Connect with us

Business

VA Launches Nationwide Clinical Trial Testing GLP-1 Drugs as Alcohol Addiction Treatment for Veterans

Published

on

Low-Sugar Diet in a Baby's First 1,000 Days Linked to

The U.S. Department of Veterans Affairs is launching a nationwide clinical trial to determine whether a class of medications best known for treating diabetes and obesity can also help veterans struggling with alcohol addiction, the agency announced Thursday.

The VA said it will enroll more than 600 veterans in the study, which will evaluate semaglutide, a GLP-1 receptor agonist widely used to treat Type 2 diabetes and obesity. Researchers are investigating whether the medication, sold under brand names including Ozempic and Wegovy for its approved uses, may also reduce alcohol consumption by affecting the brain’s reward system, the same neural circuitry believed to play a central role in the drug’s appetite-suppressing effects.

Participants in the study, ages 18 to 80, will need to have moderate or severe alcohol use disorder to qualify for enrollment. Those selected will receive weekly injections of either semaglutide or a placebo over a 24-week treatment period, followed by a subsequent safety follow-up phase. Throughout the trial, researchers will track changes in participants’ drinking habits, overall physical health and quality of life to assess whether the medication could eventually become a viable new treatment option for alcohol use disorder.

The study, formally titled the Cessation or Reduction of Alcohol Consumption in Veterans trial, will be conducted at 18 VA medical centers across the country, including facilities in Los Angeles, Long Beach and Palo Alto, California.

Advertisement

GLP-1 medications were originally developed and approved specifically to treat Type 2 diabetes, but have since become widely known to the public primarily for their effectiveness in promoting weight loss. Researchers have continued studying the broader class of drugs for potential benefits extending well beyond their original indications, including possible effects on heart health, chronic inflammation and other conditions unrelated to blood sugar control or body weight.

The scale of alcohol use disorder within the veteran population has driven the VA’s interest in exploring new treatment approaches. According to the agency, more than 400,000 veterans nationwide have received a diagnosis of alcohol use disorder. An analysis published earlier this year found that patients taking GLP-1 medications experienced lower rates of both alcohol use disorder and other substance use disorders compared with similar patients taking different diabetes medications, a finding that prompted researchers to investigate the drugs’ potential more directly through a controlled clinical trial.

VA Secretary Doug Collins framed the trial as an example of the kind of research the department is uniquely positioned to carry out given its direct focus on veteran health outcomes. “This clinical trial reflects medical research that VA is uniquely situated to launch, and is aimed directly at benefitting Veterans,” Collins said in a statement. “By exploring emerging treatment options like the use of a GLP-1 for AUD, we aim to expand the tools available to help Veterans take control of their health and recovery.”

Recruitment for the study began this week, according to VA officials. The department emphasized that veterans should not attempt to self-medicate with GLP-1 medications or discontinue proven, existing alcohol use disorder treatments without first consulting their health care providers, given that the trial remains an experimental research study rather than an approved treatment protocol.

Advertisement

Alcohol use disorder remains one of the most common and challenging conditions facing the veteran population, often occurring alongside other service-related health issues, including post-traumatic stress disorder, chronic pain and other mental health conditions. Existing treatment options for the condition include several FDA-approved medications, along with a range of behavioral therapies and support programs, though researchers and clinicians have continued searching for additional treatment approaches given that no single existing option works effectively for every patient.

The scientific interest in GLP-1 medications for addiction treatment extends beyond alcohol use disorder specifically. Researchers studying the broader class of drugs have also examined their potential effects on other substance use disorders, building on observational data suggesting the medications may influence the same underlying neural reward pathways implicated in various forms of addictive behavior, not solely those related to food intake and appetite regulation.

The VA’s trial adds to a growing body of ongoing research into GLP-1 medications’ effects well beyond their original diabetes and weight-loss indications, as the drugs have continued attracting significant scientific and public interest since their initial approval and rapid rise in popularity in recent years.

Given that this trial involves veterans managing alcohol use disorder, a serious and potentially life-threatening condition, anyone personally struggling with alcohol use or addiction is encouraged to speak directly with a healthcare provider about existing treatment options rather than waiting for or relying on the results of this ongoing research study, and veterans specifically can contact their local VA medical center for information about current treatment resources and potential eligibility for enrollment in the trial as recruitment continues.

Advertisement
Continue Reading
Click to comment

You must be logged in to post a comment Login

Leave a Reply

Business

Kuwait International Airport Is Open Today, but Terminal 1 Remains Closed Amid Fresh Iranian Strikes

Published

on

Kuwait International Airport

Kuwait International Airport is open and operating on Saturday, with two of its five terminals handling scheduled commercial flights even as the country continues absorbing the fallout from a fresh Iranian drone strike on a nearby military air base a day earlier.

Kuwait Airways is flying out of Terminal 4, while Jazeera Airways operates from Terminal 5, with both national carriers maintaining largely normal schedules, according to travel monitoring service Wego. Terminal 1, the airport’s primary international facility, remains closed pending repairs and has no confirmed reopening date, a status that has persisted since the terminal suffered significant structural damage, including a partial roof collapse, during a strike in early June. Terminal 2 remains under construction, with completion targeted for late 2026, while Terminal 3 has been permanently closed.

Friday’s Iranian strike targeted the Ahmad al-Jaber Air Base, a separate military installation located roughly 40 miles south of Kuwait City that hosts both Kuwaiti and U.S. air force operations, rather than Kuwait International Airport itself. Iran’s military said in a statement that its forces had used loitering drones to target aircraft shelters, satellite communications systems and equipment storage facilities at the base, describing the strike as the 27th phase of an ongoing military operation carried out in retaliation for a U.S. attack on a residential home on Iran’s Qeshm Island. The Iranian army characterized Ahmad al-Jaber as a major hub for U.S. air and surveillance operations and a key logistical support center for American forces in the region, according to Al Jazeera’s reporting on the strike.

Kuwait’s Public Authority for Civil Aviation had not announced any new closure of the commercial airport specifically in connection with Friday’s strike on the separate military base, according to the most recent available travel status reporting. Even so, the broader pattern of the conflict has repeatedly demonstrated how quickly conditions at the civilian airport can shift in response to regional developments. Kuwait closed its airspace and suspended all takeoffs and landings on July 18 as a precautionary measure amid missile and drone threats and active air-defense intercepts, with operations resuming the following day, according to Wego.

Advertisement

The damage that continues to keep Terminal 1 offline traces back to a sustained campaign of Iranian-linked drone and missile attacks that began in late February and has periodically struck Kuwaiti territory throughout the year as part of the broader U.S.-Iran conflict. Kuwait’s Defense Ministry has previously said its forces detected roughly 30 ballistic missiles and drones launched by Iran in a single day during that earlier period, with several intercepted over residential areas. Kuwait’s foreign ministry summoned Iran’s charge d’affaires at the time to lodge a formal protest and ordered two Iranian embassy staff to leave the country within 24 hours. Iran’s Revolutionary Guard denied responsibility for that particular attack, with a spokesman claiming the damage was instead caused by a failed U.S. interceptor missile, an account U.S. Central Command rejected, calling it a deliberate Iranian drone strike on the airport.

Terminal 1 had briefly reopened on June 1, allowing some non-Kuwaiti carriers to resume service through the facility after an earlier closure, but that reopening proved short-lived. The terminal suffered more severe structural damage, including the partial roof collapse, during a subsequent strike on June 3, rendering the facility unsafe for passenger operations and prompting officials to close it again, a closure that has remained in effect since. Kuwait Airways resumed flights from Terminal 4 within hours of that June 3 strike, reflecting the country’s determination to maintain at least limited air traffic even amid continued security threats.

Sheikh Hamoud Mubarak Al Sabah, chairman of Kuwait’s General Civil Aviation Authority, has said the airport’s phased reopening process has been coordinated closely with domestic and international authorities to ensure operations resume in line with the highest safety and security standards, rather than restoring full capacity all at once.

Beyond the immediate recovery effort tied to Terminal 1, Kuwait continues advancing a longer-term expansion of its aviation infrastructure. A new Terminal 2, designed by the architecture firm Foster + Partners and built around a triangular structure, remains under construction and is targeted for completion in the final quarter of 2026. Once finished, the facility is expected to add dozens of additional gates, thousands of new parking spaces and an on-site hotel, expanding the airport’s overall passenger handling capacity to more than 25 million travelers annually. That expansion project has faced its own disruptions over the years, including delays tied to the COVID-19 pandemic and, more recently, minor damage to the construction site from an earlier Iranian drone strike that did not affect the project’s planned completion timeline.

Advertisement

Travel advisories tied to the broader U.S.-Iran conflict have continued shifting in response to developments on the ground, and travel monitoring services have consistently urged passengers to confirm their specific flight status directly with their airline before heading to the airport, given how frequently conditions have changed throughout 2026. Passengers flying with Kuwait Airways should expect to depart from Terminal 4, while those flying with Jazeera Airways will use Terminal 5. Anyone whose itinerary was originally booked through Terminal 1 should check with their airline regarding rebooking, alternate terminal arrangements or refund options, since that facility remains offline with no confirmed date for restoring passenger operations.

Continue Reading

Business

Banco De Chile earnings beat, revenue topped estimates

Published

on


Banco De Chile earnings beat, revenue topped estimates

Continue Reading

Business

Hargreaves Services Plc (HGRVF) Q4 2026 Earnings Call Transcript

Published

on

OneWater Marine Inc. (ONEW) Q1 2026 Earnings Call Transcript