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Reporting Indicates RFK Jr. Directly Intervened To Keep PA Deaths Off CDC Measles Report

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from the vanishing-act dept

The measles outbreak, that began in America nearly two years ago, has only increased in velocity. We recently talked about the deaths of two children in Pennsylvania who both died while infected with measles. I’m altering my language slightly here from that original post in which I described those children as having died of measles purely to acknowledge that there are some, including RFK Jr., who are trying to dispute the cause of those deaths. I’m comfortable stating that they died of measles, as are state officials in Pennsylvania, and as are competent local health professionals like Paul Offit. As explained in a previous post, the ruptured spleen that one newborn died from is an expected symptom of measles in newborns. Kennedy is trying to claim that the cause of death is the spleen, as though the measles infection played no role. That’s dumb, and he’s dumb and a liar, but here we are.

Well, when it comes to CDC reporting on the measles outbreak, the dedicated public page for tracking the numbers was last updated the day of this writing, September 4th. The data generally demonstrates just how shit of a job Kennedy and his crackerjack group of assclowns in government are doing in combating the outbreak. Keep in mind that Kennedy has publicly claimed that he’s doing an awesome job in all of this.

Cases? Up with 4 months left in the year.

Total number of hospitalizations? Up with 4 months left in the year.

Deaths? Well…

The page didn’t always read that way. For a brief moment several days ago, the death count simply stood at 2. Why? Because the CDC questioning state reporting on any statistic surrounding a medical outbreak like this is pretty much unheard of. It’s not how this works. And there was no explanation for why that change was made, other than it was done so on orders from newly confirmed CDC Director Erica Schwartz. Schwartz, you should recall, raised many eyebrows during her confirmation hearings when she was asked if she would refuse the influence of RFK Jr. if he wanted her to deviate from science and factual information, as he did with Susan Monarez on the topic of vaccines previously. She avoided the question entirely by stating she didn’t believe Trump or Kennedy would ever try to exert that kind of influence upon her.

Perhaps the most disturbing aspect of Schwartz’s testimony came when senators repeatedly asked her what she would do if (or when) she’s put in the same position as Monarez. Schwartz responded as if it hadn’t happened and would never happen. “I do not believe that the president or the secretary would ever do what you just mentioned,” she told Sen. Bernie Sanders (I-Vt.) at one point, prompting him to reply: “Really?”

We can be done with Schwartz entirely at this point. While she entered into her confirmation hearings with a good reputation and the cautious approval of all kinds of national medical groups, it’s clear that her failure to answer the above question is of consequence. That’s because new reporting indicates it was Kennedy himself who told her to keep those two Pennsylvania deaths off the CDC measles report.

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The Centers for Disease Control and Prevention is still secretly counting two measles deaths that were deleted from the agency’s public measles data—a deletion that occurred at the direct request of anti-vaccine Health Secretary Robert F. Kennedy Jr., according to two reports released today.

Early today, Reuters reported that Kennedy instructed new CDC director Erica Schwartz to delete the two deaths from the agency’s website. CDC staff had reportedly already reviewed information about the deaths and accepted the characterization that they were measles-related. Still, Schwartz deleted the deaths without objection, insiders told Reuters. According to previous reporting, the two deaths were added and then removed from the CDC’s website within hours on August 30.

Now, I will deign to note that Kennedy has disputed this report. But who really gives a shit, considering that Kennedy has demonstrated a willingness to both fudge the facts when it comes to medical data and that he’s been perfectly happy to lie directly to Congress. If he’ll lie to senators, there’s no doubt he’s willing to lie to you and the rest of the public. I personally have no doubt that this is yet another lie being told by someone with no conscience. And I’ll note that we typically call those people sociopaths.

As I mentioned above, this is not how CDC statistical reporting has traditionally worked. State health officials send the data in, having done their own due diligence, and the CDC reports on the data. In this case, CDC is suddenly disputing the data and claiming that the state hasn’t provided all the documentation needed to associate the deaths with measles. The state, unsurprisingly, is calling bullshit.

In an earlier statement to Ars Technica, HHS said that the two deaths in Pennsylvania “have not been confirmed based on the information currently available to CDC.” A spokesperson did not respond to a follow-up question about what information the CDC was lacking and/or awaiting from the state.

Pennsylvania’s state health department has said that it has provided the CDC with all the required information.

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I’m sure they have. Just as I’m sure that Kennedy is attempting to save face here by pulling this nonsense. Meanwhile, while Kennedy is primarily concerned with his own ego, I’ll remind our dear readers that there are two tiny fucking coffins in the ground from children who died as a result of Kennedy’s incompetence. He’s worried about him, not about you, your children, or your community.

Get his ass out of HHS. Get him out of government. The same goes for Schwartz and any other officials Kennedy has put in place in government. They all must go, as they are poisoned by Kennedy’s mere presence. Burn it all down and let’s start again.

Or else we’ll have more deaths, no matter how the government tries to hide them from view.

Filed Under: anti-vaxxers, cdc, hhs, measles, pennsylvania, rfk jr., vaccines

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Meta’s New AI Agent Wants to Get Personal With You

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This seems to be the year of AI agents, and Meta is diving into the game. The company on Tuesday announced a new agent program called Muse, which CEO Mark Zuckerberg describes as a “personal agent” that understands your habits and goals. It’s available now in the US.

Agentic AI is a type of generative AI based on a large language model where agents, or bots, are meant to take actions autonomously on your behalf. Meta’s Muse, for example, can do online shopping (with your permission), create documents, fill out forms and respond to emails.

Meta says that Muse is a more general-purpose agent, not limited to specific tasks like coding. (If you want agentic coding help, you can use Muse Code, also recently released by the company.) You have to give Muse permission to access your apps and data, which you can revoke at any time. Like a lot of agentic AI tools, the more info you give it, the more personalized your results will be.

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Muse runs “on its own dedicated computer in the cloud,” according to a Meta blog post, in what the company calls a “virtual machine.” The tool also has a separate Sentinel agent — you can think of it as a virtual traffic cop, giving Muse a red or green light before letting it out onto the internet to complete tasks.

Agentic AI can be risky. Over the summer, agents from Meta, OpenAI and Anthropic each slipped out of their testing environments and hacked outside websites, casting increased scrutiny on the potentially disastrous harm AI can do to our cybersecurity.

Meta’s vice president of Superintelligence Labs, Tarek Sheasha, said in a blog post: “The harness runs in its own isolated cell, it doesn’t see real credentials, and every interaction with the outside world runs through a Sentinel which the agent can’t override.”

Muse is available now on iOS and Android and on the muse.ai website. The company says it will be bringing the AI to its controversial smart glasses soon. According to Zuckerberg, it will be free for people to use “up to 100 million tokens per week” (one token is roughly equivalent to four characters). So unless you’re constantly running Muse on complex tasks, you should be able to use it for a while before running into a paywall.

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What Are The Major Changes Coming To Apple HomeKit In iOS 27?

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The Home app is getting some great AI upgrades, along with other cool tweaks.

iOS 27 is focused on features like Siri AI, along with making overall improvements. But there’s much more to this update, especially for those with HomeKit accessories. No, Apple isn’t bringing the revamped Siri to the HomePod just yet — though that might happen soon. Instead, HomeKit and the Home app are getting some great new features. 

Apple Intelligence is being further integrated into the Home app for smarter notifications. Plus, security camera footage will be much clearer now with 4K support. These features on their own may not seem like a big deal, but they definitely make the HomeKit experience better.

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HomeKit now integrates with Apple Intelligence

Perhaps the most notable change this year is deeper integration with Apple Intelligence. HomeKit has never really taken advantage of AI features until now, but that changes with iOS 27. The Home app can now summarize important notifications, such as when someone was seen at your door or when smoke is detected. This is especially useful for people who have multiple cameras and smart doorbells at home, as it should prevent you having your lock screen flooded with Home app notifications.

Speaking of cameras, they can now use AI to better detect faces or animals. Not only that, but the Home app combines footage from multiple cameras to show you the same event from a different angle. Say someone is moving around your house: the app will show you a sequence of footage of that person in every room equipped with a camera. 

The videos also come with a short AI-generated description, so you don’t have to spend minutes watching the whole clip to find out what happened. You can even search for events captured by your cameras, plus videos are now recorded in 4K.

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Apple TV owners have another reason to update to iOS 27, as the Home app can now update the software on all your Apple TVs at once. Plus, the app’s reliability has been improved overall, which is always appreciated.

New home accessories from Apple are coming soon

Some new releases haven’t been officially announced, but are likely coming soon. These are related to upcoming hardware, such as the rumored HomePad. If the rumors are true — and they probably are, based on internal code leaked by Apple itself — there are many new home accessories underway.

This includes a new generation of the HomePod mini, as well as a new product called the “HomePad.” As you might have guessed, this product is expected to combine the HomePod and the iPad into a single device. This would make it akin to Apple’s take on an Amazon Echo Show. It appears that this HomePad will have its own “Faces” gallery, just like an Apple Watch. The company has also been working on a tabletop robot, but this one probably won’t be ready for a while.

As for the features mentioned earlier, they’re all part of iOS 27. If you really want to try out the latest features ahead of time, you can always sign up for the Apple Beta Program. But since betas can be unstable, you should only install them on a spare device in case something goes wrong. 

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Alogic’s new 6K monitor hides a 12MP webcam that only pops up when you’re on a video call

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  • Alogic Clarity Touch 6K monitor packs 6016 by 3384 pixels into one massive display
  • The webcam retracts fully into the monitor when not in use
  • Thunderbolt 5 support is missing from this new flagship monitor

Alogic has upgraded its Clarity monitor range with a new 32-inch 6K model featuring an integrated 12MP webcam.

The company announced the display at IFA 2026 in Berlin, where it also showed several other new desktop products.

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5 Brands Revitalizing The Boombox For Modern Listeners

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We may receive a commission on purchases made from links.

When you think of boomboxes, you probably aren’t imagining exactly what you might call modern technology. Whether your main association is crowding around one with your arms full of CDs, sitting next to one while you fix your cassette tape with some clever pencil action, or standing out in the rain holding one over your head, the once-commonplace audio device doesn’t really scream “modernity.” But, despite its retro reputation, the humble boombox is actually joining the ranks of other retro gadgets making high-tech comebacks, along with flip phones, portable music players, and Game Boy-styled handheld game consoles.

The boombox resurgence isn’t being driven purely by one or two brands or novelty gadget lines, either. There’s actually a surprising number of modern boomboxes on the market now, produced by smaller boutique brands and bigger household names alike. Moreover, picking up a new boombox isn’t quite the same as grabbing an old, pre-loved one from a thrift store, yard sale, or eBay. Instead, these boomboxes have been updated with new features that help keep the tech feeling fresh and useful.

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Exactly how these companies have revitalized boomboxes varies a little both from brand to brand and from product to product, but there are a few common features shared across most modern boomboxes available on the market today. For example, for the most part, they tend to offer Bluetooth compatibility, alongside a couple of other input options like USB or microSD. But they still all hang onto that original boombox feel, based on how they look and what older features their manufacturers choose to include.

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Roxel

At first blush, Roxel’s retro boombox is almost indistinguishable from those of the 1980s and 1990s. However, the Camden Retro Boombox isn’t going to be among the old electronics you might find in your attic. It’s a full, modern, all-in-one audio system with Bluetooth 5.3 connectivity, DAB+/FM radio functionality, and an assortment of playback options including CD, USB, and microSD. 

Clearly, the Camden captures the retro look you might still want even from a nouveau boombox, alongside several features that were part and parcel with yesteryear’s audio gear. Namely, it comes with both a CD player and a tape deck, plus all of the knobs, buttons, and sliders you could want to get your hands on. On either side of the player’s crisp LCD display sit a 5.25-inch woofer and a 1.2-inch tweeter, with a total output of 20W RMS and 40W peak power. 

Alternatively, if you’re less into turning it up to 11 and prefer to tuck yourself away with a set of headphones, you can do that instead. It comes with a 3.5mm headphone jack, making it easy to listen privately and quietly — assuming you’re a part of the wired headphone renaissance, that is. Admittedly, that isn’t all that useful if you’re using the player’s Bluetooth integration or its other more up-to-date connection options like USB or microSD. After all, those could be better accessed through your computer or phone. Still, the headphone jack is a fun way of privately plugging into your CD or cassette collection.

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We Are Rewind

We Are Rewind is a French company that aims to reinvigorate older audio tech for modern sensibilities. Its offerings focus mostly on tangible, tactile physical media experiences, with the vast majority of the products revolving around tapes – a focus that’s perhaps no surprise, considering the recent resurgence of cassette tapes. Notable examples include handheld players à la Panasonic’s 1990s-era models, sleek acrylic tape racks, and of course, a revived boombox. 

Don’t be deceived by the boombox’s vintage stylings, though. Although We Are Rewind’s Blaster GB-001 retains a classic tape deck, it also comes with Bluetooth 5.4 functionality, catapulting the gadget comfortably into the modern era. Needless to say, that’s a solid option if you want to enjoy a little nostalgia by taking your boombox on the move, but don’t want to go so far down the retro rabbit hole that you wind up clanking around with a big bag of tapes just to do so. In addition to the box’s Bluetooth, it packs in four speakers, consisting of two tweeters for treble and two woofers to keep your basslines thick, alongside customizable sound controls.

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Something fun about the GB-001 is that it doubles up as an amplifier and recording device, meaning you can run an instrument or mic through it. Admittedly, at 104 watts of power, you won’t exactly be able to tear the house down with it, but it could prove to be a fun party trick for smaller spaces, or double up as a reasonable practice amp for use at home. Plus, you can still use it to record directly to any blank Type I or Type II tapes you still have lying around, if you’re feeling a little lo-fi.

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Bumpboxx

Bumpboxx has more than its fair share of modernized boomboxes and fun gadgets available, ranging from updated takes on pagers to stylized battery packs and themed Bluetooth speakers. The company is also behind several types of boomboxes, including the BB-777, Retroboom, and Freestyle Pro, alongside the Microboom: a tiny Bluetooth speaker cleverly disguised as a doll-sized boombox. Perhaps the most impressive of the company’s boombox-related products is the BB-777, which, as you may have guessed from the name, is a reimagining of the classic Sharp GF-777.

The BB-777 raised a whopping $7,133,869 during its Kickstarter campaign from keen and curious backers, and it isn’t all that difficult to see why. Besides the fact that it provides a relatively cheaper alternative to an original GF-777, which can now sell for four figures, it essentially offers the best of both worlds when it comes to newer and older technology. The BB-777 is designed to balance modern features, like True Wireless Stereo (TWS), Bluetooth, and versatile playback options, inside of a charming 1980s-styled chassis. Plus, it still holds onto a handful of physical media-oriented playback options, like a suction-load CD deck and a dual cassette deck, so the past doesn’t have to feel too far away.

Although these aren’t necessarily futuristic additions that completely reinvent the boombox, the BB-777 has a few other interesting features. The box includes six speakers: two 6.25-inch coaxial loudspeakers, two horn tweeters, and a pair of 6.25-inch super woofers with independent channel gain controls for loud, clearly defined audio, in addition to a fan-cooled amplifier and a suite of controls for fine-tuning your master volume, treble, bass, and balance. 

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Aiwa

On an aesthetic level, Aiwa’s boomboxes definitely look just like the kind of retro tech you might expect to only be able to find on a particularly lucky day at a garage sale. Don’t take how they look too much at face value, though; these portable stereos hide modern functionality underneath that nostalgic exterior. The Backtrack and Backtrack Junior models can both handle Bluetooth, AM and FM radio via analog tuning, and USB and SD card playback, while still including a classic cassette player and some direct recording options. You won’t find any DAB options here, so they might not be the best option if you find yourself tuning into digital radio regularly, but both types of Backtrack still offer a refreshing take on boomboxes for the modern day.

The full-sized Aiwa Backtrack also comes with the addition of a clear CD player, next to the boombox’s tape deck, allowing you to watch through the window as your selected album or single spins. You won’t find that functionality in the smaller Backtrack Junior, which instead shifts the focus to cassette, radio, and Bluetooth streaming. Similarly, the smaller model has a lower output, at 30W compared to the full Backtrack’s 40W. But that’s a trade-off you might be willing to take if you’re planning on taking your boombox out with you, since the Junior is also almost half the weight of its larger companion, with a weight of around 8.5 pounds.

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Philips

Philips is no stranger to the boombox game; the company was responsible for all kinds of now-retro portable playback devices that you may or may not remember from the recent past. Not every one of Philips’ boomboxes is like the bulky Super Tandems of the 1980s, though. Some of them offer newer features, like Bluetooth 6 streaming, DAB+ radio tuning, and even sleep timers.

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The CD Soundmachine range is a nostalgic sight if your main association with boomboxes is portable but cumbersome CD players from Y2K. They don’t look dissimilar at all — but thankfully, they do offer a few more options when it comes to deciding how to listen to your music than they did back in the day. That includes the previously mentioned Bluetooth and DAB support, as well as multi-source CD players, USB options, audio-in ports, and built-in cassette players. Besides the wide assortment of inputs, models like the AZB798T/12 come with built-in digital sound control presets, dynamic bass boost, and a bass reflex speaker system designed to harness low frequencies to minimize distortion while amplifying your music’s bass.

Much like the AZB798T/12, other recent Philips boomboxes like the TAZ2500/10 also come with Bluetooth and a selection of playback options like a top-loading CD player, front-loading cassette player, radio, and Type-A USB inputs. In terms of its radio capabilities, it offers both FM and DAB, with a digital tuner, smart scan, and up to 40 programmable presets: 20 for FM, 20 for DAB. Admittedly, it’s not the most powerful stereo you’ll ever find — it runs on two 2.5-inch speakers with a maximum output of 6W of power — but it does walk the line between retro boomboxes and modern audio needs nicely.

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How we chose which brands to highlight

We were careful not to just pick any old new boomboxes, so to speak. Instead, we made sure to look carefully for brands making boomboxes that integrated newer features and functionality in one way or another, rather than any companies that just appeared to continue manufacturing more old-school or simplistic boomboxes. To be more specific, that means we focused on devices that offered features like Bluetooth, USB connectivity, or other options along those lines. We didn’t want to include any boomboxes that just rehashed older models and functions without putting a modern twist on them. 

Traditionally, boomboxes tended to be portable sound systems with at least two built-in speakers and an integrated cassette deck, CD player, radio, or some combination of the three. With that in mind, we wanted to make sure we highlighted devices that kept some of those features alongside any modern additions, so you could retain that retro feeling by enjoying your physical media collection through your device. That way, we could make sure we weren’t just picking out Bluetooth speakers. That’s why we didn’t include JBL’s Boombox line or Soundcore’s Boom line, for instance, since both effectively work as portable Bluetooth speakers without other playback options.

While this is perhaps a given, we also made sure that any brands highlighted had boomboxes that were currently for sale, without having to turn to the secondhand market to buy them. If the product had been discontinued, we didn’t include it. And we also made sure to look out for boomboxes with generally positive ratings either among users or in professional reviews.

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Americans are turning against AI data centers as local fears over water, power costs, and land use keep growing nationwide

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  • 69% of Americans oppose AI data centers near their communities, a national poll finds
  • Public support for nearby AI data centers has fallen sharply since 2025
  • Only 4% strongly support new data centers in their communities today

American resistance to AI data centers has intensified sharply over the past year, several national surveys released in 2026 have found.

A new Decision Desk poll conducted by SurveyMonkey found that over two-thirds (69%) of respondents oppose construction of these facilities near their homes.

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‘100% real, no AI’: Watch video from Code.org founder Hadi Partovi’s Viking-inspired wedding

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Hadi Partovi, left and Becca Oystila during their wedding in a recreated/historic Viking village in Sweden. (Tommy Agriodimas Photo)

Maybe Hadi Partovi could use his sword or hammer to slay AI slop.

The co-founder of CodeAI, the computer science education platform that rebranded from Code.org earlier this year, is sharing video and images from his summer wedding, and it’s “100% real, no AI,” he says in a LinkedIn post.

It’s a smart disclaimer to add on social media, because the Viking-themed wedding to Becca Oystila appears unbelievable enough to be considered AI-generated — especially in an age where every other thing we scroll past is presumably touched by the tech.

Partovi told GeekWire it’s a statement about both AI’s advances and the work of Booka, the marketplace of beauty and events professionals started by Oystila.

“AI has gotten so good that people can hardly tell the difference from reality,” Partovi said via email. “And meanwhile, the Booka team delivers cinema-quality looks, which is why they have been chosen by Billboard, Soho House, and the Gold Gala as the beauty partner of choice for events.”

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To build out the July nuptials in Oystila’s native Sweden, the couple transformed the historic island of Birka — home to the remains of an authentic Viking settlement — into a fully functioning village, circa 826 A.D., according to The Information.

Partovi said the setup featured 200 “villagers” acting as merchants, armorers, goat herders, and a blacksmith, alongside Swedish Viking experts and actors from Netflix’s “The Last Kingdom.” Guests were given custom hand-aged gold and silver coins — which Partovi personally aged himself — to spend on period attire, weapons, or jewelry throughout the island.

“Becca deserves the credit for suggesting a Viking theme,” Partovi said. “And once she said that, the rest of the story wrote itself. Of course the longships and the battle were my idea.”

To keep the immersive experience intact, the couple enforced a strict no-phones policy once guests stepped onto the island, which is a UNESCO World Heritage Site.

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“Our goal was to make it the most authentic / immersive Viking experience created in history, and so the reason we had a phone library is because the Vikings didn’t have phones,” Partovi said. “We requested guests leave behind anything modern other than prescription glasses.”

Guests who didn’t dress authentically were provided alternate clothes. Professionals booked through Booka provided appropriate hair-braiding and face-painting. Some behind-the-scenes footage made this Instagram video.

When guests handed their phone in at the phone library, they received a Viking horn for drinking and a pouch of currency for use in the village. Partovi said even the few cameras on site were disguised for the sake of authenticity.

The guest list included prominent tech founders, executives, and venture capitalists, including Partovi’s twin brother and Neo CEO Ali Partovi; Rover co-founder Aaron Easterly; Sequoia Capital’s Alfred Lin; investor and former Snapchat executive Emily White; and Uber CEO Dara Khosrowshahi (Partovi’s cousin).

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Hadi Partovi and Becca Oystila during their traditional Persian wedding ceremony in Stockholm, Sweden. (Tommy Agriodimas Photo)

Partovi and Oystila started dating in April 2024 and got engaged in August 2025.

Oystila is founder and CEO of Booka, a Los Angeles-based beauty platform that connects clients with vetted, top beauty professionals and provides them with tools to manage and grow their businesses. Oystila said the 2-year-old startup is now launching nationwide and bringing its events concept and corporate events to the public across the country.

The Viking wedding wasn’t the only event that weekend in July. A second, traditional Persian ceremony was held in the Hall of Mirrors at the Stockholm Grand Hotel.

“That ceremony was followed by a reception in the large Winter Garden decorated in the style of the ancient Persian capital of Persepolis, transitioning to the architecture from Isfahan and Shiraz, mixed with peacocks, fountains, and fires to celebrate Hadi’s Persian culture,” Oystila wrote on Instagram.

Partovi, who lives in Bellevue, Wash., founded Code.org in 2013 alongside his brother. Its mission is to expand computer science education to K-12 students, and in June the Seattle-based nonprofit announced its name change and that AI was replacing coding as the primary focus. Partovi is also CEO of Payam Music, a Bothell, Wash.-based piano school that he planned to expand nationally.

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Asked whether he was considering keeping the braided mohawk hairstyle from his Viking look, which also included a skull “tattoo,” Partovi laughed and said no.

“My blue contact lenses and mohawk were for the day only,” he said. “I grew my beard out for six months for this!”

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‘It’s not unlike what they’re using at their own house for video games’: US Army budgets $465 million for Group 3 Killer anti-drone laser which uses Xbox controller

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  • The LOCUST X3 laser is developed by AeroVironment, Inc.
  • It is designed as a “group 3 killer” – meaning it is intended to tackle particularly dangerous drones
  • The Xbox controller makes the LOCUST X3 laser simpler to target

A new US Army contract worth around $465 million has been awarded to AeroVironment, Inc. for its LOCUST X3 anti-drone weapon, a 30-kilowatt laser that can be mounted on military vehicles.

Designed to take down mid-sized attack drones, the LOCUST X3 can specifically handle what the Department of Defense refers to as “Group 3” – unmanned aerial vehicles weighing 1,350 pounds and capable of lifting 125 pound payloads over a distance of 8 miles.

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Ukrainian drones hunted American armor across Germany, forcing Blackhawk troops to rethink how they fight from the ground

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  • Ukrainian drones forced American soldiers to rethink movement, concealment, and battlefield survival
  • Blackhawk troops changed their tactics after persistent aerial surveillance exposed their movements
  • American armored vehicles suffered losses despite attempts to conceal them from drones

A 10-day US Army combat training exercise in Germany has drawn attention after reports claimed Ukrainian drones overwhelmed an American mechanized company during the drill.

At the center of it is Blackhawk Company, part of the 2nd Battalion, 7th Cavalry Regiment, which spent the ten days training at a range in Hohenfels.

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Google DeepMind’s AlphaGenome Atlas Places a Score on Every Possible DNA Letter Change

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Google DeepMind AlphaGenome Atlas Human DNA Map
Google DeepMind opened AlphaGenome Atlas on September 8, 2026, as a free lookup table of predicted effects for every possible single-letter swap in human DNA. That catalog covers about nine billion single-nucleotide variants, plus more than one hundred million short insertions and deletions already seen in people. Anyone doing academic research can type a variant into a website and read the forecasts without writing code or running the original model.



Human DNA is 3 billion letters long, with just 2% of those characters actually coding for proteins, while the remaining 98% functions as a control center, determining when and where genes come to life. The control center contains the majority of variations associated with characteristics and diseases. Unfortunately, testing all conceivable one-letter alterations in a lab is simply impossible. Fortunately, Atlas has already done the tough job and crunched the statistics for us, saving the results in a database that is more than 30 times larger than the AlphaFold protein database, with a one petabyte collection that is just enormous in size.


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AlphaGenome, the AI model that powers that catalog, made its debut in June 2025, and DeepMind has since aimed it at every single location in the genome to obtain its outputs. Atlas delivers thousands of comprehensive molecular projections for each variant across hundreds of human and animal cells and tissues, including gene activity, chromatin accessibility, RNA splicing, and all other processes. These detailed forecasts are then condensed into one all-important AVI score, a single ranking that measures how much of an impact you can expect, and this score is so good that it even outperforms the AlphaMissense protein-altering changes, and it’s not limited to just coding DNA; it also works well with non-coding DNA. The AVI score now outperforms the competitors in terms of pathogenicity and rare-disease benchmarks.


What’s truly intriguing is that feature attributions break down the AVI score into bite-sized parts, allowing researchers to determine whether the outcome was driven by splicing, conservation, or DNA accessibility. If you’re inquisitive about what’s going on behind the scenes, you can search through a database of over 2,500 short DNA sequences known as motifs, which are the regulatory components that really get things moving.

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Recently, some Broad Institute researchers used the AVI scores to find a DNM1 variant that was a prime suspect in a severe form of epilepsy. Atlas predicted that the letter change would create a false splice site that would stretch the protein, and experimental screens later confirmed the prediction. If that wasn’t impressive enough, they discovered that grouping rare variants by predicted molecular effect yielded 22% more non-coding associations than previous methods, with these links including regulatory changes that affect PLA2G7, a protein associated with aging, and EGLN1, a sensor used by cells to detect oxygen. If you focus only on the top 1% of non-coding variants that have the most impact, you can identify 19 genomic areas that are all associated with body mass index.

Google DeepMind AlphaGenome Atlas Human DNA Map
When working on non-commercial projects, researchers can use Atlas via a web portal and an API; commercial use is planned for Google Cloud; however, keep in mind that Atlas is a research tool, not a diagnostic tool, and has received no clinical approval. This implies that any predictions you make will need to be validated in the laboratory. Even then, Atlas has some limitations because it only looks at around a million letters around each variant, so distant regulatory switches may be missed, and many disorders require multiple variants operating together rather than just one letter change. Nonetheless, the catalog allows rare-disease teams to rate candidates more quickly, as well as population geneticists to group faint signals that were previously missed in the noise.
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Layer GEN-300B Brings Single-Ended 300B Power to Headphone Listening for $1,499

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A 300B amplifier delivering single-digit or low double-digit power is hardly unusual. Doing it for $1,499 while also providing a transformer-coupled headphone output, 4- and 8-ohm speaker taps, custom transformers and Cardas internal wiring is a much more interesting proposition.

That is what makes the Layer Audio Design GEN-300B worth a closer look after CanJam SoCal 2026. It is a single-ended Class A integrated amplifier designed to serve both headphone listeners and owners of suitably efficient loudspeakers, without wandering into the five-figure territory that has become increasingly common for ambitious 300B designs.

Who Is Layer Audio Design?

Layer Audio Design is a small direct-sales audio company with a very compact product catalog. Its current lineup includes the GEN-300B, a GEN-2A3 integrated amplifier, the Henry Audio DA256 DAC and several accessories, while the company describes its design philosophy as a combination of measurement, materials research, vibration control and extended listening. 

There is not a long corporate history or decades-deep back catalog to lean on here, which matters when comparing Layer with established tube-amplifier manufacturers. The GEN-300B therefore has to make its case almost entirely on engineering, features and price, and that is where things become more interesting.

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What Is the GEN-300B?

The GEN-300B uses a fully discrete, all-tube signal path built around two 6N8P driver tubes, two 300B output tubes and one 5AR4 rectifier. Layer operates the output stage single-ended in pure Class A and rates the amplifier at 10 watts per channel into 8 ohms, with separate 4- and 8-ohm speaker connections. 

Ten watts clearly places some limits on speaker choice. The GEN-300B is intended for high-efficiency loudspeakers rather than insensitive floorstanders with difficult impedance curves, but that is hardly unusual for a single-ended 300B design. The more distinctive part of the package is what Layer has done for headphone users.

Rather than installing a separate solid-state headphone stage, the front headphone output is tube-driven and transformer-coupled from the main amplifier circuit. In other words, headphone listeners are not buying a 300B speaker amplifier with an unrelated headphone circuit tacked onto the front panel. 

Inside the GEN-300B

Layer specifies custom-wound Japanese transformers, Amtrans film capacitors and Cardas internal wiring through the signal and power paths. The company notes that the Amtrans capacitors come from the same component series used in Audio-Technica’s NARUKAMI amplifier, although sharing a capacitor family obviously does not make the two amplifiers equivalent designs. 

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Connectivity remains deliberately simple. The amplifier provides an RCA line-level input and a direct power-amplifier input for use with an external preamplifier, while Bluetooth is available as an option with Layer stating that the wireless module is electrically isolated from the analog circuitry. There is no built-in DAC or network streaming platform, so this remains an analog integrated amplifier first. 

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Layer Audio Design GEN-300B Specifications

Specification GEN-300B
Amplifier topology Single-ended pure Class A
Output power 10W/channel into 8 ohms
Output tubes 2 x 300B
Driver tubes 2 x 6N8P
Rectifier 1 x 5AR4
Inputs RCA line level, direct power amp
Optional input Bluetooth
Speaker outputs 4 ohms / 8 ohms
Headphone output Tube driven, transformer coupled
Internal wiring Cardas
Dimensions 13.19 x 8.27 x 10.43 inches
Weight 36 lbs / 16 kg

There are still some meaningful gaps in the published specifications. Layer does not currently list frequency response, THD, signal-to-noise ratio, headphone output power, headphone output impedance or input sensitivity, all of which would be useful when matching the GEN-300B to a broader range of headphones.

There is also a small inconsistency in Layer’s own documentation. The September production page lists the amplifier at 40 pounds, while the December preorder page lists 36 pounds with the same chassis dimensions, so I would wait for Layer to clarify the final weight before treating either figure as definitive. 

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What About Difficult Headphones?

Layer says the standard front-panel headphone output was designed around safe operation and broad compatibility rather than maximum output into the most demanding planar-magnetic headphones. The company subsequently developed the COPULA, a speaker-tap-to-4-pin-XLR adapter that connects directly to the GEN-300B’s binding posts and provides access to considerably more of the amplifier’s available output. 

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That solution is aimed at unusually inefficient headphones rather than conventional models or IEMs. Layer specifically warns against treating the speaker taps as a universal headphone output, which is sensible advice when the source on the other end is capable of delivering several watts.

Why Is It Unique?

None of the individual ingredients are revolutionary. Single-ended 300B amplifiers have existed for decades, transformer-coupled headphone outputs are well established, and 8 to 10 watts per channel is familiar territory for this topology.

What is unusual is getting all of those elements in one chassis for $1,499. Once custom output transformers, tube rectification, speaker taps and a serious headphone implementation enter the equation, 300B amplifiers usually become expensive rather quickly.

Layer’s relatively low pricing makes the established alternatives particularly revealing. For example, Woo Audio’s WA5 (2nd gen) is priced considerably higher at $6,499, while Feliks Audio Eos reaches nearly $14,000.

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Price & Availability

Layer Audio Design’s website lists pricing from $1,499 to $1,939. Bluetooth, finishes, headphone-output configuration and optional Cuprum isolation feet can alter the final price depending on the chosen configuration. However, a BATCHDEC26 coupon code currently takes $150 off the regular price.

Ultimately, pricing is likely to be the GEN-300B’s biggest advantage and its biggest question mark. Custom transformers, tube rectification, Cardas wiring and a transformer-coupled headphone output are not the ingredients one normally associates with a 300B amplifier at its price point. So long-term reliability, consistency between production batches and support will matter every bit as much as the parts list.

The Bottom Line

The Layer Audio Design GEN-300B is not interesting because it changes what a 300B amplifier can do. It is interesting because Layer is offering a legitimate single-ended Class A design with 10 watts per channel, speaker outputs and a proper tube-driven headphone connection at a price well below most established alternatives.

There are still technical questions that need answers, particularly around headphone output, distortion and the conflicting published weight figures. Layer also lacks the long track record of Woo Audio, Cayin or Feliks Audio, which is something buyers should consider before treating an aggressive introductory price as the only criterion.

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But as one of the more unexpected products to emerge from CanJam SoCal 2026, the GEN-300B has a very clear reason to exist. At $1,499, it makes the economics of serious 300B amplification considerably harder to ignore.

For more information: layeraudiodesign.com

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