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Guardant Health Stock Jumps 10% to $108 on Momentum From Record Q1 Revenue Beat and Raised Guidance

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Roivant Sciences Shares Jump 14.43% to $32.28 on Strong IMVT-1402

NEW YORK — Guardant Health Inc. (NASDAQ: GH) shares surged more than 10% in midday trading Wednesday, reaching $108.28, up $10.08 or 10.27%, as of 11:46 a.m. EDT, extending gains from strong first-quarter results and an upward revision to full-year revenue guidance.

The precision oncology company reported first-quarter 2026 revenue of $301.7 million on May 7, an increase of 48% from $203.5 million in the year-ago period. The results beat analyst estimates of approximately $278 million to $279 million.

Oncology revenue rose 36% to $205.0 million, driven by approximately 86,000 tests, up 47% year-over-year. Screening revenue jumped more than 600% to $41.6 million, with about 44,000 Shield tests performed compared to 9,000 in the prior-year quarter. Biopharma and data revenue increased 17% to $53.0 million.

Helmy Eltoukhy, co-founder and co-CEO, said in the earnings release: “Our first-quarter revenue increased 48% year over year, reflecting strong momentum across the Guardant portfolio.”

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AmirAli Talasaz, co-founder and co-CEO, added: “We are pleased with our progress with Shield, including strong volume momentum exiting the first quarter.”

The company raised its 2026 revenue guidance to $1.30 billion to $1.32 billion, representing 32% to 34% growth over 2025. That compares to the prior outlook of $1.25 billion to $1.28 billion.

Non-GAAP gross margin improved to 66% from 65% a year earlier. The company reported a net loss of $112.1 million, or $0.85 per share, compared with a net loss of $95.2 million, or $0.77 per share, in the first quarter of 2025. Non-GAAP loss per share was $0.45, beating consensus estimates of about $0.47.

Guardant Health ended the quarter with strong test volume growth across segments. It has surpassed $1 billion in trailing 12-month revenue, marking a key milestone.

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The stock closed at $98.19 on May 19, up 2.64% for that session. Wednesday’s move pushed the shares well above recent levels, with market capitalization exceeding $14 billion. The 52-week range stands at roughly $36 to $120.

Recent analyst actions have been positive. Piper Sandler raised its price target to $135 from $130. JPMorgan increased its target to $135 from $130. Baird lifted its target to $129 from $120. Multiple firms including Barclays, William Blair, Guggenheim and BTIG maintained buy ratings following the earnings report.

The company has formed several partnerships. It announced a nationwide collaboration with Quest Diagnostics to expand access to the Shield colorectal cancer screening test. It launched Shield Multi-Cancer Detection in Asia through a partnership with Manulife. It entered a multi-year strategic collaboration with Nuvalent to develop companion diagnostics using the Guardant Infinity platform.

Guardant Health also received U.S. FDA approval for Guardant360 Liquid CDx. It continues work on submissions to MolDx for broader reimbursement.

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Chief Financial Officer Michael Bell discussed operational improvements on the May 7 earnings call, noting progress in cost discipline and higher selling prices contributing to margin gains. The company expects free cash flow burn of $185 million to $195 million for 2026, better than the prior year.

Headcount and infrastructure investments support commercial expansion, particularly for Shield. The test targets colorectal cancer screening in average-risk adults, addressing a large unmet need where compliance with traditional methods remains low.

Analysts project continued growth in both therapy selection and early detection segments. Oncology test reimbursement has improved, supporting average selling prices in the $3,000 to $3,100 range for Guardant360 Liquid.

The broader precision oncology market has seen increased adoption of liquid biopsy technologies. Guardant Health competes with firms offering similar blood-based genomic profiling while differentiating through its screening pipeline.

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Insider activity included sales by executives in recent weeks. Co-CEO AmirAli Talasaz sold shares in May, consistent with planned trading programs. Such transactions do not reflect changes in operational outlook.

Guardant Health, headquartered in Palo Alto, California, employs approximately 2,500 people. It focuses on liquid and tissue biopsies for therapy selection, monitoring and early detection across multiple cancer types.

The company has expanded internationally and through laboratory partnerships to increase test accessibility. Its Guardant Infinity platform supports multiomic analysis for drug development and companion diagnostics.

Investors continue to monitor quarterly test volumes, reimbursement trends and progress toward profitability. The raised guidance reflects confidence in sustained commercial momentum and partnership contributions.

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Shares have shown volatility typical of growth-oriented health care stocks but have trended higher year-to-date on execution of clinical and commercial milestones. Upcoming catalysts include further regulatory decisions and additional data readouts from Shield and other programs.

Guardant Health reiterated its long-term strategy of reinvesting in scale initiatives for product innovation, commercial reach and operational efficiency. It aims to maintain leadership in the liquid biopsy space while expanding into multi-cancer early detection.

The midday surge on May 20 came amid broader market conditions and sector rotation toward health care names with strong growth profiles. Trading volume exceeded recent averages as the stock approached levels not seen consistently since earlier in the year.

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TDK Corporation: Focus On M&A Deals And AI Opportunities (OTCMKTS:TTDKY)

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TDK Corporation: Focus On M&A Deals And AI Opportunities (OTCMKTS:TTDKY)

This article was written by

The Value Pendulum is an Asian equity market specialist with over a decade of experience on both the buy and sell sides.He is the author of the investing group Asia Value & Moat Stocks, providing ideas for value investors seeking investment opportunities listed in Asia, with a particular focus on the Hong Kong market. He hunts for deep value balance sheet bargains and wide moat stocks and provides a range of watch lists with monthly updates within his investing group.

Analyst’s Disclosure: I/we have no stock, option or similar derivative position in any of the companies mentioned, and no plans to initiate any such positions within the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it (other than from Seeking Alpha). I have no business relationship with any company whose stock is mentioned in this article.

Seeking Alpha’s Disclosure: Past performance is no guarantee of future results. No recommendation or advice is being given as to whether any investment is suitable for a particular investor. Any views or opinions expressed above may not reflect those of Seeking Alpha as a whole. Seeking Alpha is not a licensed securities dealer, broker or US investment adviser or investment bank. Our analysts are third party authors that include both professional investors and individual investors who may not be licensed or certified by any institute or regulatory body.

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Sebi revamps ETF trading rules, introduces dynamic price bands from September

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Sebi revamps ETF trading rules, introduces dynamic price bands from September
Markets regulator Sebi has introduced a new framework for exchange traded funds (ETFs), replacing the existing fixed price band mechanism with dynamic price bands for most ETF categories and changing the method used to determine their base price.

The new rules will come into effect from September 1, 2026, according to a circular issued by the regulator on Monday.

At present, ETFs are subject to a fixed 20% price band based on the net asset value (NAV) from two trading days earlier. SEBI said the existing framework creates challenges because of the one-day lag in price discovery and because the fixed bands do not adequately reflect movements in the underlying assets.

Under the revised framework, equity ETFs and debt ETFs, excluding overnight and liquid ETFs, will have an initial dynamic price band of 10%, which can be expanded up to 20% after a cooling-off period. The price band will be widened by 5% increments if prices hit the upper threshold during trading.

Commodity ETFs tracking gold and silver will have an initial price band of 6%, which can be expanded in stages of 3% depending on market conditions and international commodity price movements.

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Sebi has also changed the methodology for determining ETF base prices. Instead of using the T-2 NAV, exchanges will use the previous day’s closing price, calculated as the volume-weighted average price during the last 30 minutes of trading. If there is no trade during that period, the last traded price will be used. In the absence of any trading, the latest available NAV will serve as the base price.
The regulator said stock exchanges and mutual funds should work towards using the previous day’s closing NAV as the base price from April 1, 2027.In another key change, Sebi has mandated a pre-open call auction session for gold and silver ETFs to improve price discovery, given that the underlying commodities trade continuously across international markets while domestic ETFs trade only during Indian market hours.

The regulator said the changes were based on recommendations from stock exchanges, the Secondary Market Advisory Committee and feedback received during public consultation.

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AMG Yacktman Fund Q1 2026 Commentary

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Hercules Capital: 3 Reasons Why The Market Is Wrong (Rating Upgrade)

AMG Yacktman Fund Q1 2026 Commentary

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A Guide to the Biggest Winners From the SpaceX IPO

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A Guide to the Biggest Winners From the SpaceX IPO

Elon Musk isn’t the only big winner from the SpaceX SPCX 15.67%increase; up pointing triangle IPO. From longtime executives to short-term employees, college endowments and venture-capital firms, all stand to benefit from their stakes in the rocket maker.

Here’s a look at some of these winners.

Copyright ©2026 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7b1cdeb8

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The Faulty Logic Behind the SpaceX Index Trade

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The Faulty Logic Behind the SpaceX Index Trade

There are lots of reasons people bought SpaceX’s SPCX 19.22%increase; up pointing triangle $1.8 trillion IPO, including faith in Elon Musk, hopes for the first-day pop and, perhaps, a belief that it will one day profit from colonizing Mars. One idea that’s popular even with those who think the stock is wildly overvalued is that early entry into the Nasdaq-100 and several other large indexes is virtually a guarantee of free money.

The trade works like this: When SpaceX joins an index, funds tracking the index have to buy no matter the price. So if you buy in advance, you can then sell to the index fund at a higher price when it joins, which will be on Friday for some of the indexes. The demand part of the logic is impeccable, and index arbitragers have long done exactly this, albeit with risks that make it far from guaranteed money.

Copyright ©2026 Dow Jones & Company, Inc. All Rights Reserved. 87990cbe856818d5eddac44c7b1cdeb8

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Jefferies’ top power & utilities stock pick for 2026

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Jefferies’ top power & utilities stock pick for 2026

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Canada’s ambassador says trade talks with US are productive

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Canada’s ambassador says trade talks with US are productive

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Midwest and South states dominate 2026 housing affordability rankings

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Midwest and South states dominate 2026 housing affordability rankings

The states with the best affordability for homebuyers and that are facilitating the most construction of new homes are centered in the Midwest and South, according to a new report.

Realtor.com released the 2026 edition of its housing report cards for all 50 states plus the District of Columbia, which showed that states across the Midwest and South outperformed their peers from the Northeast and West.

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While no states earned an A+ grade, which suggests that all have room for improvement, 12 of the 13 states with the highest grades were all located in the Midwest and South, receiving grades in the B- to A range. Half of the grade is based on an affordability measure, while the other half is based on homebuilding activity.

“This year’s refresh reveals a familiar regional divide, but also some notable shifts beneath the surface, with a new state at the top of the class and a handful of states whose grades moved dramatically in either direction,” said Realtor.com senior economist Joel Berner.

MORTGAGE RATES TICK HIGHER, BUT BUYERS SHOW SIGNS OF CONFIDENCE

Homes under construction with storm in background

Realtor.com’s state report for housing affordability gave Indiana, Iowa and North Carolina A grades, while Texas received an A-. (Mark Felix/Bloomberg via Getty Images)

Indiana topped the list with a total score of 76.3 on the 100-point scale, earning an A based on strong affordability and homebuilding activity that helped it rise three spots from last year’s rankings. 

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The median-priced home in the Hoosier State was $295,810 and required about 28% of the median household income of $71,469, which fell below the 30% benchmark for affordability.

Other states to receive A grades include Iowa, which has a median listing price of $282,886 and a median household income of $75,991, as well as last year’s leader South Carolina, with a median listing price of $363,896 and a median income of $67,758.

WHY GEN Z IS SAYING ‘NO’ MORE OFTEN – AND SAVING MORE MONEY

Texas ranked fourth with an A- grade, given the Lone Star State’s median listing price of $364,749 and median income of $76,585. North Carolina and Nebraska were the only two states to receive B+ grades.

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The biggest risers in the report compared with last year were Delaware and Utah, which each jumped 12 spots. Delaware rose from 19th to 7th, while Utah saw its ranking rise from 29th to 17th.

Construction workers builds home with US flag in background

Realtor.com’s report is based on new construction activity as well as affordability metrics for buyers. (Joshua Lott/Bloomberg via Getty Images)

Six states received F grades on their report cards, with New York ranking last due to a $668,173 median listing price and median income of $82,657. The other five states that received F grades were all located in the Northeast or West, with Massachusetts, Rhode Island, Hawaii, California and Connecticut rounding out the bottom of the list in order of the worst grade to the best.

5 CITIES THAT NAIL THE RETIREMENT SWEET SPOT

Most of the states near the bottom of the rankings saw their rankings hold steady or change little from a year ago, as they continue to face high prices, limited land for building with restrictive zoning policies, and building costs outpacing what middle-income buyers can afford.

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The biggest drops were three states which all fell eight spots in the rankings – Alabama fell from 13th to 21st, Maryland dropped from 23rd to 31st, and New Jersey slipped from 35th to 43rd.

Homes in Queens.

New York slipped into last place in the 2026 rankings. (Lindsey Nicholson/UCG/Universal Images Group via Getty Images)

Here’s the list of the Realtor.com report’s grades for each of the 50 states as well as the District of Columbia:

  • Alabama: C
  • Alaska: C-
  • Arizona: C
  • Arkansas: B
  • California: F
  • Colorado: C+
  • Connecticut: F
  • Delaware: B
  • District of Columbia: D+
  • Florida: B
  • Georgia: B
  • Hawaii: F
  • Idaho: C
  • Illinois: C
  • Indiana: A
  • Iowa: A
  • Kansas: B
  • Kentucky: C
  • Louisiana: C
  • Maine: C-
  • Maryland: C
  • Massachusetts: F
  • Michigan: C
  • Minnesota: C+
  • Mississippi: C-
  • Missouri: C
  • Montana: D
  • Nebraska: B+
  • Nevada: C-
  • New Hampshire: D+
  • New Jersey: D
  • New Mexico: C-
  • New York: F
  • North Carolina: B+
  • North Dakota: C
  • Ohio: C+
  • Oklahoma: B
  • Oregon: D-
  • Pennsylvania: C
  • Rhode Island: F
  • South Carolina: A
  • South Dakota: B
  • Tennessee: C
  • Texas: A-
  • Utah: C+
  • Vermont: D+
  • Virginia: C+
  • Washington: C-
  • West Virginia: C
  • Wisconsin: C
  • Wyoming: C-

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‘Fire sale’ of council property ruled out as chiefs consider Eastern Avenue land

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Gloucester City Council looking to pay back emergency loan

General view of Eastern Avenue, Gloucester.

General view of Eastern Avenue, Gloucester(Image: Google)

There will be no “fire sale” of property say Gloucester chiefs as they agree to look at selling land in Eastern Avenue to pay back the emergency loan which saved the council from bankruptcy.

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Gloucester City Council leaders agreed last week to start the preparatory work to consider the feasibility of selling land and buildings at Eastern Avenue.

The authority was offered £15.5 million in exceptional financial support (EFS) from the Government earlier this year to balance its budget and avoid effective bankruptcy.

And selling off council-owned property or making them more profitable are part of the authority’s financial recovery plan.

The cabinet has agreed to appoint an agent to advise them on the potential sale of land.

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The precise property being considered for sale has not yet been made officially public but it is understood to be land is in and around the council’s depot in Chase Lane.

Finance cabinet member Declan Wilson (LD, Hucclecote) told the meeting on June 10 that a decision on whether the site is sold would be taken at a later date.

“The council’s financial recovery plan requires us to look carefully at our property assets and consider whether some could either generate a capital receipt or remove an ongoing liability,” he said.

He said the property was identified in the first phase of assets to be considered and the council will appoint an external agent to advise the council on the feasibility of selling the site.

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“This report does not yet commit the council to selling the site,” he added.

Gloucester City Council cabinet meeting on January 10, 2026.

Gloucester City Council’s cabinet meeting on January 10(Image: Local Democracy Reporting Service)

A further report with evidence on whether the property should or shouldn’t be put on the open market would be brought to the cabinet before any decision is made.

Council leader Jeremy Hilton (LD, Kingsholm and Wotton) said they are going to make sure they do a “thoroughly good job on the process”.

“We will find out whether it is viable for us to sell this land at Eastern Avenue,” he added.

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“It proves one thing, that this council is not about doing a fire sale.

“It’s about making sure we put things on the market, we do it properly and maximise the income for the asset.”

To find all the planning applications, traffic diversions, road layout changes, alcohol licence applications and more in your community, visit the Public Notices Portal.

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CoreWeave: The Liabilities Keep On Piling Up

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CoreWeave: The Liabilities Keep On Piling Up

CoreWeave: The Liabilities Keep On Piling Up

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