The Cleveland Guardians and the Kansas City Royals will continue their three-game divisional series on Tuesday at Progressive Field. Both teams are battling for early positioning in the American League Central.

The Royals won Game 1 on Monday, 4-2. Game 2 will start at 1:10 p.m. ET. Viewers can watch the game on Guardians.TV, Royals.TV and MLB.TV.

Cleveland Guardians vs Kansas City Royals odds

Money Line: Cleveland Guardians (-115), Kansas City Royals (-105)

Run Line: Cleveland Guardians +1.5 (-201), Kansas City Royals -1.5 (+165)

Total Runs: Over 7 (+100), Under 7 (-120)

(Source: DraftKings Sportsbook)

(NB: Odds are subject to change)

Preview – Starting Pitchers and Lineups

Cleveland Guardians starting pitcher

Gavin Williams will take the mound for the Cleveland Guardians. The righty pitcher has looked sharp in the early stages of the 2026 season. He carries a 2.25 ERA after two starts.

Williams relies on a high-velocity four-seam fastball that generated a significant whiff rate in his previous outing.

Kansas City Royals starting pitcher

Noah Cameron will start on the mound for the Kansas City Royals. The lefty pitcher is looking to build on a stellar season debut against the Minnesota Twins. He earned a win and maintained a 1.80 ERA.

Cameron’s ability to command his secondary pitches will be crucial against the Giardians’ lineup that excels in contact hitting.

Cleveland Guardians potential lineup

Left Field Steven Kwan (L)

Center Field Angel Martinez (S)

Third Base Jose Ramirez (S)

First Base Rhys Hoskins (R)

Designated Hitter David Fry (R)

Shortstop Gabriel Arias (R)

Right Field CJ Kayfus (L)

Second Base Brayan Rocchio (S)

Catcher Austin Hedges (R)

Kansas City Royals potential lineup

Third Base Maikel Garcia (R)

Shortstop Bobby Witt Jr. (R)

First Base Vinnie Pasquantino (L)

Catcher Salvador Perez (R)

Designated Hitter Carter Jensen (L)

Second Base Jonathan India (R)

Right Field Jac Caglianone (L)

Left Field Issac Collins (S)

Center Field Kyle Isbel (L)

(NB: S=Switch Hitter, R= Right-Handed Hitter, L=Left-Handed Hitter)

Prediction: Cleveland Guardians 4, Kansas City Royals 2

Gavin Williams has shown elite stuff early this season. His ability to overpower hitters should give him the advantage at home.

Noah Cameron has also been impressive. However, the Guardians lineup features several dangerous switch-hitters like Jose Ramirez, who can neutralize the lefty-on-lefty advantage.

With the Guardians playing at Progressive Field, they are the favorite to take Game 2 (Money Line: Cleveland Guardians (-115))

The Guardians pitching staff has been one of the most consistent in the league through the first two weeks. Both starters have ERAs under 2.30. Therefore, the likelihood of a low-scoring defensive battle is high (Total Runs: Under 7 (-120))

Expect the Guardians to lean on their bullpen to secure a narrow victory and cover the spread on the conservative side (Run Line: Guardians +1.5 (-201)