DUBLIN — Fuel protests gripping Ireland entered a fifth day Saturday as farmers, hauliers and truckers maintained blockades at key infrastructure sites, causing fuel shortages at hundreds of petrol stations and prompting the government to finalize a substantial support package for affected sectors.
Ireland Fuel Protests Enter Day 5 as Blockades Spark Shortages and Government Prepares Support Package
The demonstrations, which began April 7 in response to diesel and petrol prices surging more than 20% amid the U.S.-Iran conflict, have disrupted transport networks, supply chains and daily commutes nationwide. Tractors and heavy vehicles have blocked major roads including parts of the M50, O’Connell Street in Dublin, ports and the Whitegate oil refinery in County Cork.
Taoiseach Micheál Martin described the situation as “very severe,” warning that continued blockades could force Ireland to turn away fuel deliveries at a time of global supply strain. The government called in the army to assist with clearing key sites and declared the protests an “exceptional event” to bolster Garda resources.
Government Response and Ongoing Talks
After “constructive” meetings Friday with representatives from farming and haulage organizations, the government confirmed it is finalizing a significant financial support package. Tánaiste and Finance Minister Simon Harris described the measures as “substantial and significant” for key sectors including agriculture, transport and small businesses.
Talks are set to continue over the weekend. However, some protest organizers expressed skepticism, with one leader stating, “This is not going away” until concrete action addresses their demands. Several grassroots protesters were reportedly turned away from Friday’s meetings, highlighting tensions between official representative bodies and those on the ground.
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Protesters are demanding a fuel price cap, suspension or removal of carbon taxes on agricultural diesel, direct financial aid and even renewed oil exploration off Ireland’s west coast. Many say current costs threaten the viability of family farms and haulage businesses.
Impact on Fuel Supplies and Daily Life
Hundreds of service stations have already run dry, with estimates suggesting up to 600 forecourts could be affected by Saturday evening if blockades persist. Motorists have been urged to purchase only the fuel they need to avoid panic buying.
Emergency services faced challenges, though health officials reported ambulances were refueled overnight. Critical supply lines for animal feed and food distribution have also been disrupted, raising concerns for rural communities.
In Dublin, slow-moving convoys and static blockades brought parts of the city center to a standstill for days. Similar scenes unfolded in Cork, Galway, Limerick and Monaghan, where tractors blocked roundabouts and motorways.
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Roots of the Crisis
The protests erupted as global oil markets reacted to disruptions linked to the Iran conflict, which has squeezed supplies through the Strait of Hormuz. Ireland, heavily reliant on imports, saw diesel prices climb sharply, hitting farmers and hauliers particularly hard amid existing cost-of-living pressures.
Organizers include members of the Irish Farmers’ Association, Irish Creamery Milk Suppliers Association and independent hauliers. Many participants traveled long distances to join demonstrations, with one Cavan farmer telling reporters that fertilizer costs had jumped dramatically alongside fuel.
Broader Economic and Political Fallout
The disruptions come at a sensitive time for the Irish economy, which depends on efficient logistics for exports and tourism. Business groups have warned of mounting losses, while opposition politicians called for fuller engagement with protesters.
Gardaí have used public order units to remove some blockaders, including at Whitegate refinery, but tensions remain high. Some protesters formed human chains to block fuel tankers, leading to standoffs.
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The protests have drawn international attention as a stark example of how geopolitical events in the Middle East ripple into everyday life in Europe. Similar smaller actions have emerged in Norway, signaling wider discontent over energy costs.
What Happens Next
As negotiations intensify, the government faces pressure to balance immediate relief with long-term fiscal responsibility. Harris has rejected an immediate price cap, emphasizing targeted supports instead.
Protesters have signaled willingness to ease some blockades if meaningful progress emerges but warn they will “close the country” if demands are ignored. Many vow to sustain action into next week.
For ordinary citizens, the weekend outlook depends on whether supplies can be restored quickly. Motorists are advised to check fuel availability via apps and local stations before traveling, while rural areas brace for potential further shortages.
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The 2026 Irish fuel protests highlight deep vulnerabilities in energy security and the cost-of-living challenges facing rural and working-class communities. As talks continue, the coming days will determine whether compromise can end the blockades or if disruption will deepen.
Authorities continue to monitor the situation closely, with updates expected from both government officials and protest organizers throughout the weekend. For now, Ireland remains in a tense standoff between those feeling the sharp pain of rising fuel costs and a government scrambling to stabilize the situation without broader economic harm.
| Revenue of $58.82M (10.28% Y/Y) misses by $3.58M
Rigel Pharmaceuticals, Inc. (RIGL) M&A Call May 12, 2026 8:00 AM EDT
Company Participants
Raymond Furey – Executive VP, Chief Compliance Officer, General Counsel & Corporate Secretary Raul Rodriguez – President, CEO & Director Lisa Rojkjaer – Executive VP & Chief Medical Officer Erika Hamilton David Santos – Executive VP & Chief Commercial Officer
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Conference Call Participants
Joseph Pantginis – H.C. Wainwright & Co, LLC, Research Division Kristen Kluska – Cantor Fitzgerald & Co., Research Division Yigal Nochomovitz – Citigroup Inc., Research Division Farzin Haque – Jefferies LLC, Research Division Ashleigh Acker – Piper Sandler & Co., Research Division
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Presentation
Operator
Greetings. Welcome to Rigel Pharmaceutical VEPPANU Licensing Agreement Conference Call. [Operator Instructions] As a reminder, this conference is being recorded. It is now my pleasure to introduce our first speaker, Ray Furey, Rigel’s Executive Vice President, General Counsel and Corporate Secretary. Thank you, Mr. Furey. You may begin.
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Raymond Furey Executive VP, Chief Compliance Officer, General Counsel & Corporate Secretary
Welcome to our conference call to discuss Rigel’s in-licensing of VEPPANU or Vepdegestrant. The press release announcing the transaction was issued earlier this morning and can be viewed along with the slides for this presentation in the News and Events section of Investor Relations site on rigel.com.
As a reminder, during today’s call, we may make forward-looking statements regarding our plans and timing for the regulatory review of the transaction and development and commercialization of VEPPANU. In addition, as noted in the press release issued this morning and here in the presentation, this transaction is subject to customary closing conditions, including review under the Hart-Scott-Rodino Antitrust Improvements Act. The statements made today are subject to risks and uncertainties that may cause actual results to differ from those forecasted. A description of these risks are identified in the slides and in our most recent annual report on Form 10-K for the year ended December
Seeking Alpha’s transcripts team is responsible for the development of all of our transcript-related projects. We currently publish thousands of quarterly earnings calls per quarter on our site and are continuing to grow and expand our coverage. The purpose of this profile is to allow us to share with our readers new transcript-related developments. Thanks, SA Transcripts Team
| Revenue of -$29.00K (-100.96% Y/Y) misses by $109.31M
Vir Biotechnology, Inc. (VIR) Bank of America Global Healthcare Conference 2026 May 12, 2026 7:20 PM EDT
Company Participants
Marianne De Backer – President, CEO & Director
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Conference Call Participants
Alec Stranahan – BofA Securities, Research Division
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Presentation
Alec Stranahan BofA Securities, Research Division
Thanks for joining the session with Vir Biotechnology. My name is Alec Stranahan. I cover SMID-cap biotech at Bank of America, and I’m the covering analyst for Vir. And it’s my pleasure to introduce Marianne De Backer, Chief Executive Officer of Vir. Marianne, thanks for being here.
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Marianne De Backer President, CEO & Director
Yes, my pleasure. Thank you.
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Question-and-Answer Session
Alec Stranahan BofA Securities, Research Division
Looking forward to the discussion. I guess just jumping right into it, you’ve effectively built a 2-engine value story for Vir. You’ve got the near-term potential from HDV, which we can talk about and the longer-term oncology platform using the PRO-XTEN technology. I guess when you look at how the market is valuing the company today, where do you see the biggest opportunity for re-rating? Is it on HDV approval and launch? Is it on the VIR-5500 progress to registrational studies? Or is it maybe the broader platform as the TCE data matures?
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Marianne De Backer President, CEO & Director
Sure. Yes. Thank you. And thank you, Alec, for hosting us and Bank of America for hosting Vir Biotechnology. So we are very fortunate that at Vir Biotechnology, we have multiple pathways to value creation, as you point out. Obviously, our most advanced program is our delta program, already in registrational trial, initial data are going to read out starting fourth quarter of this year. So obviously, that’s an important route to value creation near term.
And then as you mentioned, we have a portfolio of 3 clinical assets, 3 clinical
Yesterday’s chaotic nine-goal thriller between Paris Saint-Germain and Bayern Munich completely shattered every conservative forecasting model on the market.
By examining the massive collapse of predictive algorithms during that specific match, business leaders can learn brutal, necessary lessons about surviving sudden operational chaos.
Corporate executives love to boast about making “calculated, data-driven decisions,” totally ignoring the fact that most financial forecasts are incredibly fragile. You can hire the most expensive analysts, build a massive spreadsheet and present a flawless quarterly projection to the board, but the reality of business is inherently volatile. When a massive supply chain failure or a sudden regulatory change hits your sector, the historical data is basically useless. To truly understand how quickly a supposedly perfect model can disintegrate, corporate leaders need to look outside the boardroom and study the aggressive, heavily scrutinized world of sports analytics. Yesterday’s Champions League clash is the absolute perfect case study.
No sane predictive model anticipated a 5-4 result between two European heavyweights. Examining the pre-match analytics on platforms like ThePuntersPage provides a brilliant corporate baseline, showing exactly what the smartest algorithms in the world expected to happen. They expected a tight, heavily defensive chess match. Instead, they got absolute pandemonium. Watching how the market reacted to that unexpected chaos offers a masterclass in modern risk management for any scaling enterprise.
The Illusion of the Safe Corporate Bet
Before the referee even blew the whistle in Paris, the financial narrative was already fully settled. Every major syndicate and data analyst backed the under on total goals. The logic was completely sound: semi-finals are notoriously tense, both squads possess world-class defensive structures and the stakes were simply too high for either manager to risk playing an open, attacking style. It was the textbook definition of a “safe bet.”
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This exact same mentality traps small and medium-sized enterprises every single day. Founders look at historical revenue charts and assume that because a specific product line or vendor relationship has been stable for three years, it will automatically remain stable for the fourth. They confuse historical consistency with future security. But relying entirely on past performance creates a massive operational blind spot. When you assume a market is safe, you stop aggressively monitoring the perimeter for threats. Just like the oddsmakers who totally failed to account for a sudden, aggressive tactical change in the first ten minutes of the match, companies that cling to their comfortable, safe bets are usually the first ones to get wiped out when the industry suddenly pivots.
Navigating the Black Swan Event
In financial terminology, a Black Swan is an unpredictable, incredibly rare event that carries severe consequences. Five goals being scored before the halftime whistle in a Champions League semi-final is the sporting equivalent of a Black Swan. It completely destroys the mathematical framework. When an event like this occurs, staring at your outdated dashboard and wondering why the numbers look wrong is a massive waste of time.
Corporate leaders constantly make the mistake of trusting the data even after the foundational reality has changed. According to a recent January 2026 financial analysison streamlining disconnected risk data, banks and massive corporations consistently fail to react to macroeconomic shocks because their internal reporting systems are too slow to process sudden, violent changes in the market. The algorithm cannot save you if the algorithm was built for a reality that no longer exists. When the match suddenly turns chaotic, or when a major competitor unexpectedly drops their pricing by forty percent, executives need to immediately abandon their rigid pre-planned models. Survival requires aggressive, real-time adaptation, totally disregarding the beautiful quarterly forecast that took three months to build.
Damage Control and the Art of Hedging
Perhaps the most valuable lesson from yesterday’s match is not how the models failed, but how Bayern Munich handled a catastrophic situation. Down 5-2 away from home, the German side was staring at total tournament elimination. An amateur manager would have panicked, thrown every single player forward and likely conceded three more goals on the counter-attack, completely bankrupting their chances for the second leg.
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Instead, they executed perfect damage control. They tightened their structure, absorbed the pressure and managed to claw back two late goals to make it 5-4, entirely saving the aggregate tie. This is exactly how ruthless founders manage a terrible financial quarter. If a new product launch is failing miserably, you do not double down and burn the rest of your venture capital trying to force it to work. You cut your losses, hedge your remaining assets and mitigate the damage so the company lives to fight another day. Reviewing strategies on mastering risk management as a trader directly translates to this executive mindset. It is about understanding that sometimes, the goal is not to win the quarter. No, the goal is simply to stop the bleeding before the damage becomes terminal.
Building an Agile Operational Framework
Business culture heavily romanticizes the maverick CEO who stubbornly sticks to their initial vision regardless of what the market dictates. In 2026, operating with that level of stubborn pride is borderline negligence. The market does not care about your initial vision, and it certainly does not care about your perfectly formatted Excel spreadsheets.
To survive in an increasingly volatile commercial environment, small and medium enterprises must transition away from rigid, multi-year plans and build highly agile frameworks. You train your management team to view corporate metrics with the same ruthless, emotionally detached objectivity found in the live sports forecasting industry. You learn to read the room, identify the exact moment the historical data becomes useless and pivot your resources without hesitation. Stop treating your business forecasts like an absolute guarantee. Treat them like a pre-match probability that can, and inevitably will, get blown to pieces the second the reality of the market kicks in.
| Revenue of $136.00M (-2.36% Y/Y) misses by $22.41M
Ultragenyx Pharmaceutical Inc. (RARE) Bank of America Global Healthcare Conference 2026 May 12, 2026 5:20 PM EDT
Company Participants
Howard Horn – Executive VP of Corporate Strategy & CFO Joshua Higa – Director of Investor Relations & Corporate Communications
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Presentation
Unknown Analyst
I’m one of the biotech analysts here at BofA. Our next presenting company is Ultragenyx. And here with me are Howard Horn, Chief Financial Officer; and Josh Higa, Head of IR. Thank you for joining us, guys.
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Question-and-Answer Session
Unknown Analyst
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So I think there’s a lot going on at the company. I think most people are familiar with it, but maybe we can start with a quick overview of the company, kind of your commercial products, and you have a very busy second half of the year. So maybe you can highlight some of the key catalysts coming up.
Howard Horn Executive VP of Corporate Strategy & CFO
Sure. Glad to, and thank you for having us. So Ultragenyx is a next-generation rare disease company on a pathway to profitability in 2027. We have 4 commercialized products, and we are estimating between $730 million and $760 million in revenue this year. We are hopeful to have 2 approvals and launches of 2 gene therapy programs this year. And the other data event people are waiting for is our Phase III data in Angelman that we talked about coming out in the second half of the year. So yes, it’s a very busy year.
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Unknown Analyst
All right. Great. Maybe we can start with a quick question on the commercial side. So you recently reported earnings. I think there was a slight miss in the quarter, but you reaffirmed your guidance for the year. Maybe you can talk to us a little bit about 1Q dynamics and kind of what gives you
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