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Bitcoin is now front-running the Fed rather than reacting to it. ETFs are the cause

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(Binance Research)

Bitcoin may no longer move in step with Federal Reserve policy, according to a new report from Binance Research, which points to a structural shift driven by spot exchange-traded funds.

For years, crypto markets reacted sharply to interest rate signals, with bitcoin falling when central banks tightened monetary policy.

That pattern now appears to be breaking as Binance data shows bitcoin’s correlation with its Global Easing Breadth Index, which tracks 41 central banks, has turned strongly negative since 2024. Spot bitcoin ETFs were approved by the U.S. Securities and Exchange Commission (SEC) in January 2024.

(Binance Research)

Before ETFs, the relationship was mildly positive, with BTC tending to follow global easing cycles by several months. Now, the report finds the opposite effect is nearly three times stronger, suggesting the old link has reversed.

The change reflects a shift in who drives prices. Retail investors once dominated crypto trading and reacted to macro news. ETFs allowed institutions to play a bigger role, and these firms often positioned months ahead of policy changes, treating BTC as a forward-looking asset.

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“As a result, BTC may have evolved from a macro ‘lagging receiver’ to a ‘leading pricer,” Binance Research wrote. “A peak in easing may already be old news for BTC, and crypto-native drivers—such as policy progress and institutional flows—could matter more than the direction of monetary easing itself.”

The findings come as markets grapple with renewed stagflation fears tied to rising oil prices and growing geopolitical tensions over the war in the Middle East.

Rate expectations have swung from projected cuts to possible hikes, a backdrop that historically pressured risk assets.

Binance argues that the reaction may be overstated. In past cycles, central banks often pivoted to support growth despite inflation spikes. If history repeats itself, central banks are to eventually prioritize growth over inflation, and bitcoin will likely price that pivot earlier than expected.

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Samsung stock rises as AI chip boom drives sharp profit growth

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Samsung stock rises as AI chip boom drives sharp profit growth

Samsung Electronics’ shares got a nice boost on Tuesday morning after the company predicted a record-breaking quarter fueled by the massive boom in AI hardware. The stock jumped as much as 4.8% during the day before settling into a 1.76% gain by the close.

Summary

  • Samsung Electronics shares rose after forecasting record Q1 profit, driven by strong AI memory demand.
  • Operating profit is projected at 57.2 trillion won, more than eight times higher year over year and above analyst estimates.
  • Supply chain risks tied to Middle East tensions could disrupt chip materials like helium and weigh on the outlook if prolonged.

According to its early estimates, Samsung is looking at an operating profit of roughly 57.2 trillion won, which is about $37.8 billion, for the first quarter. To put that massive figure in perspective, it is more than eight times what the company made during the same time last year.

If these numbers hold, it will set a brand new quarterly record for the company. The projected profit is nearly triple their previous all-time high and easily crushed the 42.3 trillion won that analysts were originally expecting.

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The revenue side looks just as impressive. Samsung expects sales to hit about 133 trillion won, which is a nearly 70% jump year over year. This would also mark the first time the company’s quarterly revenue has ever crossed the 100 trillion won threshold.

MS Hwang, a research analyst at Counterpoint Research, told CNBC that Samsung’s latest numbers are so huge that they are now rivaling the scale of global Big Tech giants.

The strong outlook is largely tied to demand for high-bandwidth memory, or HBM, a critical component used in accelerators from companies like NVIDIA and AMD that power artificial intelligence workloads. Expansion of data centers and rapid growth in AI model training have significantly increased memory requirements, tightening supply and pushing prices higher.

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Industry projections suggest memory prices tied to data center applications will continue rising in the coming months. Samsung’s earnings trajectory shows how deeply the AI boom has translated into financial performance, with memory chips forming the core of its profit engine.

Demand for HBM has surged over the past year, leading to supply shortages across the memory market and driving sharp increases in both pricing and shipment volumes. Hwang noted that commodity memory prices could rise by more than 50% in the second quarter, with tight supply conditions expected to persist.

Samsung is also looking to regain its footing in the high-bandwidth memory segment after ceding early leadership to domestic rival SK Hynix, which was quicker to supply advanced AI memory.

Samsung’s Device Solutions division, which houses its memory chip business, accounted for 39% of total revenue and 57% of operating profit in 2025, underlining the segment’s importance to overall earnings.

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The company is set to release its full earnings report later this month. While current projections point to strong performance, external risks remain.

Geopolitical risks in focus

Rising tensions in the Middle East are starting to disrupt semiconductor supply chains, with shipments of key materials such as helium facing delays.

The U.S.–Israel conflict involving Iran has raised concerns about access to these inputs, which are essential for chip production, increasing the risk of operational challenges for major manufacturers like Samsung Electronics and SK Hynix.

“If the Middle East conflict ends quickly, it will not significantly impact profits. However, if it persists for several months or longer, it will lead to severe consequences,” Hwang said.

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index drops 2.4% as all constituents trade lower

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9am CoinDesk 20 Update for 2026-04-07: vertical

CoinDesk Indices presents its daily market update, highlighting the performance of leaders and laggards in the CoinDesk 20 Index.

The CoinDesk 20 is currently trading at 1917.55, down 2.4% (-47.87) since yesterday’s close.

All 20 assets are trading lower.

9am CoinDesk 20 Update for 2026-04-07: vertical

Leaders: BCH (-1.0%) and CRO (-1.0%).

Laggards: AAVE (-8.5%) and AVAX (-7.6%).

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The CoinDesk 20 is a broad-based index traded on multiple platforms in several regions globally.

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Operation Atlantic Targets Crypto Scam Networks With Real-Time Tracking

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Operation Atlantic Targets Crypto Scam Networks With Real-Time Tracking

Operation Atlantic: A proactive strike against evolving crypto scams

Crypto scams have become highly sophisticated cross-border operations that exploit advanced technology and human psychology. By the time victims become aware of the fraud, the stolen cryptocurrency is often rapidly dispersed across a chain of wallets and exchanges in multiple countries.

Operation Atlantic represents a coordinated international effort by law enforcement agencies from the US, the UK and Canada to counter this threat. Rather than limiting itself to post-incident investigations, the operation focuses on identifying, tracking and disrupting crypto scams while they are still in progress.

The initiative brings together key agencies, including the US Secret Service, the US Attorney’s Office for the District of Columbia, the Ontario Provincial Police, the Ontario Securities Commission, the Royal Canadian Mounted Police, the UK Financial Conduct Authority, the UK National Crime Agency and the City of London Police.

Contrary to conventional investigations that begin only after funds have been stolen, Operation Atlantic is structured to:

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  • Identify victims who are at risk

  • Detect active scam infrastructure

  • Interrupt fraudulent transactions

  • Help recovery efforts where feasible

Officials have stressed that the primary objective is to disrupt scams in near real time, marking a significant shift toward faster, more proactive enforcement strategies.

Why approval phishing lies at the heart of Operation Atlantic

A particular form of fraud known as approval phishing lies at the center of Operation Atlantic. Rather than stealing private keys or seed phrases, attackers deceive users into signing what appear to be legitimate blockchain transactions.

These transactions grant scammers permission to spend tokens directly from a victim’s wallet. Once approval is given, the attacker gains the ability to:

This makes approval phishing particularly dangerous. Victims often remain unaware that anything is wrong until their assets begin disappearing.

Scammers frequently integrate this technique into larger scams, such as fake investment platforms or gradual trust-building schemes.

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From investigation to intervention

The standout feature of Operation Atlantic is its emphasis on real-time disruption rather than post-event analysis.

This strategy rests on a straightforward idea: While crypto transactions are irreversible, they are also public and fully traceable.

By using blockchain analytics, authorities and private-sector partners can:

  • Detect suspicious wallet activity

  • Identify addresses linked to known scams

  • Track fund flows toward exchanges or liquidity pools

  • Alert platforms and investigators

  • Contact victims before their funds are completely drained

This model does not guarantee full recovery, but it opens a critical window during which meaningful intervention remains possible.

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Did you know? The US Secret Service, originally established to combat currency counterfeiting in 1865, now tracks crypto fraud using blockchain analytics. It is one of the oldest agencies adapting to one of the newest financial systems.

Building on earlier initiatives

Operation Atlantic did not happen overnight. It builds upon earlier efforts such as Project Atlas, which was launched in 2024 by Canadian authorities in partnership with the US Secret Service to target crypto fraud networks.

It also draws on lessons from Operation Spincaster, an effort that involved blockchain analytics firms, exchanges and law enforcement agencies.

Spincaster demonstrated that coordinated action could deliver tangible results:

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  • Thousands of scam-linked wallet leads identified

  • Significant losses mapped across jurisdictions

  • In some cases, victims were warned in time to revoke malicious approvals

These initiatives suggest that crypto fraud can be interrupted while it is still in progress.

What “real time” actually means

The concept of real-time disruption is sometimes misunderstood. It does not mean instant recovery or guaranteed prevention.

Instead, it operates across three stages:

  • Pre-loss prevention: spotting suspicious approvals before funds are moved

  • Mid-transaction disruption: flagging or freezing assets during transfers

  • Post-loss response: attempting recovery after funds have been dispersed

Operation Atlantic concentrates mainly on the first two stages, where intervention is still feasible.

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Its success depends on how quickly data can be analyzed, shared and acted upon across borders and platforms.

Did you know? Approval phishing scams often exploit wallet permissions rather than passwords, which means victims technically authorize the theft themselves. This psychological twist makes these scams harder to detect than traditional hacking attempts.

Why scams now operate like organized networks

Approval phishing scams are generally not standalone events. They typically operate as structured networks with several interconnected parts:

  • Social engineering pipelines to attract victims

  • Fake interfaces or decentralized applications

  • Wallet approval mechanisms

  • Consolidation addresses used to pool stolen funds

  • Exchange off-ramps for cashing out

This layered setup allows scammers to scale their operations while reducing the likelihood of detection.

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Operation Atlantic treats these scams as coordinated financial networks rather than isolated crimes, an approach that is central to its real-time disruption strategy.

The scale of the problem

The urgency behind Operation Atlantic stems from the enormous scale of crypto fraud.

Approval phishing alone has been linked to billions of dollars in losses in recent years, affecting thousands of victims across multiple jurisdictions.

Even more concerning is that many incidents go unreported, suggesting the true losses may be substantially higher.

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Monthly figures also show that while overall exploit losses may vary, phishing attacks continue to rise, confirming that user-targeted scams remain one of the most persistent threats in crypto.

Did you know? Law enforcement agencies increasingly use blockchain clustering to map entire scam networks, sometimes revealing thousands of linked wallets behind a single fraud operation. This forensic technique groups related wallet addresses.

The role of public-private coordination

A key aspect of Operation Atlantic is the close partnership between law enforcement and private-sector organizations.

Each participant contributes in specific ways:

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  • Blockchain analytics firms identify suspicious patterns and wallet clusters

  • Exchanges monitor inflows and flag deposits linked to scams

  • Stablecoin issuers may help freeze funds in targeted cases

  • Platforms and wallets can warn users or block malicious interactions

This level of coordination enables faster responses than conventional investigations, which often rely on slower legal procedures.

At the same time, it raises expectations for platforms to play a more active role in fraud detection.

The limits of real-time disruption

Despite its goals, Operation Atlantic faces several structural constraints:

  • Once funds are bridged or layered across multiple services, recovery becomes extremely difficult

  • User behavior remains a major vulnerability, particularly in social engineering scenarios

  • Cross-border legal processes can still delay enforcement actions

  • Wallet anonymity makes victim identification more complicated

In many cases, the most realistic outcome is preventing further losses rather than achieving full recovery of stolen assets.

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What this means going forward

Operation Atlantic reflects a broader shift in how crypto-related crime is being tackled.

Rather than viewing fraud as a fixed, one-time event, authorities now treat it as a dynamic, ongoing process that can be monitored and disrupted while it is still in progress.

For users, this shift may result in:

  • More frequent warnings about suspicious transactions

  • Greater emphasis on understanding wallet permissions

  • Increased awareness of scam risks

For platforms, it could lead to:

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  • Higher expectations for transaction monitoring

  • Deeper collaboration with law enforcement

  • Integration of real-time risk detection tools

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Biogen (BIIB) Partners With Alloy Therapeutics on Antisense Drug Platform

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BIIB Stock Card

Key Takeaways

  • Biogen has entered into a multi-target partnership with Alloy Therapeutics to leverage Alloy’s AntiClastic™ ASO technology for developing antisense therapeutics.
  • Financial terms include upfront compensation for Alloy, along with potential milestone-based payments and tiered royalty structures.
  • The partnership builds on an existing relationship dating back to 2020, which initially centered on antibody-based therapies.
  • RBC Capital reduced Biogen’s price target from $233 to $213 while maintaining its Outperform recommendation.
  • Wall Street analysts have established a consensus price target of $210.30 for BIIB with an overweight rating.

Biogen has formalized a strategic partnership with Alloy Therapeutics, securing rights to utilize Alloy’s proprietary AntiClastic™ antisense oligonucleotide (ASO) technology platform for developing therapies targeting several yet-to-be-disclosed disease areas.


BIIB Stock Card
Biogen Inc., BIIB

Under the terms of the arrangement, Alloy Therapeutics will collect an initial payment, with opportunities to earn additional compensation through development and commercial milestones, plus royalty payments tied to any successfully marketed products.

While the two biotechnology firms have maintained a collaborative relationship since 2020, their previous work concentrated on antibody-based treatment development. This latest agreement marks a strategic shift toward genetic medicine applications.

Biogen brings substantial experience to ASO drug development. The company’s Spinraza, approved for treating spinal muscular atrophy, represents one of the commercial success stories in antisense therapy. This new collaboration aims to expand that expertise through Alloy’s technology platform.

Alloy CEO Errik Anderson characterized the partnership straightforwardly: “Biogen is a leader in the space and has made huge contributions to ASO technologies. We view this as validation and an opportunity to build on their experience.”

The collaboration will prioritize three key objectives for Alloy’s platform: increasing therapeutic potency, reducing immunogenic responses, and improving targeted tissue delivery.

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Alloy’s Expanding Partnership Portfolio

Headquartered in Waltham, Massachusetts, Alloy has established a business model centered on collaborative drug discovery and development with biopharmaceutical companies. Since launching in 2017, the company has executed approximately 200 partnership agreements, with over 100 producing licensed therapeutic candidates.

The platform has contributed to 22 drug candidates that have advanced into clinical testing. In 2024, Sanofi entered into an agreement potentially worth up to $400 million to access this same ASO technology for developing central nervous system treatments.

Christian Cobaugh, who leads Alloy’s Genetic Medicine Division as CEO, indicated the Biogen collaboration will enable the company to expand its involvement beyond initial discovery phases into later-stage development activities.

Alloy differentiates itself from typical platform biotechnology companies by focusing exclusively on partnerships rather than developing an internal proprietary pipeline.

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Wall Street’s Perspective on Biogen

From an analyst perspective, RBC Capital Markets revised its price target for BIIB downward to $213 from a previous $233 on April 7, though the firm maintained its Outperform rating.

According to FactSet’s analyst consensus data, the mean price target for Biogen shares currently sits at $210.30, accompanied by an overweight rating across the Street.

BIIB shares declined 2.82% on the trading day when the partnership was publicly announced.

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XRP Supply in Profit Mirrors 2022 Bear Market Levels: Is $1.10 Next?

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XRP Supply in Profit Mirrors 2022 Bear Market Levels: Is $1.10 Next?

XRP (XRP) is staring at a potential drop toward $1.10, as a decline in profitable supply suggests growing bearish momentum and a classic setup for new lows.

Key takeaways:

  • XRP supply in profit has dropped to 43%, levels last seen in November 2024.

  • Investors have continued selling their XRP holdings, realizing losses at $110 million per day.

  • XRP rising wedge breakdown targets $1.10. 

XRP supply in profit drops below 50%

As of Tuesday, 43% of all XRP coins were in profit, levels last seen in November 2024, according to onchain data resource Glassnode.

Historically, the metric’s drop below 50% has signaled a transition from optimism to despair characterized by panic selling and high capitulation, as seen in the last stages of previous bear markets.

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Related: XRP risk-reward improves as whale accumulation rises: Will price follow?

Between January and June 2022, for instance, XRP price dropped to $0.30 from over $0.75, a decline coinciding with XRP’s profitable supply falling to as low as 20% from just under 50%. A similar scenario was seen in 2018 when XRP price dropped another 70%, with the supply in profit going as low as 15%.

XRP supply in profit. Source: Glassnode

In fact, investors who accumulated XRP above $2 over the last 12 months “have been realizing losses at a pace of $20M–$110M/day since November 2025,” Glassnode added

XRP: Realized loss by age. Source: Glassnode

In a Tuesday post on X, analyst Crypto Town Hall said this “reflects widespread holder drawdowns, often seen during late-stage corrections,” leading to sharp drops as holders continue realizing losses.

Additionally, the average wallets active on the XRP Ledger over the past year are down 41% on their investments.

“This is the lowest MVRV (Mean Value to Realized Value) for XRP traders since the FTX crash in November, 2022,” onchain data resource Santiment said in a Tuesday post on X, adding:

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“Significantly negative average returns imply that there is much lower risk than average in buying or adding on to your $XRP positions, due to the fact that competing traders are already in severe ‘blood in the streets’ territory.”

Cryptocurrencies, XRP, Markets, Price Analysis, Market Analysis, Altcoin Watch
XRP Ledger: XRP MVRV data. Source: Santiment

This means fresh selling could be coming as investors seek to cut their losses, a key ingredient in keeping the downtrend going toward the $1.10 target.

XRP rising wedge breakdown targets $1.10

XRP/USD is in the breakdown phase of a rising wedge on the daily time frame, a bearish pattern that forms when price compresses inside two upward-sloping trendlines after a sharp decline.

XRP/USD daily price chart. Source: Cointelegraph/TradingView

The price slipped below the wedge’s lower trend line at $1.37 on March 27 and is now attempting a typical post-breakdown retest near the 50-day simple moving average around $1.38. That area is acting as immediate resistance.

If XRP fails to reclaim the trendline and moving averages, the setup points to a deeper move toward the pattern’s measured target near $1.10, roughly 16% below the current levels.

This is close to predictions by Polymarket bettors who price in a 57% chance that XRP price will hit $1.20 before the end of April.

XRP price targets for April. Source: Polymarket

As Cointelegraph reported, if bulls fail to reclaim the moving averages and the price breaks below $1.27, the XRP price risks falling toward $1.11 and eventually to the $1 psychological level.