Connect with us
DAPA Banner
DAPA Coin
DAPA
COIN PAYMENT ASSET
PRIVACY · BLOCKDAG · HOMOMORPHIC ENCRYPTION · RUST
ElGamal Encrypted MINE DAPA
🚫 GENESIS SOLD OUT
DAPAPAY COMING

Business

Natera, Inc. (NTRA) Presents at Goldman Sachs 47th Annual Global Healthcare Conference 2026 Transcript

Published

on

OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript

Natera, Inc. (NTRA) Goldman Sachs 47th Annual Global Healthcare Conference 2026 June 8, 2026 9:20 AM EDT

Company Participants

Mike Brophy – Chief Financial Officer

Conference Call Participants

Advertisement

Elizabeth Koslosky – Goldman Sachs Group, Inc., Research Division

Presentation

Elizabeth Koslosky
Goldman Sachs Group, Inc., Research Division

Advertisement

All right. Thank you. Well, good morning, everyone. I’m Evie Koslosky, the Life Science Tools and Diagnostics Analyst here at Goldman Sachs. And I’m joined here today by Mike Brophy, CFO of Natera.

Mike Brophy
Chief Financial Officer

Good morning. Thanks for having me.

Advertisement

Question-and-Answer Session

Elizabeth Koslosky
Goldman Sachs Group, Inc., Research Division

Advertisement

Of course. So I guess just to start things off, you came off a really strong Q1. You cleared the 1 million unit milestone for the first time in a single quarter, raised full year revenue guide. Maybe walk us through a high level what you saw in the quarter and then how things have changed since then?

Mike Brophy
Chief Financial Officer

Yes. Well, we had a great quarter. I mean, we had another record Signatera volume growth quarter. We had an absolutely massive women’s health quarter as a record on a number of different levels just in terms of volumes. Realized pricing was outstanding across the board, COGS per unit was actually outstanding across the board, if you look at the specific unit economics and the COGS per test that we delivered, had a very strong set of data that we just released at ASCO, I guess, last weekend, circa last weekend, that was very encouraging. So we’re on a fantastic trajectory here.

Advertisement

Looking into the rest of the year, we significantly bumped the revenue guide. We bumped the gross margin guide. We even bumped the R&D guide this year, which I viewed as a positive because what that meant was that

Advertisement
Continue Reading
Click to comment

You must be logged in to post a comment Login

Leave a Reply

Business

Angel One settles Sebi proceedings over lapses in monitoring authorised persons, pays Rs 4.28 crore

Published

on

Angel One settles Sebi proceedings over lapses in monitoring authorised persons, pays Rs 4.28 crore
Brokerage firm Angel One has settled adjudication and enquiry proceedings initiated by capital markets regulator Sebi after paying a settlement amount of Rs 4.28 crore, according to a settlement order issued by the regulator on Monday.

The proceedings related to alleged lapses by the company in monitoring and supervising the activities of two authorised persons (APs), Deepankar Barman and Nadella Srinivas Rao.

Sebi had issued separate show-cause notices in May 2025 under adjudication and intermediary regulations, alleging that Angel One failed to adequately identify and act on violations committed by the authorised persons.

According to the order, SEBI alleged that Angel One failed to detect unauthorised fund collection activities, did not conduct proper due diligence during inspections, and failed to take appropriate action despite disproportionate trading patterns by the authorised persons.

Advertisement

The regulator also alleged that the brokerage did not adequately scrutinise unauthorised social media activities by one of the authorised persons, including alleged promises of assured returns, unauthorised portfolio management activities and use of Angel One’s brand name and logo.


In the case of Nadella Srinivas Rao, SEBI alleged that Angel One failed to conduct inspections despite large fund collections and disproportionate trading activity. The regulator also flagged instances where orders were allegedly placed for multiple clients through the same IP and MAC addresses.
Sebi further alleged that both authorised persons were trading through other stock brokers, which the company failed to identify.Pending the proceedings, Angel One filed settlement applications in 2025 without admitting or denying the findings.

Following discussions with Sebi’s Internal Committee, the company agreed to pay Rs 4.28 crore as settlement charges. The proposal was subsequently approved by Sebi’s High Powered Advisory Committee and a panel of Whole Time Members.

The brokerage remitted the settlement amount on May 22, 2026. As a result, the adjudication and enquiry proceedings have been disposed of under the Sebi Settlement Proceedings Regulations.

Advertisement
Continue Reading

Business

ADM adds to plant-protein ingredient portfolio

Published

on

ADM adds to plant-protein ingredient portfolio

Company launches eight soy and pea protein-based solutions.

Continue Reading

Business

Plans to replace empty hotel with four-storey apartment block

Published

on

Business Live

Scheme aims to transform ‘dated and underused hotel site’

The new build plans for the former Henderson Hotel at 1 Wimbourne Place, Blackpool

The new build plans for the former Henderson Hotel at 1 Wimbourne Place(Image: Future PD Ltd)

Proposals to demolish an empty hotel on South Shore seafront and replace it with 15 self-contained flats have been lodged with Blackpool planners.

Advertisement

Planning documents show that 33 percent of the apartments (a total of five) will provide affordable housing, if the scheme gets the go ahead.

The application is for the erection of a four storey building comprising 15 self-contained permanent apartments, following demolition of the former Henderson Hotel at 1 Wimbourne Place, a site close to Blackpool Pleasure Beach Resort.

The Henderson Hotel was one of three adjoining hotels being offered for sale early in 2025 at £1.9m as part of a potential redevelopment project.

The site comprised three buildings – the Waldorf Hotel, the Kimberley Hotel and the Henderson Hotel – which required demolition before development takes place.

Advertisement

However, the current application involves the Henderson Hotel only, with no reference made to the other two properties.

A Design and Access Statement by consultants Future Planning and Development Ltd, has been submitted on behalf of the un-named applicants in supporting a Full Planning Application for the scheme.

The statement says that the initial proposals were to provide student accommodation in a new building with some 40 rooms, but Blackpool Council advised the applicants that the scheme would not be supported.

This was because the site was specifically designated for either permanent residential or holiday accommodation, and furthermore, the site was deemed too far away from the new Multiversity to offer easy access for all students.

Advertisement

The council also indicated that because the existing Henderson Hotel was considered visually attractive, “any replacement must show why reuse is not possible.”

Explaining the new need for a new building, the statement says of the current property: “The narrow circulation spaces, rigid structural layout, thin partitions, and outdated configuration present significant and inherent barriers to successful conversion or modernisation.

“Achieving a modern, building regulations compliant layout within the existing envelope would likely require extensive intervention, making comprehensive refurbishment or reuse highly impractical and economically unviable.”

The statement adds: “The vision for the redevelopment of 1 Wimbourne Place is to transform a dated and under used hotel site into a high quality, attractive and inclusive residential environment that makes a positive contribution to the local area.

Advertisement

“The proposal seeks to deliver much needed homes including affordable housing in a sustainable and accessible location close to the seafront and local services.

“It seeks to enhance the appearance and vitality of the streetscape, creating a building that sits comfortably within its setting and reflects the established character of South Shore.

“The proposal aims to support Blackpool Council’s regeneration objectives, providing new housing on brownfield land and contributing to local economic and social wellbeing.

“Overall, the development aims to create a place that residents can be proud to call home. A modern, efficient and well designed housing scheme that aligns with the town’s wider ambitions for sustainable growth.”

Advertisement
Continue Reading

Business

Fox Corporation to acquire Roku for $22 billion in cash and stock deal

Published

on

Fox Corporation to acquire Roku for $22 billion in cash and stock deal

In a move to capture the dual market forces of live broadcast television and digital streaming, Fox Corporation on Monday announced it is acquiring Roku, Inc. for $160.00 per share in a deal valued at an enterprise value of $22 billion. 

The combination pairs FOX’s live entertainment, news and sports portfolios — including The Tubi service, the NFL, MLB and FOX News Media — with the top television streaming platform in the U.S. by hours streamed, accelerating the company’s expansion into connected TV advertising.

Advertisement

“This is a defining moment for FOX, and a natural extension of the deliberate and focused strategy we have been executing for nearly a decade,” Fox Corporation Executive Chair and CEO Lachlan Murdoch said. “Today, we take the next step: bringing together the most valuable live content portfolio in video consumption with the preeminent streaming platform through which America watches it.”

WARNER BROS DISCOVERY SHAREHOLDERS APPROVE PARAMOUNT SKYDANCE DEAL

“We are executing this acquisition from a position of financial strength — maintaining our investment grade balance sheet while providing our shareholders with an uninterrupted return of capital program in the form of share buybacks and dividends,” Murdoch continued. “Roku pioneered streaming TV and scaled it into a leading CTV platform. Together, we intend to lead its next chapter.”

Roku logo next to FOX logo

Fox Corporation announced Monday, June 15, 2026, that it would be acquiring TV maker Roku for $22 billion. (Getty Images)

The transaction positions the combined company as the third-largest player in U.S. television by share of viewing. Currently, Roku is in over 100 million global streaming households, which includes more than half of all U.S. broadband households.

Advertisement

Unanimously approved by the Boards of Directors of both companies, FOX is buying the company using a mix of cash and its own stock. Once the merger is complete, ownership will be split 73% for current FOX shareholders and 27% for Roku shareholders, based on who held shares prior to the deal.

Roku founder, chair and CEO Anthony Wood will maintain an ongoing role at the combined company and will join the FOX Board of Directors following the transaction’s close in the first half of 2027.

“Over the past two decades, we’ve built Roku into the leading TV streaming platform, reaching more than 100 million households globally and reshaping how people discover and enjoy entertainment. I’m incredibly proud of what our team has built, and the combination with FOX is an extraordinary opportunity to accelerate our vision, scale faster and innovate more aggressively for viewers, partners and advertisers,” Wood said.

Advertisement

GET FOX BUSINESS ON THE GO BY CLICKING HERE

“That’s why our Board of Directors unanimously determined after concluding its strategic review process that this transaction offers a significant premium to Roku shareholders while also providing them with the opportunity to participate in the compelling future upside of the combined company,” Wood added. “I couldn’t be more excited about what we’ll accomplish together.”

The deal remains subject to customary closing conditions, including approvals by FOX and Roku shareholders and U.S. and certain non-U.S. regulatory approvals. 

Advertisement

The transaction is expected to close in the first half of calendar year 2027.

READ MORE FROM FOX BUSINESS

Continue Reading

Business

New business units near A303 approved after three-year wait

Published

on

Business Live

Brickcourt to develop eight units at the Cadbury Business Park

Entrance to the Cadbury Business Park on the A359 Cary Road in North Cadbury.

The entrance to the Cadbury Business Park on the A359 Cary Road in North Cadbury(Image: Google Maps)

New business units near the A303 in Somerset have been approved by council planning officers after three years of delays.

Advertisement

Brickcourt Ltd. put forward plans in October 2023 to deliver eight new units at the Cadbury Business Park off the A359 Cary Road in North Cadbury, a short distance north of the A303 near Sparkford.

The developer has spent the best part of three years negotiating with Somerset Council over the proposals, putting forward several different designs and addressing issues surrounding the access arrangements.

The council has now finally given these proposals the go-ahead, enabling construction to begin before the year is over.

The business park provides various units for small- and medium-sized enterprises in the parish of North Cadbury and beyond, lying on the main road between the A303 and Castle Cary.

Advertisement

Under the newly-approved plans, eight new units will be constructed within three blocks at the south-eastern edge of the site, providing just over 3,100 sq m of employment space between them.

The existing storage yard and loading area will be retained, with an attenuation pound and new landscaping being created to offset the impact of the new development and reduce the risk of localised flooding.

It is unclear how many new jobs will be created through this development, since this will depend on the tenants who ultimately occupy the units.

A spokesperson for Boon Brown Architects (representing the applicant) said: “The proposed buildings are of an appropriate size, scale, and design to the local context, and have been designed in such a way that will not cause overriding visual harm to the landscape.

Advertisement

“The development provides an appropriate variety of unit sizes, as well as the necessary amenity and parking required.

“This proposal also implements extensive landscaping works which will not only work to screen and mitigate against the impact of the proposed development, but also that of the previously constructed phases of the Cadbury Business Park.”

The council approved the plans through the delegated powers of its planning officers, rather than a public decision by its planning committee south (which handles major applications within the former South Somerset area).

Senior planning officer Ian Cousins said: “The recently adopted North Cadbury and Yarlington Neighbourhood Plan designates land at Cadbury Business Park as an employment site, to meet the needs of North Cadbury and the surrounding parishes.

Advertisement
The plans for eight new business units at the Cadbury Business Park on the A359 Cary Road in North Cadbury

The plans for eight new business units at the Cadbury Business Park on the A359 Cary Road in North Cadbury. (Image: Boon Brown Architects)

“The National Planning Policy Framework supports the provision of a prosperous rural economy, and reiterates the government’s desire to support economic growth in rural areas in order to create jobs and prosperity by taking a positive approach to sustainable new development.

“It is considered that infill of this gap between these two existing commercial sites… with a development of a similar scale and character will not have a significant detrimental impact upon landscape character.

“The proposed development will read visually with this existing built form rather than the introduction of new incongruous development within the countryside.”

Advertisement
Continue Reading

Business

Northland reiterates USA Rare Earth stock rating on facility launch

Published

on


Northland reiterates USA Rare Earth stock rating on facility launch

Continue Reading

Business

Microsoft Copilot Down Today? Copilot Experiences Widespread Outages as Users Report Access Issues

Published

on

Google Gmail

NEW YORK — Microsoft Copilot faced significant service disruptions on Monday, with thousands of users reporting difficulties accessing the AI-powered assistant across web, desktop and mobile platforms, prompting frustration among professionals relying on the tool for productivity tasks.

The outage affected Copilot’s integration with Microsoft 365 applications, including chat functions, document assistance and image generation features. Users encountered error messages, loading failures and timeout issues, with many turning to social media to share experiences using hashtags such as #CopilotDown and #MicrosoftCopilotDown.

Downdetector and other service tracking sites showed elevated reports of problems, primarily with the web interface and desktop applications. Microsoft has not yet issued a formal statement on the scope or cause of the disruptions, but users in multiple time zones reported similar issues throughout the day.

Scope of the Disruptions

Advertisement

Complaints centered on Copilot’s inability to load responses, authentication failures and general unresponsiveness. Enterprise users integrated with Microsoft 365 environments appeared particularly impacted, with some reporting that the AI assistant was unavailable in Outlook, Word, Excel and Teams.

The timing of the outage coincided with high usage periods for many professionals, amplifying the inconvenience for those depending on Copilot for drafting emails, summarizing documents or generating ideas during meetings. Some users noted intermittent functionality, suggesting the issue may involve backend server capacity or network routing problems rather than a complete system failure.

Microsoft’s service health dashboard provided limited immediate information, directing affected users to standard troubleshooting steps such as clearing cache, restarting applications or checking internet connectivity. However, many reported that these measures did not resolve the problems, indicating a broader service-side issue.

User Frustration and Workarounds

Advertisement

Social media platforms filled with posts from affected users expressing disappointment over lost productivity. Professionals in fields ranging from marketing to software development described switching to alternative AI tools or reverting to manual workflows while awaiting resolution.

Some users found temporary relief by accessing older versions of Microsoft services or using web-based alternatives, but these options lacked the seamless integration that makes Copilot valuable within the Microsoft ecosystem. Enterprise IT teams reported receiving increased support tickets as organizations scrambled to maintain operations.

The outage highlights growing dependence on AI assistants for daily work. As Copilot has become embedded in Microsoft 365 subscriptions, any disruption now carries significant business implications for millions of users worldwide.

Microsoft’s Response and History of Reliability

Advertisement

Microsoft has faced occasional Copilot outages in recent months, often linked to rapid feature rollouts or backend scaling challenges as adoption grows. The company typically resolves such issues within hours, but the frequency has raised questions about infrastructure robustness amid aggressive AI expansion.

Users are advised to monitor Microsoft’s official status pages and support channels for updates. In past incidents, the company has rerouted traffic or applied backend fixes to restore service without widespread communication.

For enterprise customers with dedicated support agreements, escalation through Microsoft 365 admin centers has proven effective in prior cases. Individual users can try signing out and back in or using the service in incognito mode as interim measures.

Broader Implications for AI Reliability

Advertisement

The disruption comes as AI tools like Copilot become central to productivity suites across industries. Reliability concerns are increasingly important as businesses integrate these technologies into core workflows, where downtime can translate directly into lost revenue or missed deadlines.

Industry analysts note that as AI assistants handle more complex tasks, the expectations for uptime rise correspondingly. Microsoft’s challenges reflect broader industry issues with scaling large language models and associated infrastructure under heavy demand.

Competitors offering similar AI productivity tools may see temporary interest spikes during Microsoft outages, though most users remain loyal to the integrated Microsoft ecosystem due to data continuity and feature depth.

Troubleshooting Guidance

Advertisement

Microsoft recommends several steps for users experiencing Copilot issues:

  • Restart the application or browser
  • Clear cache and cookies
  • Check Microsoft 365 service health status
  • Verify account permissions and licensing
  • Test on alternative devices or networks

Persistent problems should be reported through official support channels to help Microsoft identify patterns and accelerate resolution.

For organizations, IT administrators can use Microsoft 365 admin tools to monitor service health and communicate updates to end users. Proactive monitoring and backup workflows can minimize impact during such incidents.

Future Outlook for Copilot Stability

Microsoft continues to invest heavily in AI infrastructure, with ongoing expansions of data centers and optimization efforts aimed at improving reliability. The company has emphasized responsible scaling and continuous monitoring to prevent widespread disruptions.

Advertisement

As Copilot evolves with new features and deeper integration across Microsoft products, maintaining high availability will be critical to user trust and adoption rates. Past outages have typically been resolved relatively quickly, suggesting Monday’s issues may follow a similar pattern.

Users are encouraged to stay informed through official Microsoft channels rather than relying solely on social media reports, which can sometimes amplify isolated problems. As the AI landscape matures, service reliability is expected to improve alongside technological advancements.

The latest Copilot outage serves as a reminder of the challenges in delivering always-on AI services at global scale. While frustrating for affected users, such incidents also drive improvements that ultimately benefit the broader ecosystem of productivity tools.

Microsoft is expected to provide more details on the root cause and resolution timeline once the service is fully restored. In the meantime, users are adapting workflows and looking forward to resumed access to one of the most widely used AI assistants in the workplace.

Advertisement
Continue Reading

Business

Morocco stocks higher at close of trade; Moroccan All Shares up 4.46%

Published

on


Morocco stocks higher at close of trade; Moroccan All Shares up 4.46%

Continue Reading

Business

Bitcoin Surges Past $66,000 as US-Iran Peace Deal Fuels Crypto Risk-On Rally

Published

on

Bitcoin medals: the arrival of the first cryptocurrency exchange on the Nasdaq is exciting a great deal of anticipation on Wall Street

NEW YORK — Bitcoin climbed more than $2,400 on Monday, surging 3.78% to $66,363.01 as the US-Iran peace agreement and reopening of the Strait of Hormuz eased geopolitical tensions, boosting investor appetite for risk assets including cryptocurrencies.

The sharp advance pushed Bitcoin to its highest level in several weeks, reflecting renewed optimism that reduced uncertainty in the Middle East would support global economic stability and risk-taking. The move extended gains across the broader crypto market, with major tokens posting solid advances amid improving sentiment.

The ceasefire deal announced by President Donald Trump, which includes lifting the naval blockade and restoring free shipping through the critical oil waterway, removed a significant risk premium that had weighed on markets. Lower oil prices and expectations of steadier global trade flows contributed to a broad relief rally that lifted Bitcoin and other digital assets.

Peace Deal Sparks Crypto Recovery

Advertisement

Bitcoin’s performance aligned with strength in equities, where the Dow Jones Industrial Average and Nasdaq Composite reached record closes. Cryptocurrencies, often viewed as high-beta assets, amplified the positive reaction as investors rotated toward riskier holdings following the diplomatic breakthrough.

The agreement, set for formal signing in Switzerland, is expected to stabilize energy markets and reduce fears of prolonged supply disruptions. This environment generally favors speculative assets like Bitcoin, which thrive when macroeconomic uncertainty declines and liquidity conditions improve.

Market participants described the move as a classic risk-on response. Reduced geopolitical worries allowed investors to refocus on Bitcoin’s long-term narrative as a store of value and hedge against traditional financial system risks, while also benefiting from broader market momentum.

Technical and Market Drivers

Advertisement

The price breakout above key resistance levels triggered algorithmic buying and short covering, accelerating the upward move. Trading volumes were elevated as both institutional and retail participants adjusted positions in response to the fast-moving news.

Bitcoin’s dominance in the crypto market remained strong, with the total crypto market capitalization rising in tandem. Ethereum and other major tokens also posted gains, though Bitcoin outperformed on the day as investors favored the flagship asset during the relief rally.

The surge comes after a period of consolidation for Bitcoin, during which the asset navigated regulatory developments, macroeconomic data and shifting sentiment around institutional adoption. Monday’s performance suggests renewed momentum as external risks recede.

Broader Crypto Market Context

Advertisement

The cryptocurrency sector has shown resilience in 2026 despite periodic volatility. Institutional interest continues to grow through spot ETFs and corporate treasury allocations, providing structural support for prices. Monday’s move highlights Bitcoin’s sensitivity to global risk sentiment while reinforcing its appeal during periods of de-escalation.

Lower energy costs from stabilized oil markets could indirectly benefit crypto mining operations, many of which rely on power-intensive processes. Reduced input costs may improve miner profitability and support network security through sustained hash rate.

Regulatory clarity in major jurisdictions has also contributed to a more constructive backdrop for digital assets. Progress on stablecoin frameworks and clearer guidelines for crypto markets have helped legitimize the sector in the eyes of traditional finance.

Investor and Analyst Perspectives

Advertisement

Analysts offered generally positive interpretations of the price action. The combination of geopolitical relief and Bitcoin’s maturing market structure creates conditions for potential further upside, though volatility remains a defining characteristic of the asset class.

Some strategists cautioned that implementation risks around the Iran agreement could introduce renewed uncertainty, potentially pressuring prices if talks stall. However, the immediate market reaction demonstrated investors’ willingness to price in a more benign outlook.

Institutional flows into Bitcoin products have remained supportive, with exchange-traded funds seeing steady inflows in recent periods. Retail participation also picked up on the positive news, contributing to the session’s momentum.

Long-Term Outlook and Risks

Advertisement

Bitcoin’s role as a digital store of value continues to evolve as adoption grows among institutions, corporations and sovereign entities. The asset’s fixed supply and decentralized nature appeal to investors seeking alternatives to traditional currencies amid fiscal concerns and monetary policy shifts.

Challenges persist, including regulatory uncertainty in certain jurisdictions, energy consumption debates around mining, and competition from other digital assets. Nevertheless, Bitcoin’s market leadership and network effects provide a strong foundation for long-term growth.

Monday’s surge to $66,000 levels reinforces Bitcoin’s resilience and its correlation with broader risk assets during positive developments. As the crypto market matures, such moves are increasingly viewed through the lens of macroeconomic and geopolitical factors alongside technology-specific drivers.

Investment Considerations

Advertisement

Investors are reminded that cryptocurrency prices remain highly volatile and suitable only for those with appropriate risk tolerance. Diversification, thorough research and long-term perspective are essential when considering exposure to Bitcoin or the broader crypto market.

Financial advisers recommend allocating only what one can afford to lose and staying informed about regulatory and technological developments. While the latest rally is encouraging, sustainable gains will depend on continued institutional adoption and favorable macroeconomic conditions.

The session serves as a reminder of crypto’s sensitivity to global events while highlighting its potential as a portfolio diversifier. With prices at elevated levels, all eyes will remain on how Bitcoin navigates the balance between relief-driven gains and fundamental value drivers in the weeks ahead.

As markets digest the US-Iran agreement, Bitcoin’s performance underscores its evolving role in global finance. The asset’s ability to rally amid improving risk sentiment demonstrates both its speculative appeal and its growing maturity as a recognized store of value in uncertain times.

Advertisement

The coming days will bring further clarity on the peace deal’s implementation and its lasting impact on market dynamics. For Bitcoin enthusiasts and investors alike, Monday’s record push above $66,000 marks a notable milestone in an eventful year for digital assets.

Continue Reading

Business

Bitmine stock jumps 8.2% on $10.4B ETH holdings disclosure

Published

on


Bitmine stock jumps 8.2% on $10.4B ETH holdings disclosure

Continue Reading

Trending

Copyright © 2025