anticipation.

In the same country that witnessed its greatest World Cup moments more than three decades ago, the Green Falcons return to reclaim a story that has remained unfinished since the summer of 1994. In 1994, Saudi entered the tournament for the first time and emerged having put their name on the map of world football.

Since that extraordinary American summer, generations have come and gone, and teams and managers have changed, but that achievement remains a solitary entry in the annals of Saudi football.

Today, as the World Cup returns to the US, the same question returns with it: will America once again be Saudi Arabia’s gateway to the knockout stages?

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Saudi: The newcomers who became a phenomenon

No one expected much from a team making its World Cup debut. However, the Saudi Arabia side at the 1994 World Cup refused to be just another number in the tournament.

In a group featuring the Netherlands, Belgium and Morocco, the Green Falcons managed to write one of the most inspiring stories in the history of Arab and Asian participation. The team secured a place in the Round of  16 with two historic victories, most notably their famous win over Belgium.

Thanks to a goal by Saeed Al-Owairan, he became an enduring icon in World Cup history.

The achievement was not limited to the results alone but also to the character the team displayed. A brave, confident side, capable of competing against opponents who surpassed them in experience and history. Even after their elimination by Sweden, Saudi Arabia left the tournament carrying the respect of the entire world.

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Since that day, the 1994 World Cup has become a constant reference point in any discussion of Saudi football at the World Cup.

Three decades in search of the elusive breakthrough

The Saudi national team took part in the 1998, 2002 and 2006 tournaments without managing to progress beyond the group stage, before missing out on the 2010 and 2014 editions. They then returned for Russia 2018 with a late victory over Egypt, but it was not enough to keep them in the tournament.

As for Qatar 2022, it seemed as though history was poised to write a new chapter. A historic victory over Argentina, who went on to become world champions, gave the Saudis a legitimate dream of qualification. But losses against Poland and Mexico brought the team back to square one.

This is where Saudi Arabia’s World Cup dilemma of recent decades lies: the ability to create a defining moment is there, but the ability to turn that moment into a lasting achievement has remained elusive.

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A group testing ambition and realism

The draw was not kind to Saudi Arabia for the 2026 World Cup. The presence of Spain, Uruguay and Cape Verde in the group presents the Saudi team with a series of varied challenges.

Spain represents a style that dictates the tempo through possession and technical quality, whilst Uruguay embody one of the world’s most resilient and fierce sides in major tournaments.

As for Cape Verde, they may lack the star quality of their rivals, but this match appears to be the most crucial in the qualification calculations, as it could prove to be the difference between staying in the competition and being eliminated.

Nevertheless, the difficulty of the group does not mean the task is impossible. In 1994, too, the odds were not in Saudi Arabia’s favour, but the team managed to turn the tables and secure their place among the qualifiers.

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Where can Saudi Arabia make the difference?

The clash against Spain looks the toughest from a technical standpoint. The Saudi team will need great tactical discipline and the ability to close down space and deny the opposition complete control of the game’s tempo.

Against Uruguay, the battle will be completely different. Physical intensity, one-on-one duels and second balls will dominate the match, making concentration and mental resilience crucial factors.

As for the clash with Cape Verde, it could be the match that decides the fate of the entire group. Such matches leave no room for hesitation as they often determine which teams will remain in the race and which will exit early.

The victory over Argentina at the 2022 World Cup in Qatar remains fresh in Saudis’ memories as one of the greatest triumphs in Arab football. The victory carries an important lesson as well being a source of pride.

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The World Cup does not reward the team that wins a single match but rather the team capable of maintaining its balance throughout the tournament. For this reason, Saudi Arabia in 2026 needs more than just a resounding surprise.

It needs consistency, the ability to manage difficult moments, and the capacity to come away from every match with the best possible outcome, be it three points, a single point, or even a defeat with limited damage.

Donis faces a different test

On the bench, Georgios Donis will face one of the biggest challenges of his coaching career.

His deep knowledge of Saudi football is a significant strength, but it will not be enough on its own in a tournament of the World Cup’s stature. What is required is not merely to prepare a competitive team, but to build a squad capable of handling shifting pressures, reading the big games, and capitalising on the opportunities afforded by the new format.

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Donis’ real task is to turn memories into a competitive project, not a psychological burden that haunts the players. The return to the US carries a symbolism that is hard to ignore. It was there that Saudi Arabia’s greatest World Cup dream was born, and it was there that the finest chapter in the history of the ‘Green’ team’s participation was written.

But modern football does not recognise memories alone. What happened in 1994 may inspire, but it does not confer any advantage on the pitch. Past achievements light the way, but they do not walk it on behalf of those who achieved them.

Featured image via Catherine Ivill/ Getty Images 

By Alaa Shamali

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Jill Biden dismisses Democrats’ infighting concerns: ‘Things are going to move forward’

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Jill Biden dismisses Democrats’ infighting concerns: ‘Things are going to move forward’

Former first lady Jill Biden waved away Democrats’ concerns that her new memoir is setting off a wave of backward-looking infighting, insisting that the party is moving on from the 2024 election.

“Democrats have a great future,” she said in an interview on Monday on NBC’s “Today,” when asked if she was “reopening old wounds” with her tour. “We’re looking forward to winning the midterms. Things are going to move forward. … And yes, we’re going to look back and learn from the mistakes we made.”

Jill Biden is on tour promoting her new memoir, which has become the latest headache for Democrats. Some Democrats privately say Jill Biden’s return to the public eye is a “distraction” that risks relitigating a painful election for the party when it should instead be focused on winning in the future.

In her book, she opens up about then-President Joe Biden’s disastrous, career-ending debate in 2024. She was “frightened” watching her husband on stage, and feared he was having a medical episode of sorts.

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Her confession hasn’t landed well with fellow Democrats and former White House aides, given her relentless defense of Joe Biden at the time.

“I had to lift him up [after the debate]. I’m his wife,” she told NBC. “I’m not going to get out on the stage there and say, ‘Joe, you really screwed that up.’”

The press tour comes as Democrats are still reeling from their long-awaited autopsy of the 2024 presidential election. Its botched, typo-ridden release failed to explain Democrats’ defeat — and skipped over the former president’s age — but did spark a fresh round of party infighting.

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How Many Wedding Guests Is Normal?

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How Many Wedding Guests Is Normal?

Congratulations are in order for singer Dua Lipa and actor Callum Turner, who tied the knot in Old Marylebone Town Hall over the weekend.

Per The Sun, the “intimate” ceremony involved just eight guests and was followed by a small dinner.

Speaking to HuffPost UK, Nikita Thorne, a wedding planning expert at Guides for Brides, said the Future Nostalgia singer’s low-key nuptials are part of a controversial “shift”.

Guest lists are getting shorter

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“Since Covid, we’ve definitely seen a shift towards smaller, more intentional weddings,” Thorne told us.

“During the pandemic, couples were forced to strip weddings back, and for many people, I think that encouraged them to focus more on what genuinely mattered to them… Chic city weddings, private ceremonies and smaller guest lists are now often viewed as aspirational and stylish rather than a compromise.”

In 2025, The Economist wrote, town hall weddings in London’s popular Old Marylebone and Islington venues jumped 29% and 51% respectively.

No matter the venue, the expert said, guest lists seem to be shrinking.

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“Currently, we are seeing a significant increase in couples only inviting those with whom they have a direct relationship, often leading to them excluding plus-ones, even when it’s a long-term partner of the guest invited,” Thorne shared.

“This is causing a lot of controversy, but from the couple’s point of view, [it] is understandable if they want the most stress-free wedding surrounded by those who know them well.”

How can I tell if my guest list is too big?

When I asked Thorne if she recommended an upper limit for wedding guests, she said it really depends on the couple.

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“Some couples genuinely love the atmosphere and energy of a big wedding. On one hand, larger weddings naturally come with more hosting responsibilities and cost,” she said.

But “smaller weddings can feel more pressured as each guest has more time to spend with you,” too.

Some couples like the combination of a low-key ceremony followed by a more buzzy party (as with Charli XCX, whose wedding was also a town hall do, Dua Lipa and Callum Turner are rumoured to be planning a huge Italian bash later on).

“Be intentional with your guest list,” Thorne said.

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“You want to feel relaxed, comfortable and genuinely happy with the people surrounding you on the day.”

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The Health Benefits Of Drinking Three Cups Of Coffee A Day

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The Health Benefits Of Drinking Three Cups Of Coffee A Day

If you think your morning cup of coffee is a “guilty habit,” you might want to think again.

Drinking up to about three or four cups of coffee a day has been linked to a longer life. Black coffee with no sugar in particular could help us live longer and age better. However, we aren’t definite about why that may be.

But a new paper published in Nutrients suggests researchers have found a clue: it seems to relate to a process involving protein NR4A1.

Why might coffee protect against the signs of ageing?

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The scientists wanted to look at the link between coffee and NR4A1 receptors, which are involved in a range of biological processes from tissue repair to metabolism.

NR4A1 is “involved in protecting the body from stress-induced damage,” Prof Dr Stephen Safe, who co-wrote the study, said.

“If you damage almost any tissue, NR4A1 responds to bring that damage down.. If you take that receptor away, the damage is worse.”

After looking closer at both coffee and this protein, they found that some parts of the caffeinated drink, including compounds like caffeic acid, seemed to bind to NR4A1 and change its activity level.

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“What we’re saying is that at least part of coffee’s health benefits may come through binding and activating this receptor,” Prof Dr Safe said.

They also saw that compounds in the coffee seemed to reduce cell damage and slow cancer cell growth in lab models, an effect that disappeared when NR4A1 was removed from cells.

This may explain the benefits of decaf coffee, too

The researchers found that caffeine might not actually be a major driver of these effects. Instead, other components seemed to matter more.

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“Caffeine binds the receptor, but it doesn’t do much in our models. The polyhydroxy and polyphenolic compounds are much more active,” said Dr Safe.

Still, the professor said, this is likely only one of many ways the beverage might help to protect us from the effects of ageing.

“There are many receptors and many mechanisms involved,” he shared.

But this finding “helps explain why coffee has the effects that it does,” and may show “there’s a mechanism behind it.”

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